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The map label for this gene is copA [H]

Identifier: 148643213

GI number: 148643213

Start: 1130562

End: 1133009

Strand: Reverse

Name: copA [H]

Synonym: Msm_1153

Alternate gene names: 148643213

Gene position: 1133009-1130562 (Counterclockwise)

Preceding gene: 148643214

Following gene: 148643210

Centisome position: 61.14

GC content: 33.42

Gene sequence:

>2448_bases
ATGGCAAAACTTAAAGAAATGGATTTGCCTATTGAAGGTATGCATTGTGCTTCCTGTGTTTTAAGTTTAAATAAAACTTT
TGAAAAGGTTGAAGGAGTGGAATCAGTAGATGCAGATTTGGCTTCAAATAAATTACATTTAACTGTCAATCCAAAAAAGC
TCCCATTTGATGAAATTGAAACATTAGTTAAAAATTTGGGATTTGAACTTCACACAGATGAGGTTACTCTTAAACTTAAC
GGAATGCATTGTGCTTCCTGTGTCATGAATGTTGAAAACTTTTTAATACGTTTAGACGGCATTTTTGATGTTAAGGCAGA
TTTAACTTCACAAACAGCACGTATCAATTATGATAAAACAAAAGTAACTGTCAAAGACATGGAAGAAGTTATTAATTCTT
TGGGATTTGAAGTACTTGGAATTGATGGGCAACTTGAAATAAATGAAGATGAAATTTATAAAAATGATTTAAAAGATAAA
AGAAATAGGATTATAGTTGGTTTTGCAGCATCAGCTGTTTTAATGGCTTTAATGTATATTCACTGGCATCCGTTTGGATT
GTCTATGGGAATAACTTCGTTAATCATAAGTATTCTTCCATTTCTTTATGTATCTTTACCTACACTTAAAGCAGGATTCA
ACGGTCTTGTTCATAAGAATTTAAACATGGATGTGATGTATTCGATGGGTATAACTGTTGCATACATATCAAGTATTTTG
GGAACATTTAACATAGTTCTTGATCATTCATTTATGTTTTATGAAACAGCTATTATGCTTCCATCATTTTTACTTATTGG
CAGATATTTGGAAGCAAAAGCTAAAAAGAAAACTTCTGATTCAATTCGAGAACTTATTGGTCTTCAGCCAACAGCAGCTA
CTTTAATAGAACTTGACAGTAATGGGAATATAGTGTCTCAAAAAGAGGTGAATATTAAAGAAATCCAAATTGGCGATATT
TTACTTGTTCGTCCGGGAGATAAAATACCTGTAGATGGTGAAGTAATCGGCGGACATTCTTATGTTGACGAATCAATGAT
TAATGGTGAACCAATTCCCAAAGCTAAAAGAGATGGTGAAGAAGTATTTGCAGGCACTATTAATCAGGATGGTGTTTTAC
ACATTAAAGCTAAAAAAATTGGCAGCAAAACTGTATTGTCAAATATTATCCGTTTAGTTGAAAAAGCTCAAAGTTCCAGA
CCTCCGGTTCAAAAATTAGCTAACACTGCAGTTAGCTATTTCATACCCACAATTTTAACAATAGCTGTTGTTGTATTCCT
GCTGTGGTACTTTGTATTTGACTCTACTTTGTTGTTTGCACTTACAACTTTAATTTCAATTTTAGTTGTGGCCTGTCCAT
GTGCATTAGGTCTGGCTACTCCGACAGCAGTAACTGTAGGTGTTGGTAGGGCTGCAGAATTTGGTATTCTTATTAAAAAT
GGAGATACTTTAGAAAATGCAGGTAAAATTGATGTTGCAGCATTTGATAAAACTGGAACTATAACTGAAGGTCAGCCTGA
AGTGGATGATGTTATATGTTATGGAATTAGTGAAAATGAATTGGTTGAACTTGCAGCCAGTGTAGAGAAAAATTCCAATC
ATCCAATAGCTAAGGCAATTGTCAGAAAAGCCAGTGATATGAATCTGGAACTTATTCGAACTTCATCATTTGAAAATATA
ACGGGTAAAGGTTTAAAAGCTCAGGTTAATGATAAAGATATTTTAGCAGGAAATAAAAAGCTTTTAGAATCTCAGGATAT
TGAAATTCCTCAAAGTGTTTTGGAAGAGTATGGAAGACTGGAGGACCTTAGTAAAACTATAATTTTAATAGGTGTTGATA
GGGAAATTAAAGGTATTTTAAGTTTATCTGATAAAATCAAAGCTAATTCTAAAAGAACTATTGAAGAATTGCATAAAATG
GGCATTGAAACATATATGCTTACAGGAGATAACAAAAAAACAGCATCAACTGTAGCCAGTGCAGTAGGTATTGATAATGT
ATGTGCCGGAGTTTTACCTGAAAACAAATTGGATATTGTTAAAAATCTTCAAAAAGAAGACAAGACAGTTTTATTTGTTG
GAGACGGTATTAATGATGCACCTGCACTTACACAGGCTAATATTGGTGTAGCTATGGGTAACGGAACAGATATTGCTATG
GAAAGTGGTGATATTGTTGTAATGGAAGGTGATTTGGAAAATGTAGTTGCTGCTGTGCAGTTTTCTAAAAAGGTAATGAC
TAGAATTAAAGAAAATTTATTCTGGGCATTTGCATATAATGTTATACTGATTCCACTTGCAGCAGGAGCGCTTTATGCCG
GTTTTGGAATAATGTTCATGCCTGAATGGTCTGCTCTTGCAATGGCATTAAGTTCAGTAACAGTCATATCCCTGTCACTT
GCTCTTAAAGGATATGTTCCTGCAATAAAAAAAGAAACAAAAAGTTAA

Upstream 100 bases:

>100_bases
TAGGTATACATAAATTTTTATTTAAGAAGTATACAATTTATATATGTGTGATTATTAATTTTAATCTGAAAATAATCTAT
TAAAATTTGGTTGTGATATA

Downstream 100 bases:

>100_bases
TTGATTTAATTGTCAATTAACTCTATTTTTAATTTTCCAAGTTTTGTAGCTAAAAAATTATAGAATATAGCTAAAAGACC
TCCACCTATAACTCCATTTA

Product: cation transporter HAD ATPase

Products: ADP; Orthophosphate. [C]

Alternate protein names: NA

Number of amino acids: Translated: 815; Mature: 814

Protein sequence:

>815_residues
MAKLKEMDLPIEGMHCASCVLSLNKTFEKVEGVESVDADLASNKLHLTVNPKKLPFDEIETLVKNLGFELHTDEVTLKLN
GMHCASCVMNVENFLIRLDGIFDVKADLTSQTARINYDKTKVTVKDMEEVINSLGFEVLGIDGQLEINEDEIYKNDLKDK
RNRIIVGFAASAVLMALMYIHWHPFGLSMGITSLIISILPFLYVSLPTLKAGFNGLVHKNLNMDVMYSMGITVAYISSIL
GTFNIVLDHSFMFYETAIMLPSFLLIGRYLEAKAKKKTSDSIRELIGLQPTAATLIELDSNGNIVSQKEVNIKEIQIGDI
LLVRPGDKIPVDGEVIGGHSYVDESMINGEPIPKAKRDGEEVFAGTINQDGVLHIKAKKIGSKTVLSNIIRLVEKAQSSR
PPVQKLANTAVSYFIPTILTIAVVVFLLWYFVFDSTLLFALTTLISILVVACPCALGLATPTAVTVGVGRAAEFGILIKN
GDTLENAGKIDVAAFDKTGTITEGQPEVDDVICYGISENELVELAASVEKNSNHPIAKAIVRKASDMNLELIRTSSFENI
TGKGLKAQVNDKDILAGNKKLLESQDIEIPQSVLEEYGRLEDLSKTIILIGVDREIKGILSLSDKIKANSKRTIEELHKM
GIETYMLTGDNKKTASTVASAVGIDNVCAGVLPENKLDIVKNLQKEDKTVLFVGDGINDAPALTQANIGVAMGNGTDIAM
ESGDIVVMEGDLENVVAAVQFSKKVMTRIKENLFWAFAYNVILIPLAAGALYAGFGIMFMPEWSALAMALSSVTVISLSL
ALKGYVPAIKKETKS

