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The map label for this gene is ribD [H]

Identifier: 148380824

GI number: 148380824

Start: 3046774

End: 3047871

Strand: Reverse

Name: ribD [H]

Synonym: CBO2866

Alternate gene names: 148380824

Gene position: 3047871-3046774 (Counterclockwise)

Preceding gene: 148380825

Following gene: 148380823

Centisome position: 78.41

GC content: 30.97

Gene sequence:

>1098_bases
ATGGAAGATTATAATTTTTATATGGAAAAAGCCTTGAAACTAGCTGAAAGAGGTGAGGGTAAAGTTAATCCTAATCCTAA
AGTAGGAGCTATAGTAGTTAATAACAACAAAATAATTGGAGAAGGTTATCACAAATATTTTGGAGGACCTCATGCAGAAG
TTTATGCTCTTAAAGAAGCAGGAGAAAAGGCTAAAGGGGCTACTATATATGTTACATTAGAGCCCTGCTCACATTATGGT
AAAACTCCTCCCTGTGCAGAGTCTATAGTAAAGATGGGAATATCTAAGGCTATTATAGCTATGAAAGATCCCAATCCTTT
AGTTGAGGGTAGAGGGATAGATATTTTAAAGCAAAATGGAATAGAAGTTATAACAGGGATTATGGAAAAAGAAAGTAAAA
AATTAAATGAAGTATTTATAAAATACATAACTAAAAAGAAACCTTTTGTAGTTTTAAAAACTGCTTCTACCTTAGATGGC
AAGATTGCTACAAAAACAGGAGAATCAAAATGGATAACAGGAGAAGAGGCAAGATATAAAGTACATCAAATAAGAAATGA
TTTGTCAGGAATAATGGTAGGAATAGGGACAATTATAAAAGATAATCCTCTTTTAAATACAAGAATAGAAAGAGGAAGAA
GTCCAAAAGCAATAATAGTAGATTCTAGTCTTAGAATTCCATTAGAGTCTAAAATATTAGAAACTCTTAATGAAAGAACT
ATTTATATAGCAACAACTAAAAAACATAACAATTTTTCAAAAAAGAATGCTTTAGAAAATTTAGGGGCTAAGGTTTTAGA
GTTTGAGGAAAATGAAGAGGGAAAAGTTCCATTGAATGAATTAATGCAATATTTAGGATCAGAAGGAGTGGATAGCATTC
TTTTAGAGGGAGGCAGCACATTAAATTTTTCTGCACTAAAAGAAGGGATAGTAGATAAAGTTATGTGTTTTATAGCACCC
AAGATAATGGGAGGACAGGATTCAAAAAATATGATAGGTGGAAATGGGGTAGAAAGTTTAAAAGATATATTTAATCTACA
AAACTTAAAATTTGAAAAAATAGGGCAGGATATACTTATTGAAGGCTATGTATATTAG

Upstream 100 bases:

>100_bases
TTTAAAATTGTATACCAAAGCAAAAATTTAATACAAAAATGTATTTATATAATTACGATATTTGAGATTAAACAATAGCT
TTAAAGGCGGTGTATTTAAA

Downstream 100 bases:

>100_bases
AAAAGAGGGTGTTAGTTTGTTTACTGGCATAGTTGAGGAAGTCGGAAGAATATTAAAAATAGAGGAAGGAAAAGACTTTC
TTCACATCACCATAGAAGGA

Product: riboflavin biosynthesis protein RibD

Products: NA

Alternate protein names: Diaminohydroxyphosphoribosylaminopyrimidine deaminase; DRAP deaminase; Riboflavin-specific deaminase; 5-amino-6-(5-phosphoribosylamino)uracil reductase; HTP reductase [H]

Number of amino acids: Translated: 365; Mature: 365

Protein sequence:

>365_residues
MEDYNFYMEKALKLAERGEGKVNPNPKVGAIVVNNNKIIGEGYHKYFGGPHAEVYALKEAGEKAKGATIYVTLEPCSHYG
KTPPCAESIVKMGISKAIIAMKDPNPLVEGRGIDILKQNGIEVITGIMEKESKKLNEVFIKYITKKKPFVVLKTASTLDG
KIATKTGESKWITGEEARYKVHQIRNDLSGIMVGIGTIIKDNPLLNTRIERGRSPKAIIVDSSLRIPLESKILETLNERT
IYIATTKKHNNFSKKNALENLGAKVLEFEENEEGKVPLNELMQYLGSEGVDSILLEGGSTLNFSALKEGIVDKVMCFIAP
KIMGGQDSKNMIGGNGVESLKDIFNLQNLKFEKIGQDILIEGYVY

Sequences:

>Translated_365_residues
MEDYNFYMEKALKLAERGEGKVNPNPKVGAIVVNNNKIIGEGYHKYFGGPHAEVYALKEAGEKAKGATIYVTLEPCSHYG
KTPPCAESIVKMGISKAIIAMKDPNPLVEGRGIDILKQNGIEVITGIMEKESKKLNEVFIKYITKKKPFVVLKTASTLDG
KIATKTGESKWITGEEARYKVHQIRNDLSGIMVGIGTIIKDNPLLNTRIERGRSPKAIIVDSSLRIPLESKILETLNERT
IYIATTKKHNNFSKKNALENLGAKVLEFEENEEGKVPLNELMQYLGSEGVDSILLEGGSTLNFSALKEGIVDKVMCFIAP
KIMGGQDSKNMIGGNGVESLKDIFNLQNLKFEKIGQDILIEGYVY
>Mature_365_residues
MEDYNFYMEKALKLAERGEGKVNPNPKVGAIVVNNNKIIGEGYHKYFGGPHAEVYALKEAGEKAKGATIYVTLEPCSHYG
KTPPCAESIVKMGISKAIIAMKDPNPLVEGRGIDILKQNGIEVITGIMEKESKKLNEVFIKYITKKKPFVVLKTASTLDG
KIATKTGESKWITGEEARYKVHQIRNDLSGIMVGIGTIIKDNPLLNTRIERGRSPKAIIVDSSLRIPLESKILETLNERT
IYIATTKKHNNFSKKNALENLGAKVLEFEENEEGKVPLNELMQYLGSEGVDSILLEGGSTLNFSALKEGIVDKVMCFIAP
KIMGGQDSKNMIGGNGVESLKDIFNLQNLKFEKIGQDILIEGYVY

Specific function: Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate [H]

COG id: COG1985

COG function: function code H; Pyrimidine reductase, riboflavin biosynthesis

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the HTP reductase family [H]

Homologues:

Organism=Escherichia coli, GI1786616, Length=374, Percent_Identity=37.1657754010695, Blast_Score=275, Evalue=5e-75,
Organism=Escherichia coli, GI145693172, Length=151, Percent_Identity=30.4635761589404, Blast_Score=74, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016192
- InterPro:   IPR002125
- InterPro:   IPR016193
- InterPro:   IPR004794
- InterPro:   IPR011549
- InterPro:   IPR002734 [H]

Pfam domain/function: PF00383 dCMP_cyt_deam_1; PF01872 RibD_C [H]

EC number: =3.5.4.26; =1.1.1.193 [H]

Molecular weight: Translated: 40298; Mature: 40298

Theoretical pI: Translated: 8.88; Mature: 8.88

Prosite motif: PS00903 CYT_DCMP_DEAMINASES

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEDYNFYMEKALKLAERGEGKVNPNPKVGAIVVNNNKIIGEGYHKYFGGPHAEVYALKEA
CCCHHHHHHHHHHHHHCCCCCCCCCCCEEEEEEECCEEECCCHHHHCCCCCCEEEEEHHC
GEKAKGATIYVTLEPCSHYGKTPPCAESIVKMGISKAIIAMKDPNPLVEGRGIDILKQNG
CCCCCCCEEEEEECCHHCCCCCCHHHHHHHHHCCHHEEEEECCCCCCCCCCCCEEEHHCC
IEVITGIMEKESKKLNEVFIKYITKKKPFVVLKTASTLDGKIATKTGESKWITGEEARYK
HHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCEEEECCCCCCEECCHHHHHH
VHQIRNDLSGIMVGIGTIIKDNPLLNTRIERGRSPKAIIVDSSLRIPLESKILETLNERT
HHHHHHHHHHHHHHHHHHHCCCCCCHHHHHCCCCCCEEEEECCCCCCHHHHHHHHHCCCE
IYIATTKKHNNFSKKNALENLGAKVLEFEENEEGKVPLNELMQYLGSEGVDSILLEGGST
EEEEEECCCCCCHHHHHHHHCCCEEEEECCCCCCCCCHHHHHHHHCCCCCCHHHHCCCCC
LNFSALKEGIVDKVMCFIAPKIMGGQDSKNMIGGNGVESLKDIFNLQNLKFEKIGQDILI
CCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHCCCCHHHCCCEEEE
EGYVY
EEECC
>Mature Secondary Structure
MEDYNFYMEKALKLAERGEGKVNPNPKVGAIVVNNNKIIGEGYHKYFGGPHAEVYALKEA
CCCHHHHHHHHHHHHHCCCCCCCCCCCEEEEEEECCEEECCCHHHHCCCCCCEEEEEHHC
GEKAKGATIYVTLEPCSHYGKTPPCAESIVKMGISKAIIAMKDPNPLVEGRGIDILKQNG
CCCCCCCEEEEEECCHHCCCCCCHHHHHHHHHCCHHEEEEECCCCCCCCCCCCEEEHHCC
IEVITGIMEKESKKLNEVFIKYITKKKPFVVLKTASTLDGKIATKTGESKWITGEEARYK
HHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCEEEECCCCCCEECCHHHHHH
VHQIRNDLSGIMVGIGTIIKDNPLLNTRIERGRSPKAIIVDSSLRIPLESKILETLNERT
HHHHHHHHHHHHHHHHHHHCCCCCCHHHHHCCCCCCEEEEECCCCCCHHHHHHHHHCCCE
IYIATTKKHNNFSKKNALENLGAKVLEFEENEEGKVPLNELMQYLGSEGVDSILLEGGST
EEEEEECCCCCCHHHHHHHHCCCEEEEECCCCCCCCCHHHHHHHHCCCCCCHHHHCCCCC
LNFSALKEGIVDKVMCFIAPKIMGGQDSKNMIGGNGVESLKDIFNLQNLKFEKIGQDILI
CCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHCCCCHHHCCCEEEE
EGYVY
EEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8522537 [H]