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The map label for this gene is nudG [H]

Identifier: 148642751

GI number: 148642751

Start: 664103

End: 664489

Strand: Reverse

Name: nudG [H]

Synonym: Msm_0691

Alternate gene names: 148642751

Gene position: 664489-664103 (Counterclockwise)

Preceding gene: 148642752

Following gene: 148642750

Centisome position: 35.86

GC content: 31.27

Gene sequence:

>387_bases
ATGAAAGAAATAAAAGTAGTGGCAGCTATTATTCAAAAAGAAAACAAAATTTTAGCTACTAAAAGAGGATATGGCGAGTT
TATAAACATGTGGGAGTTTCCGGGAGGAAAAATCGAATCAGGTGAAACCAAAGAGCAGGCCCTAGTTCGTGAAATTAAAG
AAGAATTAAACATTGAAATTAGTGTTGATAAATTTGCCATAGATATTGAGTATCAGTATCCTAACTTTTATTTATTCATG
TCCTGTTTTATGTGTTCAATTAAGGAAGGTTCAATCGAACTTTTAGAGCATAATGATGGTAAATGGATTACAAAAGAAGA
ATTAAACACTTTAAATTGGCTTCCGGCAGATATTGATGCAGTTAATTATCTAAAAGAAAACATGTGA

Upstream 100 bases:

>100_bases
TTCATTGAAAAATTAAGACTTATATTATTAAAATTAAATGAAGATGATAGAATTATTAAAAAATTAGGGGAATTGGACAT
TTAATTCAGGTGTAAAAAAC

Downstream 100 bases:

>100_bases
TTTTTATGGATAATCAGAATGATATTTTAGAGGGAGCTAAAACTGCTTTTATCAATGAAACTTATAATCCTGCAAATGAT
TTCAAACCTAAATTCCTTTC

Product: mutator mutT protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 128; Mature: 128

Protein sequence:

>128_residues
MKEIKVVAAIIQKENKILATKRGYGEFINMWEFPGGKIESGETKEQALVREIKEELNIEISVDKFAIDIEYQYPNFYLFM
SCFMCSIKEGSIELLEHNDGKWITKEELNTLNWLPADIDAVNYLKENM

Sequences:

>Translated_128_residues
MKEIKVVAAIIQKENKILATKRGYGEFINMWEFPGGKIESGETKEQALVREIKEELNIEISVDKFAIDIEYQYPNFYLFM
SCFMCSIKEGSIELLEHNDGKWITKEELNTLNWLPADIDAVNYLKENM
>Mature_128_residues
MKEIKVVAAIIQKENKILATKRGYGEFINMWEFPGGKIESGETKEQALVREIKEELNIEISVDKFAIDIEYQYPNFYLFM
SCFMCSIKEGSIELLEHNDGKWITKEELNTLNWLPADIDAVNYLKENM

Specific function: Specific for pyrimidine substrates. Acts on 5-methyl- dCTP, CTP and dCTP in decreasing order [H]

COG id: COG0494

COG function: function code LR; NTP pyrophosphohydrolases including oxidative damage repair enzymes

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 nudix hydrolase domain [H]

Homologues:

Organism=Escherichia coli, GI1788056, Length=119, Percent_Identity=36.1344537815126, Blast_Score=80, Evalue=4e-17,
Organism=Escherichia coli, GI1786288, Length=127, Percent_Identity=34.6456692913386, Blast_Score=71, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020476
- InterPro:   IPR020084
- InterPro:   IPR000086
- InterPro:   IPR015797 [H]

Pfam domain/function: PF00293 NUDIX [H]

EC number: 3.6.1.-

Molecular weight: Translated: 14917; Mature: 14917

Theoretical pI: Translated: 4.43; Mature: 4.43

Prosite motif: PS00893 NUDIX

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
5.5 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
5.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKEIKVVAAIIQKENKILATKRGYGEFINMWEFPGGKIESGETKEQALVREIKEELNIEI
CCHHHHHHHHHHCCCCEEEECCCCHHHHEHCCCCCCCCCCCCCHHHHHHHHHHHHCCEEE
SVDKFAIDIEYQYPNFYLFMSCFMCSIKEGSIELLEHNDGKWITKEELNTLNWLPADIDA
EEEEEEEEEEEECCCHHHHHHHHHHHCCCCCEEEEEECCCCEEEHHHCCCCCCCCCCHHH
VNYLKENM
HHHHHHCC
>Mature Secondary Structure
MKEIKVVAAIIQKENKILATKRGYGEFINMWEFPGGKIESGETKEQALVREIKEELNIEI
CCHHHHHHHHHHCCCCEEEECCCCHHHHEHCCCCCCCCCCCCCHHHHHHHHHHHHCCEEE
SVDKFAIDIEYQYPNFYLFMSCFMCSIKEGSIELLEHNDGKWITKEELNTLNWLPADIDA
EEEEEEEEEEEECCCHHHHHHHHHHHCCCCCEEEEEECCCCEEEHHHCCCCCCCCCCHHH
VNYLKENM
HHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: Fe; Mn [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9097039; 9278503; 11053429 [H]