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The map label for this gene is pyrF

Identifier: 148381187

GI number: 148381187

Start: 3448031

End: 3448882

Strand: Reverse

Name: pyrF

Synonym: CBO3238

Alternate gene names: 148381187

Gene position: 3448882-3448031 (Counterclockwise)

Preceding gene: 148381188

Following gene: 148381186

Centisome position: 88.73

GC content: 28.76

Gene sequence:

>852_bases
TTGATTATAGATAAATTGTATGAAAACGTAGAGAAAAAAGGATGTGTTTGTGTAGGCCTTGATACGGATATAAGTTATCT
ACCAAAAGGATTTTTAAATAAATTTACTAACATAGAAGATGCTATATTTGCATTTAATCAAAGGATAGTTGATTCAACTT
TTGATGTATCAGCTTGTTACAAAGTTCAGATAGCTTATTATGAGGCTATGGGAATTAAAGGAATGATTTTATATAAGAAA
ACTTTAGAATATATAAGAAAAAAAGGCGGTATAGTTATAGCAGATATAAAAAGAGGAGATATATCTGCTACAGCTAAAAT
GTATGCAAAAGCTCATTTTGAAGGAGATTTTGAAAGTGATTTTATAACATTAAACCCATATATGGGAATGGATACTTTAG
AACCTTATAAAGATTATTTCAAAAATAAGGAGAAGGGAGTTTTCTTGTTATTAAGAACTTCTAATGAAGGTTCAAAGGAT
ATACAATATTTAGATTTGAAAGACAATAAAAAGGTATACAACAAAGTAGGAGAAAAAATAGAGAACATAGGGAAAGAATT
TTTAGGCAATTGTGGATATAGTTCTATAGGAGCAGTAGTTGGATGTACAGCAGAAGAAAATAATATTAGAAAAGAATTAA
AACATACATTTTTCTTAATACCTGGCTATGGCGCTCAGGGAGGGAAAGCTGAAGTTGCTAAATCTTATTTAAGTGGAGGT
AACGGAGGTATTGTAAATTCTTCAAGAGGGATATTGCTTGCATATAAAAAATATGATGAAGAAGGAAAAAACTTTGAAGA
ATGTGCAAGAAATGAAGTTATAAATATGAAAAAAACTTTACAGATTATATAG

Upstream 100 bases:

>100_bases
CTATGGATGGTATGTATCTTAAAGGAAGAATTAAAGTTACATTTAAAGCAGGATGTATAGTATATAGTGAATTTTAATAG
AAAAAGAAAGGATGAATAAA

Downstream 100 bases:

>100_bases
ATTTACATTAAGTTATTATGAGTATTGGAAGAGCTTATTAAGGAGTGTATTAGTAGTTGCTTCTTATCTAAAAAGAATAG
GGTATTGGACTTAGTAGCTA

Product: orotidine 5'-phosphate decarboxylase

Products: NA

Alternate protein names: OMP decarboxylase; OMPDCase; OMPdecase

Number of amino acids: Translated: 283; Mature: 283

Protein sequence:

>283_residues
MIIDKLYENVEKKGCVCVGLDTDISYLPKGFLNKFTNIEDAIFAFNQRIVDSTFDVSACYKVQIAYYEAMGIKGMILYKK
TLEYIRKKGGIVIADIKRGDISATAKMYAKAHFEGDFESDFITLNPYMGMDTLEPYKDYFKNKEKGVFLLLRTSNEGSKD
IQYLDLKDNKKVYNKVGEKIENIGKEFLGNCGYSSIGAVVGCTAEENNIRKELKHTFFLIPGYGAQGGKAEVAKSYLSGG
NGGIVNSSRGILLAYKKYDEEGKNFEECARNEVINMKKTLQII

Sequences:

>Translated_283_residues
MIIDKLYENVEKKGCVCVGLDTDISYLPKGFLNKFTNIEDAIFAFNQRIVDSTFDVSACYKVQIAYYEAMGIKGMILYKK
TLEYIRKKGGIVIADIKRGDISATAKMYAKAHFEGDFESDFITLNPYMGMDTLEPYKDYFKNKEKGVFLLLRTSNEGSKD
IQYLDLKDNKKVYNKVGEKIENIGKEFLGNCGYSSIGAVVGCTAEENNIRKELKHTFFLIPGYGAQGGKAEVAKSYLSGG
NGGIVNSSRGILLAYKKYDEEGKNFEECARNEVINMKKTLQII
>Mature_283_residues
MIIDKLYENVEKKGCVCVGLDTDISYLPKGFLNKFTNIEDAIFAFNQRIVDSTFDVSACYKVQIAYYEAMGIKGMILYKK
TLEYIRKKGGIVIADIKRGDISATAKMYAKAHFEGDFESDFITLNPYMGMDTLEPYKDYFKNKEKGVFLLLRTSNEGSKD
IQYLDLKDNKKVYNKVGEKIENIGKEFLGNCGYSSIGAVVGCTAEENNIRKELKHTFFLIPGYGAQGGKAEVAKSYLSGG
NGGIVNSSRGILLAYKKYDEEGKNFEECARNEVINMKKTLQII

Specific function: Unknown

COG id: COG0284

COG function: function code F; Orotidine-5'-phosphate decarboxylase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the OMP decarboxylase family. Type 2 subfamily

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): PYRF_CLOB1 (A7FYI9)

Other databases:

- EMBL:   CP000726
- RefSeq:   YP_001385562.1
- ProteinModelPortal:   A7FYI9
- SMR:   A7FYI9
- STRING:   A7FYI9
- GeneID:   5394542
- GenomeReviews:   CP000726_GR
- KEGG:   cba:CLB_3275
- eggNOG:   COG0284
- HOGENOM:   HBG348634
- OMA:   LLCRTSN
- ProtClustDB:   PRK00125
- BioCyc:   CBOT441770:CLB_3275-MONOMER
- HAMAP:   MF_01215
- InterPro:   IPR013785
- InterPro:   IPR011995
- InterPro:   IPR001754
- InterPro:   IPR011060
- Gene3D:   G3DSA:3.20.20.70
- SMART:   SM00934
- TIGRFAMs:   TIGR02127

Pfam domain/function: PF00215 OMPdecase; SSF51366 RibP_bind_barrel

EC number: =4.1.1.23

Molecular weight: Translated: 31786; Mature: 31786

Theoretical pI: Translated: 8.30; Mature: 8.30

Prosite motif: PS00156 OMPDECASE

Important sites: ACT_SITE 97-97

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIIDKLYENVEKKGCVCVGLDTDISYLPKGFLNKFTNIEDAIFAFNQRIVDSTFDVSACY
CCHHHHHHHHHHCCCEEEEECCCHHHCCHHHHHHHCCHHHHHHHHHHHHHCCCCCCEEEE
KVQIAYYEAMGIKGMILYKKTLEYIRKKGGIVIADIKRGDISATAKMYAKAHFEGDFESD
EEEEEEEECCCCCEEEEHHHHHHHHHHCCCEEEEEECCCCCHHHHHHHHHHHCCCCCCCC
FITLNPYMGMDTLEPYKDYFKNKEKGVFLLLRTSNEGSKDIQYLDLKDNKKVYNKVGEKI
EEEECCCCCCCCCHHHHHHHCCCCCCEEEEEEECCCCCCCEEEEECCCCHHHHHHHHHHH
ENIGKEFLGNCGYSSIGAVVGCTAEENNIRKELKHTFFLIPGYGAQGGKAEVAKSYLSGG
HHHHHHHHCCCCCCHHHHEEECCCCHHHHHHHHHHEEEEEECCCCCCCHHHHHHHHHCCC
NGGIVNSSRGILLAYKKYDEEGKNFEECARNEVINMKKTLQII
CCCEEECCCCEEEEEECCCCCCCCHHHHHHHHHHCHHHHEECC
>Mature Secondary Structure
MIIDKLYENVEKKGCVCVGLDTDISYLPKGFLNKFTNIEDAIFAFNQRIVDSTFDVSACY
CCHHHHHHHHHHCCCEEEEECCCHHHCCHHHHHHHCCHHHHHHHHHHHHHCCCCCCEEEE
KVQIAYYEAMGIKGMILYKKTLEYIRKKGGIVIADIKRGDISATAKMYAKAHFEGDFESD
EEEEEEEECCCCCEEEEHHHHHHHHHHCCCEEEEEECCCCCHHHHHHHHHHHCCCCCCCC
FITLNPYMGMDTLEPYKDYFKNKEKGVFLLLRTSNEGSKDIQYLDLKDNKKVYNKVGEKI
EEEECCCCCCCCCHHHHHHHCCCCCCEEEEEEECCCCCCCEEEEECCCCHHHHHHHHHHH
ENIGKEFLGNCGYSSIGAVVGCTAEENNIRKELKHTFFLIPGYGAQGGKAEVAKSYLSGG
HHHHHHHHCCCCCCHHHHEEECCCCHHHHHHHHHHEEEEEECCCCCCCHHHHHHHHHCCC
NGGIVNSSRGILLAYKKYDEEGKNFEECARNEVINMKKTLQII
CCCEEECCCCEEEEEECCCCCCCCHHHHHHHHHHCHHHHEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA