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The map label for this gene is atpI [H]

Identifier: 148642500

GI number: 148642500

Start: 420313

End: 422316

Strand: Reverse

Name: atpI [H]

Synonym: Msm_0440

Alternate gene names: 148642500

Gene position: 422316-420313 (Counterclockwise)

Preceding gene: 148642501

Following gene: 148642499

Centisome position: 22.79

GC content: 32.68

Gene sequence:

>2004_bases
ATGTTCAAGACAGCTAGAATGCGTAAAATTAGAATCGTTACTCTTGATGAGTACATATCCCCTACTGTTAGTGCACTCCA
CGAACAAGGATTAGTACAAATCAACGAGATTTCTGATAGTATTCAGCAAGATCCTGAATTAGCGGAGTTAGTAACTCCTT
CAAAAGCATCTGCTTTCACTGGTAAGTTATCTTCACTTTTAATGAAAACAAGTGCTATTTCTGAACTATTAGGAAATTCT
TTATCCGAAGGCCATGGGATCAAAGACACAATAAAGTCTTTTATTAGTCCAGAAATGCCTATTCAAAAAGAAGTTGGGGA
TTTAGATACTGAAGCTTTAATAAATAAAGCAGAAGACCTTTTGGCTCAAGTTGAAAGTGAAACAAAAGTTATTGAAGGTA
AATTTTCCGCACTCGACTCTGAAACAAGTGTATTGACTTCTAATAAAAGTTTAGCTAAGCGTTTATATAATTTAGACATG
GACTTGGCTCTTTTAAAAGATTCTAAGTACACTTCCATAACTGTTGGTAGGATTAATGCTGAGTCTGCTTCAGAAATTGA
AAGTAACTTAAGTAAATTGACTGATGAATTAGATGTTTTTATAGTCCCTAATGATGATAAAGAAACTGCAAATATTATCG
TAGTGACTTTAAAAGAATTCGGCGAAGATGTTTATTCAACACTTCGTAAATTTGACTTTGAGAGAGTTGAAGTTTCCAAT
GTTGAGGGAACTCCACAGCAAATTATCTCAAGTGCTGATTCTAGATTGGTAACAATAGAATCTGAACGTAATTCAGCTAA
AAGTGATTTAAGAGCTATTGCTGAAAGATGGGATGACGATATTTTATCTCTTAAAGAAGAATTAGAAAATGAAAAAGAAA
AGAATGAAATACTTGCTGCTTTTGTTCAAACAAAAGATACCTATATGTTAGAAGCATGGGTACCTGTTAAAGATACTGAT
AAAGTTGAGCAATTAGTAGAAAAAAGTTCTGATGGACATTGTACCTTTGAATTAATTGATGTTGAAGGTACTGATGATGA
AGATGTACCTATTTTACAAACTAATAAAGGTTATGTAAAACCTTATGAGGTTCTTGTGGATATGTATTCTCCAGTAAGAT
ATAATGCTATAGATCCAACATTCTTTGTAGCAGTTGTGTTCCCGTTCTTATTCGGGTACTGTTTAACTGATGCATTTTAT
GGTGCTATTGTAGCTATCATAGGTGTTGTTTTAGTAAGGGGTATGGGTAAACTCAATGATACAATGAAATCATTCGGTTA
TATTCTTACAGCGTGTGGTATTTGGGCAATTATATTGGGTCTTCTAACTAATGGTTTGTTAGGAGATTTCACACAAAGAA
TGTTGAATTATAAGTTGCCTACTGTTGTGCCTGCTGTTGAAGCTTTTGTACATCCAGATACTATTTTAATAATAGCAATA
GCTATTGGTATAATTTATACTAATATTGGTTTTGTTATTGGAGCTATCAATAATTTCAGATATGGAGAAATAAAAGAAGC
TATTGGATCTCAGCTTTGCTGGTTTGTTTTAGAAGCCGGTATTATATTTTTAGTATTAGGATTTATGATGCCTGCAATAG
GTATGATCGGATACGGAATTGGAGCAGTTTTAATAATTGCATGTCTTGCTATGTTAATATATGCTAATGGAGCTTATGGA
GTTATGGATGTTTTCGGATTTATGGGAGATGTCTTGTCTTATGCTCGTCTTTTAGCATTATGTTTAGCTACAGGAGGTAT
TGCTATGACTGTAAATATCTTAACTAACTTATGTAATGATATGATTCCAGTTATTGGTATTGTTCTTGCAATTTTCATAT
TTATATTCGGACATATTGCAAACTTCTTGTTCCAAATTTTAGGTGCATTTATTAACTCTTTACGTCTTCATTACGTGGAG
TTCTTTTCACAGTTCTATATGGAAGGTAAAAACAAGTTCCAAGCTTTCAAAGCAAACAGAACTTTTACAAAACTTAAAAA
TTAA

Upstream 100 bases:

>100_bases
GATGGAGAAGCTAATGTAGCTTCCTTAAAAGAAAAAGCTATGGCAAATGTAGATGATGCTGCTTCTATTATTGTCAAAAA
TGTTTTATAGTGTGAGATTA

Downstream 100 bases:

>100_bases
AATTTTTTATTTAAATATATCAAAATTAATTATTATTCAAAGGTGAATTAAATATGGTGGATATTGCTTTAGGTACTGCT
TTAGCAGCTATTGGTGCTGG

Product: V-type ATP synthase subunit I

Products: ADP; phosphate; H+

Alternate protein names: V-ATPase subunit I [H]

Number of amino acids: Translated: 667; Mature: 667

Protein sequence:

>667_residues
MFKTARMRKIRIVTLDEYISPTVSALHEQGLVQINEISDSIQQDPELAELVTPSKASAFTGKLSSLLMKTSAISELLGNS
LSEGHGIKDTIKSFISPEMPIQKEVGDLDTEALINKAEDLLAQVESETKVIEGKFSALDSETSVLTSNKSLAKRLYNLDM
DLALLKDSKYTSITVGRINAESASEIESNLSKLTDELDVFIVPNDDKETANIIVVTLKEFGEDVYSTLRKFDFERVEVSN
VEGTPQQIISSADSRLVTIESERNSAKSDLRAIAERWDDDILSLKEELENEKEKNEILAAFVQTKDTYMLEAWVPVKDTD
KVEQLVEKSSDGHCTFELIDVEGTDDEDVPILQTNKGYVKPYEVLVDMYSPVRYNAIDPTFFVAVVFPFLFGYCLTDAFY
GAIVAIIGVVLVRGMGKLNDTMKSFGYILTACGIWAIILGLLTNGLLGDFTQRMLNYKLPTVVPAVEAFVHPDTILIIAI
AIGIIYTNIGFVIGAINNFRYGEIKEAIGSQLCWFVLEAGIIFLVLGFMMPAIGMIGYGIGAVLIIACLAMLIYANGAYG
VMDVFGFMGDVLSYARLLALCLATGGIAMTVNILTNLCNDMIPVIGIVLAIFIFIFGHIANFLFQILGAFINSLRLHYVE
FFSQFYMEGKNKFQAFKANRTFTKLKN

Sequences:

>Translated_667_residues
MFKTARMRKIRIVTLDEYISPTVSALHEQGLVQINEISDSIQQDPELAELVTPSKASAFTGKLSSLLMKTSAISELLGNS
LSEGHGIKDTIKSFISPEMPIQKEVGDLDTEALINKAEDLLAQVESETKVIEGKFSALDSETSVLTSNKSLAKRLYNLDM
DLALLKDSKYTSITVGRINAESASEIESNLSKLTDELDVFIVPNDDKETANIIVVTLKEFGEDVYSTLRKFDFERVEVSN
VEGTPQQIISSADSRLVTIESERNSAKSDLRAIAERWDDDILSLKEELENEKEKNEILAAFVQTKDTYMLEAWVPVKDTD
KVEQLVEKSSDGHCTFELIDVEGTDDEDVPILQTNKGYVKPYEVLVDMYSPVRYNAIDPTFFVAVVFPFLFGYCLTDAFY
GAIVAIIGVVLVRGMGKLNDTMKSFGYILTACGIWAIILGLLTNGLLGDFTQRMLNYKLPTVVPAVEAFVHPDTILIIAI
AIGIIYTNIGFVIGAINNFRYGEIKEAIGSQLCWFVLEAGIIFLVLGFMMPAIGMIGYGIGAVLIIACLAMLIYANGAYG
VMDVFGFMGDVLSYARLLALCLATGGIAMTVNILTNLCNDMIPVIGIVLAIFIFIFGHIANFLFQILGAFINSLRLHYVE
FFSQFYMEGKNKFQAFKANRTFTKLKN
>Mature_667_residues
MFKTARMRKIRIVTLDEYISPTVSALHEQGLVQINEISDSIQQDPELAELVTPSKASAFTGKLSSLLMKTSAISELLGNS
LSEGHGIKDTIKSFISPEMPIQKEVGDLDTEALINKAEDLLAQVESETKVIEGKFSALDSETSVLTSNKSLAKRLYNLDM
DLALLKDSKYTSITVGRINAESASEIESNLSKLTDELDVFIVPNDDKETANIIVVTLKEFGEDVYSTLRKFDFERVEVSN
VEGTPQQIISSADSRLVTIESERNSAKSDLRAIAERWDDDILSLKEELENEKEKNEILAAFVQTKDTYMLEAWVPVKDTD
KVEQLVEKSSDGHCTFELIDVEGTDDEDVPILQTNKGYVKPYEVLVDMYSPVRYNAIDPTFFVAVVFPFLFGYCLTDAFY
GAIVAIIGVVLVRGMGKLNDTMKSFGYILTACGIWAIILGLLTNGLLGDFTQRMLNYKLPTVVPAVEAFVHPDTILIIAI
AIGIIYTNIGFVIGAINNFRYGEIKEAIGSQLCWFVLEAGIIFLVLGFMMPAIGMIGYGIGAVLIIACLAMLIYANGAYG
VMDVFGFMGDVLSYARLLALCLATGGIAMTVNILTNLCNDMIPVIGIVLAIFIFIFGHIANFLFQILGAFINSLRLHYVE
FFSQFYMEGKNKFQAFKANRTFTKLKN

Specific function: Produces ATP from ADP in the presence of a proton gradient across the membrane [H]

COG id: COG1269

COG function: function code C; Archaeal/vacuolar-type H+-ATPase subunit I

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the V-ATPase 116 kDa subunit family [H]

Homologues:

Organism=Drosophila melanogaster, GI21357061, Length=501, Percent_Identity=20.3592814371257, Blast_Score=70, Evalue=5e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002490 [H]

Pfam domain/function: PF01496 V_ATPase_I [H]

EC number: 3.6.3.14

Molecular weight: Translated: 73775; Mature: 73775

Theoretical pI: Translated: 4.43; Mature: 4.43

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFKTARMRKIRIVTLDEYISPTVSALHEQGLVQINEISDSIQQDPELAELVTPSKASAFT
CCCCCCCCEEEEEEHHHHHHHHHHHHHHCCCEEHHHHHHHHHCCCCHHHHCCCCCHHHHH
GKLSSLLMKTSAISELLGNSLSEGHGIKDTIKSFISPEMPIQKEVGDLDTEALINKAEDL
HHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHCCCCCCHHHHHCCCCHHHHHHHHHHH
LAQVESETKVIEGKFSALDSETSVLTSNKSLAKRLYNLDMDLALLKDSKYTSITVGRINA
HHHHHHHHHHHHHHHHHCCCCHHHHCCCHHHHHHHHCCCCCCEEECCCCCCEEEEEECCC
ESASEIESNLSKLTDELDVFIVPNDDKETANIIVVTLKEFGEDVYSTLRKFDFERVEVSN
CHHHHHHHHHHHHHHCCEEEEECCCCCCCCCEEEEEHHHHCHHHHHHHHHCCCHHEEECC
VEGTPQQIISSADSRLVTIESERNSAKSDLRAIAERWDDDILSLKEELENEKEKNEILAA
CCCCHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHH
FVQTKDTYMLEAWVPVKDTDKVEQLVEKSSDGHCTFELIDVEGTDDEDVPILQTNKGYVK
HHHCCCCEEEEEECCCCCCHHHHHHHHCCCCCCEEEEEEEECCCCCCCCCEEECCCCCCC
PYEVLVDMYSPVRYNAIDPTFFVAVVFPFLFGYCLTDAFYGAIVAIIGVVLVRGMGKLND
HHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHH
TMKSFGYILTACGIWAIILGLLTNGLLGDFTQRMLNYKLPTVVPAVEAFVHPDTILIIAI
HHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCHHHHHHHHHHCCCHHHHHHH
AIGIIYTNIGFVIGAINNFRYGEIKEAIGSQLCWFVLEAGIIFLVLGFMMPAIGMIGYGI
HHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GAVLIIACLAMLIYANGAYGVMDVFGFMGDVLSYARLLALCLATGGIAMTVNILTNLCND
HHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHH
MIPVIGIVLAIFIFIFGHIANFLFQILGAFINSLRLHYVEFFSQFYMEGKNKFQAFKANR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCC
TFTKLKN
CHHHCCC
>Mature Secondary Structure
MFKTARMRKIRIVTLDEYISPTVSALHEQGLVQINEISDSIQQDPELAELVTPSKASAFT
CCCCCCCCEEEEEEHHHHHHHHHHHHHHCCCEEHHHHHHHHHCCCCHHHHCCCCCHHHHH
GKLSSLLMKTSAISELLGNSLSEGHGIKDTIKSFISPEMPIQKEVGDLDTEALINKAEDL
HHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHCCCCCCHHHHHCCCCHHHHHHHHHHH
LAQVESETKVIEGKFSALDSETSVLTSNKSLAKRLYNLDMDLALLKDSKYTSITVGRINA
HHHHHHHHHHHHHHHHHCCCCHHHHCCCHHHHHHHHCCCCCCEEECCCCCCEEEEEECCC
ESASEIESNLSKLTDELDVFIVPNDDKETANIIVVTLKEFGEDVYSTLRKFDFERVEVSN
CHHHHHHHHHHHHHHCCEEEEECCCCCCCCCEEEEEHHHHCHHHHHHHHHCCCHHEEECC
VEGTPQQIISSADSRLVTIESERNSAKSDLRAIAERWDDDILSLKEELENEKEKNEILAA
CCCCHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHH
FVQTKDTYMLEAWVPVKDTDKVEQLVEKSSDGHCTFELIDVEGTDDEDVPILQTNKGYVK
HHHCCCCEEEEEECCCCCCHHHHHHHHCCCCCCEEEEEEEECCCCCCCCCEEECCCCCCC
PYEVLVDMYSPVRYNAIDPTFFVAVVFPFLFGYCLTDAFYGAIVAIIGVVLVRGMGKLND
HHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHH
TMKSFGYILTACGIWAIILGLLTNGLLGDFTQRMLNYKLPTVVPAVEAFVHPDTILIIAI
HHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCHHHHHHHHHHCCCHHHHHHH
AIGIIYTNIGFVIGAINNFRYGEIKEAIGSQLCWFVLEAGIIFLVLGFMMPAIGMIGYGI
HHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GAVLIIACLAMLIYANGAYGVMDVFGFMGDVLSYARLLALCLATGGIAMTVNILTNLCND
HHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHH
MIPVIGIVLAIFIFIFGHIANFLFQILGAFINSLRLHYVEFFSQFYMEGKNKFQAFKANR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCC
TFTKLKN
CHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; H2O; H+

Specific reaction: ATP + H2O + H+(in) = ADP + phosphate + H+(out)

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9371463 [H]