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The map label for this gene is trpS [H]

Identifier: 148642276

GI number: 148642276

Start: 202320

End: 203297

Strand: Reverse

Name: trpS [H]

Synonym: Msm_0216

Alternate gene names: 148642276

Gene position: 203297-202320 (Counterclockwise)

Preceding gene: 148642277

Following gene: 148642275

Centisome position: 10.97

GC content: 35.48

Gene sequence:

>978_bases
ATGAAAAGAGGAGTAATTTTTGGACATAGGGACTTTGATAAGGTCAATAATTTAATTAATAAAAAAGAGGACTTTGCAGT
TGTTGGTGGAATGATGCCAAGTGGCCAAATGCATATTGGTCATAAAATGGTTGTTGACCAGTTGAAATGGTATCAGGACA
AAGGTGCAATGTTATCTATTTTAATAGCTGATTTGGAATCATATGCTGCCAGAGACATGAGTTTTGAAAAGGCAAGAGAT
ATAGCTGTCAATGAATATTTAACTAATTATATTGCATTAGGTCTGGATTTGGAAGAGGATAATGTTAATGTTTATCTTCA
ATCCAAAAATGATACTCTCAGGGACTTGGCTTTTAAGGCTTCTAAAAAAACAAATTTCAATGAATTAAAAGCTATTTATG
GATTTACCCAATCAACAAACATTGCTCATATTCAGGCACCTCTTGTTCAGGTGGCGGATATTTTGCTTCCGCAGCTTGAA
GAATTTGGAGGTCCTAAAAGAGTTGTAGTTCCTGTTGGAGTAGATCAGGACCCTCATATAAGATTAACAAGAGATATAGC
TCACAAACTTAATGATGAATACGGATTCATCCCTCCGTCTTCCACTTATCACAGATTCCTTACTGGTTTAAGCGGAGATA
AAATGAGCAGCAGCAAACCTTCTACAGCAATTTATTTAAATGAAGATAGTGAAACTGCAGCTAAAAAAGTTAAAACAGCT
AAAACTGGTGGTAGAGAAAGCTTAAAAGAACAGCAGGAATTAGGCGGTCAGGTAGATAACTGTGTAATTTATGAAATGTT
TGTATACCACCTGATTGATGATGACAAAGAACTTGAAAAAATACGTCATGACTGTCTGGACGGGTCTTTACGCTGTGGAG
ACTGTAAAGCAAAAGCCAGTGAATTGATTGTTGAAATGTTTGATGAAATTCATGACAAACAGGATGAAGCTCGTGAAATA
GCTAATAATCTGATATAA

Upstream 100 bases:

>100_bases
ATGGGCATCATCAAGTGTAGATTATGATAAATTAGTCAATCAATTTGGAATTCAAAAATTTTCAGACTTGATTGATGATG
TGGAAAACCCTCACAGATTA

Downstream 100 bases:

>100_bases
TGTTAAATATTAAAAATGAAATTAAATCAGCTTTTTTAGAAAACAAAACTGCTGTTTATATTTCAATTATCCTTTTATTA
GGTACATTAATTGCAGGTTA

Product: tryptophanyl-tRNA synthetase

Products: NA

Alternate protein names: Tryptophan--tRNA ligase; TrpRS [H]

Number of amino acids: Translated: 325; Mature: 325

Protein sequence:

>325_residues
MKRGVIFGHRDFDKVNNLINKKEDFAVVGGMMPSGQMHIGHKMVVDQLKWYQDKGAMLSILIADLESYAARDMSFEKARD
IAVNEYLTNYIALGLDLEEDNVNVYLQSKNDTLRDLAFKASKKTNFNELKAIYGFTQSTNIAHIQAPLVQVADILLPQLE
EFGGPKRVVVPVGVDQDPHIRLTRDIAHKLNDEYGFIPPSSTYHRFLTGLSGDKMSSSKPSTAIYLNEDSETAAKKVKTA
KTGGRESLKEQQELGGQVDNCVIYEMFVYHLIDDDKELEKIRHDCLDGSLRCGDCKAKASELIVEMFDEIHDKQDEAREI
ANNLI

Sequences:

>Translated_325_residues
MKRGVIFGHRDFDKVNNLINKKEDFAVVGGMMPSGQMHIGHKMVVDQLKWYQDKGAMLSILIADLESYAARDMSFEKARD
IAVNEYLTNYIALGLDLEEDNVNVYLQSKNDTLRDLAFKASKKTNFNELKAIYGFTQSTNIAHIQAPLVQVADILLPQLE
EFGGPKRVVVPVGVDQDPHIRLTRDIAHKLNDEYGFIPPSSTYHRFLTGLSGDKMSSSKPSTAIYLNEDSETAAKKVKTA
KTGGRESLKEQQELGGQVDNCVIYEMFVYHLIDDDKELEKIRHDCLDGSLRCGDCKAKASELIVEMFDEIHDKQDEAREI
ANNLI
>Mature_325_residues
MKRGVIFGHRDFDKVNNLINKKEDFAVVGGMMPSGQMHIGHKMVVDQLKWYQDKGAMLSILIADLESYAARDMSFEKARD
IAVNEYLTNYIALGLDLEEDNVNVYLQSKNDTLRDLAFKASKKTNFNELKAIYGFTQSTNIAHIQAPLVQVADILLPQLE
EFGGPKRVVVPVGVDQDPHIRLTRDIAHKLNDEYGFIPPSSTYHRFLTGLSGDKMSSSKPSTAIYLNEDSETAAKKVKTA
KTGGRESLKEQQELGGQVDNCVIYEMFVYHLIDDDKELEKIRHDCLDGSLRCGDCKAKASELIVEMFDEIHDKQDEAREI
ANNLI