Sequences:

>Translated_815_residues
MAKLKEMDLPIEGMHCASCVLSLNKTFEKVEGVESVDADLASNKLHLTVNPKKLPFDEIETLVKNLGFELHTDEVTLKLN
GMHCASCVMNVENFLIRLDGIFDVKADLTSQTARINYDKTKVTVKDMEEVINSLGFEVLGIDGQLEINEDEIYKNDLKDK
RNRIIVGFAASAVLMALMYIHWHPFGLSMGITSLIISILPFLYVSLPTLKAGFNGLVHKNLNMDVMYSMGITVAYISSIL
GTFNIVLDHSFMFYETAIMLPSFLLIGRYLEAKAKKKTSDSIRELIGLQPTAATLIELDSNGNIVSQKEVNIKEIQIGDI
LLVRPGDKIPVDGEVIGGHSYVDESMINGEPIPKAKRDGEEVFAGTINQDGVLHIKAKKIGSKTVLSNIIRLVEKAQSSR
PPVQKLANTAVSYFIPTILTIAVVVFLLWYFVFDSTLLFALTTLISILVVACPCALGLATPTAVTVGVGRAAEFGILIKN
GDTLENAGKIDVAAFDKTGTITEGQPEVDDVICYGISENELVELAASVEKNSNHPIAKAIVRKASDMNLELIRTSSFENI
TGKGLKAQVNDKDILAGNKKLLESQDIEIPQSVLEEYGRLEDLSKTIILIGVDREIKGILSLSDKIKANSKRTIEELHKM
GIETYMLTGDNKKTASTVASAVGIDNVCAGVLPENKLDIVKNLQKEDKTVLFVGDGINDAPALTQANIGVAMGNGTDIAM
ESGDIVVMEGDLENVVAAVQFSKKVMTRIKENLFWAFAYNVILIPLAAGALYAGFGIMFMPEWSALAMALSSVTVISLSL
ALKGYVPAIKKETKS
>Mature_814_residues
AKLKEMDLPIEGMHCASCVLSLNKTFEKVEGVESVDADLASNKLHLTVNPKKLPFDEIETLVKNLGFELHTDEVTLKLNG
MHCASCVMNVENFLIRLDGIFDVKADLTSQTARINYDKTKVTVKDMEEVINSLGFEVLGIDGQLEINEDEIYKNDLKDKR
NRIIVGFAASAVLMALMYIHWHPFGLSMGITSLIISILPFLYVSLPTLKAGFNGLVHKNLNMDVMYSMGITVAYISSILG
TFNIVLDHSFMFYETAIMLPSFLLIGRYLEAKAKKKTSDSIRELIGLQPTAATLIELDSNGNIVSQKEVNIKEIQIGDIL
LVRPGDKIPVDGEVIGGHSYVDESMINGEPIPKAKRDGEEVFAGTINQDGVLHIKAKKIGSKTVLSNIIRLVEKAQSSRP
PVQKLANTAVSYFIPTILTIAVVVFLLWYFVFDSTLLFALTTLISILVVACPCALGLATPTAVTVGVGRAAEFGILIKNG
DTLENAGKIDVAAFDKTGTITEGQPEVDDVICYGISENELVELAASVEKNSNHPIAKAIVRKASDMNLELIRTSSFENIT
GKGLKAQVNDKDILAGNKKLLESQDIEIPQSVLEEYGRLEDLSKTIILIGVDREIKGILSLSDKIKANSKRTIEELHKMG
IETYMLTGDNKKTASTVASAVGIDNVCAGVLPENKLDIVKNLQKEDKTVLFVGDGINDAPALTQANIGVAMGNGTDIAME
SGDIVVMEGDLENVVAAVQFSKKVMTRIKENLFWAFAYNVILIPLAAGALYAGFGIMFMPEWSALAMALSSVTVISLSLA
LKGYVPAIKKETKS

