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The map label for this gene is ctsA [H]

Identifier: 148642506

GI number: 148642506

Start: 424529

End: 425335

Strand: Reverse

Name: ctsA [H]

Synonym: Msm_0446

Alternate gene names: 148642506

Gene position: 425335-424529 (Counterclockwise)

Preceding gene: 148642507

Following gene: 148642505

Centisome position: 22.95

GC content: 34.82

Gene sequence:

>807_bases
ATGTCGGAAAATAATTTTAAAATTAACGAGCATTCACTAAGAACAGCTATTTCTAAAGTGGAACCTGATAAAATTGTTAC
TAGGGGATACAATCAAAGAGATTTAATTGAAAAAATTAGATATAGTGATATGGTTTTTCTTCTTCTGAAAGGGAGATTGC
CTTCAATAAAAGAGGGAAAATTATTTAATCATGTTTTAGTTTCTTTTTGTGATCACGGAGCCACTCCTCCAAGTACACAA
ACAGCAAGACTTGTTGCCTCTTCAGGTTCTCCGTTAAATGCTGCTGTAGCTGGTGCGCTATTGTCATTTGGACATAAACA
TGCAGGAGCTATTGAAAAAACCATGGAATTATACCAGTCCAAGATTGACTCTTTAATGTTAACCGGAGATGCAGATATTG
ACAATAAACAGATAGCTAGTTTGGCTATTGATTTATACAATGAATATATTGTCTCTAAAAATACTAAAATTCCTGGTTTT
GGACACAGATATCATAATGCTGATCCAAGAGCAGATAAATTAATGGAACTTGTTATAAAAGAAGGATGTGTTGGCCCCCA
TACTAAATTGGCATTGGCCATTGAAGATTTGCTTTATCAAAAGAAAAACATTCGTTTAAATGTTGACGGGGCAAATGCAG
CAATTTTGTCTGATTTAGGTTTTGACCCAAAATTAGGATTGGGGGTATTTATTATTGGCCGTGTTCCGGGCATTATTGCT
CATATTCATGAAGAAACTATTGATGAAGATGAATTTAGACGTTTTTGTGACATTGACGACATTGTTTATGACGGTCCTGG
AAGGTAG

Upstream 100 bases:

>100_bases
TCAGTCAGACCTTCCTGTTTTGTAGAACCGAGAGTTGCAACATTACATTTATAATGGATTATAATTATATTTTAATTATT
AAATTGAGGAAATTAAAACA

Downstream 100 bases:

>100_bases
ATAATATGGATTTTGATGATGTAATTAATAAAAGGTATAGTGTAAGAGGATATTTGGACAAGGAAGTTGAAGATGAAAAA
CTTGAATATGTATTGAAAGC

Product: citrate synthase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 268; Mature: 267

Protein sequence:

>268_residues
MSENNFKINEHSLRTAISKVEPDKIVTRGYNQRDLIEKIRYSDMVFLLLKGRLPSIKEGKLFNHVLVSFCDHGATPPSTQ
TARLVASSGSPLNAAVAGALLSFGHKHAGAIEKTMELYQSKIDSLMLTGDADIDNKQIASLAIDLYNEYIVSKNTKIPGF
GHRYHNADPRADKLMELVIKEGCVGPHTKLALAIEDLLYQKKNIRLNVDGANAAILSDLGFDPKLGLGVFIIGRVPGIIA
HIHEETIDEDEFRRFCDIDDIVYDGPGR

Sequences:

>Translated_268_residues
MSENNFKINEHSLRTAISKVEPDKIVTRGYNQRDLIEKIRYSDMVFLLLKGRLPSIKEGKLFNHVLVSFCDHGATPPSTQ
TARLVASSGSPLNAAVAGALLSFGHKHAGAIEKTMELYQSKIDSLMLTGDADIDNKQIASLAIDLYNEYIVSKNTKIPGF
GHRYHNADPRADKLMELVIKEGCVGPHTKLALAIEDLLYQKKNIRLNVDGANAAILSDLGFDPKLGLGVFIIGRVPGIIA
HIHEETIDEDEFRRFCDIDDIVYDGPGR
>Mature_267_residues
SENNFKINEHSLRTAISKVEPDKIVTRGYNQRDLIEKIRYSDMVFLLLKGRLPSIKEGKLFNHVLVSFCDHGATPPSTQT
ARLVASSGSPLNAAVAGALLSFGHKHAGAIEKTMELYQSKIDSLMLTGDADIDNKQIASLAIDLYNEYIVSKNTKIPGFG
HRYHNADPRADKLMELVIKEGCVGPHTKLALAIEDLLYQKKNIRLNVDGANAAILSDLGFDPKLGLGVFIIGRVPGIIAH
IHEETIDEDEFRRFCDIDDIVYDGPGR

Specific function: Catalyzes The Synthesis Of 2-Methylcitrate From Propionyl-CoA And Oxaloacetate. Also Catalyzes The Condensation Of Oxaloacetate With Acetyl-CoA But With A Lower Specificity. [C]

COG id: COG0372

COG function: function code C; Citrate synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the citrate synthase family [H]

Homologues:

Organism=Escherichia coli, GI1786527, Length=211, Percent_Identity=28.436018957346, Blast_Score=65, Evalue=7e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016142
- InterPro:   IPR016143
- InterPro:   IPR002020
- InterPro:   IPR016141
- InterPro:   IPR019810 [H]

Pfam domain/function: PF00285 Citrate_synt [H]

EC number: =2.3.3.1 [H]

Molecular weight: Translated: 29624; Mature: 29493

Theoretical pI: Translated: 6.68; Mature: 6.68

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSENNFKINEHSLRTAISKVEPDKIVTRGYNQRDLIEKIRYSDMVFLLLKGRLPSIKEGK
CCCCCCEECHHHHHHHHHHCCCHHHHHCCCCHHHHHHHHHHHHEEEEEECCCCCCCCCCH
LFNHVLVSFCDHGATPPSTQTARLVASSGSPLNAAVAGALLSFGHKHAGAIEKTMELYQS
HHHHHHHHHHHCCCCCCCCCHHEEEECCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHH
KIDSLMLTGDADIDNKQIASLAIDLYNEYIVSKNTKIPGFGHRYHNADPRADKLMELVIK
HHHHEEEECCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHH
EGCVGPHTKLALAIEDLLYQKKNIRLNVDGANAAILSDLGFDPKLGLGVFIIGRVPGIIA
HCCCCCCHHHHHHHHHHHHHHCCCEEEECCCCCHHHHHCCCCCCCCCCEEEECHHHHHHH
HIHEETIDEDEFRRFCDIDDIVYDGPGR
HHHHHCCCHHHHHHHCCHHHEEECCCCC
>Mature Secondary Structure 
SENNFKINEHSLRTAISKVEPDKIVTRGYNQRDLIEKIRYSDMVFLLLKGRLPSIKEGK
CCCCCEECHHHHHHHHHHCCCHHHHHCCCCHHHHHHHHHHHHEEEEEECCCCCCCCCCH
LFNHVLVSFCDHGATPPSTQTARLVASSGSPLNAAVAGALLSFGHKHAGAIEKTMELYQS
HHHHHHHHHHHCCCCCCCCCHHEEEECCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHH
KIDSLMLTGDADIDNKQIASLAIDLYNEYIVSKNTKIPGFGHRYHNADPRADKLMELVIK
HHHHEEEECCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHH
EGCVGPHTKLALAIEDLLYQKKNIRLNVDGANAAILSDLGFDPKLGLGVFIIGRVPGIIA
HCCCCCCHHHHHHHHHHHHHHCCCEEEECCCCCHHHHHCCCCCCCCCCEEEECHHHHHHH
HIHEETIDEDEFRRFCDIDDIVYDGPGR
HHHHHCCCHHHHHHHCCHHHEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1311544 [H]