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The map label for this gene is tkt [C]

Identifier: 148381335

GI number: 148381335

Start: 3635914

End: 3636738

Strand: Reverse

Name: tkt [C]

Synonym: CBO3395

Alternate gene names: 148381335

Gene position: 3636738-3635914 (Counterclockwise)

Preceding gene: 148381336

Following gene: 148381334

Centisome position: 93.56

GC content: 33.82

Gene sequence:

>825_bases
ATGAAGAAGAACATAGAAGAGCTACAAGATATAGCTAAAGTTATTAGAAAAGATATAGTTTCAATGTTAACTGAATCTGC
TTCTGGACATCCAGGAGGTTCTTTATCAGCAGTAGAGATATTGACTGCTTTATATTTTAATGAGATGAATATAGACCCTA
CTAATACTAGGGATTTAAATAGGGACAGATTTGTTCTTTCTAAAGGGCATGCTGCTCCAGTATTATATAGTACTTTAGCA
AGAAGAGGATTTTTTAATCCAGAAGAGCTAAAGACTTTAAGAAAAATTGGATCAATATTACAAGGTCATCCAAATATGAA
TGACGTTCCAGGTATAGATATGTCAACAGGCTCTTTAGGTCAAGGAATATCAACAGCAGTAGGTATGGCTGTAGCCGGAA
AACTTGATGAAAAAGATTACAGAGTATATACACTACTTGGAGATGGAGAATTAGAGGAAGGACAAGTTTGGGAAGCAGCT
ATGGCAGCAGCTCATTACAAATTAGATAATTTGACTGCCTTTGTAGATTACAATGGATTACAAATAGATGGACCTTGTAG
TGAAGTTATGTCAGCGGAACCTATAGCGGATAAATTTAGAGCTTTTAATTGGAATGTTATAGAAATAGATGGACATGATT
TCAATTCTATATTAAATGCTATAGAAAGTTCAAAAAATATTAAAGAAAGACCAACTATGATAGTATGTAAAACTATAAAA
GGTAAGGGTGTTTCTTTTATGGAAAATGAAGCTGGATGGCATGGTAAAGCACCAAGTGCAGAAGAATGTGAAAAAGCTAT
ATGTGAAATCGGAGGTGACAAATAA

Upstream 100 bases:

>100_bases
GTTTTAATATATAGCTTTTGCACCTATATATTAAAATTAATTTTTATGTTACAATAATATAGTAAATAAGGGTAATTAAA
AAATACTTGGAGGTAAAAAT

Downstream 100 bases:

>100_bases
TGGGAGTTAAAATAGCTACAAGAGAAGCATACGGAAAAACATTAGCTAAATTAGCAGAAGAAAATTCAAAGATAGTGGTT
TTAGATGCAGACCTTTCAAA

Product: putative transketolase, N-terminal subunit

Products: NA

Alternate protein names: TK [H]

Number of amino acids: Translated: 274; Mature: 274

Protein sequence:

>274_residues
MKKNIEELQDIAKVIRKDIVSMLTESASGHPGGSLSAVEILTALYFNEMNIDPTNTRDLNRDRFVLSKGHAAPVLYSTLA
RRGFFNPEELKTLRKIGSILQGHPNMNDVPGIDMSTGSLGQGISTAVGMAVAGKLDEKDYRVYTLLGDGELEEGQVWEAA
MAAAHYKLDNLTAFVDYNGLQIDGPCSEVMSAEPIADKFRAFNWNVIEIDGHDFNSILNAIESSKNIKERPTMIVCKTIK
GKGVSFMENEAGWHGKAPSAEECEKAICEIGGDK

Sequences:

>Translated_274_residues
MKKNIEELQDIAKVIRKDIVSMLTESASGHPGGSLSAVEILTALYFNEMNIDPTNTRDLNRDRFVLSKGHAAPVLYSTLA
RRGFFNPEELKTLRKIGSILQGHPNMNDVPGIDMSTGSLGQGISTAVGMAVAGKLDEKDYRVYTLLGDGELEEGQVWEAA
MAAAHYKLDNLTAFVDYNGLQIDGPCSEVMSAEPIADKFRAFNWNVIEIDGHDFNSILNAIESSKNIKERPTMIVCKTIK
GKGVSFMENEAGWHGKAPSAEECEKAICEIGGDK
>Mature_274_residues
MKKNIEELQDIAKVIRKDIVSMLTESASGHPGGSLSAVEILTALYFNEMNIDPTNTRDLNRDRFVLSKGHAAPVLYSTLA
RRGFFNPEELKTLRKIGSILQGHPNMNDVPGIDMSTGSLGQGISTAVGMAVAGKLDEKDYRVYTLLGDGELEEGQVWEAA
MAAAHYKLDNLTAFVDYNGLQIDGPCSEVMSAEPIADKFRAFNWNVIEIDGHDFNSILNAIESSKNIKERPTMIVCKTIK
GKGVSFMENEAGWHGKAPSAEECEKAICEIGGDK

Specific function: Unknown

COG id: COG3959

COG function: function code G; Transketolase, N-terminal subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the transketolase family [H]

Homologues:

Organism=Homo sapiens, GI205277463, Length=273, Percent_Identity=42.8571428571429, Blast_Score=214, Evalue=7e-56,
Organism=Homo sapiens, GI4507521, Length=273, Percent_Identity=42.8571428571429, Blast_Score=214, Evalue=7e-56,
Organism=Homo sapiens, GI133778974, Length=269, Percent_Identity=40.8921933085502, Blast_Score=207, Evalue=7e-54,
Organism=Homo sapiens, GI225637459, Length=270, Percent_Identity=31.4814814814815, Blast_Score=139, Evalue=2e-33,
Organism=Homo sapiens, GI225637461, Length=233, Percent_Identity=32.1888412017167, Blast_Score=122, Evalue=3e-28,
Organism=Homo sapiens, GI225637463, Length=160, Percent_Identity=38.75, Blast_Score=119, Evalue=2e-27,
Organism=Escherichia coli, GI1788808, Length=275, Percent_Identity=35.2727272727273, Blast_Score=169, Evalue=2e-43,
Organism=Escherichia coli, GI48994911, Length=258, Percent_Identity=37.984496124031, Blast_Score=164, Evalue=8e-42,
Organism=Caenorhabditis elegans, GI17539652, Length=262, Percent_Identity=45.8015267175573, Blast_Score=224, Evalue=4e-59,
Organism=Saccharomyces cerevisiae, GI6325331, Length=284, Percent_Identity=36.6197183098592, Blast_Score=157, Evalue=2e-39,
Organism=Saccharomyces cerevisiae, GI6319593, Length=286, Percent_Identity=34.6153846153846, Blast_Score=153, Evalue=3e-38,
Organism=Drosophila melanogaster, GI45551847, Length=255, Percent_Identity=40.7843137254902, Blast_Score=206, Evalue=1e-53,
Organism=Drosophila melanogaster, GI45550715, Length=255, Percent_Identity=40.7843137254902, Blast_Score=206, Evalue=1e-53,
Organism=Drosophila melanogaster, GI24666278, Length=267, Percent_Identity=40.8239700374532, Blast_Score=201, Evalue=5e-52,
Organism=Drosophila melanogaster, GI24645119, Length=217, Percent_Identity=41.9354838709677, Blast_Score=181, Evalue=5e-46,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005474 [H]

Pfam domain/function: PF00456 Transketolase_N [H]

EC number: =2.2.1.1 [H]

Molecular weight: Translated: 29941; Mature: 29941

Theoretical pI: Translated: 4.86; Mature: 4.86

Prosite motif: PS00801 TRANSKETOLASE_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKNIEELQDIAKVIRKDIVSMLTESASGHPGGSLSAVEILTALYFNEMNIDPTNTRDLN
CCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCC
RDRFVLSKGHAAPVLYSTLARRGFFNPEELKTLRKIGSILQGHPNMNDVPGIDMSTGSLG
CCEEEEECCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCC
QGISTAVGMAVAGKLDEKDYRVYTLLGDGELEEGQVWEAAMAAAHYKLDNLTAFVDYNGL
CCHHHHHHHHHHCCCCCCCEEEEEEECCCCCCCCHHHHHHHHHHHHHHCCEEEEEECCCE
QIDGPCSEVMSAEPIADKFRAFNWNVIEIDGHDFNSILNAIESSKNIKERPTMIVCKTIK
EECCCHHHHHCCCHHHHHHHHCCCEEEEECCCCHHHHHHHHHHCCCHHHCCCEEEEEECC
GKGVSFMENEAGWHGKAPSAEECEKAICEIGGDK
CCCCEEECCCCCCCCCCCCHHHHHHHHHHCCCCC
>Mature Secondary Structure
MKKNIEELQDIAKVIRKDIVSMLTESASGHPGGSLSAVEILTALYFNEMNIDPTNTRDLN
CCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCC
RDRFVLSKGHAAPVLYSTLARRGFFNPEELKTLRKIGSILQGHPNMNDVPGIDMSTGSLG
CCEEEEECCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCC
QGISTAVGMAVAGKLDEKDYRVYTLLGDGELEEGQVWEAAMAAAHYKLDNLTAFVDYNGL
CCHHHHHHHHHHCCCCCCCEEEEEEECCCCCCCCHHHHHHHHHHHHHHCCEEEEEECCCE
QIDGPCSEVMSAEPIADKFRAFNWNVIEIDGHDFNSILNAIESSKNIKERPTMIVCKTIK
EECCCHHHHHCCCHHHHHHHHCCCEEEEECCCCHHHHHHHHHHCCCHHHCCCEEEEEECC
GKGVSFMENEAGWHGKAPSAEECEKAICEIGGDK
CCCCEEECCCCCCCCCCCCHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]