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The map label for this gene is yeeO [C]

Identifier: 148642312

GI number: 148642312

Start: 235769

End: 237133

Strand: Reverse

Name: yeeO [C]

Synonym: Msm_0252

Alternate gene names: 148642312

Gene position: 237133-235769 (Counterclockwise)

Preceding gene: 148642313

Following gene: 148642311

Centisome position: 12.8

GC content: 35.31

Gene sequence:

>1365_bases
ATGGCTAATAAAAATGTTGAAGTAATGAGAGGTAATCCTGAAACAGCTGTTAAGAAATTGGCGATTCCAATTATGATTTC
TATGCTTTTAACAGCATCATATAATATTATTGATGGGGTATGGATAGCAGGGCTTGGTCAGGAAGCTATTGCAGGTATTG
GTTTTATAACTCCGATTTTCATGATATTGAATGGGGTAAGTGTAGGACTTGGAAGTGGTGCAACAAGTAGTATAAGTCGT
TTTGTTGGAGCTAAAAATCATAAGAAAGCCAGTCAGTCAGCAGCACATTCTTTGCTGATTTTTTTAATAGCTTCCGTAGT
TTTAACAATTGTATTGTTAATTCTTCAGGAACCCTTGCTTAAATTATACGGAGCAAGTGGTGAGTCATTAGCTCAGGGAA
TTAAATATGGAACTCCTCTATTTTTAGGTTTATTTGCTTTTATATTTGCAAATGGTGCAAGTGGTATCCTTCGTGGAGAA
GGAGATATGAAAAGAGCAATGTATGCAGTTGTTGTTTCTGTAATATTAAATGCAATTTTAGATCCGATATGTATTTACAT
TTTAGGATGGGGATCAGCAGGAGCAGCTATTGCAACAATTTTAAGTTCCATCTGCTCAGCTATTGTTATATTATATTGGA
TTTTAGTTAAAAAGGACACATATGTGGATGTTAATTTAGGTGAATTTAAATTTGATTCCAGCATAGCTAAAGATATTTTA
AAAGTAGGTATTCCAGCATCAATGGATATGCTTGTAATGTCTATTGCAATGTCTTTGTATATGATATTTATTTCTTCAAT
TGCCGGAGAATTTGGAATAGCGTCATTTACATCAGGTCAGAGATTATACTTGTTTGCAATAATGCCGCTTACAGCTATTG
GAACAGCAGTTACAGCAGTTGTAGGCAGTTCATTTGGAGCTAAAAACGGAGAGTATATTTCAAGAGCACATAAATTCGGT
GCAAAATTTGGAATAATATTTGGAACATGTGTAACTCTTATTTTAGTAGTTTTTGCAACTCAGTTATCTACTATATTTGC
ATATACTGCTGAAACTGCACATTTGGTTCCGGAAATAACCAGATATTTGCAAATAGCCTGTCTTTCTCTACCTTTAACCG
GTGCAGGAATGGCTTCAACTTTCTTTTATCAGGGAATTGGAAAAGGAACAATCAGTTTATCCTGGACAATTATAAGGGAA
GTTATTTTCACTGTCGGAGCCACATTTTTCTTCGGAATTTATTTGGGCTGGGGATTAATTGGTATTTGGGCAGGATTGGC
TATCGGACGTGCTGCTGCCAGTATCTTAAATTACCTCTATGCAAGGTACACTATTAAGGGAATTAGAGAAACACTCGGAA
ACTAA

Upstream 100 bases:

>100_bases
CATTATATTAAAGTATTTGTTCTTCACGACAGATTTGACGATGATTGGATGGAAGAGAAAATTCAAAAAGAAATGGATAA
AATGAGGAAATAGGGTAATT

Downstream 100 bases:

>100_bases
TTTCTTTAATCTTTTTTTTATTTTTACTTTTTATACTTTTATTTAAATCTGTTTATAGGTTTTAAAAAGAAATATTTATA
TTTTAATTGGAATATAAATT

Product: Na+-driven multidrug efflux pump, NorM

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 454; Mature: 453

Protein sequence:

>454_residues
MANKNVEVMRGNPETAVKKLAIPIMISMLLTASYNIIDGVWIAGLGQEAIAGIGFITPIFMILNGVSVGLGSGATSSISR
FVGAKNHKKASQSAAHSLLIFLIASVVLTIVLLILQEPLLKLYGASGESLAQGIKYGTPLFLGLFAFIFANGASGILRGE
GDMKRAMYAVVVSVILNAILDPICIYILGWGSAGAAIATILSSICSAIVILYWILVKKDTYVDVNLGEFKFDSSIAKDIL
KVGIPASMDMLVMSIAMSLYMIFISSIAGEFGIASFTSGQRLYLFAIMPLTAIGTAVTAVVGSSFGAKNGEYISRAHKFG
AKFGIIFGTCVTLILVVFATQLSTIFAYTAETAHLVPEITRYLQIACLSLPLTGAGMASTFFYQGIGKGTISLSWTIIRE
VIFTVGATFFFGIYLGWGLIGIWAGLAIGRAAASILNYLYARYTIKGIRETLGN

Sequences:

>Translated_454_residues
MANKNVEVMRGNPETAVKKLAIPIMISMLLTASYNIIDGVWIAGLGQEAIAGIGFITPIFMILNGVSVGLGSGATSSISR
FVGAKNHKKASQSAAHSLLIFLIASVVLTIVLLILQEPLLKLYGASGESLAQGIKYGTPLFLGLFAFIFANGASGILRGE
GDMKRAMYAVVVSVILNAILDPICIYILGWGSAGAAIATILSSICSAIVILYWILVKKDTYVDVNLGEFKFDSSIAKDIL
KVGIPASMDMLVMSIAMSLYMIFISSIAGEFGIASFTSGQRLYLFAIMPLTAIGTAVTAVVGSSFGAKNGEYISRAHKFG
AKFGIIFGTCVTLILVVFATQLSTIFAYTAETAHLVPEITRYLQIACLSLPLTGAGMASTFFYQGIGKGTISLSWTIIRE
VIFTVGATFFFGIYLGWGLIGIWAGLAIGRAAASILNYLYARYTIKGIRETLGN
>Mature_453_residues
ANKNVEVMRGNPETAVKKLAIPIMISMLLTASYNIIDGVWIAGLGQEAIAGIGFITPIFMILNGVSVGLGSGATSSISRF
VGAKNHKKASQSAAHSLLIFLIASVVLTIVLLILQEPLLKLYGASGESLAQGIKYGTPLFLGLFAFIFANGASGILRGEG
DMKRAMYAVVVSVILNAILDPICIYILGWGSAGAAIATILSSICSAIVILYWILVKKDTYVDVNLGEFKFDSSIAKDILK
VGIPASMDMLVMSIAMSLYMIFISSIAGEFGIASFTSGQRLYLFAIMPLTAIGTAVTAVVGSSFGAKNGEYISRAHKFGA
KFGIIFGTCVTLILVVFATQLSTIFAYTAETAHLVPEITRYLQIACLSLPLTGAGMASTFFYQGIGKGTISLSWTIIREV
IFTVGATFFFGIYLGWGLIGIWAGLAIGRAAASILNYLYARYTIKGIRETLGN

Specific function: Unknown

COG id: COG0534

COG function: function code V; Na+-driven multidrug efflux pump

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family [H]

Homologues:

Organism=Escherichia coli, GI226510954, Length=441, Percent_Identity=22.6757369614512, Blast_Score=76, Evalue=4e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002528
- InterPro:   IPR015522 [H]

Pfam domain/function: PF01554 MatE [H]

EC number: NA

Molecular weight: Translated: 48192; Mature: 48061

Theoretical pI: Translated: 9.52; Mature: 9.52

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MANKNVEVMRGNPETAVKKLAIPIMISMLLTASYNIIDGVWIAGLGQEAIAGIGFITPIF
CCCCCCEEEECCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCHHHHHHHHHHHHHH
MILNGVSVGLGSGATSSISRFVGAKNHKKASQSAAHSLLIFLIASVVLTIVLLILQEPLL
HHHHCCHHCCCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KLYGASGESLAQGIKYGTPLFLGLFAFIFANGASGILRGEGDMKRAMYAVVVSVILNAIL
HHHCCCCHHHHHHHCCCCHHHHHHHHHHHHCCCCCEEECCCHHHHHHHHHHHHHHHHHHH
DPICIYILGWGSAGAAIATILSSICSAIVILYWILVKKDTYVDVNLGEFKFDSSIAKDIL
HHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCHHHHHHHH
KVGIPASMDMLVMSIAMSLYMIFISSIAGEFGIASFTSGQRLYLFAIMPLTAIGTAVTAV
HHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEHHHHHHHHHHHHHH
VGSSFGAKNGEYISRAHKFGAKFGIIFGTCVTLILVVFATQLSTIFAYTAETAHLVPEIT
HHCCCCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RYLQIACLSLPLTGAGMASTFFYQGIGKGTISLSWTIIREVIFTVGATFFFGIYLGWGLI
HHHHHHHHHCCCCCCCHHHHHHHHCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GIWAGLAIGRAAASILNYLYARYTIKGIRETLGN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
ANKNVEVMRGNPETAVKKLAIPIMISMLLTASYNIIDGVWIAGLGQEAIAGIGFITPIF
CCCCCEEEECCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCHHHHHHHHHHHHHH
MILNGVSVGLGSGATSSISRFVGAKNHKKASQSAAHSLLIFLIASVVLTIVLLILQEPLL
HHHHCCHHCCCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KLYGASGESLAQGIKYGTPLFLGLFAFIFANGASGILRGEGDMKRAMYAVVVSVILNAIL
HHHCCCCHHHHHHHCCCCHHHHHHHHHHHHCCCCCEEECCCHHHHHHHHHHHHHHHHHHH
DPICIYILGWGSAGAAIATILSSICSAIVILYWILVKKDTYVDVNLGEFKFDSSIAKDIL
HHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCHHHHHHHH
KVGIPASMDMLVMSIAMSLYMIFISSIAGEFGIASFTSGQRLYLFAIMPLTAIGTAVTAV
HHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEHHHHHHHHHHHHHH
VGSSFGAKNGEYISRAHKFGAKFGIIFGTCVTLILVVFATQLSTIFAYTAETAHLVPEIT
HHCCCCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RYLQIACLSLPLTGAGMASTFFYQGIGKGTISLSWTIIREVIFTVGATFFFGIYLGWGLI
HHHHHHHHHCCCCCCCHHHHHHHHCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GIWAGLAIGRAAASILNYLYARYTIKGIRETLGN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]