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The map label for this gene is xseA [H]

Identifier: 148642061

GI number: 148642061

Start: 114

End: 1697

Strand: Reverse

Name: xseA [H]

Synonym: Msm_0001

Alternate gene names: 148642061

Gene position: 1697-114 (Counterclockwise)

Preceding gene: 148642063

Following gene: NA

Centisome position: 0.09

GC content: 28.16

Gene sequence:

>1584_bases
ATGGAAGAAAATGATATTTACTCAATCAGTGCAATCAATAATTTGATTGATAAAAAAATTAGCTACTGTGATGATTTTAA
AAAGATTAAAATCAGAGGTGAAATAACTAATTTTAACGGATCATATAATTCAGGACACTACTATTTCTCCCTAAAAGACA
AAAACTCTTCAATTTCCTGTGTAATGTTTAAATTATCTACAAAATCTTTGGATTTTGAACCTAAAAATGGTGTGGATGTT
GTAGCCAGTGGTGAAGTTTCATTTTATAAAGTACGTGGAAACCTGCAATTCAGAGTAAGAAAAATGCAGGAAGCAGGATT
GGGAGATTTATACATTGCTTTTGAAAAGCTTAAAAAGAAATTAGATAAAGAAGGATTATTTAAAGACAAAAAAGTAATTC
CACAATATCCTAAAAAAATAGGAGTAATAACCTCTGCAAGCGGAAAAGCCGTTAAAGACATTGTAAACAACATTGAAAAA
AGATGGCCTGCAGAAATAATTGTCTGGAACACTACAGTACAGGGAGCCAACTCTACCCGAAGCATAACTAAAAATATTGC
ACTGGCAAACAAAACAGATGTTGATGTGATAATTGTAGGTCGTGGAGGAGGAAGTACTCAGGATTTATGGGATTTTAACA
AAGAGGAAATTGTACGTTCAATAGCTAATTCTAAAAAACCGGTTATAACAGCTATTGGTCACTCAACAGACAAAACGCTT
TCAGACATGGTATCCGATAAAGTTGCAGCAACACCCACAAAAGCAGCTGAGCTGGTTGTTCCAAATAAAGTTGAACTTAA
TGAAAAACTAAAAAATATTGAAACAAGATTAAATGATTTGATAAATTCCAAATTAGATAATTTAACACATAAACTCAATA
TTTCCAAAAACAATAAAACCTTAAAAGATCCTTTATCAAAGTATAAGAATCATCAAACAAATTTAGTTTTATTAAAAACA
ACTGCTGAGAAATCATTAAATCAGCTGATTCAGTCAAATGAACTGCAGCTTGATAACTTTAATAATTCATATATTCTGAA
TAATCCGGATTATATTTTAAATAAAAAAGTCGGTAAAATTACTTTATTTAAAAATGAATTGGATAATAACATGTCTAACT
GTCTGTTAGAATATGAAAATAAACTTAACCTGCACTTTAAAAATTTGAAATCCATGAATTTCATTGAATCTTTTGAATTA
AAAAAAAATTCTTTAAATTTAATTGAGAATAATTTAAATAATTCAATTAATGTCACATTGAATTCGCATATTCATGATTT
GGAAATAATTAAAAATAATCATGTTTTCAGCAATCCGTGTCAGGTATTGGACGATAAATTTGTTAAAATGGCTCAAATAC
ATAAAAGTTTAGATGCAGAAATTACCAAGACATTAGACAGTAATGAAAATAAATTAAGGATTCTTGAAGAAAAATTAAAG
ATTTTAAATCCTGATGAATTGCTGGAAAAGGGATATGTTGTAAAAGATCCTGATGAAATAAGAAAATCCAAAGCTAAAAA
TGTAATTATAGTACTGTTTTTAGCTATTGTTATAGTACTGTTAATATTACTTAGTTTAAAATAA

Upstream 100 bases:

>100_bases
TTTAGTTGACACAATTAAATAACAATGATTAAATCAGATTAATGATAAAACATTATTACAAATTAAATTCAATATTAAAT
TTAACCTGCATGGTGTTTTG

Downstream 100 bases:

>100_bases
AATAAAAGGTGATAATATGACTAAAAGTTTTGAAGAAAAGTTAGAAGAATTGGAAAAATTAGTTAAGCAATTAGAATCAG
ATAATGTTCCGTTAAAAGAA

Product: exoribonuclease VII, large subunit, XseA

Products: NA

Alternate protein names: Exodeoxyribonuclease VII large subunit; Exonuclease VII large subunit [H]

Number of amino acids: Translated: 527; Mature: 527

Protein sequence:

>527_residues
MEENDIYSISAINNLIDKKISYCDDFKKIKIRGEITNFNGSYNSGHYYFSLKDKNSSISCVMFKLSTKSLDFEPKNGVDV
VASGEVSFYKVRGNLQFRVRKMQEAGLGDLYIAFEKLKKKLDKEGLFKDKKVIPQYPKKIGVITSASGKAVKDIVNNIEK
RWPAEIIVWNTTVQGANSTRSITKNIALANKTDVDVIIVGRGGGSTQDLWDFNKEEIVRSIANSKKPVITAIGHSTDKTL
SDMVSDKVAATPTKAAELVVPNKVELNEKLKNIETRLNDLINSKLDNLTHKLNISKNNKTLKDPLSKYKNHQTNLVLLKT
TAEKSLNQLIQSNELQLDNFNNSYILNNPDYILNKKVGKITLFKNELDNNMSNCLLEYENKLNLHFKNLKSMNFIESFEL
KKNSLNLIENNLNNSINVTLNSHIHDLEIIKNNHVFSNPCQVLDDKFVKMAQIHKSLDAEITKTLDSNENKLRILEEKLK
ILNPDELLEKGYVVKDPDEIRKSKAKNVIIVLFLAIVIVLLILLSLK

Sequences:

>Translated_527_residues
MEENDIYSISAINNLIDKKISYCDDFKKIKIRGEITNFNGSYNSGHYYFSLKDKNSSISCVMFKLSTKSLDFEPKNGVDV
VASGEVSFYKVRGNLQFRVRKMQEAGLGDLYIAFEKLKKKLDKEGLFKDKKVIPQYPKKIGVITSASGKAVKDIVNNIEK
RWPAEIIVWNTTVQGANSTRSITKNIALANKTDVDVIIVGRGGGSTQDLWDFNKEEIVRSIANSKKPVITAIGHSTDKTL
SDMVSDKVAATPTKAAELVVPNKVELNEKLKNIETRLNDLINSKLDNLTHKLNISKNNKTLKDPLSKYKNHQTNLVLLKT
TAEKSLNQLIQSNELQLDNFNNSYILNNPDYILNKKVGKITLFKNELDNNMSNCLLEYENKLNLHFKNLKSMNFIESFEL
KKNSLNLIENNLNNSINVTLNSHIHDLEIIKNNHVFSNPCQVLDDKFVKMAQIHKSLDAEITKTLDSNENKLRILEEKLK
ILNPDELLEKGYVVKDPDEIRKSKAKNVIIVLFLAIVIVLLILLSLK
>Mature_527_residues
MEENDIYSISAINNLIDKKISYCDDFKKIKIRGEITNFNGSYNSGHYYFSLKDKNSSISCVMFKLSTKSLDFEPKNGVDV
VASGEVSFYKVRGNLQFRVRKMQEAGLGDLYIAFEKLKKKLDKEGLFKDKKVIPQYPKKIGVITSASGKAVKDIVNNIEK
RWPAEIIVWNTTVQGANSTRSITKNIALANKTDVDVIIVGRGGGSTQDLWDFNKEEIVRSIANSKKPVITAIGHSTDKTL
SDMVSDKVAATPTKAAELVVPNKVELNEKLKNIETRLNDLINSKLDNLTHKLNISKNNKTLKDPLSKYKNHQTNLVLLKT
TAEKSLNQLIQSNELQLDNFNNSYILNNPDYILNKKVGKITLFKNELDNNMSNCLLEYENKLNLHFKNLKSMNFIESFEL
KKNSLNLIENNLNNSINVTLNSHIHDLEIIKNNHVFSNPCQVLDDKFVKMAQIHKSLDAEITKTLDSNENKLRILEEKLK
ILNPDELLEKGYVVKDPDEIRKSKAKNVIIVLFLAIVIVLLILLSLK

Specific function: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides [H]

COG id: COG1570

COG function: function code L; Exonuclease VII, large subunit

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the xseA family [H]

Homologues:

Organism=Escherichia coli, GI1788856, Length=318, Percent_Identity=37.1069182389937, Blast_Score=225, Evalue=5e-60,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003753
- InterPro:   IPR020579
- InterPro:   IPR004365 [H]

Pfam domain/function: PF02601 Exonuc_VII_L; PF01336 tRNA_anti [H]

EC number: =3.1.11.6 [H]

Molecular weight: Translated: 59759; Mature: 59759

Theoretical pI: Translated: 9.79; Mature: 9.79

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEENDIYSISAINNLIDKKISYCDDFKKIKIRGEITNFNGSYNSGHYYFSLKDKNSSISC
CCCCCEEEHHHHHHHHHHHHHHCCCCEEEEEEEEEEECCCCCCCCEEEEEEECCCCCEEE
VMFKLSTKSLDFEPKNGVDVVASGEVSFYKVRGNLQFRVRKMQEAGLGDLYIAFEKLKKK
EEEEEECCCCCCCCCCCCEEEEECCEEEEEEECCEEEEEEHHHHCCCCHHHHHHHHHHHH
LDKEGLFKDKKVIPQYPKKIGVITSASGKAVKDIVNNIEKRWPAEIIVWNTTVQGANSTR
HCCCCCCCCCCCCCCCHHHEEEEECCCCHHHHHHHHHHHHHCCCEEEEEEEEECCCCCHH
SITKNIALANKTDVDVIIVGRGGGSTQDLWDFNKEEIVRSIANSKKPVITAIGHSTDKTL
HHHHHEEECCCCCEEEEEEECCCCCCCHHHCCCHHHHHHHHHCCCCCEEEEECCCCHHHH
SDMVSDKVAATPTKAAELVVPNKVELNEKLKNIETRLNDLINSKLDNLTHKLNISKNNKT
HHHHHHHHCCCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHEEEEEECCCCCH
LKDPLSKYKNHQTNLVLLKTTAEKSLNQLIQSNELQLDNFNNSYILNNPDYILNKKVGKI
HHHHHHHHCCCCCCEEEEEECHHHHHHHHHHCCCEEEECCCCCEEECCCCEEECCCCCEE
TLFKNELDNNMSNCLLEYENKLNLHFKNLKSMNFIESFELKKNSLNLIENNLNNSINVTL
EEEHHHHCCCHHHHHHHCCCCCEEEEECCCCCCHHHHHHHCCCCHHHHHHCCCCEEEEEE
NSHIHDLEIIKNNHVFSNPCQVLDDKFVKMAQIHKSLDAEITKTLDSNENKLRILEEKLK
CCCCEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHH
ILNPDELLEKGYVVKDPDEIRKSKAKNVIIVLFLAIVIVLLILLSLK
HCCHHHHHHCCCEECCHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MEENDIYSISAINNLIDKKISYCDDFKKIKIRGEITNFNGSYNSGHYYFSLKDKNSSISC
CCCCCEEEHHHHHHHHHHHHHHCCCCEEEEEEEEEEECCCCCCCCEEEEEEECCCCCEEE
VMFKLSTKSLDFEPKNGVDVVASGEVSFYKVRGNLQFRVRKMQEAGLGDLYIAFEKLKKK
EEEEEECCCCCCCCCCCCEEEEECCEEEEEEECCEEEEEEHHHHCCCCHHHHHHHHHHHH
LDKEGLFKDKKVIPQYPKKIGVITSASGKAVKDIVNNIEKRWPAEIIVWNTTVQGANSTR
HCCCCCCCCCCCCCCCHHHEEEEECCCCHHHHHHHHHHHHHCCCEEEEEEEEECCCCCHH
SITKNIALANKTDVDVIIVGRGGGSTQDLWDFNKEEIVRSIANSKKPVITAIGHSTDKTL
HHHHHEEECCCCCEEEEEEECCCCCCCHHHCCCHHHHHHHHHCCCCCEEEEECCCCHHHH
SDMVSDKVAATPTKAAELVVPNKVELNEKLKNIETRLNDLINSKLDNLTHKLNISKNNKT
HHHHHHHHCCCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHEEEEEECCCCCH
LKDPLSKYKNHQTNLVLLKTTAEKSLNQLIQSNELQLDNFNNSYILNNPDYILNKKVGKI
HHHHHHHHCCCCCCEEEEEECHHHHHHHHHHCCCEEEECCCCCEEECCCCEEECCCCCEE
TLFKNELDNNMSNCLLEYENKLNLHFKNLKSMNFIESFELKKNSLNLIENNLNNSINVTL
EEEHHHHCCCHHHHHHHCCCCCEEEEECCCCCCHHHHHHHCCCCHHHHHHCCCCEEEEEE
NSHIHDLEIIKNNHVFSNPCQVLDDKFVKMAQIHKSLDAEITKTLDSNENKLRILEEKLK
CCCCEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHH
ILNPDELLEKGYVVKDPDEIRKSKAKNVIIVLFLAIVIVLLILLSLK
HCCHHHHHHCCCEECCHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA