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The map label for this gene is argJ [H]

Identifier: 148642439

GI number: 148642439

Start: 360321

End: 361541

Strand: Reverse

Name: argJ [H]

Synonym: Msm_0379

Alternate gene names: 148642439

Gene position: 361541-360321 (Counterclockwise)

Preceding gene: 148642440

Following gene: 148642438

Centisome position: 19.51

GC content: 34.97

Gene sequence:

>1221_bases
ATGATATTTAAAGAACTTGATGGTGGATTGTCAGTTATTGATAATCTTAAAGTGGCAGGTGCTAAAGAAGGAAAATATGG
TGTTGCAGTTATTGTAAGTGAAAATAGTGATGCTTCAGCAGTATTTACATCAAATAAAATAGTGGCTGCTCCTGTAATAT
ATACTAAAAAGGTAGTTGAAAAAGGAAAAGTTTCAGCAGTATTTGTTAATAGTGGAAATGCTAATTGTTTTACAGGCAAT
CAGGGAATTGAAGATTGTGAATCATTAGTTGAACTGGTTTCTAAAGAGCTGAATATTCCTAAAGGAGAAATAGCTATTTC
TTCAACTGGGGTTATTGGCCGTAAAATGCCTCTTGATGTTATAACTGGTGTGGCTTCTAAAGTATTTTCCAGTCTTGGAA
ACAAACCGGAAGATTCATTGGCAGCTGCAAATGCCATTATGACTACTGATAAAATTCCAAAACAGTGTGCATTGGAAGTC
ACATTAACTAATGGTGAAAAAGTAAAAATTGCAGGAATTACAAAAGGCAGCGGAATGATTGCTCCAAATATGGGAACCAT
GCTGTCATTTATTGTAACTGATGGAGTAATGGAAAGTAAATATATTAATAAAGCTCTTAAAAAAGCTGCAAATAAAAGTT
TTAACATGATCGTTGTTGATGGTGATGAGAGTACAAATGATACCTGTTTGCTCATGGCAAATAAGGCGTCTGGAGTCAAT
ATAGTCAATGACGGTGAAATTGATCCGAATTTCCAGGAAGCCCTTGAGTATCTTTGTATTGATTTGGCTAAAAAAATGGT
TAAAGATGGTGAAGGTGCATCTAAGGTTATTGAAGCAAATATTTATGGAGCTAAAAATATTGATGAAGCCAGATTGGCAG
CTAAGGCAATTGTAACTTCTCCTTTATTTAAATCTGCCGTATTTGGTGGTGATCCAAATTGGGGAAGGATAGTCTCAGCA
ATCGGTTATTCCGGAGCAGATGTAAGTGCAGATACAGTAACAATAGCTATAGCTAATAAACAAGATGAAGTTGACCTTGT
AAAAGATGGTGAAATTCTTGCTTTTGAAGGAACTGATAATCTTTTAAGAGCTGAGAAAATCATGCTCGGAGAAGAGGTCA
TTGTAAATGTTGATCTTAATAAAGGTGATGGTGAAGCTACAGCTTGGGGCTGTGATTTAAGTTATGATTATGTGAAAATC
AATGCTGAATATACTACTTAA

Upstream 100 bases:

>100_bases
CTTACGATTCAGAGAAGGATGAATCAAATTACCTTGAAAAAGGTGAATCAAACTTGGATTATTCGGATGATTATTAATTT
ATTTTTTGTAAGGAAGTAAT

Downstream 100 bases:

>100_bases
AGAAAAGATATAAATACTTTAAGAAGTAAATATTTTTATGTTATAGAAATTCTATTTTTGATTTTCGATTAAAATGATAT
TGAATCAAATTTTAACTATT

Product: bifunctional ornithine acetyltransferase/N-acetylglutamate synthase protein

Products: NA

Alternate protein names: Glutamate N-acetyltransferase; Ornithine acetyltransferase; OATase; Ornithine transacetylase; Amino-acid acetyltransferase; N-acetylglutamate synthase; AGS [H]

Number of amino acids: Translated: 406; Mature: 406

Protein sequence:

>406_residues
MIFKELDGGLSVIDNLKVAGAKEGKYGVAVIVSENSDASAVFTSNKIVAAPVIYTKKVVEKGKVSAVFVNSGNANCFTGN
QGIEDCESLVELVSKELNIPKGEIAISSTGVIGRKMPLDVITGVASKVFSSLGNKPEDSLAAANAIMTTDKIPKQCALEV
TLTNGEKVKIAGITKGSGMIAPNMGTMLSFIVTDGVMESKYINKALKKAANKSFNMIVVDGDESTNDTCLLMANKASGVN
IVNDGEIDPNFQEALEYLCIDLAKKMVKDGEGASKVIEANIYGAKNIDEARLAAKAIVTSPLFKSAVFGGDPNWGRIVSA
IGYSGADVSADTVTIAIANKQDEVDLVKDGEILAFEGTDNLLRAEKIMLGEEVIVNVDLNKGDGEATAWGCDLSYDYVKI
NAEYTT

Sequences:

>Translated_406_residues
MIFKELDGGLSVIDNLKVAGAKEGKYGVAVIVSENSDASAVFTSNKIVAAPVIYTKKVVEKGKVSAVFVNSGNANCFTGN
QGIEDCESLVELVSKELNIPKGEIAISSTGVIGRKMPLDVITGVASKVFSSLGNKPEDSLAAANAIMTTDKIPKQCALEV
TLTNGEKVKIAGITKGSGMIAPNMGTMLSFIVTDGVMESKYINKALKKAANKSFNMIVVDGDESTNDTCLLMANKASGVN
IVNDGEIDPNFQEALEYLCIDLAKKMVKDGEGASKVIEANIYGAKNIDEARLAAKAIVTSPLFKSAVFGGDPNWGRIVSA
IGYSGADVSADTVTIAIANKQDEVDLVKDGEILAFEGTDNLLRAEKIMLGEEVIVNVDLNKGDGEATAWGCDLSYDYVKI
NAEYTT
>Mature_406_residues
MIFKELDGGLSVIDNLKVAGAKEGKYGVAVIVSENSDASAVFTSNKIVAAPVIYTKKVVEKGKVSAVFVNSGNANCFTGN
QGIEDCESLVELVSKELNIPKGEIAISSTGVIGRKMPLDVITGVASKVFSSLGNKPEDSLAAANAIMTTDKIPKQCALEV
TLTNGEKVKIAGITKGSGMIAPNMGTMLSFIVTDGVMESKYINKALKKAANKSFNMIVVDGDESTNDTCLLMANKASGVN
IVNDGEIDPNFQEALEYLCIDLAKKMVKDGEGASKVIEANIYGAKNIDEARLAAKAIVTSPLFKSAVFGGDPNWGRIVSA
IGYSGADVSADTVTIAIANKQDEVDLVKDGEILAFEGTDNLLRAEKIMLGEEVIVNVDLNKGDGEATAWGCDLSYDYVKI
NAEYTT

Specific function: Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis:the synthesis of acetylglutamate from glutamate and acetyl-CoA, and of ornithine by transacetylation between acetylornithine and glutamate [H]

COG id: COG1364

COG function: function code E; N-acetylglutamate synthase (N-acetylornithine aminotransferase)

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ArgJ family [H]

Homologues:

Organism=Saccharomyces cerevisiae, GI6323707, Length=404, Percent_Identity=39.3564356435644, Blast_Score=242, Evalue=7e-65,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002813
- InterPro:   IPR016117 [H]

Pfam domain/function: PF01960 ArgJ [H]

EC number: =2.3.1.35; =2.3.1.1 [H]

Molecular weight: Translated: 42808; Mature: 42808

Theoretical pI: Translated: 4.48; Mature: 4.48

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIFKELDGGLSVIDNLKVAGAKEGKYGVAVIVSENSDASAVFTSNKIVAAPVIYTKKVVE
CCCCCCCCCHHHHHCCEECCCCCCCCEEEEEEECCCCCCEEEECCCEEEECHHHHHHHHH
KGKVSAVFVNSGNANCFTGNQGIEDCESLVELVSKELNIPKGEIAISSTGVIGRKMPLDV
CCCEEEEEEECCCCEEEECCCCHHHHHHHHHHHHHHCCCCCCCEEEECCCCCCCCCCHHH
ITGVASKVFSSLGNKPEDSLAAANAIMTTDKIPKQCALEVTLTNGEKVKIAGITKGSGMI
HHHHHHHHHHHHCCCCCHHHHHHHHHEECCCCCCCEEEEEEECCCCEEEEEEEECCCCEE
APNMGTMLSFIVTDGVMESKYINKALKKAANKSFNMIVVDGDESTNDTCLLMANKASGVN
CCCHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCEEEEEEECCCCCE
IVNDGEIDPNFQEALEYLCIDLAKKMVKDGEGASKVIEANIYGAKNIDEARLAAKAIVTS
EEECCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCCCHHHHHHHHHHHH
PLFKSAVFGGDPNWGRIVSAIGYSGADVSADTVTIAIANKQDEVDLVKDGEILAFEGTDN
HHHHHHHCCCCCCHHHHHHHHCCCCCCCCCCEEEEEEECCCCCEEEEECCCEEEECCCCC
LLRAEKIMLGEEVIVNVDLNKGDGEATAWGCDLSYDYVKINAEYTT
HHHHHHHEECCEEEEEEECCCCCCCCEEEECCCEEEEEEEEEEECC
>Mature Secondary Structure
MIFKELDGGLSVIDNLKVAGAKEGKYGVAVIVSENSDASAVFTSNKIVAAPVIYTKKVVE
CCCCCCCCCHHHHHCCEECCCCCCCCEEEEEEECCCCCCEEEECCCEEEECHHHHHHHHH
KGKVSAVFVNSGNANCFTGNQGIEDCESLVELVSKELNIPKGEIAISSTGVIGRKMPLDV
CCCEEEEEEECCCCEEEECCCCHHHHHHHHHHHHHHCCCCCCCEEEECCCCCCCCCCHHH
ITGVASKVFSSLGNKPEDSLAAANAIMTTDKIPKQCALEVTLTNGEKVKIAGITKGSGMI
HHHHHHHHHHHHCCCCCHHHHHHHHHEECCCCCCCEEEEEEECCCCEEEEEEEECCCCEE
APNMGTMLSFIVTDGVMESKYINKALKKAANKSFNMIVVDGDESTNDTCLLMANKASGVN
CCCHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCEEEEEEECCCCCE
IVNDGEIDPNFQEALEYLCIDLAKKMVKDGEGASKVIEANIYGAKNIDEARLAAKAIVTS
EEECCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCCCHHHHHHHHHHHH
PLFKSAVFGGDPNWGRIVSAIGYSGADVSADTVTIAIANKQDEVDLVKDGEILAFEGTDN
HHHHHHHCCCCCCHHHHHHHHCCCCCCCCCCEEEEEEECCCCCEEEEECCCEEEECCCCC
LLRAEKIMLGEEVIVNVDLNKGDGEATAWGCDLSYDYVKINAEYTT
HHHHHHHEECCEEEEEEECCCCCCCCEEEECCCEEEEEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9371463 [H]