Specific function: Unknown

COG id: COG0180

COG function: function code J; Tryptophanyl-tRNA synthetase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family [H]

Homologues:

Organism=Homo sapiens, GI47419920, Length=336, Percent_Identity=30.6547619047619, Blast_Score=156, Evalue=3e-38,
Organism=Homo sapiens, GI47419918, Length=336, Percent_Identity=30.6547619047619, Blast_Score=156, Evalue=3e-38,
Organism=Homo sapiens, GI47419916, Length=336, Percent_Identity=30.6547619047619, Blast_Score=156, Evalue=3e-38,
Organism=Homo sapiens, GI47419914, Length=336, Percent_Identity=30.6547619047619, Blast_Score=156, Evalue=3e-38,
Organism=Escherichia coli, GI1789786, Length=311, Percent_Identity=27.6527331189711, Blast_Score=66, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI72001474, Length=325, Percent_Identity=28.3076923076923, Blast_Score=140, Evalue=9e-34,
Organism=Saccharomyces cerevisiae, GI6324475, Length=328, Percent_Identity=26.8292682926829, Blast_Score=112, Evalue=6e-26,
Organism=Drosophila melanogaster, GI17864462, Length=332, Percent_Identity=29.2168674698795, Blast_Score=133, Evalue=2e-31,
Organism=Drosophila melanogaster, GI24645295, Length=332, Percent_Identity=29.2168674698795, Blast_Score=133, Evalue=2e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002305
- InterPro:   IPR014729
- InterPro:   IPR002306
- InterPro:   IPR020653 [H]

Pfam domain/function: PF00579 tRNA-synt_1b [H]

EC number: =6.1.1.2 [H]

Molecular weight: Translated: 36605; Mature: 36605

Theoretical pI: Translated: 5.29; Mature: 5.29

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKRGVIFGHRDFDKVNNLINKKEDFAVVGGMMPSGQMHIGHKMVVDQLKWYQDKGAMLSI
CCCCEEECCCCHHHHHHHHCCCCCCEEECCCCCCCCEECHHHHHHHHHHHHHCCCHHHHH
LIADLESYAARDMSFEKARDIAVNEYLTNYIALGLDLEEDNVNVYLQSKNDTLRDLAFKA
HHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCEEEECCCEEEEEECCCCHHHHHHHHH
SKKTNFNELKAIYGFTQSTNIAHIQAPLVQVADILLPQLEEFGGPKRVVVPVGVDQDPHI
CCCCCHHHHHHHHCCCCCCCEEEHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCE
RLTRDIAHKLNDEYGFIPPSSTYHRFLTGLSGDKMSSSKPSTAIYLNEDSETAAKKVKTA
EHHHHHHHHCCCCCCCCCCCHHHHHHHHCCCCCCCCCCCCCEEEEECCCCHHHHHHHHHH
KTGGRESLKEQQELGGQVDNCVIYEMFVYHLIDDDKELEKIRHDCLDGSLRCGDCKAKAS
CCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCCCHHHHHH
ELIVEMFDEIHDKQDEAREIANNLI
HHHHHHHHHHHCCHHHHHHHHHHCC
>Mature Secondary Structure
MKRGVIFGHRDFDKVNNLINKKEDFAVVGGMMPSGQMHIGHKMVVDQLKWYQDKGAMLSI
CCCCEEECCCCHHHHHHHHCCCCCCEEECCCCCCCCEECHHHHHHHHHHHHHCCCHHHHH
LIADLESYAARDMSFEKARDIAVNEYLTNYIALGLDLEEDNVNVYLQSKNDTLRDLAFKA
HHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCEEEECCCEEEEEECCCCHHHHHHHHH
SKKTNFNELKAIYGFTQSTNIAHIQAPLVQVADILLPQLEEFGGPKRVVVPVGVDQDPHI
CCCCCHHHHHHHHCCCCCCCEEEHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCE
RLTRDIAHKLNDEYGFIPPSSTYHRFLTGLSGDKMSSSKPSTAIYLNEDSETAAKKVKTA
EHHHHHHHHCCCCCCCCCCCHHHHHHHHCCCCCCCCCCCCCEEEEECCCCHHHHHHHHHH
KTGGRESLKEQQELGGQVDNCVIYEMFVYHLIDDDKELEKIRHDCLDGSLRCGDCKAKAS
CCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCCCHHHHHH
ELIVEMFDEIHDKQDEAREIANNLI
HHHHHHHHHHHCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9371463 [H]