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The map label for this gene is ilvH [H]

Identifier: 148643284

GI number: 148643284

Start: 1224659

End: 1225150

Strand: Reverse

Name: ilvH [H]

Synonym: Msm_1224

Alternate gene names: 148643284

Gene position: 1225150-1224659 (Counterclockwise)

Preceding gene: 148643285

Following gene: 148643283

Centisome position: 66.11

GC content: 31.71

Gene sequence:

>492_bases
ATGGCTTTAGAATATCATGTTATAAATGCATTAGTTGAAGATAAGCCGGGAGTATTGCAAAAAGTTGCTGGCCTATTTAC
AAGAAGAGGTTTTAACATTGATAGTATTACAGTTGGAGAATCTGAAGTTGAAGGATTGGCCCGTATGATTATCACTGTTA
AAGCAGATCAAAAATTATTGGAGCAAGTTACAAAACAACTGAATAAGCTTGTAGATGTTATTAAAATAAAAGATATCACT
GAAAATGCTGTTAAAAGAGAGTTATGTCTAGTTAAAGTTAATATTCCAAATGAAAAAGCTAGAGCAGAAATAATGCAGTA
TGTAAACATCTTTAGAGCTAAAATTGTAGATGTTTGTGAAGAAGCTTTAATTATTGAAATTACAGGTGACATTGAAAAGA
TAGATGCATTCCTATCCCTTTTAAAAGGATATGGTATTAAAAAGATTTCACGTACTGGTCTTACTGCAATGTCCCGTGGA
TTTCGTTCATGA

Upstream 100 bases:

>100_bases
AATTGATAAAGATGAAACTTTACCGATGGTGCCGCCAGGTGCAGCTATTGATGAAATGATTGGTGAATATAAACTTGAAA
AAGATGTATAGGTGAGTTAA

Downstream 100 bases:

>100_bases
TGATCCTTAATGAAATTTTGGAGAATAATAAGAAATTTGTAGATGAATTTGTAGGTGAGGAATTATCCCACCATCCCCAA
AAAAAGTTAGCTATCTTAAC

Product: acetolactate synthase, small subunit (regulatory), IlvH

Products: NA

Alternate protein names: Acetohydroxy-acid synthase small subunit; AHAS; ALS [H]

Number of amino acids: Translated: 163; Mature: 162

Protein sequence:

>163_residues
MALEYHVINALVEDKPGVLQKVAGLFTRRGFNIDSITVGESEVEGLARMIITVKADQKLLEQVTKQLNKLVDVIKIKDIT
ENAVKRELCLVKVNIPNEKARAEIMQYVNIFRAKIVDVCEEALIIEITGDIEKIDAFLSLLKGYGIKKISRTGLTAMSRG
FRS

Sequences:

>Translated_163_residues
MALEYHVINALVEDKPGVLQKVAGLFTRRGFNIDSITVGESEVEGLARMIITVKADQKLLEQVTKQLNKLVDVIKIKDIT
ENAVKRELCLVKVNIPNEKARAEIMQYVNIFRAKIVDVCEEALIIEITGDIEKIDAFLSLLKGYGIKKISRTGLTAMSRG
FRS
>Mature_162_residues
ALEYHVINALVEDKPGVLQKVAGLFTRRGFNIDSITVGESEVEGLARMIITVKADQKLLEQVTKQLNKLVDVIKIKDITE
NAVKRELCLVKVNIPNEKARAEIMQYVNIFRAKIVDVCEEALIIEITGDIEKIDAFLSLLKGYGIKKISRTGLTAMSRGF
RS

Specific function: Valine and isoleucine biosynthesis; first step. [C]

COG id: COG0440

COG function: function code E; Acetolactate synthase, small (regulatory) subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ACT domain [H]

Homologues:

Organism=Escherichia coli, GI1786266, Length=156, Percent_Identity=37.8205128205128, Blast_Score=115, Evalue=2e-27,
Organism=Saccharomyces cerevisiae, GI6319837, Length=203, Percent_Identity=27.5862068965517, Blast_Score=97, Evalue=1e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004789
- InterPro:   IPR019455
- InterPro:   IPR002912 [H]

Pfam domain/function: PF01842 ACT; PF10369 ALS_ss_C [H]

EC number: =2.2.1.6 [H]

Molecular weight: Translated: 18232; Mature: 18101

Theoretical pI: Translated: 9.12; Mature: 9.12

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MALEYHVINALVEDKPGVLQKVAGLFTRRGFNIDSITVGESEVEGLARMIITVKADQKLL
CCCHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCEEECCHHHHHHHHHHHHHHHHHHHHH
EQVTKQLNKLVDVIKIKDITENAVKRELCLVKVNIPNEKARAEIMQYVNIFRAKIVDVCE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHH
EALIIEITGDIEKIDAFLSLLKGYGIKKISRTGLTAMSRGFRS
HHEEEEECCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
ALEYHVINALVEDKPGVLQKVAGLFTRRGFNIDSITVGESEVEGLARMIITVKADQKLL
CCHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCEEECCHHHHHHHHHHHHHHHHHHHHH
EQVTKQLNKLVDVIKIKDITENAVKRELCLVKVNIPNEKARAEIMQYVNIFRAKIVDVCE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHH
EALIIEITGDIEKIDAFLSLLKGYGIKKISRTGLTAMSRGFRS
HHEEEEECCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9371463 [H]