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The map label for this gene is metX [H]

Identifier: 148642235

GI number: 148642235

Start: 177222

End: 178697

Strand: Reverse

Name: metX [H]

Synonym: Msm_0175

Alternate gene names: 148642235

Gene position: 178697-177222 (Counterclockwise)

Preceding gene: 148642236

Following gene: 148642233

Centisome position: 9.64

GC content: 35.57

Gene sequence:

>1476_bases
ATGAAAAAAGAATCAGTTGGAGTTGTTCAAACAAAGTATTATAATATTGAAGAGCCAATTGAACTAGAAAGTGGAAAGAC
TCTTGATAACATCACAGTAGCTTATGAAACTTATGGTGAGCTTAACAGGGAAAAGGACAATGCAATTTTAATATGTCATG
CATTATCCGGAGATGCACATGCTGCAGGATGGCATGAAGGAGATAAAAAACCTGGATGGTGGGAAATAGTAATAGGTCCC
GGAAAAGCTCTGGATAGTGAAAAGTACTTTATAATCTGTTCTAATGTATTGGGAGGATGTAAAGGAACAACAGGCCCATC
ATCAATCAATCCAAAAACTGGTAAGGAATATGGTATAGATTTTCCGGTTATTACAATAAAGGACATGGTAAATGTTCAAA
AGAAACTGGTTGATGCATTTGGAATTGATAAACTGGCAGCAGTTGTTGGAGGTTCAATGGGAGGAATGCAAACCCTGCAG
TGGATTGTTTCATATCCTGAAATGATGAAAAAAGCAGTTGCAATAGCTACAACAGCAAGATCTTCACCGCAGCAAATAGC
ATTTAATGAAGTGGGCCGCCAATCAATAGTAGGCGATCCGAACTGGAACGGTGGAAACTATTATGGAACTGACAAAATTC
CAAAAGAAGGGTTGTCTGTAGCCCGTATGATAGCTCATATTACTTATTTAAGTGATGAATCAATGTATCTTAAATTTGGT
AGGGATCTGCAGGATAAAGATGAAATTACATATGATTTGTCAATGGATTTCCAGGTTGAAAGCTACCTGCACCATCAGGG
AGCAAGTTTTGTAAAACGTTTTGATGCAAACAGTTATCTCTATATTACAAAAGCAGTGGATTTATTTGACCTTGCCCAAA
ACAACTCTCTGATTGACGGACTTAAAGATGTAAAGGCAAAAGTGGAAATTATTTCAGTGGATTCAGACTGGCTATATCCT
GTTGAACAGGGAACAGAAATCCTGACAGCACTTAATGCAAATGATGTTGAGGTAAGCTTTTCAGAACTTAAATCTAATTA
TGGTCATGATGCATTTTTACTTGAAAAAGGTCAGCTTAACTATATTTTATCAAAATTCTTGTCAGACAACATAGTTGAAG
ACTTGATGATTACTGATGTAGTTACAATTACCGAACAGGCACAGATAGAGGAAGCCGCTAAATTAATGTTTAATCTTAAT
GTTACACATATTCCTGTTGTTACAAATGGCAAAAAGCTGATTGGAATCGTAACTAGCTGGGATTTGTCTAAAGCAATAGC
TACAAATTCCAATGATTTAAAAGAAATAATGACAAAAACAGTTAAATTCTGTCATGCAGACGATTCTATTGAATCAACAG
CACGCAGAATGAGAAAATTGGATATTTCATGTCTTCCTGTTGTAGATGATGACTTTAAATTAAAAGGAATAATCTCTACT
GATCAAATAAGTCATTTAGTATCAGAATATAGGTAG

Upstream 100 bases:

>100_bases
AATGGGTGTTGGTAAAGGTAAAAACAAAAAAGAAGCTGAACAGGCTGCTTCAAAACAGGCTATGAAAAAACTGAAAATAC
AGAAATATTAGGTGTTTTAA

Downstream 100 bases:

>100_bases
AAAGGTAAAAATCCTTTCTAGCTAACTGCTTTTTTTAATGCCTGGTCAATATCAGCTATTAAATCTTCAGCATCCTCAAT
ACCAACAGACATTCTGATAA

Product: homoserine O-acetyltransferase, MetX

Products: NA

Alternate protein names: Homoserine O-trans-acetylase; HTA; Homoserine transacetylase [H]

Number of amino acids: Translated: 491; Mature: 491

Protein sequence:

>491_residues
MKKESVGVVQTKYYNIEEPIELESGKTLDNITVAYETYGELNREKDNAILICHALSGDAHAAGWHEGDKKPGWWEIVIGP
GKALDSEKYFIICSNVLGGCKGTTGPSSINPKTGKEYGIDFPVITIKDMVNVQKKLVDAFGIDKLAAVVGGSMGGMQTLQ
WIVSYPEMMKKAVAIATTARSSPQQIAFNEVGRQSIVGDPNWNGGNYYGTDKIPKEGLSVARMIAHITYLSDESMYLKFG
RDLQDKDEITYDLSMDFQVESYLHHQGASFVKRFDANSYLYITKAVDLFDLAQNNSLIDGLKDVKAKVEIISVDSDWLYP
VEQGTEILTALNANDVEVSFSELKSNYGHDAFLLEKGQLNYILSKFLSDNIVEDLMITDVVTITEQAQIEEAAKLMFNLN
VTHIPVVTNGKKLIGIVTSWDLSKAIATNSNDLKEIMTKTVKFCHADDSIESTARRMRKLDISCLPVVDDDFKLKGIIST
DQISHLVSEYR

Sequences:

>Translated_491_residues
MKKESVGVVQTKYYNIEEPIELESGKTLDNITVAYETYGELNREKDNAILICHALSGDAHAAGWHEGDKKPGWWEIVIGP
GKALDSEKYFIICSNVLGGCKGTTGPSSINPKTGKEYGIDFPVITIKDMVNVQKKLVDAFGIDKLAAVVGGSMGGMQTLQ
WIVSYPEMMKKAVAIATTARSSPQQIAFNEVGRQSIVGDPNWNGGNYYGTDKIPKEGLSVARMIAHITYLSDESMYLKFG
RDLQDKDEITYDLSMDFQVESYLHHQGASFVKRFDANSYLYITKAVDLFDLAQNNSLIDGLKDVKAKVEIISVDSDWLYP
VEQGTEILTALNANDVEVSFSELKSNYGHDAFLLEKGQLNYILSKFLSDNIVEDLMITDVVTITEQAQIEEAAKLMFNLN
VTHIPVVTNGKKLIGIVTSWDLSKAIATNSNDLKEIMTKTVKFCHADDSIESTARRMRKLDISCLPVVDDDFKLKGIIST
DQISHLVSEYR
>Mature_491_residues
MKKESVGVVQTKYYNIEEPIELESGKTLDNITVAYETYGELNREKDNAILICHALSGDAHAAGWHEGDKKPGWWEIVIGP
GKALDSEKYFIICSNVLGGCKGTTGPSSINPKTGKEYGIDFPVITIKDMVNVQKKLVDAFGIDKLAAVVGGSMGGMQTLQ
WIVSYPEMMKKAVAIATTARSSPQQIAFNEVGRQSIVGDPNWNGGNYYGTDKIPKEGLSVARMIAHITYLSDESMYLKFG
RDLQDKDEITYDLSMDFQVESYLHHQGASFVKRFDANSYLYITKAVDLFDLAQNNSLIDGLKDVKAKVEIISVDSDWLYP
VEQGTEILTALNANDVEVSFSELKSNYGHDAFLLEKGQLNYILSKFLSDNIVEDLMITDVVTITEQAQIEEAAKLMFNLN
VTHIPVVTNGKKLIGIVTSWDLSKAIATNSNDLKEIMTKTVKFCHADDSIESTARRMRKLDISCLPVVDDDFKLKGIIST
DQISHLVSEYR

Specific function: Unknown

COG id: COG2021

COG function: function code E; Homoserine acetyltransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the AB hydrolase superfamily. HTA family [H]

Homologues:

Organism=Saccharomyces cerevisiae, GI6324052, Length=221, Percent_Identity=42.5339366515837, Blast_Score=182, Evalue=8e-47,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000073
- InterPro:   IPR008220 [H]

Pfam domain/function: PF00561 Abhydrolase_1 [H]

EC number: =2.3.1.31 [H]

Molecular weight: Translated: 54523; Mature: 54523

Theoretical pI: Translated: 4.81; Mature: 4.81

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKESVGVVQTKYYNIEEPIELESGKTLDNITVAYETYGELNREKDNAILICHALSGDAH
CCCCCCCEEEEEEECCCCCEECCCCCCCCCEEEEEECHHCCCCCCCCEEEEEEEECCCCC
AAGWHEGDKKPGWWEIVIGPGKALDSEKYFIICSNVLGGCKGTTGPSSINPKTGKEYGID
CCCCCCCCCCCCEEEEEECCCCCCCCCCEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCC
FPVITIKDMVNVQKKLVDAFGIDKLAAVVGGSMGGMQTLQWIVSYPEMMKKAVAIATTAR
CCEEEHHHHHHHHHHHHHHHCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHECCC
SSPQQIAFNEVGRQSIVGDPNWNGGNYYGTDKIPKEGLSVARMIAHITYLSDESMYLKFG
CCCHHHHHHHCCCHHCCCCCCCCCCCEECCCCCCHHHHHHHHHHHHHHEECCCCEEEEEC
RDLQDKDEITYDLSMDFQVESYLHHQGASFVKRFDANSYLYITKAVDLFDLAQNNSLIDG
CCCCCCCCEEEEEEECEEHHHHHHHCCHHHHHHHCCCCEEEEEECCHHHHHHCCCCHHHH
LKDVKAKVEIISVDSDWLYPVEQGTEILTALNANDVEVSFSELKSNYGHDAFLLEKGQLN
HHHCEEEEEEEEECCCCCCCHHCCCEEEEEECCCCCEEEHHHHHHCCCCCEEEEECCCHH
YILSKFLSDNIVEDLMITDVVTITEQAQIEEAAKLMFNLNVTHIPVVTNGKKLIGIVTSW
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCEEEEEEECCCEEEEEEECC
DLSKAIATNSNDLKEIMTKTVKFCHADDSIESTARRMRKLDISCLPVVDDDFKLKGIIST
CCHHHHHCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCEEEEEECCCCEEEEEECH
DQISHLVSEYR
HHHHHHHHHCC
>Mature Secondary Structure
MKKESVGVVQTKYYNIEEPIELESGKTLDNITVAYETYGELNREKDNAILICHALSGDAH
CCCCCCCEEEEEEECCCCCEECCCCCCCCCEEEEEECHHCCCCCCCCEEEEEEEECCCCC
AAGWHEGDKKPGWWEIVIGPGKALDSEKYFIICSNVLGGCKGTTGPSSINPKTGKEYGID
CCCCCCCCCCCCEEEEEECCCCCCCCCCEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCC
FPVITIKDMVNVQKKLVDAFGIDKLAAVVGGSMGGMQTLQWIVSYPEMMKKAVAIATTAR
CCEEEHHHHHHHHHHHHHHHCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHECCC
SSPQQIAFNEVGRQSIVGDPNWNGGNYYGTDKIPKEGLSVARMIAHITYLSDESMYLKFG
CCCHHHHHHHCCCHHCCCCCCCCCCCEECCCCCCHHHHHHHHHHHHHHEECCCCEEEEEC
RDLQDKDEITYDLSMDFQVESYLHHQGASFVKRFDANSYLYITKAVDLFDLAQNNSLIDG
CCCCCCCCEEEEEEECEEHHHHHHHCCHHHHHHHCCCCEEEEEECCHHHHHHCCCCHHHH
LKDVKAKVEIISVDSDWLYPVEQGTEILTALNANDVEVSFSELKSNYGHDAFLLEKGQLN
HHHCEEEEEEEEECCCCCCCHHCCCEEEEEECCCCCEEEHHHHHHCCCCCEEEEECCCHH
YILSKFLSDNIVEDLMITDVVTITEQAQIEEAAKLMFNLNVTHIPVVTNGKKLIGIVTSW
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCEEEEEEECCCEEEEEEECC
DLSKAIATNSNDLKEIMTKTVKFCHADDSIESTARRMRKLDISCLPVVDDDFKLKGIIST
CCHHHHHCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCEEEEEECCCCEEEEEECH
DQISHLVSEYR
HHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA