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The map label for this gene is yggV [C]

Identifier: 148643255

GI number: 148643255

Start: 1193429

End: 1193977

Strand: Reverse

Name: yggV [C]

Synonym: Msm_1195

Alternate gene names: 148643255

Gene position: 1193977-1193429 (Counterclockwise)

Preceding gene: 148643258

Following gene: 148643254

Centisome position: 64.43

GC content: 32.79

Gene sequence:

>549_bases
ATGATAACATTTATAACTGGTAACAAACATAAAGTTATAGAAGCAGAGAATATATTTAAAGATTATGACATTAACTTAGA
GCATATTGATTTAGGTTACTGTGAACCTCAGGGAACTCTTGAGGAAGTAGCTATATCAGGTGCAAAATATGCCAGTCGTA
AACTTAATAAACCTGTGATTGTTGAAGATGCTGGTTTATTCATAAAAGCTTTAAAAGGTTTTCCTGGAACATATTCTTCT
TATGTTCAAGAAACTCTTGGAAATCAGGGAATATTAAAGCTTTTAGATGGTGTCAATGACCGTTATGCCGAATTCAGGTC
AGTTATTGGGTACTGCGCCCCCAATTCTGAGCCCAAGATCTTTTTAGGTAAGGTCATAGGTGAAATCGCAGTTGAAGAAA
AAGGAGATTTAGGTTTTGCTTTTGATCCTATTTTCTATGTTCCAGCTGAAGGTAAAACTTTTGGAGAACTTACAACTGAA
GAAAAAAACCAGTTTTCACATAGAAAAAATTCTTTAGAAAAATTTATTAAATGGTATTCTATTCAATAA

Upstream 100 bases:

>100_bases
TTTAGACCAGCTGAGCTTTCCTAAACAATGAATTGTTCATTTAAATCTTTTAACTGATTATGAGTTAATTTTATAAAAAA
TTTAATTCATAATTAATTTT

Downstream 100 bases:

>100_bases
TTTTCTAATTTATTATTATGGGCTTACTTTATAACTAATATTAAGAGGTAATTATTATGGCAAGACCAGAATGGGTAACT
TACAGTGATGAAGAAATTGA

Product: xanthosine triphosphate pyrophosphatase

Products: NA

Alternate protein names: Nucleoside triphosphate phosphohydrolase; NTPase [H]

Number of amino acids: Translated: 182; Mature: 182

Protein sequence:

>182_residues
MITFITGNKHKVIEAENIFKDYDINLEHIDLGYCEPQGTLEEVAISGAKYASRKLNKPVIVEDAGLFIKALKGFPGTYSS
YVQETLGNQGILKLLDGVNDRYAEFRSVIGYCAPNSEPKIFLGKVIGEIAVEEKGDLGFAFDPIFYVPAEGKTFGELTTE
EKNQFSHRKNSLEKFIKWYSIQ

Sequences:

>Translated_182_residues
MITFITGNKHKVIEAENIFKDYDINLEHIDLGYCEPQGTLEEVAISGAKYASRKLNKPVIVEDAGLFIKALKGFPGTYSS
YVQETLGNQGILKLLDGVNDRYAEFRSVIGYCAPNSEPKIFLGKVIGEIAVEEKGDLGFAFDPIFYVPAEGKTFGELTTE
EKNQFSHRKNSLEKFIKWYSIQ
>Mature_182_residues
MITFITGNKHKVIEAENIFKDYDINLEHIDLGYCEPQGTLEEVAISGAKYASRKLNKPVIVEDAGLFIKALKGFPGTYSS
YVQETLGNQGILKLLDGVNDRYAEFRSVIGYCAPNSEPKIFLGKVIGEIAVEEKGDLGFAFDPIFYVPAEGKTFGELTTE
EKNQFSHRKNSLEKFIKWYSIQ

Specific function: Hydrolyzes non-standard nucleotides such as XTP and dITP/ITP. Might exclude non-standard purines from DNA precursor pool, preventing thus incorporation into DNA and avoiding chromosomal lesions [H]

COG id: COG0127

COG function: function code F; Xanthosine triphosphate pyrophosphatase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HAM1 NTPase family [H]

Homologues:

Organism=Homo sapiens, GI15626999, Length=183, Percent_Identity=32.7868852459016, Blast_Score=89, Evalue=2e-18,
Organism=Homo sapiens, GI31657144, Length=155, Percent_Identity=32.9032258064516, Blast_Score=79, Evalue=2e-15,
Organism=Escherichia coli, GI1789324, Length=188, Percent_Identity=37.2340425531915, Blast_Score=99, Evalue=1e-22,
Organism=Caenorhabditis elegans, GI17556833, Length=180, Percent_Identity=32.7777777777778, Blast_Score=98, Evalue=3e-21,
Organism=Saccharomyces cerevisiae, GI6322529, Length=184, Percent_Identity=30.9782608695652, Blast_Score=76, Evalue=3e-15,
Organism=Drosophila melanogaster, GI19920712, Length=175, Percent_Identity=39.4285714285714, Blast_Score=108, Evalue=2e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002637
- InterPro:   IPR020922 [H]

Pfam domain/function: PF01725 Ham1p_like [H]

EC number: =3.6.1.15 [H]

Molecular weight: Translated: 20427; Mature: 20427

Theoretical pI: Translated: 5.11; Mature: 5.11

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
0.5 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
0.5 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MITFITGNKHKVIEAENIFKDYDINLEHIDLGYCEPQGTLEEVAISGAKYASRKLNKPVI
CEEEEECCCEEEEEHHHHHHCCCCCEEEEECCCCCCCCCHHHHHHCCCHHHHHHCCCCEE
VEDAGLFIKALKGFPGTYSSYVQETLGNQGILKLLDGVNDRYAEFRSVIGYCAPNSEPKI
EECCCHHHHHHCCCCCCHHHHHHHHHCCCHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCE
FLGKVIGEIAVEEKGDLGFAFDPIFYVPAEGKTFGELTTEEKNQFSHRKNSLEKFIKWYS
EHHHHHHHHHHCCCCCCCEEECCEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHC
IQ
CC
>Mature Secondary Structure
MITFITGNKHKVIEAENIFKDYDINLEHIDLGYCEPQGTLEEVAISGAKYASRKLNKPVI
CEEEEECCCEEEEEHHHHHHCCCCCEEEEECCCCCCCCCHHHHHHCCCHHHHHHCCCCEE
VEDAGLFIKALKGFPGTYSSYVQETLGNQGILKLLDGVNDRYAEFRSVIGYCAPNSEPKI
EECCCHHHHHHCCCCCCHHHHHHHHHCCCHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCE
FLGKVIGEIAVEEKGDLGFAFDPIFYVPAEGKTFGELTTEEKNQFSHRKNSLEKFIKWYS
EHHHHHHHHHHCCCCCCCEEECCEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHC
IQ
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11930014 [H]