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The map label for this gene is murA [H]

Identifier: 148381505

GI number: 148381505

Start: 3811227

End: 3812492

Strand: Direct

Name: murA [H]

Synonym: CBO3566

Alternate gene names: 148381505

Gene position: 3811227-3812492 (Clockwise)

Preceding gene: 148381503

Following gene: 148381506

Centisome position: 98.05

GC content: 34.28

Gene sequence:

>1266_bases
ATGGATGCGGGGATGAGTAAATTAAAAATAACAGGAGGTAACCCCCTCTTTGGAAAAGTTGAAATTAGTGGAGCAAAAAA
TGCAGCAGTAGCTATATTACCAGCTACTATTATGGCTAGCAAAGGAGTTTGTACTATAGAGAATACTCCAAATATTGAAG
ATGTACATTGTATTGAAAGAATTTTAAATGGATTGGGTTGTGAAATTAAAAGACAAAGCAATTCTATTTTACAAATAGAT
AGTACTAATATAACAAAAACAGATGCTAATACTGAAGATGTAAGAAAAATGAGAGCTTCTTATTATCTTATCGGAGCTTT
ATTAGGAAGGTTTAAAAAAGCCAGAGTAGAATTACCTGGTGGATGTCCTATAGGTGTTAGACCTATAGATCAACACATTA
AAGGTTTTGAAGCTTTAGGAGCTCATGTCGAAATAGAACATGGTGCTGTAATTGTCAAAGCAGATAAATTAATAGGAACT
AATATATTTTTTGACGTTGTTAGCGTAGGCGCTACTATAAATGTGATGTTAGCTGCCACACTTGCTGAAGGCAATACTGT
GCTAGAAAATGTAGCAAAGGAACCTCACGTAGTAGATGTAGCTAATTTTTTAAATAGTATGGGAGCTAATATCAAAGGTG
CTGGAACAGACATTATAAGAGTTACTGGTGTTAAAGAATTAAAAGGCTGTACTTATAGTGTAATACCTGATCAAATTGAA
GCTGGTACATATATGATAGCAACAGCTGCCTGCGGTGGAGAAGTTACAATAAATAACGTAATACCTAAACACTTAGAATC
TATAACAGCAAAACTTATAGAAATGGGAGTAGATGTTATAGAAAATGGAGATTCTGTTACAGTAAAATCTAAAGGTAATT
TTAAAGGCGCTAATATAAAAACTCAACCTTACCCAGGATTTCCAACGGATGTGCAACAACCAATGAGCACACTTTTAACT
ATTGCAAAAGGAAGAAGTATTGTAAATGAAAGCATTTGGGAAAGTAGATTTAAACATGTAGATGAATTGAAGAAAATGGG
AGCAAATATTAAGGTAGAAGGTAGAACAGCCATTATAGATGGTGTACCTAAACTTACAGGAGCTATAGTAAAAGCTACGG
ATTTGAGAGCTGGGGCTGCTATGGTAATTGCTGGATTATTAGCTGAAGGTGATACCGAAATTCTTGGTGTGGAGCATATA
GATAGAGGATACCCAAATATTGAAAATAAATTTAGATCTTTAGGGGCTACTATAGTTAGACTATAG

Upstream 100 bases:

>100_bases
AAATTTGGTGTTAAAATAATAAATAGTTATGATATAATATATTTTGTTACATAGGTTTGAAATTAACGATTAGTTTAAAT
ATATAAATTCTAAAGTAAGG

Downstream 100 bases:

>100_bases
TTAAGTTACAATTTAAAATTTTATTATGATTTTTTGTTCTCTTTATAGTGGTAGTAGTGGTAATTCCATATTTATATCCT
CTGAAAAATCAAAAATACTG

Product: UDP-N-acetylglucosamine 1-carboxyvinyltransferase

Products: NA

Alternate protein names: Enoylpyruvate transferase; UDP-N-acetylglucosamine enolpyruvyl transferase; EPT [H]

Number of amino acids: Translated: 421; Mature: 421

Protein sequence:

>421_residues
MDAGMSKLKITGGNPLFGKVEISGAKNAAVAILPATIMASKGVCTIENTPNIEDVHCIERILNGLGCEIKRQSNSILQID
STNITKTDANTEDVRKMRASYYLIGALLGRFKKARVELPGGCPIGVRPIDQHIKGFEALGAHVEIEHGAVIVKADKLIGT
NIFFDVVSVGATINVMLAATLAEGNTVLENVAKEPHVVDVANFLNSMGANIKGAGTDIIRVTGVKELKGCTYSVIPDQIE
AGTYMIATAACGGEVTINNVIPKHLESITAKLIEMGVDVIENGDSVTVKSKGNFKGANIKTQPYPGFPTDVQQPMSTLLT
IAKGRSIVNESIWESRFKHVDELKKMGANIKVEGRTAIIDGVPKLTGAIVKATDLRAGAAMVIAGLLAEGDTEILGVEHI
DRGYPNIENKFRSLGATIVRL

Sequences:

>Translated_421_residues
MDAGMSKLKITGGNPLFGKVEISGAKNAAVAILPATIMASKGVCTIENTPNIEDVHCIERILNGLGCEIKRQSNSILQID
STNITKTDANTEDVRKMRASYYLIGALLGRFKKARVELPGGCPIGVRPIDQHIKGFEALGAHVEIEHGAVIVKADKLIGT
NIFFDVVSVGATINVMLAATLAEGNTVLENVAKEPHVVDVANFLNSMGANIKGAGTDIIRVTGVKELKGCTYSVIPDQIE
AGTYMIATAACGGEVTINNVIPKHLESITAKLIEMGVDVIENGDSVTVKSKGNFKGANIKTQPYPGFPTDVQQPMSTLLT
IAKGRSIVNESIWESRFKHVDELKKMGANIKVEGRTAIIDGVPKLTGAIVKATDLRAGAAMVIAGLLAEGDTEILGVEHI
DRGYPNIENKFRSLGATIVRL
>Mature_421_residues
MDAGMSKLKITGGNPLFGKVEISGAKNAAVAILPATIMASKGVCTIENTPNIEDVHCIERILNGLGCEIKRQSNSILQID
STNITKTDANTEDVRKMRASYYLIGALLGRFKKARVELPGGCPIGVRPIDQHIKGFEALGAHVEIEHGAVIVKADKLIGT
NIFFDVVSVGATINVMLAATLAEGNTVLENVAKEPHVVDVANFLNSMGANIKGAGTDIIRVTGVKELKGCTYSVIPDQIE
AGTYMIATAACGGEVTINNVIPKHLESITAKLIEMGVDVIENGDSVTVKSKGNFKGANIKTQPYPGFPTDVQQPMSTLLT
IAKGRSIVNESIWESRFKHVDELKKMGANIKVEGRTAIIDGVPKLTGAIVKATDLRAGAAMVIAGLLAEGDTEILGVEHI
DRGYPNIENKFRSLGATIVRL

Specific function: Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine [H]

COG id: COG0766

COG function: function code M; UDP-N-acetylglucosamine enolpyruvyl transferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the EPSP synthase family. MurA subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789580, Length=419, Percent_Identity=45.1073985680191, Blast_Score=360, Evalue=1e-100,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001986
- InterPro:   IPR013792
- InterPro:   IPR005750 [H]

Pfam domain/function: PF00275 EPSP_synthase [H]

EC number: =2.5.1.7 [H]

Molecular weight: Translated: 44733; Mature: 44733

Theoretical pI: Translated: 7.53; Mature: 7.53

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDAGMSKLKITGGNPLFGKVEISGAKNAAVAILPATIMASKGVCTIENTPNIEDVHCIER
CCCCCCEEEEECCCCEEEEEEECCCCCCEEEEEEHHHHCCCCEEEECCCCCCHHHHHHHH
ILNGLGCEIKRQSNSILQIDSTNITKTDANTEDVRKMRASYYLIGALLGRFKKARVELPG
HHHHCCCEEEECCCCEEEEECCCCEECCCCHHHHHHHHHHHHHHHHHHHHHHHCEEECCC
GCPIGVRPIDQHIKGFEALGAHVEIEHGAVIVKADKLIGTNIFFDVVSVGATINVMLAAT
CCCCCCCHHHHHHHHHHHCCCEEEEECCEEEEEECCHHCCHHHHHHHHHCCEEEEEEEEE
LAEGNTVLENVAKEPHVVDVANFLNSMGANIKGAGTDIIRVTGVKELKGCTYSVIPDQIE
ECCCCHHHHHHCCCCCEEHHHHHHHHHCCCCCCCCCCEEEEECCHHHCCCEEEECCCCCC
AGTYMIATAACGGEVTINNVIPKHLESITAKLIEMGVDVIENGDSVTVKSKGNFKGANIK
CCEEEEEEECCCCCEEECCCCHHHHHHHHHHHHHHCHHHEECCCEEEEEECCCCCCCCEE
TQPYPGFPTDVQQPMSTLLTIAKGRSIVNESIWESRFKHVDELKKMGANIKVEGRTAIID
CCCCCCCCHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCEEEEC
GVPKLTGAIVKATDLRAGAAMVIAGLLAEGDTEILGVEHIDRGYPNIENKFRSLGATIVR
CCHHHHHHEEEECCCCCCHHHHHHHHHCCCCCEEEEHHHHCCCCCCHHHHHHHHCHHEEC
L
C
>Mature Secondary Structure
MDAGMSKLKITGGNPLFGKVEISGAKNAAVAILPATIMASKGVCTIENTPNIEDVHCIER
CCCCCCEEEEECCCCEEEEEEECCCCCCEEEEEEHHHHCCCCEEEECCCCCCHHHHHHHH
ILNGLGCEIKRQSNSILQIDSTNITKTDANTEDVRKMRASYYLIGALLGRFKKARVELPG
HHHHCCCEEEECCCCEEEEECCCCEECCCCHHHHHHHHHHHHHHHHHHHHHHHCEEECCC
GCPIGVRPIDQHIKGFEALGAHVEIEHGAVIVKADKLIGTNIFFDVVSVGATINVMLAAT
CCCCCCCHHHHHHHHHHHCCCEEEEECCEEEEEECCHHCCHHHHHHHHHCCEEEEEEEEE
LAEGNTVLENVAKEPHVVDVANFLNSMGANIKGAGTDIIRVTGVKELKGCTYSVIPDQIE
ECCCCHHHHHHCCCCCEEHHHHHHHHHCCCCCCCCCCEEEEECCHHHCCCEEEECCCCCC
AGTYMIATAACGGEVTINNVIPKHLESITAKLIEMGVDVIENGDSVTVKSKGNFKGANIK
CCEEEEEEECCCCCEEECCCCHHHHHHHHHHHHHHCHHHEECCCEEEEEECCCCCCCCEE
TQPYPGFPTDVQQPMSTLLTIAKGRSIVNESIWESRFKHVDELKKMGANIKVEGRTAIID
CCCCCCCCHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCEEEEC
GVPKLTGAIVKATDLRAGAAMVIAGLLAEGDTEILGVEHIDRGYPNIENKFRSLGATIVR
CCHHHHHHEEEECCCCCCHHHHHHHHHCCCCCEEEEHHHHCCCCCCHHHHHHHHCHHEEC
L
C

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA