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The map label for this gene is mrdB [H]

Identifier: 148380946

GI number: 148380946

Start: 3189160

End: 3190278

Strand: Reverse

Name: mrdB [H]

Synonym: CBO2995

Alternate gene names: 148380946

Gene position: 3190278-3189160 (Counterclockwise)

Preceding gene: 148380947

Following gene: 148380945

Centisome position: 82.08

GC content: 28.24

Gene sequence:

>1119_bases
ATGTTTGATAAATTTTTTATAAATAGAAAACTTTTAAAAGAGTTAGATTATAGTATGATTATAATTTCTGTAGCAATAAT
GATTTTTAGTGCTTTAAATATATATAGTGCTACCCATATGAAATATGGTACAAGCTTTTTCCAAAAACAATTAATTTGGT
TAGCTGTAGGCCTTATTATAATTTATGTAGTTCTAATATTTGATTATATTATTATTGAAAATTATGCCAATATATTTTAT
TGGTTTACTATATTTTTGCTTATTTTAAATGATACAGTTCTTAAAAAAACAGTTAATGGTGCAGGCTCTTGGCTGAAGTT
AGGACCTATATCCATACAACCTTCAGAGTTTGCTAAGATGGCTTTAATTATAATGTTAGCTAAGAAATTAGATGATATGG
AAGGAGAAATAAACAACTTAAGGAATTTTTTTACCTTAGCTTTTTATGCTGTAATACCTATGATATTAATTGTAATTCAA
CCGGATATGGGTATGACTATGGTGTTTTTTTTCACTGTGTTAGGTATGTTTTTTGTAGCAGGATTAGACGGAAAAGTAAT
ATCAGGAGGGCTTGCTGGGCTAACTGCACTAGTAGCTATTATTTGGAATTCTCCTTTAATGCAACAATATTGGAAAAATA
GGCTTACTTCATTTTTACATCCTGAAGCAGATGAACTAAATACAGGACTTCAACTTGTGCAATCGAAAATAGGTATAGGG
TCTGGTGGTTTTTTAGGAAAGGGATTTTTAAAAGGAACACAAATAGCAGGTGGATATATTCCAGAAGCTCATACAGATTT
TATTTTTTCTGTTATAGGTGAAGAATGGGGTTTTATAGGAGCTGCAATTTTGTTAATATTTTATGGGATTTTAATATATA
AATTTATAAAAACTGCAAAAAATTCTAAAGATATATTTGGAACTATGGTAACCATTGGTGTAACAGCTTCTTTTATGTTT
TCAATACTTCAAAATATTGGGATGACTATAGGCATAGTACCTATAACAGGTATAGCACTTCCATTTATGAGTTATGGAGG
AAGTTCGTCATTAAATAATTTTTTAGCTTTGGCATTAGTATTAAATATAAATATGAGAAGAAAAAAAATAAATTTTTAA

Upstream 100 bases:

>100_bases
AAATAAAAAATTAAGAGATTTTTTTAGCTATGTATAAATTTGTACATAGCTTTTTGTGTGTGATATGGTATAATCATATT
TGTAATTAAGGGGTGATAAG

Downstream 100 bases:

>100_bases
AAGTATATAAACCTATTTAGTCAAATAAAAATTAGTACTAAATAGGTTTTTTCTTTATAATGAGCTTTTAAAATATATTT
ATGTATACACTATAATATTT

Product: rod shape-determining protein RodA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 372; Mature: 372

Protein sequence:

>372_residues
MFDKFFINRKLLKELDYSMIIISVAIMIFSALNIYSATHMKYGTSFFQKQLIWLAVGLIIIYVVLIFDYIIIENYANIFY
WFTIFLLILNDTVLKKTVNGAGSWLKLGPISIQPSEFAKMALIIMLAKKLDDMEGEINNLRNFFTLAFYAVIPMILIVIQ
PDMGMTMVFFFTVLGMFFVAGLDGKVISGGLAGLTALVAIIWNSPLMQQYWKNRLTSFLHPEADELNTGLQLVQSKIGIG
SGGFLGKGFLKGTQIAGGYIPEAHTDFIFSVIGEEWGFIGAAILLIFYGILIYKFIKTAKNSKDIFGTMVTIGVTASFMF
SILQNIGMTIGIVPITGIALPFMSYGGSSSLNNFLALALVLNINMRRKKINF

Sequences:

>Translated_372_residues
MFDKFFINRKLLKELDYSMIIISVAIMIFSALNIYSATHMKYGTSFFQKQLIWLAVGLIIIYVVLIFDYIIIENYANIFY
WFTIFLLILNDTVLKKTVNGAGSWLKLGPISIQPSEFAKMALIIMLAKKLDDMEGEINNLRNFFTLAFYAVIPMILIVIQ
PDMGMTMVFFFTVLGMFFVAGLDGKVISGGLAGLTALVAIIWNSPLMQQYWKNRLTSFLHPEADELNTGLQLVQSKIGIG
SGGFLGKGFLKGTQIAGGYIPEAHTDFIFSVIGEEWGFIGAAILLIFYGILIYKFIKTAKNSKDIFGTMVTIGVTASFMF
SILQNIGMTIGIVPITGIALPFMSYGGSSSLNNFLALALVLNINMRRKKINF
>Mature_372_residues
MFDKFFINRKLLKELDYSMIIISVAIMIFSALNIYSATHMKYGTSFFQKQLIWLAVGLIIIYVVLIFDYIIIENYANIFY
WFTIFLLILNDTVLKKTVNGAGSWLKLGPISIQPSEFAKMALIIMLAKKLDDMEGEINNLRNFFTLAFYAVIPMILIVIQ
PDMGMTMVFFFTVLGMFFVAGLDGKVISGGLAGLTALVAIIWNSPLMQQYWKNRLTSFLHPEADELNTGLQLVQSKIGIG
SGGFLGKGFLKGTQIAGGYIPEAHTDFIFSVIGEEWGFIGAAILLIFYGILIYKFIKTAKNSKDIFGTMVTIGVTASFMF
SILQNIGMTIGIVPITGIALPFMSYGGSSSLNNFLALALVLNINMRRKKINF

Specific function: This is one of the proteins responsible for the rod shape of the cell. It is required for the expression of the enzymatic activity of PBP2, which is thought to synthesize peptidoglycan in the step of initiation of cell elongation [H]

COG id: COG0772

COG function: function code D; Bacterial cell division membrane protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ftsW/rodA/spoVE family [H]

Homologues:

Organism=Escherichia coli, GI1786853, Length=360, Percent_Identity=34.7222222222222, Blast_Score=182, Evalue=4e-47,
Organism=Escherichia coli, GI1786277, Length=328, Percent_Identity=31.4024390243902, Blast_Score=147, Evalue=1e-36,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001182
- InterPro:   IPR018365
- InterPro:   IPR011923 [H]

Pfam domain/function: PF01098 FTSW_RODA_SPOVE [H]

EC number: NA

Molecular weight: Translated: 41468; Mature: 41468

Theoretical pI: Translated: 9.67; Mature: 9.67

Prosite motif: PS00428 FTSW_RODA_SPOVE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.8 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.8 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHCHHHHHCCCC
>Mature Secondary Structure
MFDKFFINRKLLKELDYSMIIISVAIMIFSALNIYSATHMKYGTSFFQKQLIWLAVGLII
CCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IYVVLIFDYIIIENYANIFYWFTIFLLILNDTVLKKTVNGAGSWLKLGPISIQPSEFAKM
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCHHHHHHH
ALIIMLAKKLDDMEGEINNLRNFFTLAFYAVIPMILIVIQPDMGMTMVFFFTVLGMFFVA
HHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHH
GLDGKVISGGLAGLTALVAIIWNSPLMQQYWKNRLTSFLHPEADELNTGLQLVQSKIGIG
CCCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCC
SGGFLGKGFLKGTQIAGGYIPEAHTDFIFSVIGEEWGFIGAAILLIFYGILIYKFIKTAK
CCCCCCCCHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
NSKDIFGTMVTIGVTASFMFSILQNIGMTIGIVPITGIALPFMSYGGSSSLNNFLALALV
CCHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEHHHHHHHHHHHHCCCCCHHHHHHHHHHH
LNINMRRKKINF
HHCHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]