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The map label for this gene is ttdB [H]

Identifier: 148642829

GI number: 148642829

Start: 728635

End: 729156

Strand: Reverse

Name: ttdB [H]

Synonym: Msm_0769

Alternate gene names: 148642829

Gene position: 729156-728635 (Counterclockwise)

Preceding gene: 148642830

Following gene: 148642828

Centisome position: 39.35

GC content: 36.21

Gene sequence:

>522_bases
ATGGAAAAAAATATTAAAGTGCCGGTTAAAAACGAAGATTTAACTGACTTAAAAATTGGAGATGTAATTACATTAACTGG
AAATATTATCACTGCAAGAGACCAAGCACATAAAAGAATTCTGGAACAGGGTGCTCCGTTGGATATTGAAGGTGCAGCAA
TATTTCATGCAGGACCAATTATATCTGAAGATGAAAACGGATATAAAATGGTAGCTGTAGGTCCAACCACTTCCATGAGA
ATGAATCCTTATCAAAGTGATGTTATTGATATGGGGCCTAAAATAGTAATAGGTAAGGGAGGAATGGATGATACAGTAAG
GAAAGCTTTAGTTAAAAACAATGCATTGTATGTTGTAGCTACTGGTGGATGTGCAGCACTTTATGTTGATGCAGTTGAAG
AAATTGAAAGTGTTGACTGGCTGGATTTAGGAATGCCGGAAGCTATGTGGAATTTGAAAGTTAAAGATTTTGGACCGCTT
ATAGTAGCTATGGATAGTGAAGGCAACAGTTTATATGACTGA

Upstream 100 bases:

>100_bases
TTTAAATCACCAAAGTTTTGAAAAGAGCATTGGTGTCTACCCATTAAATTTATAAAAGCTAAAAATTTTATATATTTATA
ATAATTTACAAGGTGACCAA

Downstream 100 bases:

>100_bases
TTTTTAAATCAAATAAGAATGCTTATATAATATGTGAATTTTAACTATAATTTAGATTATATATAAATAAAGTTTCAGGA
TGTGTTATAAATGCCAGATA

Product: fumarate hydratase, class I

Products: NA

Alternate protein names: L-TTD beta [H]

Number of amino acids: Translated: 173; Mature: 173

Protein sequence:

>173_residues
MEKNIKVPVKNEDLTDLKIGDVITLTGNIITARDQAHKRILEQGAPLDIEGAAIFHAGPIISEDENGYKMVAVGPTTSMR
MNPYQSDVIDMGPKIVIGKGGMDDTVRKALVKNNALYVVATGGCAALYVDAVEEIESVDWLDLGMPEAMWNLKVKDFGPL
IVAMDSEGNSLYD

Sequences:

>Translated_173_residues
MEKNIKVPVKNEDLTDLKIGDVITLTGNIITARDQAHKRILEQGAPLDIEGAAIFHAGPIISEDENGYKMVAVGPTTSMR
MNPYQSDVIDMGPKIVIGKGGMDDTVRKALVKNNALYVVATGGCAALYVDAVEEIESVDWLDLGMPEAMWNLKVKDFGPL
IVAMDSEGNSLYD
>Mature_173_residues
MEKNIKVPVKNEDLTDLKIGDVITLTGNIITARDQAHKRILEQGAPLDIEGAAIFHAGPIISEDENGYKMVAVGPTTSMR
MNPYQSDVIDMGPKIVIGKGGMDDTVRKALVKNNALYVVATGGCAALYVDAVEEIESVDWLDLGMPEAMWNLKVKDFGPL
IVAMDSEGNSLYD

Specific function: Unknown

COG id: COG1838

COG function: function code C; Tartrate dehydratase beta subunit/Fumarate hydratase class I, C-terminal domain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I fumarase family [H]

Homologues:

Organism=Escherichia coli, GI1789443, Length=174, Percent_Identity=48.8505747126437, Blast_Score=184, Evalue=3e-48,
Organism=Escherichia coli, GI1787897, Length=168, Percent_Identity=31.547619047619, Blast_Score=85, Evalue=2e-18,
Organism=Escherichia coli, GI1790564, Length=169, Percent_Identity=32.5443786982249, Blast_Score=82, Evalue=2e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004647 [H]

Pfam domain/function: PF05683 Fumerase_C [H]

EC number: =4.2.1.32 [H]

Molecular weight: Translated: 18737; Mature: 18737

Theoretical pI: Translated: 4.30; Mature: 4.30

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
5.2 %Met     (Translated Protein)
5.8 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
5.2 %Met     (Mature Protein)
5.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEKNIKVPVKNEDLTDLKIGDVITLTGNIITARDQAHKRILEQGAPLDIEGAAIFHAGPI
CCCCCCCEECCCCCCCEEECCEEEEECCEEEECHHHHHHHHHCCCCCCCCCEEEEECCCE
ISEDENGYKMVAVGPTTSMRMNPYQSDVIDMGPKIVIGKGGMDDTVRKALVKNNALYVVA
ECCCCCCEEEEEECCCCCEEECCCCCHHHHCCCEEEEECCCCCHHHHHHHHCCCCEEEEE
TGGCAALYVDAVEEIESVDWLDLGMPEAMWNLKVKDFGPLIVAMDSEGNSLYD
CCCCEEEHHHHHHHHHCCCEECCCCCCHHEEEEECCCCCEEEEEECCCCCCCC
>Mature Secondary Structure
MEKNIKVPVKNEDLTDLKIGDVITLTGNIITARDQAHKRILEQGAPLDIEGAAIFHAGPI
CCCCCCCEECCCCCCCEEECCEEEEECCEEEECHHHHHHHHHCCCCCCCCCEEEEECCCE
ISEDENGYKMVAVGPTTSMRMNPYQSDVIDMGPKIVIGKGGMDDTVRKALVKNNALYVVA
ECCCCCCEEEEEECCCCCEEECCCCCHHHHCCCEEEEECCCCCHHHHHHHHCCCCEEEEE
TGGCAALYVDAVEEIESVDWLDLGMPEAMWNLKVKDFGPLIVAMDSEGNSLYD
CCCCEEEHHHHHHHHHCCCEECCCCCCHHEEEEECCCCCEEEEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]