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The map label for this gene is aroK

Identifier: 148642895

GI number: 148642895

Start: 792366

End: 793235

Strand: Reverse

Name: aroK

Synonym: Msm_0835

Alternate gene names: 148642895

Gene position: 793235-792366 (Counterclockwise)

Preceding gene: 148642896

Following gene: 148642894

Centisome position: 42.8

GC content: 34.14

Gene sequence:

>870_bases
ATGAAAAAATCAGTAAGGTCTCCAGGTTCAGCAACAGTAATTAATGCAATAGCTACAGGTTTCGGTGCTGCTTTTGGTAT
AGGTTTGGATATAAAATGCTGTGCCAATACTCAAAATAGTTCTATAACCTGCTCTAATGATGTTGGAGCACCAACTACAT
TGATGGAGATTTGTGCTAAAAAAACTTTTGAAAAATATGGAATTTCTTCAGATGATTTTGGAATGAATTTTAAGACAGAA
TCAGAACTGCCGATGGCATCAGGATTATCAAGCAGCAGTGCATTATCTAATGCTGTTGTAAGTATATCTTCCAAAATTAT
TGCAGAAGAATTTAATTTAATGCCTCTTGATGATTTGGAAATAATCAATTTAGCTATTGATGCATCTCTTGAGGCAAAAG
TTACTATAACCGGATCATTTGATGATGCAACAGCTTCATATTTTGGAGGAGTTGTTGTTACAGATAACAAAAATAGAAAA
TTCATCATCAAAGAGAAAATGGAAGAATATCCTGTTTTGGTTTATATGCCTAATTTTGGTTCTAAATCCGGAAGTTCTGA
TGTTGGCCGTATGAAAGTGCTGTCACCACTTGTTGAAACAGCTTTCGGATTGGCCAGATCAGGAGATTATTTTAAAGCAC
TTAATTTAAATGGTTTAATTTATGCAAACACTTTAGGTTTTGATTCCAATATAGCTATTGATGCTTTGGAAGTTGGTGCA
ATAGCTTCAGGTTTATCTGGAACTGGATCATCATTTGTAGCTATATGTGAGGATGAAGCAATTGATGATATTAAGGAAAC
TTGGTCCAAATATGAAGGAAGGGTTATTGAAACAAAAGTTGATAACATCGGGTGTCAGTTTATAGGATAA

Upstream 100 bases:

>100_bases
TGATTTTGGATGATGAATTTAGAAGTAATTTAGCTTCAAATGCAAGAAACAGGGCTAAAATATTCAGTAAAGTTGAAATT
CCTTATGATGAGGTAAAATA

Downstream 100 bases:

>100_bases
TAATTTTATGTATGACCAAAATAAATTTTTATTAGAAACGTCAAATAATCCATAGTATTAAATAGTATAATACTAATAAA
TTATATTATTATCATTATTA

Product: shikimate kinase

Products: NA

Alternate protein names: SK

Number of amino acids: Translated: 289; Mature: 289

Protein sequence:

>289_residues
MKKSVRSPGSATVINAIATGFGAAFGIGLDIKCCANTQNSSITCSNDVGAPTTLMEICAKKTFEKYGISSDDFGMNFKTE
SELPMASGLSSSSALSNAVVSISSKIIAEEFNLMPLDDLEIINLAIDASLEAKVTITGSFDDATASYFGGVVVTDNKNRK
FIIKEKMEEYPVLVYMPNFGSKSGSSDVGRMKVLSPLVETAFGLARSGDYFKALNLNGLIYANTLGFDSNIAIDALEVGA
IASGLSGTGSSFVAICEDEAIDDIKETWSKYEGRVIETKVDNIGCQFIG

Sequences:

>Translated_289_residues
MKKSVRSPGSATVINAIATGFGAAFGIGLDIKCCANTQNSSITCSNDVGAPTTLMEICAKKTFEKYGISSDDFGMNFKTE
SELPMASGLSSSSALSNAVVSISSKIIAEEFNLMPLDDLEIINLAIDASLEAKVTITGSFDDATASYFGGVVVTDNKNRK
FIIKEKMEEYPVLVYMPNFGSKSGSSDVGRMKVLSPLVETAFGLARSGDYFKALNLNGLIYANTLGFDSNIAIDALEVGA
IASGLSGTGSSFVAICEDEAIDDIKETWSKYEGRVIETKVDNIGCQFIG
>Mature_289_residues
MKKSVRSPGSATVINAIATGFGAAFGIGLDIKCCANTQNSSITCSNDVGAPTTLMEICAKKTFEKYGISSDDFGMNFKTE
SELPMASGLSSSSALSNAVVSISSKIIAEEFNLMPLDDLEIINLAIDASLEAKVTITGSFDDATASYFGGVVVTDNKNRK
FIIKEKMEEYPVLVYMPNFGSKSGSSDVGRMKVLSPLVETAFGLARSGDYFKALNLNGLIYANTLGFDSNIAIDALEVGA
IASGLSGTGSSFVAICEDEAIDDIKETWSKYEGRVIETKVDNIGCQFIG

Specific function: Unknown

COG id: COG1685

COG function: function code EH; Archaeal shikimate kinase

Gene ontology:

Cell location: Cytoplasm (Probable)

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GHMP kinase family. Archaeal shikimate kinase subfamily

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): AROK_METS3 (A5ULG2)

Other databases:

- EMBL:   CP000678
- RefSeq:   YP_001273408.1
- ProteinModelPortal:   A5ULG2
- STRING:   A5ULG2
- GeneID:   5217264
- GenomeReviews:   CP000678_GR
- KEGG:   msi:Msm_0835
- eggNOG:   arNOG05254
- HOGENOM:   HBG646614
- OMA:   AFDDACA
- ProtClustDB:   PRK01123
- GO:   GO:0005737
- HAMAP:   MF_00370
- InterPro:   IPR006204
- InterPro:   IPR006203
- InterPro:   IPR020568
- InterPro:   IPR014721
- InterPro:   IPR010189
- Gene3D:   G3DSA:3.30.230.10
- PIRSF:   PIRSF005758
- TIGRFAMs:   TIGR01920

Pfam domain/function: PF00288 GHMP_kinases_N; SSF54211 Ribosomal_S5_D2-typ_fold

EC number: =2.7.1.71

Molecular weight: Translated: 30581; Mature: 30581

Theoretical pI: Translated: 4.31; Mature: 4.31

Prosite motif: PS00627 GHMP_KINASES_ATP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKSVRSPGSATVINAIATGFGAAFGIGLDIKCCANTQNSSITCSNDVGAPTTLMEICAK
CCCCCCCCCCHHHHHHHHHHHHHHEECCEEEEEECCCCCCEEEECCCCCCHHHHHHHHHH
KTFEKYGISSDDFGMNFKTESELPMASGLSSSSALSNAVVSISSKIIAEEFNLMPLDDLE
HHHHHHCCCCCCCCCCCCCCCCCCHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCE
IINLAIDASLEAKVTITGSFDDATASYFGGVVVTDNKNRKFIIKEKMEEYPVLVYMPNFG
EEEEEECCCCEEEEEEEECCCCHHHHHHCCEEEECCCCCEEEEEEHHHHCCEEEEECCCC
SKSGSSDVGRMKVLSPLVETAFGLARSGDYFKALNLNGLIYANTLGFDSNIAIDALEVGA
CCCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCEEEEEECCCCCCCEEEHEEHHH
IASGLSGTGSSFVAICEDEAIDDIKETWSKYEGRVIETKVDNIGCQFIG
HHCCCCCCCCCEEEEECCHHHHHHHHHHHHHCCEEEEEEECCCCEEECC
>Mature Secondary Structure
MKKSVRSPGSATVINAIATGFGAAFGIGLDIKCCANTQNSSITCSNDVGAPTTLMEICAK
CCCCCCCCCCHHHHHHHHHHHHHHEECCEEEEEECCCCCCEEEECCCCCCHHHHHHHHHH
KTFEKYGISSDDFGMNFKTESELPMASGLSSSSALSNAVVSISSKIIAEEFNLMPLDDLE
HHHHHHCCCCCCCCCCCCCCCCCCHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCE
IINLAIDASLEAKVTITGSFDDATASYFGGVVVTDNKNRKFIIKEKMEEYPVLVYMPNFG
EEEEEECCCCEEEEEEEECCCCHHHHHHCCEEEECCCCCEEEEEEHHHHCCEEEEECCCC
SKSGSSDVGRMKVLSPLVETAFGLARSGDYFKALNLNGLIYANTLGFDSNIAIDALEVGA
CCCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCEEEEEECCCCCCCEEEHEEHHH
IASGLSGTGSSFVAICEDEAIDDIKETWSKYEGRVIETKVDNIGCQFIG
HHCCCCCCCCCEEEEECCHHHHHHHHHHHHHCCEEEEEEECCCCEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA