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The map label for this gene is cobY [H]

Identifier: 148643065

GI number: 148643065

Start: 970069

End: 970686

Strand: Reverse

Name: cobY [H]

Synonym: Msm_1005

Alternate gene names: 148643065

Gene position: 970686-970069 (Counterclockwise)

Preceding gene: 148643066

Following gene: 148643064

Centisome position: 52.38

GC content: 28.8

Gene sequence:

>618_bases
ATGATTTATGCTATTGTTATGGCTGGAGGTAGGGGAACTCGTCTAAAAGTTGATGTTGAAAAACCTCTATTTAAATTACA
TGGCAAACCTTTAATTAAATATGTTCTTGATAATATTTCTTCATCTAAATTAGTTGAAGATGTTGTTATTGCCGTAAGCC
CCCATACTCAGGAAACAACCAAATATTTAAAATCATTAAATGGCAATTTTCAAATTTTAAATACTTCTGGAATTGACTAT
TTAAATGATTTATCTTATATTTTAACTCTTTTTGAGTCCAAATCAAAAAAGGACACATTATTGTTTATTAATGCTGATTT
GCCGTTTGTCAGTGGTGAAACTATTGATTTTATACTGACTAACTATTTGGAATCCAGTAAAGATTCACTGTCTGCACAGG
TTCCGGTTGAAATTTTTAAAAAATTAGATTTGAAGTATTCTTATGAATTTAATGGTGCGGTACCTTCTGGTGTGAATGTT
TTAAGAAGTATTAATGAAATTCAGGATGAAGATCAGCTTATTTTGCCCAAAATTGAATTGGCATTAAATATTAATACTCT
TAAAGACAGTATCGTTGCTGAAAAATTTTATCAGGCTTTCATTAATAAAACTATTTAA

Upstream 100 bases:

>100_bases
ATCACCTATTGGAGGCTGCCAAGGTCAGAAATGTATTCTCGGTAAGAGGATGAAATTGCAGGGCAGCAAATATGCATAAT
TGATTCTAAAGGTTTTTGTC

Downstream 100 bases:

>100_bases
ATTTAAATATGATGAAATTAAAATATTTTATATAATTAATGAAAATTTATCAGGTGATGTGATGGAAAACAAACAAATTC
CTAAAAGAGAAGAAAAGTTA

Product: GTP:adenosylcobinamide-phosphate guanylyltransferase

Products: NA

Alternate protein names: AdoCbi-P guanylyltransferase [H]

Number of amino acids: Translated: 205; Mature: 205

Protein sequence:

>205_residues
MIYAIVMAGGRGTRLKVDVEKPLFKLHGKPLIKYVLDNISSSKLVEDVVIAVSPHTQETTKYLKSLNGNFQILNTSGIDY
LNDLSYILTLFESKSKKDTLLFINADLPFVSGETIDFILTNYLESSKDSLSAQVPVEIFKKLDLKYSYEFNGAVPSGVNV
LRSINEIQDEDQLILPKIELALNINTLKDSIVAEKFYQAFINKTI

Sequences:

>Translated_205_residues
MIYAIVMAGGRGTRLKVDVEKPLFKLHGKPLIKYVLDNISSSKLVEDVVIAVSPHTQETTKYLKSLNGNFQILNTSGIDY
LNDLSYILTLFESKSKKDTLLFINADLPFVSGETIDFILTNYLESSKDSLSAQVPVEIFKKLDLKYSYEFNGAVPSGVNV
LRSINEIQDEDQLILPKIELALNINTLKDSIVAEKFYQAFINKTI
>Mature_205_residues
MIYAIVMAGGRGTRLKVDVEKPLFKLHGKPLIKYVLDNISSSKLVEDVVIAVSPHTQETTKYLKSLNGNFQILNTSGIDY
LNDLSYILTLFESKSKKDTLLFINADLPFVSGETIDFILTNYLESSKDSLSAQVPVEIFKKLDLKYSYEFNGAVPSGVNV
LRSINEIQDEDQLILPKIELALNINTLKDSIVAEKFYQAFINKTI

Specific function: Guanylyltransferase that catalyzes the synthesis of adenosylcobinamide-GDP (AdoCbi-GDP) from adenosylcobinamide- phosphate (AdoCbi-P) and GTP. Is involved in adenosylcobalamin biosynthesis. Binds one GTP per dimer. Can not use other NTPs or GDP. Does not

COG id: COG2266

COG function: function code H; GTP:adenosylcobinamide-phosphate guanylyltransferase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005245
- InterPro:   IPR005835 [H]

Pfam domain/function: PF00483 NTP_transferase [H]

EC number: =2.7.7.62 [H]

Molecular weight: Translated: 23015; Mature: 23015

Theoretical pI: Translated: 5.34; Mature: 5.34

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIYAIVMAGGRGTRLKVDVEKPLFKLHGKPLIKYVLDNISSSKLVEDVVIAVSPHTQETT
CEEEEEEECCCCCEEEEECCCHHHHHCCCHHHHHHHHCCCCHHHHHHEEEEECCCCHHHH
KYLKSLNGNFQILNTSGIDYLNDLSYILTLFESKSKKDTLLFINADLPFVSGETIDFILT
HHHHHCCCCEEEEECCCCCHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCHHHHHHH
NYLESSKDSLSAQVPVEIFKKLDLKYSYEFNGAVPSGVNVLRSINEIQDEDQLILPKIEL
HHHHCCCHHCCCCCCHHHHHHCCCEEEEEECCCCCHHHHHHHHHHHHCCCCCEEEEEEEE
ALNINTLKDSIVAEKFYQAFINKTI
EEEEHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MIYAIVMAGGRGTRLKVDVEKPLFKLHGKPLIKYVLDNISSSKLVEDVVIAVSPHTQETT
CEEEEEEECCCCCEEEEECCCHHHHHCCCHHHHHHHHCCCCHHHHHHEEEEECCCCHHHH
KYLKSLNGNFQILNTSGIDYLNDLSYILTLFESKSKKDTLLFINADLPFVSGETIDFILT
HHHHHCCCCEEEEECCCCCHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCHHHHHHH
NYLESSKDSLSAQVPVEIFKKLDLKYSYEFNGAVPSGVNVLRSINEIQDEDQLILPKIEL
HHHHCCCHHCCCCCCHHHHHHCCCEEEEEECCCCCHHHHHHHHHHHHCCCCCEEEEEEEE
ALNINTLKDSIVAEKFYQAFINKTI
EEEEHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]