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The map label for this gene is cutS [H]

Identifier: 148380808

GI number: 148380808

Start: 3026879

End: 3027367

Strand: Reverse

Name: cutS [H]

Synonym: CBO2850

Alternate gene names: 148380808

Gene position: 3027367-3026879 (Counterclockwise)

Preceding gene: 148380809

Following gene: 148380807

Centisome position: 77.89

GC content: 35.38

Gene sequence:

>489_bases
ATGATGGAGGTATTGAGTAAAACAATAATAACCTTAAATATTAATGGAGAATATAAAGAGGTTGTCGCAAAACCCTCAGA
CATTTTATTGCACACTCTTCGAAATGAACTAGGACTTACGGGGGCTAAGCCATCTTGTGAAAATGGAGATTGTGGTGCAT
GTACTATTCTTGTAGATGGATGGCCTATAAAATCTTGTCTAATGCTAACAGTTGAGGCCATAGGTAAAAAAATAGTTACT
GTTGAAGGCTTGAAAAATGCACCAATACAAAAAGCTTTTGTAGATAACTGGGGGTTTCAATGTGGATATTGCACATCAGG
GTTTTTAATGGTTTGCCATGCCTTAGCTAATATACATCCGGATGCGGATGACTATGTAATAGAGCAATGGTTGCAATCAA
ATCTTTGCCGATGTACTGGATATGAAGAGATAAAAACTGCTATTAAATCAGTTATATCAGATAACCAATCTGAAAATAAC
AGTATATAA

Upstream 100 bases:

>100_bases
GATGTAATATTAAATGATTTAGCTGGATCTGCTGGTTTTAGAAAATTTATGTTACAAAAAATGCTTGCAAAAGTTTTAGA
GAAATTGGAGGGATAAGTGA

Downstream 100 bases:

>100_bases
TGGGACTAAAAGGCTTAATTAAGAAGAGAATATACAAAAAAGAAGGCATATTTATTTATAGGCTTTCTTTTTTTATTCAC
AAACACAGAATATTCGGTAC

Product: dehydrogenase, [2Fe-2S] binding subunit

Products: NA

Alternate protein names: CO dehydrogenase subunit S; CO-DH S [H]

Number of amino acids: Translated: 162; Mature: 162

Protein sequence:

>162_residues
MMEVLSKTIITLNINGEYKEVVAKPSDILLHTLRNELGLTGAKPSCENGDCGACTILVDGWPIKSCLMLTVEAIGKKIVT
VEGLKNAPIQKAFVDNWGFQCGYCTSGFLMVCHALANIHPDADDYVIEQWLQSNLCRCTGYEEIKTAIKSVISDNQSENN
SI

Sequences:

>Translated_162_residues
MMEVLSKTIITLNINGEYKEVVAKPSDILLHTLRNELGLTGAKPSCENGDCGACTILVDGWPIKSCLMLTVEAIGKKIVT
VEGLKNAPIQKAFVDNWGFQCGYCTSGFLMVCHALANIHPDADDYVIEQWLQSNLCRCTGYEEIKTAIKSVISDNQSENN
SI
>Mature_162_residues
MMEVLSKTIITLNINGEYKEVVAKPSDILLHTLRNELGLTGAKPSCENGDCGACTILVDGWPIKSCLMLTVEAIGKKIVT
VEGLKNAPIQKAFVDNWGFQCGYCTSGFLMVCHALANIHPDADDYVIEQWLQSNLCRCTGYEEIKTAIKSVISDNQSENN
SI

Specific function: Catalyzes the oxidation of carbon monoxide to carbon dioxide [H]

COG id: COG2080

COG function: function code C; Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS/CutS homologs

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 2Fe-2S ferredoxin-type domain [H]

Homologues:

Organism=Homo sapiens, GI91823271, Length=159, Percent_Identity=32.7044025157233, Blast_Score=67, Evalue=6e-12,
Organism=Escherichia coli, GI1786480, Length=169, Percent_Identity=35.5029585798817, Blast_Score=106, Evalue=8e-25,
Organism=Escherichia coli, GI1789232, Length=146, Percent_Identity=41.7808219178082, Blast_Score=92, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI17539860, Length=161, Percent_Identity=36.0248447204969, Blast_Score=100, Evalue=3e-22,
Organism=Caenorhabditis elegans, GI17540638, Length=162, Percent_Identity=38.2716049382716, Blast_Score=98, Evalue=2e-21,
Organism=Caenorhabditis elegans, GI32566215, Length=163, Percent_Identity=34.9693251533742, Blast_Score=97, Evalue=4e-21,
Organism=Drosophila melanogaster, GI17737937, Length=162, Percent_Identity=32.7160493827161, Blast_Score=87, Evalue=5e-18,
Organism=Drosophila melanogaster, GI24647197, Length=168, Percent_Identity=37.5, Blast_Score=86, Evalue=8e-18,
Organism=Drosophila melanogaster, GI24647195, Length=168, Percent_Identity=37.5, Blast_Score=86, Evalue=8e-18,
Organism=Drosophila melanogaster, GI24647199, Length=142, Percent_Identity=39.4366197183099, Blast_Score=84, Evalue=4e-17,
Organism=Drosophila melanogaster, GI24647201, Length=161, Percent_Identity=38.5093167701863, Blast_Score=84, Evalue=4e-17,
Organism=Drosophila melanogaster, GI24647193, Length=165, Percent_Identity=35.7575757575758, Blast_Score=82, Evalue=2e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002888
- InterPro:   IPR012675
- InterPro:   IPR001041 [H]

Pfam domain/function: PF00111 Fer2; PF01799 Fer2_2 [H]

EC number: =1.2.99.2 [H]

Molecular weight: Translated: 17743; Mature: 17743

Theoretical pI: Translated: 4.75; Mature: 4.75

Prosite motif: PS00197 2FE2S_FER_1 ; PS51085 2FE2S_FER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

5.6 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
8.0 %Cys+Met (Translated Protein)
5.6 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
8.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMEVLSKTIITLNINGEYKEVVAKPSDILLHTLRNELGLTGAKPSCENGDCGACTILVDG
CHHHHCCEEEEEEECCHHHHHHCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEEECC
WPIKSCLMLTVEAIGKKIVTVEGLKNAPIQKAFVDNWGFQCGYCTSGFLMVCHALANIHP
CCHHHHHHHHHHHHCCEEEEECCCCCCCHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCC
DADDYVIEQWLQSNLCRCTGYEEIKTAIKSVISDNQSENNSI
CCHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure
MMEVLSKTIITLNINGEYKEVVAKPSDILLHTLRNELGLTGAKPSCENGDCGACTILVDG
CHHHHCCEEEEEEECCHHHHHHCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEEECC
WPIKSCLMLTVEAIGKKIVTVEGLKNAPIQKAFVDNWGFQCGYCTSGFLMVCHALANIHP
CCHHHHHHHHHHHHCCEEEEECCCCCCCHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCC
DADDYVIEQWLQSNLCRCTGYEEIKTAIKSVISDNQSENNSI
CCHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10482497; 2818128; 10966817; 11076018 [H]