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The map label for this gene is mrtA [H]

Identifier: 148642962

GI number: 148642962

Start: 864381

End: 866036

Strand: Reverse

Name: mrtA [H]

Synonym: Msm_0902

Alternate gene names: 148642962

Gene position: 866036-864381 (Counterclockwise)

Preceding gene: 148642963

Following gene: 148642961

Centisome position: 46.73

GC content: 36.41

Gene sequence:

>1656_bases
ATGGAGAATGAGGAAAAAGTATTCTTCAAAGCTTTAAATCAAAAATTTAAAGGTGAAGATAATGAAAGTAACCACACCAG
TTTCTATTGTTTTGATGGGTGGAAGCAGTCTCCAAGAAAAAGAGAGTTTAATGATGCTGCAGAAAAATTAGCTAAAGATA
GGAATATGCCTTTTTATAATCCGGATATTGGTGTTCCTTTAGGTCAGAGAAGTTTAATGACTTATAAAATTTCCGGAACT
GATGATTATGTTGAAGGCGATGATTTGCATTTTTGTAACAATGCAGCTATTCAACAATTGGTTGACGATATTAAAAGAAC
AATTATTGTAGGTATGGATACTGCACACTCTGTTTTGCAGGAAAGATTAGGTGTGGAAGTAACTCCTGAAACAATCAATG
AATATATGGAGAATATCAATCATGCACTTCCTGGTGGAGCAGTAGTTCAGGAACATATGGTTGAAGTGCATCCTGGTTTA
GTTAGTGACTGTTATGCAAAAATTTTCACAGGTAATGATGAGTTGGCTGATGAAATAGATAAAAGAGTATTAATTGATAT
TAATAAAGAGTTCCCGGAAGATCAGGCACAAATGCTTAAAGATTATCTCGGAAACAAAACATATCAGGTTAGTAGAGTGC
CTACATTAGTTGTAAGGGCATGTGACGGAGGTACTGTATCCAGATGGTCTGCTATGCAGATTGGTATGAGTTTTATTAAT
GCATATAAATTATGTGCTGGTGAAGCAGCTATTGCAGATTTTTCTTATGCTGCTAAACATGCAGATGTTATTGGTATGGC
TTCATTTTTACCTGCTAGGCGTGCGAGAGGACCAAATGAGCCTGGAGGCGTTTCATTTGGTGCTTTTTCAGATATGATTC
AAACTTCAAGAATTTCTGATGATCCTGCTGAAGTAACATTGGAGGTTATTGCAGGTGCTGCTGCGCTATATGATCAGGTT
TGGTTAGGTTCTTACATGTCAGGAGGTGTAGGTTTCACTCAGTATGCAAGTGCAACTTATACTGATGATATTTTAGATGA
CTTTGTTTATTATGGTTTGGATTATGTTGAGGATAACTACGGTTTATGTCAGGCTGAAAAAACTATGGATGTTGTAAGGG
ATATTTCAACAGAAGTAACACTTTATGGTTTAGAACAATATGAAATACCTACTCTTCTTGAAACTCATTTCGGAGGTTCA
CAAAGGGCATCAGTTATATCTGCAGCTGCAGGATGTTCCACAGCTTTTGCAACAGCAAATTCCAATGCTGGTGTAAATGG
CTGGTATTTAAGTATGCTTTTACATAAGGAAGGACATTCAAGATTAGGATTCTATGGATATGACTTGCAAGACCAGTGCG
GTTCTGCTAATTCATTATCTATTAGAAGTGATGAAGGTTTAATTCATGAATTAAGAGGACCAAACTATCCGAACTATGCT
ATGAATGTAGGTCACCAGCCAGAATATGCAGGTATTGCACAGGCACCTCATGCTGCAAGAAAAGATGCATTTTCTGTTAA
TCCTTTAATAAAAATTGCATTTGCAGATGATGCATTATCTTTTGATTTTAAACATCCTAGAAAAGAGATTGCAAGAGGAG
CATTAAGAGAATTTGAGCCGGACGGTGAAAGGGATATTATAATTCCTGCAAAATAA

Upstream 100 bases:

>100_bases
GCTGTTGATATTGTTGAAACTATTCATTCATCTCGTACAAAAGGCGGTTATGGTTTAGGAGTTTTCAGTAAAGATTTAAA
AATGAGATTAGGTGAATATG

Downstream 100 bases:

>100_bases
TTCTCTTCTTTTTTCTTTTTTTTACTTTAAATTTATTGTTTTTTCTTTATCTTAATTTTGAAATTCTCTATTGAAAAATC
AGGTTTTCATGTTTTTGTTA

Product: methyl-coenzyme M reductase, alpha subunit, McrA

Products: NA

Alternate protein names: MCR II alpha; Coenzyme-B sulfoethylthiotransferase alpha [H]

Number of amino acids: Translated: 551; Mature: 551

Protein sequence:

>551_residues
MENEEKVFFKALNQKFKGEDNESNHTSFYCFDGWKQSPRKREFNDAAEKLAKDRNMPFYNPDIGVPLGQRSLMTYKISGT
DDYVEGDDLHFCNNAAIQQLVDDIKRTIIVGMDTAHSVLQERLGVEVTPETINEYMENINHALPGGAVVQEHMVEVHPGL
VSDCYAKIFTGNDELADEIDKRVLIDINKEFPEDQAQMLKDYLGNKTYQVSRVPTLVVRACDGGTVSRWSAMQIGMSFIN
AYKLCAGEAAIADFSYAAKHADVIGMASFLPARRARGPNEPGGVSFGAFSDMIQTSRISDDPAEVTLEVIAGAAALYDQV
WLGSYMSGGVGFTQYASATYTDDILDDFVYYGLDYVEDNYGLCQAEKTMDVVRDISTEVTLYGLEQYEIPTLLETHFGGS
QRASVISAAAGCSTAFATANSNAGVNGWYLSMLLHKEGHSRLGFYGYDLQDQCGSANSLSIRSDEGLIHELRGPNYPNYA
MNVGHQPEYAGIAQAPHAARKDAFSVNPLIKIAFADDALSFDFKHPRKEIARGALREFEPDGERDIIIPAK

Sequences:

>Translated_551_residues
MENEEKVFFKALNQKFKGEDNESNHTSFYCFDGWKQSPRKREFNDAAEKLAKDRNMPFYNPDIGVPLGQRSLMTYKISGT
DDYVEGDDLHFCNNAAIQQLVDDIKRTIIVGMDTAHSVLQERLGVEVTPETINEYMENINHALPGGAVVQEHMVEVHPGL
VSDCYAKIFTGNDELADEIDKRVLIDINKEFPEDQAQMLKDYLGNKTYQVSRVPTLVVRACDGGTVSRWSAMQIGMSFIN
AYKLCAGEAAIADFSYAAKHADVIGMASFLPARRARGPNEPGGVSFGAFSDMIQTSRISDDPAEVTLEVIAGAAALYDQV
WLGSYMSGGVGFTQYASATYTDDILDDFVYYGLDYVEDNYGLCQAEKTMDVVRDISTEVTLYGLEQYEIPTLLETHFGGS
QRASVISAAAGCSTAFATANSNAGVNGWYLSMLLHKEGHSRLGFYGYDLQDQCGSANSLSIRSDEGLIHELRGPNYPNYA
MNVGHQPEYAGIAQAPHAARKDAFSVNPLIKIAFADDALSFDFKHPRKEIARGALREFEPDGERDIIIPAK
>Mature_551_residues
MENEEKVFFKALNQKFKGEDNESNHTSFYCFDGWKQSPRKREFNDAAEKLAKDRNMPFYNPDIGVPLGQRSLMTYKISGT
DDYVEGDDLHFCNNAAIQQLVDDIKRTIIVGMDTAHSVLQERLGVEVTPETINEYMENINHALPGGAVVQEHMVEVHPGL
VSDCYAKIFTGNDELADEIDKRVLIDINKEFPEDQAQMLKDYLGNKTYQVSRVPTLVVRACDGGTVSRWSAMQIGMSFIN
AYKLCAGEAAIADFSYAAKHADVIGMASFLPARRARGPNEPGGVSFGAFSDMIQTSRISDDPAEVTLEVIAGAAALYDQV
WLGSYMSGGVGFTQYASATYTDDILDDFVYYGLDYVEDNYGLCQAEKTMDVVRDISTEVTLYGLEQYEIPTLLETHFGGS
QRASVISAAAGCSTAFATANSNAGVNGWYLSMLLHKEGHSRLGFYGYDLQDQCGSANSLSIRSDEGLIHELRGPNYPNYA
MNVGHQPEYAGIAQAPHAARKDAFSVNPLIKIAFADDALSFDFKHPRKEIARGALREFEPDGERDIIIPAK

Specific function: Reduction of methyl-coenzyme M (2-(methylthio) ethanesulfonic acid) with 7-mercaptoheptanoylthreonine phosphate to methane and an heterodisulfide [H]

COG id: COG4058

COG function: function code H; Methyl coenzyme M reductase, alpha subunit

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022681
- InterPro:   IPR016212
- InterPro:   IPR008924
- InterPro:   IPR009047
- InterPro:   IPR003183
- InterPro:   IPR015811
- InterPro:   IPR015823
- InterPro:   IPR009024 [H]

Pfam domain/function: PF02249 MCR_alpha; PF02745 MCR_alpha_N [H]

EC number: =2.8.4.1 [H]

Molecular weight: Translated: 60869; Mature: 60869

Theoretical pI: Translated: 4.53; Mature: 4.53

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MENEEKVFFKALNQKFKGEDNESNHTSFYCFDGWKQSPRKREFNDAAEKLAKDRNMPFYN
CCCCHHHHHHHHHHHHCCCCCCCCCCEEEEECCCCCCCCCCHHHHHHHHHHHHCCCCCCC
PDIGVPLGQRSLMTYKISGTDDYVEGDDLHFCNNAAIQQLVDDIKRTIIVGMDTAHSVLQ
CCCCCCCCCCCEEEEEECCCCCCCCCCCCEECCHHHHHHHHHHHHHHEEECCCHHHHHHH
ERLGVEVTPETINEYMENINHALPGGAVVQEHMVEVHPGLVSDCYAKIFTGNDELADEID
HHHCCEECHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCHHHHHHHHHCCCCHHHHHHHC
KRVLIDINKEFPEDQAQMLKDYLGNKTYQVSRVPTLVVRACDGGTVSRWSAMQIGMSFIN
CEEEEEECCCCCHHHHHHHHHHHCCCEEEEECCCEEEEEECCCCCCHHHHHHHHHHHHHH
AYKLCAGEAAIADFSYAAKHADVIGMASFLPARRARGPNEPGGVSFGAFSDMIQTSRISD
HHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHCCCC
DPAEVTLEVIAGAAALYDQVWLGSYMSGGVGFTQYASATYTDDILDDFVYYGLDYVEDNY
CHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHCCCCCCHHHHHHHHHHCHHHEECCC
GLCQAEKTMDVVRDISTEVTLYGLEQYEIPTLLETHFGGSQRASVISAAAGCSTAFATAN
CCCCHHHHHHHHHHCCCCEEEEECCCCCCCHHHHHCCCCCHHHHHHHHHHCCCHHEEECC
SNAGVNGWYLSMLLHKEGHSRLGFYGYDLQDQCGSANSLSIRSDEGLIHELRGPNYPNYA
CCCCCCHHHHHHHHHHCCCCCCCEECCCHHHHCCCCCCEEEECCCCHHHHCCCCCCCCHH
MNVGHQPEYAGIAQAPHAARKDAFSVNPLIKIAFADDALSFDFKHPRKEIARGALREFEP
CCCCCCCCCCCCCCCCCHHHCCCCCCCCEEEEEEECCCCCCCCCCHHHHHHHHHHHHCCC
DGERDIIIPAK
CCCCCEEEECC
>Mature Secondary Structure
MENEEKVFFKALNQKFKGEDNESNHTSFYCFDGWKQSPRKREFNDAAEKLAKDRNMPFYN
CCCCHHHHHHHHHHHHCCCCCCCCCCEEEEECCCCCCCCCCHHHHHHHHHHHHCCCCCCC
PDIGVPLGQRSLMTYKISGTDDYVEGDDLHFCNNAAIQQLVDDIKRTIIVGMDTAHSVLQ
CCCCCCCCCCCEEEEEECCCCCCCCCCCCEECCHHHHHHHHHHHHHHEEECCCHHHHHHH
ERLGVEVTPETINEYMENINHALPGGAVVQEHMVEVHPGLVSDCYAKIFTGNDELADEID
HHHCCEECHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCHHHHHHHHHCCCCHHHHHHHC
KRVLIDINKEFPEDQAQMLKDYLGNKTYQVSRVPTLVVRACDGGTVSRWSAMQIGMSFIN
CEEEEEECCCCCHHHHHHHHHHHCCCEEEEECCCEEEEEECCCCCCHHHHHHHHHHHHHH
AYKLCAGEAAIADFSYAAKHADVIGMASFLPARRARGPNEPGGVSFGAFSDMIQTSRISD
HHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHCCCC
DPAEVTLEVIAGAAALYDQVWLGSYMSGGVGFTQYASATYTDDILDDFVYYGLDYVEDNY
CHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHCCCCCCHHHHHHHHHHCHHHEECCC
GLCQAEKTMDVVRDISTEVTLYGLEQYEIPTLLETHFGGSQRASVISAAAGCSTAFATAN
CCCCHHHHHHHHHHCCCCEEEEECCCCCCCHHHHHCCCCCHHHHHHHHHHCCCHHEEECC
SNAGVNGWYLSMLLHKEGHSRLGFYGYDLQDQCGSANSLSIRSDEGLIHELRGPNYPNYA
CCCCCCHHHHHHHHHHCCCCCCCEECCCHHHHCCCCCCEEEECCCCHHHHCCCCCCCCHH
MNVGHQPEYAGIAQAPHAARKDAFSVNPLIKIAFADDALSFDFKHPRKEIARGALREFEP
CCCCCCCCCCCCCCCCCHHHCCCCCCCCEEEEEEECCCCCCCCCCHHHHHHHHHHHHCCC
DGERDIIIPAK
CCCCCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8177216 [H]