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The map label for this gene is yleA [C]

Identifier: 148642905

GI number: 148642905

Start: 801909

End: 803189

Strand: Reverse

Name: yleA [C]

Synonym: Msm_0845

Alternate gene names: 148642905

Gene position: 803189-801909 (Counterclockwise)

Preceding gene: 148642906

Following gene: 148642904

Centisome position: 43.34

GC content: 34.82

Gene sequence:

>1281_bases
ATGAAAGTATATATTGACACATATGGCTGTACATTCAATAAAGCCGACGCTCAGATAATGGGGGGAGTTTTAAAAGAAAA
TCATATTGATTTGGTTGATTCTCCTGAACTGGCAGATGTTATAATTGTAAATACATGTTATGTAAAGCTCCCGACTGAAA
ATAAGGTAGTTTATAAAATTCAGCAGTTGCAGGAAAAATTTCCAGATAAAAAAGTTATCGTAAGCGGGTGCATGGTTGAA
ATTGATCCTGAAAAATTAGAAAAAGTAGCTCCTGACTGCAGCTGGATAGGACCTCATCAACTTAATAAAACAGCAGATGT
AGTTAACGGAACTTATTGTGGCAGGGTTATTCGTGAGTGCGGATTTTCAAAAGACAGTAAAGTTGGGGTTCCTAAAGTTT
CTGATGGTTCTTTAATTCACATAATTCAAATAGCTGAGGGCTGTTTGGGAGCATGTACTTTTTGCTGTACTCGTTTTGCA
AGAGGACCATTAAACAGTTATCCGATTAAGGATATAGTTGCCGAAGCTAAAAAAGCTATTGATGATGGTGCTGTTGAAAT
TCAGCTTACTGCTCAGGACACTGCCGCTTTCGGATATGATAGTGGCGAAAAACTGTCTGATTTAATTAAAGAAGTGGCTA
ATTTGGATGGAGAATTTCGTGTTCGTGTTGGAATGATGCATCCTAAAAACATTTTAAATAATGTTGATGAAATAATTGAT
GCAATTAAACATCCGAAGGTATATAATTTCATTCATTTGCCTGTACAAACAGGAAGCAATAAAGTTTTATCTGAAATGAG
AAGAGGCCATACACTGGATCAGTATCTGGATATTGTTTCAAAATTTAAAAGTGAAATTCCGGATTTGACCTTGGCGGTAG
ATATTATTGTCGGATATCCAACTGAAAGTGATGAAGATTTCCAGTTAACTGTTGATTTACTTAGAAATATAAAACCAAGT
TTGATTCATTTGTCAAAATATCAGCATAGGAAAGGTGCAGTTTCATCTTCTCTTAAGGAAATTCCCCATGAAGTCATGAA
AAAAAGGTCTAGGAATTTGTCTAGAATCAAAACTGAAATTACTGAAGAAGAAAACAAAGAATTAGTTGGTTCTGTTCAAA
ATGCCGTTGTTGTGGAAGTAGGTTCTAAAGGTGGATTTATAGCTAAAACAGATTCTTATATTCCAGTAATTGTTGACGGT
GTTAATTTAGGAGACTTTATTAAGGTTAAAATCACTGATGCAACAGCTACTTACCTTAAGGGTGATGTTGTGTCAAAATA
A

Upstream 100 bases:

>100_bases
AAGTAATTAAAAGAGTTTATGGAAAACCTGTTAAATTCAATAATTTCGATTATGATTTAACCAAATATATTGTTAAGAAA
ACATTAAGCGAGTAAGTTTC

Downstream 100 bases:

>100_bases
TTTTTTATTTTTCTGTTATGGTTTATTTTTCTATCATTGCTTATTTTTGTTCTTCAATTATTAACTTTGTTTTTTAAATT
TTCCAATTTGGAAAATGATA

Product: 2-methylthioadenine synthetase, MiaB

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 426; Mature: 426

Protein sequence:

>426_residues
MKVYIDTYGCTFNKADAQIMGGVLKENHIDLVDSPELADVIIVNTCYVKLPTENKVVYKIQQLQEKFPDKKVIVSGCMVE
IDPEKLEKVAPDCSWIGPHQLNKTADVVNGTYCGRVIRECGFSKDSKVGVPKVSDGSLIHIIQIAEGCLGACTFCCTRFA
RGPLNSYPIKDIVAEAKKAIDDGAVEIQLTAQDTAAFGYDSGEKLSDLIKEVANLDGEFRVRVGMMHPKNILNNVDEIID
AIKHPKVYNFIHLPVQTGSNKVLSEMRRGHTLDQYLDIVSKFKSEIPDLTLAVDIIVGYPTESDEDFQLTVDLLRNIKPS
LIHLSKYQHRKGAVSSSLKEIPHEVMKKRSRNLSRIKTEITEEENKELVGSVQNAVVVEVGSKGGFIAKTDSYIPVIVDG
VNLGDFIKVKITDATATYLKGDVVSK

Sequences:

>Translated_426_residues
MKVYIDTYGCTFNKADAQIMGGVLKENHIDLVDSPELADVIIVNTCYVKLPTENKVVYKIQQLQEKFPDKKVIVSGCMVE
IDPEKLEKVAPDCSWIGPHQLNKTADVVNGTYCGRVIRECGFSKDSKVGVPKVSDGSLIHIIQIAEGCLGACTFCCTRFA
RGPLNSYPIKDIVAEAKKAIDDGAVEIQLTAQDTAAFGYDSGEKLSDLIKEVANLDGEFRVRVGMMHPKNILNNVDEIID
AIKHPKVYNFIHLPVQTGSNKVLSEMRRGHTLDQYLDIVSKFKSEIPDLTLAVDIIVGYPTESDEDFQLTVDLLRNIKPS
LIHLSKYQHRKGAVSSSLKEIPHEVMKKRSRNLSRIKTEITEEENKELVGSVQNAVVVEVGSKGGFIAKTDSYIPVIVDG
VNLGDFIKVKITDATATYLKGDVVSK
>Mature_426_residues
MKVYIDTYGCTFNKADAQIMGGVLKENHIDLVDSPELADVIIVNTCYVKLPTENKVVYKIQQLQEKFPDKKVIVSGCMVE
IDPEKLEKVAPDCSWIGPHQLNKTADVVNGTYCGRVIRECGFSKDSKVGVPKVSDGSLIHIIQIAEGCLGACTFCCTRFA
RGPLNSYPIKDIVAEAKKAIDDGAVEIQLTAQDTAAFGYDSGEKLSDLIKEVANLDGEFRVRVGMMHPKNILNNVDEIID
AIKHPKVYNFIHLPVQTGSNKVLSEMRRGHTLDQYLDIVSKFKSEIPDLTLAVDIIVGYPTESDEDFQLTVDLLRNIKPS
LIHLSKYQHRKGAVSSSLKEIPHEVMKKRSRNLSRIKTEITEEENKELVGSVQNAVVVEVGSKGGFIAKTDSYIPVIVDG
VNLGDFIKVKITDATATYLKGDVVSK

Specific function: Unknown

COG id: COG0621

COG function: function code J; 2-methylthioadenine synthetase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 TRAM domain [H]

Homologues:

Organism=Homo sapiens, GI93277076, Length=435, Percent_Identity=33.3333333333333, Blast_Score=262, Evalue=4e-70,
Organism=Homo sapiens, GI28872784, Length=487, Percent_Identity=27.9260780287474, Blast_Score=164, Evalue=1e-40,
Organism=Homo sapiens, GI28872782, Length=486, Percent_Identity=27.1604938271605, Blast_Score=164, Evalue=1e-40,
Organism=Escherichia coli, GI1786882, Length=441, Percent_Identity=29.2517006802721, Blast_Score=186, Evalue=3e-48,
Organism=Escherichia coli, GI1787057, Length=446, Percent_Identity=28.2511210762332, Blast_Score=153, Evalue=2e-38,
Organism=Caenorhabditis elegans, GI71996771, Length=349, Percent_Identity=32.6647564469914, Blast_Score=201, Evalue=5e-52,
Organism=Caenorhabditis elegans, GI17553146, Length=467, Percent_Identity=26.5524625267666, Blast_Score=147, Evalue=1e-35,
Organism=Drosophila melanogaster, GI19922432, Length=435, Percent_Identity=31.7241379310345, Blast_Score=235, Evalue=4e-62,
Organism=Drosophila melanogaster, GI21356207, Length=491, Percent_Identity=25.8655804480652, Blast_Score=166, Evalue=3e-41,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006638
- InterPro:   IPR005839
- InterPro:   IPR020612
- InterPro:   IPR013848
- InterPro:   IPR006466
- InterPro:   IPR007197
- InterPro:   IPR002792 [H]

Pfam domain/function: PF04055 Radical_SAM; PF01938 TRAM; PF00919 UPF0004 [H]

EC number: NA

Molecular weight: Translated: 47056; Mature: 47056

Theoretical pI: Translated: 6.36; Mature: 6.36

Prosite motif: PS50926 TRAM ; PS01278 UPF0004

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKVYIDTYGCTFNKADAQIMGGVLKENHIDLVDSPELADVIIVNTCYVKLPTENKVVYKI
CEEEEEECCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCEEEEEEEEEEECCCCCHHHHH
QQLQEKFPDKKVIVSGCMVEIDPEKLEKVAPDCSWIGPHQLNKTADVVNGTYCGRVIREC
HHHHHHCCCCEEEEECCEEEECHHHHHHHCCCCCCCCHHHCCCHHHHHCCHHHHHHHHHC
GFSKDSKVGVPKVSDGSLIHIIQIAEGCLGACTFCCTRFARGPLNSYPIKDIVAEAKKAI
CCCCCCCCCCCCCCCCCEEEEEEHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHC
DDGAVEIQLTAQDTAAFGYDSGEKLSDLIKEVANLDGEFRVRVGMMHPKNILNNVDEIID
CCCCEEEEEEECCCCCCCCCCCHHHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHHHHH
AIKHPKVYNFIHLPVQTGSNKVLSEMRRGHTLDQYLDIVSKFKSEIPDLTLAVDIIVGYP
HHCCCCEEEEEEEEEECCCHHHHHHHHCCCCHHHHHHHHHHHHHHCCCEEEEEEEEEECC
TESDEDFQLTVDLLRNIKPSLIHLSKYQHRKGAVSSSLKEIPHEVMKKRSRNLSRIKTEI
CCCCCCCEEEHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHH
TEEENKELVGSVQNAVVVEVGSKGGFIAKTDSYIPVIVDGVNLGDFIKVKITDATATYLK
HHHHHHHHHHHHCCEEEEEECCCCCEEEECCCCCEEEEECCCCCCEEEEEEECCHHHHHC
GDVVSK
CCCCCC
>Mature Secondary Structure
MKVYIDTYGCTFNKADAQIMGGVLKENHIDLVDSPELADVIIVNTCYVKLPTENKVVYKI
CEEEEEECCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCEEEEEEEEEEECCCCCHHHHH
QQLQEKFPDKKVIVSGCMVEIDPEKLEKVAPDCSWIGPHQLNKTADVVNGTYCGRVIREC
HHHHHHCCCCEEEEECCEEEECHHHHHHHCCCCCCCCHHHCCCHHHHHCCHHHHHHHHHC
GFSKDSKVGVPKVSDGSLIHIIQIAEGCLGACTFCCTRFARGPLNSYPIKDIVAEAKKAI
CCCCCCCCCCCCCCCCCEEEEEEHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHC
DDGAVEIQLTAQDTAAFGYDSGEKLSDLIKEVANLDGEFRVRVGMMHPKNILNNVDEIID
CCCCEEEEEEECCCCCCCCCCCHHHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHHHHH
AIKHPKVYNFIHLPVQTGSNKVLSEMRRGHTLDQYLDIVSKFKSEIPDLTLAVDIIVGYP
HHCCCCEEEEEEEEEECCCHHHHHHHHCCCCHHHHHHHHHHHHHHCCCEEEEEEEEEECC
TESDEDFQLTVDLLRNIKPSLIHLSKYQHRKGAVSSSLKEIPHEVMKKRSRNLSRIKTEI
CCCCCCCEEEHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHH
TEEENKELVGSVQNAVVVEVGSKGGFIAKTDSYIPVIVDGVNLGDFIKVKITDATATYLK
HHHHHHHHHHHHCCEEEEEECCCCCEEEECCCCCEEEEECCCCCCEEEEEEECCHHHHHC
GDVVSK
CCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9371463 [H]