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The map label for this gene is yprA [H]

Identifier: 148642172

GI number: 148642172

Start: 104809

End: 107409

Strand: Reverse

Name: yprA [H]

Synonym: Msm_0112

Alternate gene names: 148642172

Gene position: 107409-104809 (Counterclockwise)

Preceding gene: 148642176

Following gene: 148642171

Centisome position: 5.8

GC content: 32.41

Gene sequence:

>2601_bases
ATGACCAAATCAACAATTGATATGTTTAAAAATGATGTGAGGTACAGGGACAGAATAGCTCATGTAGAAACTATTCCTGC
CAGAAAAGCTAGCTATAAAAAAGTTGATAATTTAAATCCTAAAATTGTTGATTATTTAAAGTCAAAAAATGCTAAATTAT
ATAAACATCAATCAGAAACTTATGAGGCCATTCAAAATGATGAAAATGTAATCATTACAACACCTACAGCTTCAGGTAAA
ACATTGGCTTTCAATTTGCCGATTATGGAAACAATGATTGAAGATGAAGATGCCACAGCATTATATATTTACCCTGCAAA
GGCTCTCTCAAACGATCAGCTCCATGTTTTGGAAAATCTTGAAAAATCCCTGGACATTAAAATTAATCCTAATACATATG
ACGGGGATACTCCAAAATCCAAAAGATATGATATTCGTCAAAAATCAAGGATTATTCTAACAAATCCCTATCAGCTGCAT
CTTATTCTGTCCTGGCATCACCAGTGGAAACGTTTTTACAGCAATCTGAAATTCATTGTCATTGATGAATCCCATTATTA
TAAGGGTATTTTCGGCTCAAATGTGGCTTATCTTATTCGAAGACTAAAAAGAATAGCTAATTTCTACGGAGCAAATCCTC
AGTTTATATTATCTTCTGCAACATTGGCCAATCCATTGGAACTGGCTAACAGATTAACAGGTGAGAAGTTCAGATTAGTG
GATAATGATACATCTCCAAGCGGAGAAAAAGATTTTATATTGTACAATCCATTCAGAAATTACAGAAGAAAAAAACACAA
CAGTGAAGAGGCACCTTCTGTACACATTGAAACAGAAAATATATTTGTTTACCTGATGTTAAAAGACATTCAAACATTAT
GTTTTACTGTTTCACGTAAAATAACTGAATTAATAGCTATGTGGGCTAAAAAAGACATGGATAATATTAAGAAAAAATTG
ACCCACAGAATAACTGCATATAGGGCAGGTTATCAGGCAGATGAAAGACGTGAAATTGAGGACGGATTGAAATCACGTAA
ATATCTTGGAGTTACATGTACAAATGCTTTGGAATTAGGTATCAATATAGGTTCACTTGATGCAGTTATTATTTCAGGAT
ATCCCGGAACTATGATTTCCACATGGCAGCAAAGCGGAAGGGCAGGCAGAAGCAATCAGAAATCATTAGCTATTTTGGTT
GCCTTTGAAAATCAGCTAGATCAGTATTTTATGAATAATCCTGATTTCTTTTTTGATAAACCTCATGAAAATGTAATAAT
TGATTTGTCAAACCATATATTGCAGGAAGCCCATTTATTGTGTGCCGCTAAAGAATTAACTCTTAAAAAAGATGAAGCTA
TGGATTATTTTGGAGTGGATAAAGAAGTCTTGGGCAAATTGGTTTCTAAAAAGGATTTATATCAAAATCCCCGTGGAGAT
TATATTTACCCATATGATGACAATCCTGCAATGTCACATTCTCTTGATCAGTTATCCAATGATGAATTCAGAGTAATGAA
TAATGGTAAACTTTTAGAGGTTATGGAACGCTCACAGGTTTATAGGGAAGCACATGAAGGAGCTATTTTAATTAATAAAG
GTGAAACATATCAGGTAGACAGTGTTAATTTAGCCAGTCATTTTGTAAATGTTTCTAAAAACACTGTAGATTATCATACC
ATGGTTTTAAATAAGGTACATATCAATATTGAGAAAAAATTATCCAAAACAAAATACGGCAATTTAAAAATCCATTTCGG
TGAATTAACTGTAGAGGAAGACTATTACAGATATAAGAAAATGCATTTTTCAAAAGTAATCGGACAGTTTAATTTAGATT
TGCCACCTTTAAAATTCAGAACAAAAGGATTATGGTTTACAGTTCCACGTGAAGTTAAAAATAATCTTGAAGATTTATAT
AAAGGTGAAGAGGAAGTCTTTGAAGGTGGACTTCACGGTGCGGAACATGCATTAATAGGTTTGTTTCCGCTTCATGTAAT
GTGTGACAGATTTGACATTGGAGGATTATCTACAAATTATCATGAAGACACTCAGGAAGCTACAATATTCATTTATGATG
CTTATGAAGGTGGAATTGGAATAACACAAAAAGCTGTTGATGTATTTGTTGATTTGTTAAAATCTACAAGAGATTTGCTT
AAAAATTGTAGCTGTCATGACGGATGCCCTTCATGTATTTATTCTCCGAAATGCGGAAATGATAATAAGCCACTTCACAA
AAAAGCAACTGAATATATTTTAAATTATATGTGCAATCTGATTTCACAAAATCCTGAAGAAACAGCTATTGAAAAAGTTG
AGGAAAATGAAATTGAAGAGATTTCTACTAATGATATAACTCTTGAAACATTATATGAAGAAGCTTATGATTTATATTCA
CAAGGAGATTATTTCAACTCAAAAGAATCATTAAATGAGCTGGTTGAAATTGATGATGAATATGCTGATGCATGGGCTTT
ATTTGGTAGAATATTATATGAACAGGGTGACAGAAATGGAGCCAAAATGTTTACAAAAAGGGCTCTAAAAATTGACTCTG
CCAACGAAGATGCTAATGAATTATGGTTAGAATTAAAATAA

Upstream 100 bases:

>100_bases
CTCTACAGAGCATTTGATAAGTATCATTTACACGAATAATTTAAATATTTAATTTATTCATATATTATTTATTAATGGAT
AACTTTTTTTCAAGATTATT

Downstream 100 bases:

>100_bases
TTTATTTTATTTTTCTTCGTTTAACCTATTACATTTTTTTTGAATATTAAATGGAAATACAGTAGGAAACTTTAAATATT
TTCAATGTTAATATATAACG

Product: EIF-4a family ATP-dependent RNA helicase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 866; Mature: 865

Protein sequence:

>866_residues
MTKSTIDMFKNDVRYRDRIAHVETIPARKASYKKVDNLNPKIVDYLKSKNAKLYKHQSETYEAIQNDENVIITTPTASGK
TLAFNLPIMETMIEDEDATALYIYPAKALSNDQLHVLENLEKSLDIKINPNTYDGDTPKSKRYDIRQKSRIILTNPYQLH
LILSWHHQWKRFYSNLKFIVIDESHYYKGIFGSNVAYLIRRLKRIANFYGANPQFILSSATLANPLELANRLTGEKFRLV
DNDTSPSGEKDFILYNPFRNYRRKKHNSEEAPSVHIETENIFVYLMLKDIQTLCFTVSRKITELIAMWAKKDMDNIKKKL
THRITAYRAGYQADERREIEDGLKSRKYLGVTCTNALELGINIGSLDAVIISGYPGTMISTWQQSGRAGRSNQKSLAILV
AFENQLDQYFMNNPDFFFDKPHENVIIDLSNHILQEAHLLCAAKELTLKKDEAMDYFGVDKEVLGKLVSKKDLYQNPRGD
YIYPYDDNPAMSHSLDQLSNDEFRVMNNGKLLEVMERSQVYREAHEGAILINKGETYQVDSVNLASHFVNVSKNTVDYHT
MVLNKVHINIEKKLSKTKYGNLKIHFGELTVEEDYYRYKKMHFSKVIGQFNLDLPPLKFRTKGLWFTVPREVKNNLEDLY
KGEEEVFEGGLHGAEHALIGLFPLHVMCDRFDIGGLSTNYHEDTQEATIFIYDAYEGGIGITQKAVDVFVDLLKSTRDLL
KNCSCHDGCPSCIYSPKCGNDNKPLHKKATEYILNYMCNLISQNPEETAIEKVEENEIEEISTNDITLETLYEEAYDLYS
QGDYFNSKESLNELVEIDDEYADAWALFGRILYEQGDRNGAKMFTKRALKIDSANEDANELWLELK

Sequences:

>Translated_866_residues
MTKSTIDMFKNDVRYRDRIAHVETIPARKASYKKVDNLNPKIVDYLKSKNAKLYKHQSETYEAIQNDENVIITTPTASGK
TLAFNLPIMETMIEDEDATALYIYPAKALSNDQLHVLENLEKSLDIKINPNTYDGDTPKSKRYDIRQKSRIILTNPYQLH
LILSWHHQWKRFYSNLKFIVIDESHYYKGIFGSNVAYLIRRLKRIANFYGANPQFILSSATLANPLELANRLTGEKFRLV
DNDTSPSGEKDFILYNPFRNYRRKKHNSEEAPSVHIETENIFVYLMLKDIQTLCFTVSRKITELIAMWAKKDMDNIKKKL
THRITAYRAGYQADERREIEDGLKSRKYLGVTCTNALELGINIGSLDAVIISGYPGTMISTWQQSGRAGRSNQKSLAILV
AFENQLDQYFMNNPDFFFDKPHENVIIDLSNHILQEAHLLCAAKELTLKKDEAMDYFGVDKEVLGKLVSKKDLYQNPRGD
YIYPYDDNPAMSHSLDQLSNDEFRVMNNGKLLEVMERSQVYREAHEGAILINKGETYQVDSVNLASHFVNVSKNTVDYHT
MVLNKVHINIEKKLSKTKYGNLKIHFGELTVEEDYYRYKKMHFSKVIGQFNLDLPPLKFRTKGLWFTVPREVKNNLEDLY
KGEEEVFEGGLHGAEHALIGLFPLHVMCDRFDIGGLSTNYHEDTQEATIFIYDAYEGGIGITQKAVDVFVDLLKSTRDLL
KNCSCHDGCPSCIYSPKCGNDNKPLHKKATEYILNYMCNLISQNPEETAIEKVEENEIEEISTNDITLETLYEEAYDLYS
QGDYFNSKESLNELVEIDDEYADAWALFGRILYEQGDRNGAKMFTKRALKIDSANEDANELWLELK
>Mature_865_residues
TKSTIDMFKNDVRYRDRIAHVETIPARKASYKKVDNLNPKIVDYLKSKNAKLYKHQSETYEAIQNDENVIITTPTASGKT
LAFNLPIMETMIEDEDATALYIYPAKALSNDQLHVLENLEKSLDIKINPNTYDGDTPKSKRYDIRQKSRIILTNPYQLHL
ILSWHHQWKRFYSNLKFIVIDESHYYKGIFGSNVAYLIRRLKRIANFYGANPQFILSSATLANPLELANRLTGEKFRLVD
NDTSPSGEKDFILYNPFRNYRRKKHNSEEAPSVHIETENIFVYLMLKDIQTLCFTVSRKITELIAMWAKKDMDNIKKKLT
HRITAYRAGYQADERREIEDGLKSRKYLGVTCTNALELGINIGSLDAVIISGYPGTMISTWQQSGRAGRSNQKSLAILVA
FENQLDQYFMNNPDFFFDKPHENVIIDLSNHILQEAHLLCAAKELTLKKDEAMDYFGVDKEVLGKLVSKKDLYQNPRGDY
IYPYDDNPAMSHSLDQLSNDEFRVMNNGKLLEVMERSQVYREAHEGAILINKGETYQVDSVNLASHFVNVSKNTVDYHTM
VLNKVHINIEKKLSKTKYGNLKIHFGELTVEEDYYRYKKMHFSKVIGQFNLDLPPLKFRTKGLWFTVPREVKNNLEDLYK
GEEEVFEGGLHGAEHALIGLFPLHVMCDRFDIGGLSTNYHEDTQEATIFIYDAYEGGIGITQKAVDVFVDLLKSTRDLLK
NCSCHDGCPSCIYSPKCGNDNKPLHKKATEYILNYMCNLISQNPEETAIEKVEENEIEEISTNDITLETLYEEAYDLYSQ
GDYFNSKESLNELVEIDDEYADAWALFGRILYEQGDRNGAKMFTKRALKIDSANEDANELWLELK

Specific function: Unknown

COG id: COG1205

COG function: function code R; Distinct helicase family with a unique C-terminal domain including a metal-binding cysteine cluster

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 helicase C-terminal domain [H]

Homologues:

Organism=Saccharomyces cerevisiae, GI6320497, Length=822, Percent_Identity=30.6569343065693, Blast_Score=372, Evalue=1e-103,
Organism=Saccharomyces cerevisiae, GI9755332, Length=184, Percent_Identity=29.3478260869565, Blast_Score=67, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014001
- InterPro:   IPR018973
- InterPro:   IPR011545
- InterPro:   IPR001650
- InterPro:   IPR014021 [H]

Pfam domain/function: PF00270 DEAD; PF09369 DUF1998; PF00271 Helicase_C [H]

EC number: 3.6.1.- [C]

Molecular weight: Translated: 99841; Mature: 99710

Theoretical pI: Translated: 6.14; Mature: 6.14

Prosite motif: PS50005 TPR L=RR ; PS50293 TPR_REGION

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKSTIDMFKNDVRYRDRIAHVETIPARKASYKKVDNLNPKIVDYLKSKNAKLYKHQSET
CCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHCCCCHHHHHHHHCCCCEEEECCHHH
YEAIQNDENVIITTPTASGKTLAFNLPIMETMIEDEDATALYIYPAKALSNDQLHVLENL
HHHHCCCCCEEEECCCCCCCEEEEECCHHHHHHCCCCCCEEEEEEHHHCCCCCHHHHHHH
EKSLDIKINPNTYDGDTPKSKRYDIRQKSRIILTNPYQLHLILSWHHQWKRFYSNLKFIV
HHCEEEEECCCCCCCCCCCCCCCCCCCCCEEEEECCEEEEEEEEHHHHHHHHHCCCEEEE
IDESHYYKGIFGSNVAYLIRRLKRIANFYGANPQFILSSATLANPLELANRLTGEKFRLV
EECCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCEEEECCCCCCHHHHHHHCCCCEEEEE
DNDTSPSGEKDFILYNPFRNYRRKKHNSEEAPSVHIETENIFVYLMLKDIQTLCFTVSRK
ECCCCCCCCCCEEEECCHHHHHHHCCCCCCCCEEEEEECCEEEEEEHHHHHHHHHHHHHH
ITELIAMWAKKDMDNIKKKLTHRITAYRAGYQADERREIEDGLKSRKYLGVTCTNALELG
HHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCEEEEEEECCCEEEC
INIGSLDAVIISGYPGTMISTWQQSGRAGRSNQKSLAILVAFENQLDQYFMNNPDFFFDK
CEECCCCEEEEECCCCHHHHHHHHCCCCCCCCCCEEEEEEEECHHHHHHHCCCCCCEEEC
PHENVIIDLSNHILQEAHLLCAAKELTLKKDEAMDYFGVDKEVLGKLVSKKDLYQNPRGD
CCCCEEEECHHHHHHHHHHHHHHHHHHCCCHHCCHHCCCCHHHHHHHHHHHHHHCCCCCC
YIYPYDDNPAMSHSLDQLSNDEFRVMNNGKLLEVMERSQVYREAHEGAILINKGETYQVD
EEEECCCCCHHHHHHHHCCCCCEEEECCCCHHHHHHHHHHHHHHCCCEEEEECCCEEEEC
SVNLASHFVNVSKNTVDYHTMVLNKVHINIEKKLSKTKYGNLKIHFGELTVEEDYYRYKK
CCHHHHHHHHCCCCCCCHHEEEEEEEEEEHHHHHHHCCCCCEEEEEEEEEECHHHHHHHH
MHFSKVIGQFNLDLPPLKFRTKGLWFTVPREVKNNLEDLYKGEEEVFEGGLHGAEHALIG
HHHHHHHHHCCCCCCCCEEEECCEEEEECHHHHCCHHHHHCCHHHHHHCCCCCHHHHHHH
LFPLHVMCDRFDIGGLSTNYHEDTQEATIFIYDAYEGGIGITQKAVDVFVDLLKSTRDLL
HHHHHHHHCCCCCCCCCCCCCCCCCCEEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHH
KNCSCHDGCPSCIYSPKCGNDNKPLHKKATEYILNYMCNLISQNPEETAIEKVEENEIEE
HCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHH
ISTNDITLETLYEEAYDLYSQGDYFNSKESLNELVEIDDEYADAWALFGRILYEQGDRNG
CCCCCEEHHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCH
AKMFTKRALKIDSANEDANELWLELK
HHHHHHHHHEECCCCCCCHHEEEEEC
>Mature Secondary Structure 
TKSTIDMFKNDVRYRDRIAHVETIPARKASYKKVDNLNPKIVDYLKSKNAKLYKHQSET
CCHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHCCCCHHHHHHHHCCCCEEEECCHHH
YEAIQNDENVIITTPTASGKTLAFNLPIMETMIEDEDATALYIYPAKALSNDQLHVLENL
HHHHCCCCCEEEECCCCCCCEEEEECCHHHHHHCCCCCCEEEEEEHHHCCCCCHHHHHHH
EKSLDIKINPNTYDGDTPKSKRYDIRQKSRIILTNPYQLHLILSWHHQWKRFYSNLKFIV
HHCEEEEECCCCCCCCCCCCCCCCCCCCCEEEEECCEEEEEEEEHHHHHHHHHCCCEEEE
IDESHYYKGIFGSNVAYLIRRLKRIANFYGANPQFILSSATLANPLELANRLTGEKFRLV
EECCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCEEEECCCCCCHHHHHHHCCCCEEEEE
DNDTSPSGEKDFILYNPFRNYRRKKHNSEEAPSVHIETENIFVYLMLKDIQTLCFTVSRK
ECCCCCCCCCCEEEECCHHHHHHHCCCCCCCCEEEEEECCEEEEEEHHHHHHHHHHHHHH
ITELIAMWAKKDMDNIKKKLTHRITAYRAGYQADERREIEDGLKSRKYLGVTCTNALELG
HHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCEEEEEEECCCEEEC
INIGSLDAVIISGYPGTMISTWQQSGRAGRSNQKSLAILVAFENQLDQYFMNNPDFFFDK
CEECCCCEEEEECCCCHHHHHHHHCCCCCCCCCCEEEEEEEECHHHHHHHCCCCCCEEEC
PHENVIIDLSNHILQEAHLLCAAKELTLKKDEAMDYFGVDKEVLGKLVSKKDLYQNPRGD
CCCCEEEECHHHHHHHHHHHHHHHHHHCCCHHCCHHCCCCHHHHHHHHHHHHHHCCCCCC
YIYPYDDNPAMSHSLDQLSNDEFRVMNNGKLLEVMERSQVYREAHEGAILINKGETYQVD
EEEECCCCCHHHHHHHHCCCCCEEEECCCCHHHHHHHHHHHHHHCCCEEEEECCCEEEEC
SVNLASHFVNVSKNTVDYHTMVLNKVHINIEKKLSKTKYGNLKIHFGELTVEEDYYRYKK
CCHHHHHHHHCCCCCCCHHEEEEEEEEEEHHHHHHHCCCCCEEEEEEEEEECHHHHHHHH
MHFSKVIGQFNLDLPPLKFRTKGLWFTVPREVKNNLEDLYKGEEEVFEGGLHGAEHALIG
HHHHHHHHHCCCCCCCCEEEECCEEEEECHHHHCCHHHHHCCHHHHHHCCCCCHHHHHHH
LFPLHVMCDRFDIGGLSTNYHEDTQEATIFIYDAYEGGIGITQKAVDVFVDLLKSTRDLL
HHHHHHHHCCCCCCCCCCCCCCCCCCEEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHH
KNCSCHDGCPSCIYSPKCGNDNKPLHKKATEYILNYMCNLISQNPEETAIEKVEENEIEE
HCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHH
ISTNDITLETLYEEAYDLYSQGDYFNSKESLNELVEIDDEYADAWALFGRILYEQGDRNG
CCCCCEEHHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCH
AKMFTKRALKIDSANEDANELWLELK
HHHHHHHHHEECCCCCCCHHEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on acid anhydrides [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8760912; 9384377 [H]