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The map label for this gene is ntpD [H]

Identifier: 148380579

GI number: 148380579

Start: 2772103

End: 2772762

Strand: Reverse

Name: ntpD [H]

Synonym: CBO2623

Alternate gene names: 148380579

Gene position: 2772762-2772103 (Counterclockwise)

Preceding gene: 148380580

Following gene: 148380578

Centisome position: 71.34

GC content: 31.06

Gene sequence:

>660_bases
GTGATCTTTATGAAATTAAATGTAAATCCTACTAGAATGGAGCTCACTAAACTTAAAAAGAGGTTAACAACAGCCACCAG
AGGACATAAACTCTTAAAAGATAAGCAAGATGAGCTTATGAGAAGATTCATAGGTATGATAAAAAAGAATAATGAACTTA
GAAAAGATGTAGAAAAGGAATTAGAGGGATCTTTTAAAGACTTTTTAATGGCTAGCGCGGTTATGTCTCCAGAGTTTTTG
GAGGAAGCCGTAGCTTATCCAAAGGAAAGTATTTCTGTAGATGTTAAAAAGCAAAATATAATGAGTGTTAATGTGCCTGT
GTTTGACTTTAAAAGAAAGTTAGAAGGAGATAAAGGAAGTATATTCCCTTATGGTTTTGCTAATACTTCTGCTGAATTAG
ATGGTGCTATAGAAAAATTATATGGTATATTACCTAAGCTTTTAGAATTAGCTAAAGTAGAAAAAGCATGTCAACTAATG
GCGGATGAAATTGAAAAAACTAGAAGAAGAGTTAACGCTCTAGAATATATGACTATACCTCAACTAGAGGAAACTATAAA
ATTTATACAAATGAAGTTAGATGAAAATGAAAGAAGTACAGTAACAAGACTTATGAAAATCAAGAGTATGATGGAAGAAA
AGCAAAGTAATATGGTATAA

Upstream 100 bases:

>100_bases
ATCTTACCTAAGTCAGAGCTTAAGAGAATAAGAGATGAATATCTAGAAAAATATTTAAATAAAGCTGAAGAAAGCAAATA
ATAACCATTAAAAGGGATGA

Downstream 100 bases:

>100_bases
AAAAAGCAGCGAAAATCGCTGCTTTTTTTATACAAAGTAAGTATGTTTTGCTTTAAAATTAATGAGTAGCTATATATGGT
AAAAATAGTTTTAATAAAAT

Product: V-type ATP synthase subunit D

Products: ADP; phosphate; H+

Alternate protein names: V-ATPase subunit D [H]

Number of amino acids: Translated: 219; Mature: 219

Protein sequence:

>219_residues
MIFMKLNVNPTRMELTKLKKRLTTATRGHKLLKDKQDELMRRFIGMIKKNNELRKDVEKELEGSFKDFLMASAVMSPEFL
EEAVAYPKESISVDVKKQNIMSVNVPVFDFKRKLEGDKGSIFPYGFANTSAELDGAIEKLYGILPKLLELAKVEKACQLM
ADEIEKTRRRVNALEYMTIPQLEETIKFIQMKLDENERSTVTRLMKIKSMMEEKQSNMV

Sequences:

>Translated_219_residues
MIFMKLNVNPTRMELTKLKKRLTTATRGHKLLKDKQDELMRRFIGMIKKNNELRKDVEKELEGSFKDFLMASAVMSPEFL
EEAVAYPKESISVDVKKQNIMSVNVPVFDFKRKLEGDKGSIFPYGFANTSAELDGAIEKLYGILPKLLELAKVEKACQLM
ADEIEKTRRRVNALEYMTIPQLEETIKFIQMKLDENERSTVTRLMKIKSMMEEKQSNMV
>Mature_219_residues
MIFMKLNVNPTRMELTKLKKRLTTATRGHKLLKDKQDELMRRFIGMIKKNNELRKDVEKELEGSFKDFLMASAVMSPEFL
EEAVAYPKESISVDVKKQNIMSVNVPVFDFKRKLEGDKGSIFPYGFANTSAELDGAIEKLYGILPKLLELAKVEKACQLM
ADEIEKTRRRVNALEYMTIPQLEETIKFIQMKLDENERSTVTRLMKIKSMMEEKQSNMV

Specific function: Produces ATP from ADP in the presence of a proton gradient across the membrane [H]

COG id: COG1394

COG function: function code C; Archaeal/vacuolar-type H+-ATPase subunit D

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the V-ATPase D subunit family [H]

Homologues:

Organism=Homo sapiens, GI7706757, Length=207, Percent_Identity=31.4009661835749, Blast_Score=79, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI17553636, Length=211, Percent_Identity=32.7014218009479, Blast_Score=82, Evalue=2e-16,
Organism=Saccharomyces cerevisiae, GI6320784, Length=207, Percent_Identity=28.0193236714976, Blast_Score=71, Evalue=1e-13,
Organism=Drosophila melanogaster, GI20128937, Length=217, Percent_Identity=31.7972350230415, Blast_Score=84, Evalue=7e-17,
Organism=Drosophila melanogaster, GI21355551, Length=209, Percent_Identity=33.0143540669856, Blast_Score=83, Evalue=2e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002699 [H]

Pfam domain/function: PF01813 ATP-synt_D [H]

EC number: 3.6.3.14

Molecular weight: Translated: 25395; Mature: 25395

Theoretical pI: Translated: 9.83; Mature: 9.83

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
6.8 %Met     (Translated Protein)
7.3 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
6.8 %Met     (Mature Protein)
7.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIFMKLNVNPTRMELTKLKKRLTTATRGHKLLKDKQDELMRRFIGMIKKNNELRKDVEKE
CEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHCCCHHHHHHHHH
LEGSFKDFLMASAVMSPEFLEEAVAYPKESISVDVKKQNIMSVNVPVFDFKRKLEGDKGS
HHHHHHHHHHHHHHCCHHHHHHHHHCCHHHCEEEEECCCEEEECCCHHHHHHHHCCCCCC
IFPYGFANTSAELDGAIEKLYGILPKLLELAKVEKACQLMADEIEKTRRRVNALEYMTIP
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCH
QLEETIKFIQMKLDENERSTVTRLMKIKSMMEEKQSNMV
HHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MIFMKLNVNPTRMELTKLKKRLTTATRGHKLLKDKQDELMRRFIGMIKKNNELRKDVEKE
CEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHCCCHHHHHHHHH
LEGSFKDFLMASAVMSPEFLEEAVAYPKESISVDVKKQNIMSVNVPVFDFKRKLEGDKGS
HHHHHHHHHHHHHHCCHHHHHHHHHCCHHHCEEEEECCCEEEECCCHHHHHHHHCCCCCC
IFPYGFANTSAELDGAIEKLYGILPKLLELAKVEKACQLMADEIEKTRRRVNALEYMTIP
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCH
QLEETIKFIQMKLDENERSTVTRLMKIKSMMEEKQSNMV
HHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; H2O; H+

Specific reaction: ATP + H2O + H+(in) = ADP + phosphate + H+(out)

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA