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The map label for this gene is carB [H]

Identifier: 148642421

GI number: 148642421

Start: 344605

End: 345708

Strand: Reverse

Name: carB [H]

Synonym: Msm_0361

Alternate gene names: 148642421

Gene position: 345708-344605 (Counterclockwise)

Preceding gene: 148642422

Following gene: 148642420

Centisome position: 18.66

GC content: 33.42

Gene sequence:

>1104_bases
ATGAAAATTTTATTTATCGGTTCAAGATTGTATGATGATATAGATTATTATGTTAGGGAAAACGGTATTGAAAGCATAAT
TACTGAATCTAATGAAGATGCCATAAATCTGGATTTGCCTGATCAGGTTTTTATCGTGCCTAGAGGTATGGACAGTCCAA
AACAGATAGCTATCAGTCAGAATGTAGATGCTGTTGTACCTTTGATTGGTATTGATCCTCCATTAATAGAAGTAGCTAAA
ATGAAAGAGGAACTTGAAGCTGAAACTGATATTCCTGTAATTGCAGCTAATGTTCGTGCAGTTAGATTAACTTCTGATAA
AATTAAAACCAAAGAGTTCTACAATGAAATAGGAGTACCTACTCCACAATATCAGATATTGGCTAAGGATGATTTTGAAA
GCAAATTGAAAATGGAGTTTCCGGTTGTTTTAAAGCAAGGTCAGGGACAGGGCGGAAAAGATATTAAAGTAGCTGAATCT
TTAGATGATGTTAAAGAGTATTTTGAAGAATTTGACCATGCTTTATGTGAAAAATTTATTGAAGGTTCTGAAATTTCTAT
TGAAGTATTGGGGTATAATGGTGAATATGTGCCTTTATCTCCAATTTATAAAGGAGAAACAACTTTGGAGGGAATTCATC
CTTTAAATAAGATTAAAACAGCTCCCTGTTTAGTTGAAGGATTGGATAATAATCTTGTTCAGAGGACTGCATATAAAGTA
GCTAAGAATTTAGGTTCTGACGGTATTTTTGAAATGGATTTCATGTTTTCAAAAGATGAACAGCAACTGTATGCTATTGA
AGTTAACACAAGGCCTAATGGAACCAGATATTTAACAACAGCCACCTGTGGTGTTAATTCTTTATGTGAATTGGTAAATA
TGGCTGCAGGCAAATTTTCCATTAAGGATATTCAGGATAAATTGGAATATTATTATGCTACAGAAATTCCTATTGGGCGT
TACAAAGGTCCGGATTTAAACGAACCTTTAAAATCCTTTAAAAACAATGATTGGGTGGTTCACGGACCTGAAGGATATCA
AAGAATTACAATCAGGGCAGATTCAAAAGAGCAATTAGACAGATATGTTGAAGATTTGATTTAA

Upstream 100 bases:

>100_bases
TTGTTGGTATTGAACCTGAATCCATGGATTATTCAGATAAGCCAACACCAGCAGTTCAAAAGGGAGCCTACAAGTTTATA
AATATTTTGAAGGAGATTTT

Downstream 100 bases:

>100_bases
TAATAACTTAAACACTATTAAATTAATTTTATATAACATTAGAAATAAAATTAATATGATACATAATTTATGTGTGGTAA
AATGAATAATGGGGATATGT

Product: carbamoyl-phosphate synthase, large subunit, CarB

Products: NA

Alternate protein names: Carbamoyl-phosphate synthetase ammonia chain [H]

Number of amino acids: Translated: 367; Mature: 367

Protein sequence:

>367_residues
MKILFIGSRLYDDIDYYVRENGIESIITESNEDAINLDLPDQVFIVPRGMDSPKQIAISQNVDAVVPLIGIDPPLIEVAK
MKEELEAETDIPVIAANVRAVRLTSDKIKTKEFYNEIGVPTPQYQILAKDDFESKLKMEFPVVLKQGQGQGGKDIKVAES
LDDVKEYFEEFDHALCEKFIEGSEISIEVLGYNGEYVPLSPIYKGETTLEGIHPLNKIKTAPCLVEGLDNNLVQRTAYKV
AKNLGSDGIFEMDFMFSKDEQQLYAIEVNTRPNGTRYLTTATCGVNSLCELVNMAAGKFSIKDIQDKLEYYYATEIPIGR
YKGPDLNEPLKSFKNNDWVVHGPEGYQRITIRADSKEQLDRYVEDLI

Sequences:

>Translated_367_residues
MKILFIGSRLYDDIDYYVRENGIESIITESNEDAINLDLPDQVFIVPRGMDSPKQIAISQNVDAVVPLIGIDPPLIEVAK
MKEELEAETDIPVIAANVRAVRLTSDKIKTKEFYNEIGVPTPQYQILAKDDFESKLKMEFPVVLKQGQGQGGKDIKVAES
LDDVKEYFEEFDHALCEKFIEGSEISIEVLGYNGEYVPLSPIYKGETTLEGIHPLNKIKTAPCLVEGLDNNLVQRTAYKV
AKNLGSDGIFEMDFMFSKDEQQLYAIEVNTRPNGTRYLTTATCGVNSLCELVNMAAGKFSIKDIQDKLEYYYATEIPIGR
YKGPDLNEPLKSFKNNDWVVHGPEGYQRITIRADSKEQLDRYVEDLI
>Mature_367_residues
MKILFIGSRLYDDIDYYVRENGIESIITESNEDAINLDLPDQVFIVPRGMDSPKQIAISQNVDAVVPLIGIDPPLIEVAK
MKEELEAETDIPVIAANVRAVRLTSDKIKTKEFYNEIGVPTPQYQILAKDDFESKLKMEFPVVLKQGQGQGGKDIKVAES
LDDVKEYFEEFDHALCEKFIEGSEISIEVLGYNGEYVPLSPIYKGETTLEGIHPLNKIKTAPCLVEGLDNNLVQRTAYKV
AKNLGSDGIFEMDFMFSKDEQQLYAIEVNTRPNGTRYLTTATCGVNSLCELVNMAAGKFSIKDIQDKLEYYYATEIPIGR
YKGPDLNEPLKSFKNNDWVVHGPEGYQRITIRADSKEQLDRYVEDLI

Specific function: Cell Wall Formation. [C]

COG id: COG0458

COG function: function code EF; Carbamoylphosphate synthase large subunit (split gene in MJ)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 ATP-grasp domains [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011761
- InterPro:   IPR013815
- InterPro:   IPR013816
- InterPro:   IPR006275
- InterPro:   IPR005479
- InterPro:   IPR005483
- InterPro:   IPR005481
- InterPro:   IPR005480
- InterPro:   IPR011607
- InterPro:   IPR013817
- InterPro:   IPR016185 [H]

Pfam domain/function: PF00289 CPSase_L_chain; PF02786 CPSase_L_D2; PF02787 CPSase_L_D3; PF02142 MGS [H]

EC number: =6.3.5.5 [H]

Molecular weight: Translated: 41404; Mature: 41404

Theoretical pI: Translated: 4.35; Mature: 4.35

Prosite motif: PS50975 ATP_GRASP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKILFIGSRLYDDIDYYVRENGIESIITESNEDAINLDLPDQVFIVPRGMDSPKQIAISQ
CEEEEECCHHHHHHHHHHHHCCHHHHHCCCCCCEEEECCCCEEEEEECCCCCCCEEEEEC
NVDAVVPLIGIDPPLIEVAKMKEELEAETDIPVIAANVRAVRLTSDKIKTKEFYNEIGVP
CCCEEEEEECCCCCHHHHHHHHHHHHCCCCCCEEEECEEEEEEECCHHHHHHHHHHHCCC
TPQYQILAKDDFESKLKMEFPVVLKQGQGQGGKDIKVAESLDDVKEYFEEFDHALCEKFI
CCCEEEEECCCCCCCEEEECCEEEECCCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHH
EGSEISIEVLGYNGEYVPLSPIYKGETTLEGIHPLNKIKTAPCLVEGLDNNLVQRTAYKV
CCCCEEEEEEECCCCEEECCCCCCCCCCHHCCCCHHHHCCCCHHHHCCCCHHHHHHHHHH
AKNLGSDGIFEMDFMFSKDEQQLYAIEVNTRPNGTRYLTTATCGVNSLCELVNMAAGKFS
HHHCCCCCEEEEEEEECCCCCEEEEEEEECCCCCCEEEEEECCCHHHHHHHHHHHCCCCC
IKDIQDKLEYYYATEIPIGRYKGPDLNEPLKSFKNNDWVVHGPEGYQRITIRADSKEQLD
HHHHHHHHHEEEEECCCCCCCCCCCCCHHHHHHCCCCEEEECCCCCEEEEEEECCHHHHH
RYVEDLI
HHHHHCC
>Mature Secondary Structure
MKILFIGSRLYDDIDYYVRENGIESIITESNEDAINLDLPDQVFIVPRGMDSPKQIAISQ
CEEEEECCHHHHHHHHHHHHCCHHHHHCCCCCCEEEECCCCEEEEEECCCCCCCEEEEEC
NVDAVVPLIGIDPPLIEVAKMKEELEAETDIPVIAANVRAVRLTSDKIKTKEFYNEIGVP
CCCEEEEEECCCCCHHHHHHHHHHHHCCCCCCEEEECEEEEEEECCHHHHHHHHHHHCCC
TPQYQILAKDDFESKLKMEFPVVLKQGQGQGGKDIKVAESLDDVKEYFEEFDHALCEKFI
CCCEEEEECCCCCCCEEEECCEEEECCCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHH
EGSEISIEVLGYNGEYVPLSPIYKGETTLEGIHPLNKIKTAPCLVEGLDNNLVQRTAYKV
CCCCEEEEEEECCCCEEECCCCCCCCCCHHCCCCHHHHCCCCHHHHCCCCHHHHHHHHHH
AKNLGSDGIFEMDFMFSKDEQQLYAIEVNTRPNGTRYLTTATCGVNSLCELVNMAAGKFS
HHHCCCCCEEEEEEEECCCCCEEEEEEEECCCCCCEEEEEECCCHHHHHHHHHHHCCCCC
IKDIQDKLEYYYATEIPIGRYKGPDLNEPLKSFKNNDWVVHGPEGYQRITIRADSKEQLD
HHHHHHHHHEEEEECCCCCCCCCCCCCHHHHHHCCCCEEEECCCCCEEEEEEECCHHHHH
RYVEDLI
HHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9923682 [H]