Specific function: Probably involved in copper and silver export [H]

COG id: COG2217

COG function: function code P; Cation transport ATPase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 HMA domains [H]

Homologues:

Organism=Homo sapiens, GI115529486, Length=897, Percent_Identity=33.221850613155, Blast_Score=475, Evalue=1e-134,
Organism=Homo sapiens, GI55743071, Length=866, Percent_Identity=33.3718244803695, Blast_Score=463, Evalue=1e-130,
Organism=Homo sapiens, GI55743073, Length=749, Percent_Identity=32.7102803738318, Blast_Score=350, Evalue=5e-96,
Organism=Homo sapiens, GI118498343, Length=551, Percent_Identity=23.7749546279492, Blast_Score=100, Evalue=7e-21,
Organism=Homo sapiens, GI28373105, Length=193, Percent_Identity=29.0155440414508, Blast_Score=86, Evalue=1e-16,
Organism=Homo sapiens, GI28373109, Length=193, Percent_Identity=29.0155440414508, Blast_Score=86, Evalue=1e-16,
Organism=Homo sapiens, GI28373113, Length=193, Percent_Identity=29.0155440414508, Blast_Score=86, Evalue=1e-16,
Organism=Homo sapiens, GI28373103, Length=193, Percent_Identity=29.0155440414508, Blast_Score=86, Evalue=1e-16,
Organism=Homo sapiens, GI28373107, Length=193, Percent_Identity=29.0155440414508, Blast_Score=86, Evalue=1e-16,
Organism=Homo sapiens, GI28373115, Length=193, Percent_Identity=29.0155440414508, Blast_Score=86, Evalue=1e-16,
Organism=Homo sapiens, GI28373111, Length=193, Percent_Identity=29.0155440414508, Blast_Score=86, Evalue=1e-16,
Organism=Homo sapiens, GI10835220, Length=175, Percent_Identity=29.1428571428571, Blast_Score=82, Evalue=3e-15,
Organism=Homo sapiens, GI27886529, Length=175, Percent_Identity=29.1428571428571, Blast_Score=81, Evalue=3e-15,
Organism=Homo sapiens, GI48762685, Length=186, Percent_Identity=27.4193548387097, Blast_Score=80, Evalue=6e-15,
Organism=Homo sapiens, GI48762691, Length=186, Percent_Identity=27.4193548387097, Blast_Score=80, Evalue=6e-15,
Organism=Homo sapiens, GI48762689, Length=186, Percent_Identity=27.4193548387097, Blast_Score=80, Evalue=6e-15,
Organism=Homo sapiens, GI24638454, Length=175, Percent_Identity=28.5714285714286, Blast_Score=80, Evalue=7e-15,
Organism=Homo sapiens, GI4502285, Length=175, Percent_Identity=28.5714285714286, Blast_Score=80, Evalue=7e-15,
Organism=Homo sapiens, GI48762687, Length=186, Percent_Identity=27.4193548387097, Blast_Score=80, Evalue=7e-15,
Organism=Homo sapiens, GI209413709, Length=175, Percent_Identity=28.5714285714286, Blast_Score=80, Evalue=7e-15,
Organism=Homo sapiens, GI310128958, Length=169, Percent_Identity=29.585798816568, Blast_Score=79, Evalue=2e-14,
Organism=Homo sapiens, GI4502271, Length=308, Percent_Identity=25.3246753246753, Blast_Score=73, Evalue=1e-12,
Organism=Homo sapiens, GI237681109, Length=251, Percent_Identity=27.0916334661355, Blast_Score=71, Evalue=4e-12,
Organism=Homo sapiens, GI21361181, Length=251, Percent_Identity=27.0916334661355, Blast_Score=71, Evalue=4e-12,
Organism=Homo sapiens, GI237681111, Length=251, Percent_Identity=27.0916334661355, Blast_Score=71, Evalue=4e-12,
Organism=Homo sapiens, GI22748667, Length=251, Percent_Identity=25.8964143426295, Blast_Score=70, Evalue=7e-12,
Organism=Homo sapiens, GI297374799, Length=96, Percent_Identity=34.375, Blast_Score=70, Evalue=1e-11,
Organism=Homo sapiens, GI83700225, Length=96, Percent_Identity=34.375, Blast_Score=69, Evalue=1e-11,
Organism=Homo sapiens, GI48255959, Length=193, Percent_Identity=27.4611398963731, Blast_Score=69, Evalue=1e-11,
Organism=Homo sapiens, GI48255957, Length=193, Percent_Identity=27.4611398963731, Blast_Score=69, Evalue=1e-11,
Organism=Homo sapiens, GI153946397, Length=144, Percent_Identity=28.4722222222222, Blast_Score=67, Evalue=5e-11,
Organism=Escherichia coli, GI1786691, Length=844, Percent_Identity=33.6492890995261, Blast_Score=468, Evalue=1e-133,
Organism=Escherichia coli, GI1789879, Length=696, Percent_Identity=29.1666666666667, Blast_Score=296, Evalue=4e-81,
Organism=Escherichia coli, GI1786914, Length=507, Percent_Identity=29.3885601577909, Blast_Score=189, Evalue=6e-49,
Organism=Escherichia coli, GI2367363, Length=142, Percent_Identity=31.6901408450704, Blast_Score=72, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17556548, Length=890, Percent_Identity=32.1348314606742, Blast_Score=412, Evalue=1e-115,
Organism=Caenorhabditis elegans, GI17557486, Length=256, Percent_Identity=26.5625, Blast_Score=84, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI17557770, Length=251, Percent_Identity=26.2948207171315, Blast_Score=83, Evalue=5e-16,
Organism=Caenorhabditis elegans, GI32566766, Length=251, Percent_Identity=26.2948207171315, Blast_Score=83, Evalue=5e-16,
Organism=Caenorhabditis elegans, GI71997262, Length=582, Percent_Identity=22.8522336769759, Blast_Score=81, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17554158, Length=175, Percent_Identity=26.8571428571429, Blast_Score=78, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI193210130, Length=175, Percent_Identity=26.8571428571429, Blast_Score=78, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI71988506, Length=175, Percent_Identity=26.8571428571429, Blast_Score=78, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI193203356, Length=225, Percent_Identity=25.3333333333333, Blast_Score=78, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI193203354, Length=225, Percent_Identity=25.3333333333333, Blast_Score=78, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17559224, Length=338, Percent_Identity=24.8520710059172, Blast_Score=76, Evalue=6e-14,
Organism=Caenorhabditis elegans, GI17541776, Length=192, Percent_Identity=27.6041666666667, Blast_Score=75, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI71997275, Length=186, Percent_Identity=27.4193548387097, Blast_Score=75, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI71997269, Length=160, Percent_Identity=29.375, Blast_Score=72, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI71999440, Length=225, Percent_Identity=27.1111111111111, Blast_Score=71, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI71999438, Length=200, Percent_Identity=28, Blast_Score=70, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI25152707, Length=178, Percent_Identity=29.2134831460674, Blast_Score=70, Evalue=5e-12,
Organism=Saccharomyces cerevisiae, GI6320475, Length=891, Percent_Identity=33.2210998877666, Blast_Score=393, Evalue=1e-110,
Organism=Saccharomyces cerevisiae, GI6319772, Length=636, Percent_Identity=30.3459119496855, Blast_Score=291, Evalue=2e-79,
Organism=Saccharomyces cerevisiae, GI6321430, Length=539, Percent_Identity=24.1187384044527, Blast_Score=122, Evalue=2e-28,
Organism=Saccharomyces cerevisiae, GI6325221, Length=539, Percent_Identity=23.9332096474954, Blast_Score=120, Evalue=6e-28,
Organism=Saccharomyces cerevisiae, GI6321271, Length=186, Percent_Identity=31.1827956989247, Blast_Score=96, Evalue=2e-20,
Organism=Saccharomyces cerevisiae, GI6320244, Length=217, Percent_Identity=27.6497695852535, Blast_Score=86, Evalue=3e-17,
Organism=Saccharomyces cerevisiae, GI6320245, Length=217, Percent_Identity=27.6497695852535, Blast_Score=86, Evalue=3e-17,
Organism=Saccharomyces cerevisiae, GI6320243, Length=217, Percent_Identity=27.6497695852535, Blast_Score=86, Evalue=3e-17,
Organism=Saccharomyces cerevisiae, GI6321432, Length=184, Percent_Identity=27.1739130434783, Blast_Score=77, Evalue=2e-14,
Organism=Drosophila melanogaster, GI221329854, Length=626, Percent_Identity=32.7476038338658, Blast_Score=316, Evalue=3e-86,
Organism=Drosophila melanogaster, GI24668708, Length=161, Percent_Identity=31.055900621118, Blast_Score=89, Evalue=1e-17,
Organism=Drosophila melanogaster, GI24668696, Length=161, Percent_Identity=31.055900621118, Blast_Score=89, Evalue=1e-17,
Organism=Drosophila melanogaster, GI281366617, Length=161, Percent_Identity=31.055900621118, Blast_Score=89, Evalue=1e-17,
Organism=Drosophila melanogaster, GI24668704, Length=161, Percent_Identity=31.055900621118, Blast_Score=89, Evalue=1e-17,
Organism=Drosophila melanogaster, GI161085803, Length=161, Percent_Identity=31.055900621118, Blast_Score=89, Evalue=2e-17,
Organism=Drosophila melanogaster, GI17136664, Length=175, Percent_Identity=25.1428571428571, Blast_Score=74, Evalue=3e-13,
Organism=Drosophila melanogaster, GI24762455, Length=175, Percent_Identity=25.1428571428571, Blast_Score=74, Evalue=3e-13,
Organism=Drosophila melanogaster, GI24762453, Length=175, Percent_Identity=25.1428571428571, Blast_Score=74, Evalue=3e-13,
Organism=Drosophila melanogaster, GI24762447, Length=175, Percent_Identity=25.1428571428571, Blast_Score=74, Evalue=3e-13,
Organism=Drosophila melanogaster, GI24762457, Length=175, Percent_Identity=25.1428571428571, Blast_Score=74, Evalue=3e-13,
Organism=Drosophila melanogaster, GI24762449, Length=175, Percent_Identity=25.1428571428571, Blast_Score=74, Evalue=3e-13,
Organism=Drosophila melanogaster, GI24762445, Length=175, Percent_Identity=25.1428571428571, Blast_Score=74, Evalue=3e-13,
Organism=Drosophila melanogaster, GI24762451, Length=175, Percent_Identity=25.1428571428571, Blast_Score=74, Evalue=3e-13,
Organism=Drosophila melanogaster, GI281366676, Length=217, Percent_Identity=24.4239631336406, Blast_Score=72, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24648576, Length=309, Percent_Identity=24.9190938511327, Blast_Score=68, Evalue=2e-11,
Organism=Drosophila melanogaster, GI281362164, Length=309, Percent_Identity=24.9190938511327, Blast_Score=68, Evalue=3e-11,
Organism=Drosophila melanogaster, GI45553435, Length=309, Percent_Identity=24.9190938511327, Blast_Score=68, Evalue=3e-11,
Organism=Drosophila melanogaster, GI45553439, Length=309, Percent_Identity=24.9190938511327, Blast_Score=68, Evalue=3e-11,
Organism=Drosophila melanogaster, GI45553441, Length=309, Percent_Identity=24.9190938511327, Blast_Score=68, Evalue=3e-11,
Organism=Drosophila melanogaster, GI24648580, Length=309, Percent_Identity=24.9190938511327, Blast_Score=68, Evalue=3e-11,
Organism=Drosophila melanogaster, GI24648578, Length=309, Percent_Identity=24.9190938511327, Blast_Score=68, Evalue=3e-11,
Organism=Drosophila melanogaster, GI45553437, Length=309, Percent_Identity=24.9190938511327, Blast_Score=68, Evalue=3e-11,
Organism=Drosophila melanogaster, GI24648582, Length=309, Percent_Identity=24.9190938511327, Blast_Score=67, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008250
- InterPro:   IPR006403
- InterPro:   IPR006416
- InterPro:   IPR001757
- InterPro:   IPR018303
- InterPro:   IPR006122
- InterPro:   IPR005834
- InterPro:   IPR023214
- InterPro:   IPR017969
- InterPro:   IPR006121 [H]

Pfam domain/function: PF00122 E1-E2_ATPase; PF00403 HMA; PF00702 Hydrolase [H]

EC number: 3.6.3.4 [C]

Molecular weight: Translated: 88671; Mature: 88540

Theoretical pI: Translated: 5.01; Mature: 5.01

Prosite motif: PS00154 ATPASE_E1_E2 ; PS01047 HMA_1 ; PS50846 HMA_2 ; PS01229 COF_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKLKEMDLPIEGMHCASCVLSLNKTFEKVEGVESVDADLASNKLHLTVNPKKLPFDEIE
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCEEEEEECCCCCCHHHHH
TLVKNLGFELHTDEVTLKLNGMHCASCVMNVENFLIRLDGIFDVKADLTSQTARINYDKT
HHHHHCCCEEECCEEEEEECCCHHHHHHHHHHHHHEEECCEEEECCCCCCCCEEEECCCC
KVTVKDMEEVINSLGFEVLGIDGQLEINEDEIYKNDLKDKRNRIIVGFAASAVLMALMYI
EEEHHHHHHHHHHCCCEEEECCCEEEECHHHHHHHHHHHCCCEEEEEEHHHHHHHHHHHH
HWHPFGLSMGITSLIISILPFLYVSLPTLKAGFNGLVHKNLNMDVMYSMGITVAYISSIL
HCCCCCHHHHHHHHHHHHHHHHHHHCHHHHHCCCCEEECCCCCEEEECCCHHHHHHHHHH
GTFNIVLDHSFMFYETAIMLPSFLLIGRYLEAKAKKKTSDSIRELIGLQPTAATLIELDS
HHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCEEEEEECC
NGNIVSQKEVNIKEIQIGDILLVRPGDKIPVDGEVIGGHSYVDESMINGEPIPKAKRDGE
CCCEEEECCCCEEEEEECCEEEECCCCCCCCCCEEECCCHHHHHHHCCCCCCCCCCCCCC
EVFAGTINQDGVLHIKAKKIGSKTVLSNIIRLVEKAQSSRPPVQKLANTAVSYFIPTILT
HHEEECCCCCCEEEEEEHHCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHH
IAVVVFLLWYFVFDSTLLFALTTLISILVVACPCALGLATPTAVTVGVGRAAEFGILIKN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCEEEEEEEC
GDTLENAGKIDVAAFDKTGTITEGQPEVDDVICYGISENELVELAASVEKNSNHPIAKAI
CCCCCCCCCEEEEEECCCCCCCCCCCCCCCEEEECCCHHHHHHHHHHHHCCCCCHHHHHH
VRKASDMNLELIRTSSFENITGKGLKAQVNDKDILAGNKKLLESQDIEIPQSVLEEYGRL
HHHCCCCCEEEEEECCCCCCCCCCCEEECCCCCEECCCHHHHCCCCCCCHHHHHHHHHCH
EDLSKTIILIGVDREIKGILSLSDKIKANSKRTIEELHKMGIETYMLTGDNKKTASTVAS
HHCCCEEEEEECCHHHHHHHHHHHHHCCCCHHHHHHHHHCCCEEEEEECCCCHHHHHHHH
AVGIDNVCAGVLPENKLDIVKNLQKEDKTVLFVGDGINDAPALTQANIGVAMGNGTDIAM
HHCHHHHHHCCCCCCHHHHHHHHHCCCCEEEEEECCCCCCCCCEECCCEEEECCCCEEEE
ESGDIVVMEGDLENVVAAVQFSKKVMTRIKENLFWAFAYNVILIPLAAGALYAGFGIMFM
ECCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEC
PEWSALAMALSSVTVISLSLALKGYVPAIKKETKS
CCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCC
>Mature Secondary Structure 
AKLKEMDLPIEGMHCASCVLSLNKTFEKVEGVESVDADLASNKLHLTVNPKKLPFDEIE
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCEEEEEECCCCCCHHHHH
TLVKNLGFELHTDEVTLKLNGMHCASCVMNVENFLIRLDGIFDVKADLTSQTARINYDKT
HHHHHCCCEEECCEEEEEECCCHHHHHHHHHHHHHEEECCEEEECCCCCCCCEEEECCCC
KVTVKDMEEVINSLGFEVLGIDGQLEINEDEIYKNDLKDKRNRIIVGFAASAVLMALMYI
EEEHHHHHHHHHHCCCEEEECCCEEEECHHHHHHHHHHHCCCEEEEEEHHHHHHHHHHHH
HWHPFGLSMGITSLIISILPFLYVSLPTLKAGFNGLVHKNLNMDVMYSMGITVAYISSIL
HCCCCCHHHHHHHHHHHHHHHHHHHCHHHHHCCCCEEECCCCCEEEECCCHHHHHHHHHH
GTFNIVLDHSFMFYETAIMLPSFLLIGRYLEAKAKKKTSDSIRELIGLQPTAATLIELDS
HHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCEEEEEECC
NGNIVSQKEVNIKEIQIGDILLVRPGDKIPVDGEVIGGHSYVDESMINGEPIPKAKRDGE
CCCEEEECCCCEEEEEECCEEEECCCCCCCCCCEEECCCHHHHHHHCCCCCCCCCCCCCC
EVFAGTINQDGVLHIKAKKIGSKTVLSNIIRLVEKAQSSRPPVQKLANTAVSYFIPTILT
HHEEECCCCCCEEEEEEHHCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHH
IAVVVFLLWYFVFDSTLLFALTTLISILVVACPCALGLATPTAVTVGVGRAAEFGILIKN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCEEEEEEEC
GDTLENAGKIDVAAFDKTGTITEGQPEVDDVICYGISENELVELAASVEKNSNHPIAKAI
CCCCCCCCCEEEEEECCCCCCCCCCCCCCCEEEECCCHHHHHHHHHHHHCCCCCHHHHHH
VRKASDMNLELIRTSSFENITGKGLKAQVNDKDILAGNKKLLESQDIEIPQSVLEEYGRL
HHHCCCCCEEEEEECCCCCCCCCCCEEECCCCCEECCCHHHHCCCCCCCHHHHHHHHHCH
EDLSKTIILIGVDREIKGILSLSDKIKANSKRTIEELHKMGIETYMLTGDNKKTASTVAS
HHCCCEEEEEECCHHHHHHHHHHHHHCCCCHHHHHHHHHCCCEEEEEECCCCHHHHHHHH
AVGIDNVCAGVLPENKLDIVKNLQKEDKTVLFVGDGINDAPALTQANIGVAMGNGTDIAM
HHCHHHHHHCCCCCCHHHHHHHHHCCCCEEEEEECCCCCCCCCEECCCEEEECCCCEEEE
ESGDIVVMEGDLENVVAAVQFSKKVMTRIKENLFWAFAYNVILIPLAAGALYAGFGIMFM
ECCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEC
PEWSALAMALSSVTVISLSLALKGYVPAIKKETKS
CCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: Cu [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; H2O [C]

Specific reaction: ATP + H2O = ADP + Orthophosphate. [C]

General reaction: Phosphorous acid anhydride hydrolysis [C]

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9389475 [H]