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The map label for this gene is etfA [H]

Identifier: 148381145

GI number: 148381145

Start: 3405772

End: 3406776

Strand: Reverse

Name: etfA [H]

Synonym: CBO3197

Alternate gene names: 148381145

Gene position: 3406776-3405772 (Counterclockwise)

Preceding gene: 148381146

Following gene: 148381144

Centisome position: 87.65

GC content: 29.65

Gene sequence:

>1005_bases
ATGAATTTATCAGATTTTAAAGGTGTTTGGATTTTTGCAGAACAGAGAGAAGGTAAGCTTCAAAAAGTAGCTTTAGAGCT
AATAGGTAAAGGTAAAGAGTTATCTAAAAAATTAGGAGTAGAATTAACTGCTGTTTTATTAGGATATAATATTGATGATA
TACCAAGACAATTAATAGAGTATGGTGCAGATAAAGTATTATATGTGAATAATCCATTATTAAAAAATTATACTACAGAT
GGATATACAAAAGTTATAAATGATTTAATAGAAGAAAGAAAACCTGAAATATTATTAGTTGGAGCTACTTATATAGGAAG
AGATTTAGCACCAAGAATTTCATCTAGATTAGGTACAGGACTTACAGCAGATTGTACAGGATTAGATATAGATGATGATA
CAAGAAATCTTTTAATGACAAGACCTGCTTTTGGTGGTAATTTAATGGCTACAATAATTTGTGACAGCAATAGACCTCAA
ATGTCTACAGTAAGGCCAGGCGTTTTTCAAAAGTTAGAAAAAGATGCTAATAGAGATGGAAGTATTGAAAATATAAAAGT
AAATTTAAAAGAATCAGATATAAAAATAAAAATAAAAGAAATTGTTAAATTAGCAAAAGAAATAGAAGATATAAGTGAAG
CAAAAATATTGGTTTCAGGTGGAAGAGGACTTGGAAGCCCAGAAGGATTTAAATTATTAAGAGAATTGGCTGATTTAATG
GGAGGAGCTATATCAGGTTCTCGTGCGGTTGTAGATAGTGGATGGATAGATAAAGCTTATCAGGTTGGACAAACAGGAAA
AACAGTTAGACCTAATTTATATATAGCTTGTGGAATATCAGGAGCTATTCAGCATCTAGCAGGAATGCAAGACAGTGACT
ATATTATAGCTATAAATAAAGATGAATCAGCACCAATAATGCAAGTAGCAGATTTATCTATAGTAGGAGATTACAAAAAA
ATATTACCTTCTATGATAGATGAAATAAAAAAGATTAATAATTAG

Upstream 100 bases:

>100_bases
AAGAGAAGGAGTTTTGGTAAATAAGCCTTTTAAAGAAGCGGCACAGTATGCAGCAGAAAAATTAAAAGAAAAACATTTTA
TTTAGGTTGGGGGAGATATG

Downstream 100 bases:

>100_bases
ATAAAATAGTAATAGTTACTTTAAAATTTGATTATAAAATATATTGTAATCATATAAAAAAAGAATGTGAAATATAAATA
ATATATCACATTCTTTTTTT

Product: electron transfer flavoprotein, alpha subunit/FixB family protein

Products: NA

Alternate protein names: Alpha-ETF; Electron transfer flavoprotein large subunit; ETFLS [H]

Number of amino acids: Translated: 334; Mature: 334

Protein sequence:

>334_residues
MNLSDFKGVWIFAEQREGKLQKVALELIGKGKELSKKLGVELTAVLLGYNIDDIPRQLIEYGADKVLYVNNPLLKNYTTD
GYTKVINDLIEERKPEILLVGATYIGRDLAPRISSRLGTGLTADCTGLDIDDDTRNLLMTRPAFGGNLMATIICDSNRPQ
MSTVRPGVFQKLEKDANRDGSIENIKVNLKESDIKIKIKEIVKLAKEIEDISEAKILVSGGRGLGSPEGFKLLRELADLM
GGAISGSRAVVDSGWIDKAYQVGQTGKTVRPNLYIACGISGAIQHLAGMQDSDYIIAINKDESAPIMQVADLSIVGDYKK
ILPSMIDEIKKINN

Sequences:

>Translated_334_residues
MNLSDFKGVWIFAEQREGKLQKVALELIGKGKELSKKLGVELTAVLLGYNIDDIPRQLIEYGADKVLYVNNPLLKNYTTD
GYTKVINDLIEERKPEILLVGATYIGRDLAPRISSRLGTGLTADCTGLDIDDDTRNLLMTRPAFGGNLMATIICDSNRPQ
MSTVRPGVFQKLEKDANRDGSIENIKVNLKESDIKIKIKEIVKLAKEIEDISEAKILVSGGRGLGSPEGFKLLRELADLM
GGAISGSRAVVDSGWIDKAYQVGQTGKTVRPNLYIACGISGAIQHLAGMQDSDYIIAINKDESAPIMQVADLSIVGDYKK
ILPSMIDEIKKINN
>Mature_334_residues
MNLSDFKGVWIFAEQREGKLQKVALELIGKGKELSKKLGVELTAVLLGYNIDDIPRQLIEYGADKVLYVNNPLLKNYTTD
GYTKVINDLIEERKPEILLVGATYIGRDLAPRISSRLGTGLTADCTGLDIDDDTRNLLMTRPAFGGNLMATIICDSNRPQ
MSTVRPGVFQKLEKDANRDGSIENIKVNLKESDIKIKIKEIVKLAKEIEDISEAKILVSGGRGLGSPEGFKLLRELADLM
GGAISGSRAVVDSGWIDKAYQVGQTGKTVRPNLYIACGISGAIQHLAGMQDSDYIIAINKDESAPIMQVADLSIVGDYKK
ILPSMIDEIKKINN

Specific function: The electron transfer flavoprotein serves as a specific electron acceptor for other dehydrogenases. It transfers the electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase) [H]

COG id: COG2025

COG function: function code C; Electron transfer flavoprotein, alpha subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ETF alpha-subunit/fixB family [H]

Homologues:

Organism=Homo sapiens, GI4503607, Length=334, Percent_Identity=36.2275449101796, Blast_Score=181, Evalue=8e-46,
Organism=Homo sapiens, GI189181759, Length=273, Percent_Identity=39.5604395604396, Blast_Score=168, Evalue=5e-42,
Organism=Escherichia coli, GI1787990, Length=334, Percent_Identity=29.6407185628743, Blast_Score=139, Evalue=3e-34,
Organism=Escherichia coli, GI1786226, Length=334, Percent_Identity=29.3413173652695, Blast_Score=122, Evalue=3e-29,
Organism=Escherichia coli, GI87082157, Length=253, Percent_Identity=25.6916996047431, Blast_Score=73, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI17506929, Length=329, Percent_Identity=36.1702127659575, Blast_Score=178, Evalue=4e-45,
Organism=Saccharomyces cerevisiae, GI6325261, Length=235, Percent_Identity=35.7446808510638, Blast_Score=152, Evalue=7e-38,
Organism=Drosophila melanogaster, GI17136898, Length=321, Percent_Identity=34.5794392523364, Blast_Score=167, Evalue=7e-42,
Organism=Drosophila melanogaster, GI24652801, Length=321, Percent_Identity=34.5794392523364, Blast_Score=167, Evalue=7e-42,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001308
- InterPro:   IPR014730
- InterPro:   IPR014731
- InterPro:   IPR018206
- InterPro:   IPR014729 [H]

Pfam domain/function: PF01012 ETF; PF00766 ETF_alpha [H]

EC number: NA

Molecular weight: Translated: 36555; Mature: 36555

Theoretical pI: Translated: 5.60; Mature: 5.60

Prosite motif: PS00696 ETF_ALPHA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNLSDFKGVWIFAEQREGKLQKVALELIGKGKELSKKLGVELTAVLLGYNIDDIPRQLIE
CCCCCCCCEEEEEECCCCHHHHHHHHHHCCCHHHHHHHCCEEEEHHHCCCCCHHHHHHHH
YGADKVLYVNNPLLKNYTTDGYTKVINDLIEERKPEILLVGATYIGRDLAPRISSRLGTG
HCCCEEEEECCCHHCCCCCCHHHHHHHHHHHHCCCCEEEEECHHHCCHHHHHHHHHHCCC
LTADCTGLDIDDDTRNLLMTRPAFGGNLMATIICDSNRPQMSTVRPGVFQKLEKDANRDG
CCCCCCCCCCCCCCCCEEEECCCCCCCEEEEEEECCCCCCCCCCCCHHHHHHHHHCCCCC
SIENIKVNLKESDIKIKIKEIVKLAKEIEDISEAKILVSGGRGLGSPEGFKLLRELADLM
CEEEEEEEEECCCEEEEHHHHHHHHHHHHHHHHCEEEEECCCCCCCHHHHHHHHHHHHHH
GGAISGSRAVVDSGWIDKAYQVGQTGKTVRPNLYIACGISGAIQHLAGMQDSDYIIAINK
CCCCCCCCEEEECCCCHHHHHCCCCCCEECCCEEEEECCHHHHHHHHCCCCCCEEEEECC
DESAPIMQVADLSIVGDYKKILPSMIDEIKKINN
CCCCCEEEEECHHEECHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MNLSDFKGVWIFAEQREGKLQKVALELIGKGKELSKKLGVELTAVLLGYNIDDIPRQLIE
CCCCCCCCEEEEEECCCCHHHHHHHHHHCCCHHHHHHHCCEEEEHHHCCCCCHHHHHHHH
YGADKVLYVNNPLLKNYTTDGYTKVINDLIEERKPEILLVGATYIGRDLAPRISSRLGTG
HCCCEEEEECCCHHCCCCCCHHHHHHHHHHHHCCCCEEEEECHHHCCHHHHHHHHHHCCC
LTADCTGLDIDDDTRNLLMTRPAFGGNLMATIICDSNRPQMSTVRPGVFQKLEKDANRDG
CCCCCCCCCCCCCCCCEEEECCCCCCCEEEEEEECCCCCCCCCCCCHHHHHHHHHCCCCC
SIENIKVNLKESDIKIKIKEIVKLAKEIEDISEAKILVSGGRGLGSPEGFKLLRELADLM
CEEEEEEEEECCCEEEEHHHHHHHHHHHHHHHHCEEEEECCCCCCCHHHHHHHHHHHHHH
GGAISGSRAVVDSGWIDKAYQVGQTGKTVRPNLYIACGISGAIQHLAGMQDSDYIIAINK
CCCCCCCCEEEECCCCHHHHHCCCCCCEECCCEEEEECCHHHHHHHHCCCCCCEEEEECC
DESAPIMQVADLSIVGDYKKILPSMIDEIKKINN
CCCCCEEEEECHHEECHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8655474; 11466286 [H]