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The map label for this gene is yxeQ [H]

Identifier: 148642509

GI number: 148642509

Start: 427167

End: 428564

Strand: Reverse

Name: yxeQ [H]

Synonym: Msm_0449

Alternate gene names: 148642509

Gene position: 428564-427167 (Counterclockwise)

Preceding gene: 148642510

Following gene: 148642508

Centisome position: 23.13

GC content: 32.55

Gene sequence:

>1398_bases
ATGTTTTTACAAAATATTTCCAAATTTATTTCAAACTATCGTTATGAACAGGCATCAAAAGAAACCCTTAATGTGGTAAA
AGCAGCATTTATTGATTTTTTTGGAGTCACATATAGGGGAGTAAATGAAGAATCTTCTAGAATAGCTTTCAATACGATTA
GTGAACTATTTTTTGGAAATATGGAGTTTGAGCTGGAATCTTCTGTTATTGGTATGCCCAATTTTAAAACAAATCTGCTG
AATGCAGGTTTTTTAAATGGTATTTCAGCTCATGTTTTGGAATTGGATGATGGTCATAGAGGCGCACAAATTCATTTGGG
TGCAGTTATTTTCCCAACTGCCTTGGCTATTAGTGAAGCTTATGATTTGGACGGCAAATCTTTTTTAGAAGCGGTTATTG
CAGGTTATGAAGTCGGAATAATGCTGGGCCAAATTGTCAATCCTCAACATAGAAACAATGGATTTCATACAACAGGAACT
GTCGGAACATTTGTTGCAGGTGCTGTTGCTTCTAAATTGCTTAATCTTGATGAAAACCAAACATTAAATGCTTTAGGTTT
GTGTGGAACTCAGGCTGCAGGTCTTTTAGAGTCTGACCATAATGGGAGTATGGGCAAAGTTCTTCATGTTGGAAAAGCTG
TTTATAATGGATTAATATCTGCATTTTTGGCTTTAAACGGATTCACTGGTGCCGGAACAATTTTTGATGGGGATGAAGGT
TTTTTAAAAACAATGGTTTTGTCAGATAGTGATTTTTCTTTAGATGTTGCTCTAAAAAATATGGGTAAAGTTAGGGTCAG
GGACATTTACTTTAAAAAATATCCGTTTTGCAGACATTTGCACTCTTCAATAGATACTGTTTTAAAACTAAAGGCAAGTA
TAGGTGAAGAGTATGAGCATATTGGAAATGTGATTATCAAAACATATGATGTAGCTGCTAAACATGATAATTATAATCCG
AAAAATGTCGAAGAATTAAAACAGAGTTTGCCTTATGCAGTGGCCATTATGCTTGTTTGTGGTGAAATTGATTTGGATGA
TTTAAATCAGTTAATTGAATTTGGCCTGCTTGATAGCTATTCAACAGTTGATAAAGTTAACAGTATTAAGAATCTGGCCA
GTAAAATAATCATTGTTTCTGATAGTGGATTGGATGAGCTATATCCAAATAAAAGACCATCAAATGTTATTATTAAGTTG
GATGAATCTTTCAGAGGGGGAATTTTCCAAAATATTACATTATTGCCAAAAGGTGATTTTGAAAATCCATATCAATTAAA
AGATTTAATTGACAAATTCAAAAGTTTGAATCCTGATTTTGATTTAAATAAATTGCTTGTTGTTGATAATATTGAAGATT
ATTCTATAAAACAACTTATGGAAACATTAAATGAGTAG

Upstream 100 bases:

>100_bases
ATAGTTTTAGTTCTAAGCGGTACACCTTGGTGTTAATTTTTAACACCATTTAAGTTAACTATTTAAGACTATTTTTACAA
TTTAATTATTAAGGTGTTTT

Downstream 100 bases:

>100_bases
ATACTATGAAAAAAACTGAAGAATTCTTGGAACAGCTTGGAATTAAAAGAGCTTATGGCGATTTTGAATCATTTAAACGT
TTTAATGATGGAGGACAGTA

Product: 2-methylcitrate dehydratase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 465; Mature: 465

Protein sequence:

>465_residues
MFLQNISKFISNYRYEQASKETLNVVKAAFIDFFGVTYRGVNEESSRIAFNTISELFFGNMEFELESSVIGMPNFKTNLL
NAGFLNGISAHVLELDDGHRGAQIHLGAVIFPTALAISEAYDLDGKSFLEAVIAGYEVGIMLGQIVNPQHRNNGFHTTGT
VGTFVAGAVASKLLNLDENQTLNALGLCGTQAAGLLESDHNGSMGKVLHVGKAVYNGLISAFLALNGFTGAGTIFDGDEG
FLKTMVLSDSDFSLDVALKNMGKVRVRDIYFKKYPFCRHLHSSIDTVLKLKASIGEEYEHIGNVIIKTYDVAAKHDNYNP
KNVEELKQSLPYAVAIMLVCGEIDLDDLNQLIEFGLLDSYSTVDKVNSIKNLASKIIIVSDSGLDELYPNKRPSNVIIKL
DESFRGGIFQNITLLPKGDFENPYQLKDLIDKFKSLNPDFDLNKLLVVDNIEDYSIKQLMETLNE

Sequences:

>Translated_465_residues
MFLQNISKFISNYRYEQASKETLNVVKAAFIDFFGVTYRGVNEESSRIAFNTISELFFGNMEFELESSVIGMPNFKTNLL
NAGFLNGISAHVLELDDGHRGAQIHLGAVIFPTALAISEAYDLDGKSFLEAVIAGYEVGIMLGQIVNPQHRNNGFHTTGT
VGTFVAGAVASKLLNLDENQTLNALGLCGTQAAGLLESDHNGSMGKVLHVGKAVYNGLISAFLALNGFTGAGTIFDGDEG
FLKTMVLSDSDFSLDVALKNMGKVRVRDIYFKKYPFCRHLHSSIDTVLKLKASIGEEYEHIGNVIIKTYDVAAKHDNYNP
KNVEELKQSLPYAVAIMLVCGEIDLDDLNQLIEFGLLDSYSTVDKVNSIKNLASKIIIVSDSGLDELYPNKRPSNVIIKL
DESFRGGIFQNITLLPKGDFENPYQLKDLIDKFKSLNPDFDLNKLLVVDNIEDYSIKQLMETLNE
>Mature_465_residues
MFLQNISKFISNYRYEQASKETLNVVKAAFIDFFGVTYRGVNEESSRIAFNTISELFFGNMEFELESSVIGMPNFKTNLL
NAGFLNGISAHVLELDDGHRGAQIHLGAVIFPTALAISEAYDLDGKSFLEAVIAGYEVGIMLGQIVNPQHRNNGFHTTGT
VGTFVAGAVASKLLNLDENQTLNALGLCGTQAAGLLESDHNGSMGKVLHVGKAVYNGLISAFLALNGFTGAGTIFDGDEG
FLKTMVLSDSDFSLDVALKNMGKVRVRDIYFKKYPFCRHLHSSIDTVLKLKASIGEEYEHIGNVIIKTYDVAAKHDNYNP
KNVEELKQSLPYAVAIMLVCGEIDLDDLNQLIEFGLLDSYSTVDKVNSIKNLASKIIIVSDSGLDELYPNKRPSNVIIKL
DESFRGGIFQNITLLPKGDFENPYQLKDLIDKFKSLNPDFDLNKLLVVDNIEDYSIKQLMETLNE

Specific function: Unknown

COG id: COG2079

COG function: function code R; Uncharacterized protein involved in propionate catabolism

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the prpD family [H]

Homologues:

Organism=Homo sapiens, GI310129732, Length=458, Percent_Identity=23.7991266375546, Blast_Score=96, Evalue=6e-20,
Organism=Homo sapiens, GI310110533, Length=458, Percent_Identity=23.7991266375546, Blast_Score=96, Evalue=6e-20,
Organism=Homo sapiens, GI310123058, Length=473, Percent_Identity=22.6215644820296, Blast_Score=94, Evalue=2e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005656 [H]

Pfam domain/function: PF03972 MmgE_PrpD [H]

EC number: NA

Molecular weight: Translated: 51303; Mature: 51303

Theoretical pI: Translated: 4.80; Mature: 4.80

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFLQNISKFISNYRYEQASKETLNVVKAAFIDFFGVTYRGVNEESSRIAFNTISELFFGN
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCEEHHHHHHHHHHCC
MEFELESSVIGMPNFKTNLLNAGFLNGISAHVLELDDGHRGAQIHLGAVIFPTALAISEA
CEEEECCCEECCCCCHHHHCCCHHHCCCCEEEEEECCCCCCCEEEECHHHHHHHHHHHHH
YDLDGKSFLEAVIAGYEVGIMLGQIVNPQHRNNGFHTTGTVGTFVAGAVASKLLNLDENQ
CCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCC
TLNALGLCGTQAAGLLESDHNGSMGKVLHVGKAVYNGLISAFLALNGFTGAGTIFDGDEG
CCHHHCCCCCHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEECCCC
FLKTMVLSDSDFSLDVALKNMGKVRVRDIYFKKYPFCRHLHSSIDTVLKLKASIGEEYEH
CEEEEEECCCCCEEEEEHHCCCCEEEEHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHH
IGNVIIKTYDVAAKHDNYNPKNVEELKQSLPYAVAIMLVCGEIDLDDLNQLIEFGLLDSY
HCHHHEEEEEEEECCCCCCCCCHHHHHHHCCHHHHHHHHHCCCCHHHHHHHHHHHCCCCH
STVDKVNSIKNLASKIIIVSDSGLDELYPNKRPSNVIIKLDESFRGGIFQNITLLPKGDF
HHHHHHHHHHHHHHEEEEEECCCCHHHCCCCCCCCEEEEECCCCCCCCHHCEEEEECCCC
ENPYQLKDLIDKFKSLNPDFDLNKLLVVDNIEDYSIKQLMETLNE
CCCHHHHHHHHHHHCCCCCCCCCCEEEEECCCCHHHHHHHHHHCC
>Mature Secondary Structure
MFLQNISKFISNYRYEQASKETLNVVKAAFIDFFGVTYRGVNEESSRIAFNTISELFFGN
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCEEHHHHHHHHHHCC
MEFELESSVIGMPNFKTNLLNAGFLNGISAHVLELDDGHRGAQIHLGAVIFPTALAISEA
CEEEECCCEECCCCCHHHHCCCHHHCCCCEEEEEECCCCCCCEEEECHHHHHHHHHHHHH
YDLDGKSFLEAVIAGYEVGIMLGQIVNPQHRNNGFHTTGTVGTFVAGAVASKLLNLDENQ
CCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCC
TLNALGLCGTQAAGLLESDHNGSMGKVLHVGKAVYNGLISAFLALNGFTGAGTIFDGDEG
CCHHHCCCCCHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEECCCC
FLKTMVLSDSDFSLDVALKNMGKVRVRDIYFKKYPFCRHLHSSIDTVLKLKASIGEEYEH
CEEEEEECCCCCEEEEEHHCCCCEEEEHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHH
IGNVIIKTYDVAAKHDNYNPKNVEELKQSLPYAVAIMLVCGEIDLDDLNQLIEFGLLDSY
HCHHHEEEEEEEECCCCCCCCCHHHHHHHCCHHHHHHHHHCCCCHHHHHHHHHHHCCCCH
STVDKVNSIKNLASKIIIVSDSGLDELYPNKRPSNVIIKLDESFRGGIFQNITLLPKGDF
HHHHHHHHHHHHHHEEEEEECCCCHHHCCCCCCCCEEEEECCCCCCCCHHCEEEEECCCC
ENPYQLKDLIDKFKSLNPDFDLNKLLVVDNIEDYSIKQLMETLNE
CCCHHHHHHHHHHHCCCCCCCCCCEEEEECCCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8867804; 9384377 [H]