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The map label for this gene is prdA1 [H]

Identifier: 148380421

GI number: 148380421

Start: 2596125

End: 2598239

Strand: Reverse

Name: prdA1 [H]

Synonym: CBO2464

Alternate gene names: 148380421

Gene position: 2598239-2596125 (Counterclockwise)

Preceding gene: 148380422

Following gene: 148380420

Centisome position: 66.85

GC content: 34.42

Gene sequence:

>2115_bases
ATGTCAATGACACCAGAGCATGCAGAGGCGTTAAAGAATGAATCTGCAGTAGTATGTTGTAGAGCAGAAGAGGGAACAAT
ATTAACTGCTGACAACTTAGAAGATCCAGAAATATTCCCAGATATGGTAGACTCAGGTCTATTAACTATTCCAGCTGATT
GTTTAAAAGTTGGGGAAGTAATAGGAGCTAAATTGTTAAAAACTGTAGATTCATTAACACCATTAACTCCAGATATAATT
GAGGGAGCAAAAACAATAGGTGGTTCAGAAGAAAAGGCTGAAGAAATTTCAGAAGAATTAACTGAAGAAGATGAAAAAGC
AGTTCTAAAATATAACTTAAAAGCAGGAGATACTATAAAAGCTAGTGATCTAGAAAATCCAATGCATTTTGAAAAACTTG
TAGATTCTCTTTTACTAACATTAGATGAAAGAGTTCTTACAAGAAAAGAAGTAGTTGGAGCAACTTTATCAGTTGATACG
CCAGCTTTAACTCCTGTAACACCTGATATATTAGAAGGATTTGAGGAGGAAGTAAACATGAGTGCTGATACACAAGCAAC
AATAAGTGGTGGAACTTTAAGAATCAGAATAGCCGAAGGAAAAGGAATTGACATCGAAGTTCCTTTAAATGGAAATGTAG
GTACAGGAAAATCAATAGCTGTTCCAGCAGTAAAAGCTGAAAAAGGCACAGTAACTGCAGCGCCAGTAGCAGTAGAAGCT
AAAAAAGAAGTTAAATTAGAAGAAAAAATAGTAAGATCAGTTACAAGAAAACACTATAAAATAGATAAAGTAGAATTAGC
TAAAGAAACTAAAATTGAAGGAACAACTCTTTATATAAGAGAAAACATCTGTGAAGATGCATTCAATGTAGACCAATTAG
TTAAAGATATAAAATTAGAAATAATAACTCCAGATAAGTACAACACTTATAGTGAAACTATAATGGACGTACAACCAATA
GCTACTAAAGAAGGTTCAGATGCTAAGTTAGGTGAAGGTGTTACAAGAGTTATAGATGGAGCTATTGTAATGGTAACTGG
CATAGATGAAGACGGAGTTCAAGTTGGTGAATTCGGTTCTTCAGAAGGTATATTAGAAGAAAACATTATGTGGGGAAGAC
CAGGTGCTCCTGATAAAGGTGAAATATTCATCAAAACTCAAGTAACTATAAAAAGAGGAACAGGAATGGAAAGACCAGGT
CCATTAGCTGCTCACAAAGCAACAGATTTTATAACTCAAGAAATCAGAGAAGCTTTAAAAGCTGTTGAAGATGATTCATT
AGTAGTTAACACTGAAACTTTTGAACAAGTAAGAAGACCAGGAAAGAAAAAAGTTGTAGTTGTTAAAGAAATAATGGGTC
AAGGTGCTATGCACGATAACTTAATATTACCATTAGAACCAGTTGGGGTAATAGGAGCTAAACCAAACGTTGATTTAGGA
AACGTTCCAGTAATGCTTGCGCCAACAGAAGTATTAGATGGTGGTATCCATGCATTAACTTGTATTGGACCTGCTTCTAA
AGAATGTTCAAGACACTACTTTAGAGAACCACTTGTAATGGAATGTATGCAAGATGAAGAAGTAGATTTAGCAGGAGTTA
TATTTGTAGGAAGTCCACAAATCAACAGTGAAAAATTCTATGTATCTGAAAGATTAGGAATGATGGTAGAAGCTATGGAT
GTTGATGGTGCTTTTGTTACAACTGAAGGTTTTGGAAATAACCACATTGACTTTGCAAGCCACGTAGAACAAATAGGTAT
GAGAGGTGTTCCTTGTGTAGCATTCTCATTCTGCGCAGTTCAAGGCGCTCTAGTTGTTGGTAACAAACACATGAAATATA
TGGTAGATAACAACAAATCAGAAGGTGGAATAGAAAACGAAGTATTATCTTGTAATACATTATGTAAAGAAGATGCTGTA
AGAGGCCTTGCAATGATTAAAGCAGCTATGTCTGGAGAAGAAGTTAAAAAGCCAGAAAGAGCTTGGAATGCAAATGTTAA
AGAAAATAACATTGAAATGATAGAAAAATCTACTGGAAATAAAATTGATAGAGTTTTAAATGAAACTTCAATACCAATGA
GCGAAAAGAGAAAAGAAAAATACGCTACAAAGTAG

Upstream 100 bases:

>100_bases
ATCATCATACTGATCATATATTTAGAACTATTGATTACACATTAACAAGAAGACTTCCACAGGAATAACAAAAAAATAAA
AAAATAGGAGGTTATGTCTT

Downstream 100 bases:

>100_bases
GGATATAGATGGATTTAAAATATGGTGATAAAATCCTAGAAATGCAAGGTGTTATTGTAGACGTATCCGATGGAGCAGTA
GCCATAGATTTCAAAGGAAG

Product: proline reductase protein

Products: NA

Alternate protein names: D-proline reductase 45 kDa subunit; D-proline reductase 23 kDa subunit [H]

Number of amino acids: Translated: 704; Mature: 703

Protein sequence:

>704_residues
MSMTPEHAEALKNESAVVCCRAEEGTILTADNLEDPEIFPDMVDSGLLTIPADCLKVGEVIGAKLLKTVDSLTPLTPDII
EGAKTIGGSEEKAEEISEELTEEDEKAVLKYNLKAGDTIKASDLENPMHFEKLVDSLLLTLDERVLTRKEVVGATLSVDT
PALTPVTPDILEGFEEEVNMSADTQATISGGTLRIRIAEGKGIDIEVPLNGNVGTGKSIAVPAVKAEKGTVTAAPVAVEA
KKEVKLEEKIVRSVTRKHYKIDKVELAKETKIEGTTLYIRENICEDAFNVDQLVKDIKLEIITPDKYNTYSETIMDVQPI
ATKEGSDAKLGEGVTRVIDGAIVMVTGIDEDGVQVGEFGSSEGILEENIMWGRPGAPDKGEIFIKTQVTIKRGTGMERPG
PLAAHKATDFITQEIREALKAVEDDSLVVNTETFEQVRRPGKKKVVVVKEIMGQGAMHDNLILPLEPVGVIGAKPNVDLG
NVPVMLAPTEVLDGGIHALTCIGPASKECSRHYFREPLVMECMQDEEVDLAGVIFVGSPQINSEKFYVSERLGMMVEAMD
VDGAFVTTEGFGNNHIDFASHVEQIGMRGVPCVAFSFCAVQGALVVGNKHMKYMVDNNKSEGGIENEVLSCNTLCKEDAV
RGLAMIKAAMSGEEVKKPERAWNANVKENNIEMIEKSTGNKIDRVLNETSIPMSEKRKEKYATK

Sequences:

>Translated_704_residues
MSMTPEHAEALKNESAVVCCRAEEGTILTADNLEDPEIFPDMVDSGLLTIPADCLKVGEVIGAKLLKTVDSLTPLTPDII
EGAKTIGGSEEKAEEISEELTEEDEKAVLKYNLKAGDTIKASDLENPMHFEKLVDSLLLTLDERVLTRKEVVGATLSVDT
PALTPVTPDILEGFEEEVNMSADTQATISGGTLRIRIAEGKGIDIEVPLNGNVGTGKSIAVPAVKAEKGTVTAAPVAVEA
KKEVKLEEKIVRSVTRKHYKIDKVELAKETKIEGTTLYIRENICEDAFNVDQLVKDIKLEIITPDKYNTYSETIMDVQPI
ATKEGSDAKLGEGVTRVIDGAIVMVTGIDEDGVQVGEFGSSEGILEENIMWGRPGAPDKGEIFIKTQVTIKRGTGMERPG
PLAAHKATDFITQEIREALKAVEDDSLVVNTETFEQVRRPGKKKVVVVKEIMGQGAMHDNLILPLEPVGVIGAKPNVDLG
NVPVMLAPTEVLDGGIHALTCIGPASKECSRHYFREPLVMECMQDEEVDLAGVIFVGSPQINSEKFYVSERLGMMVEAMD
VDGAFVTTEGFGNNHIDFASHVEQIGMRGVPCVAFSFCAVQGALVVGNKHMKYMVDNNKSEGGIENEVLSCNTLCKEDAV
RGLAMIKAAMSGEEVKKPERAWNANVKENNIEMIEKSTGNKIDRVLNETSIPMSEKRKEKYATK
>Mature_703_residues
SMTPEHAEALKNESAVVCCRAEEGTILTADNLEDPEIFPDMVDSGLLTIPADCLKVGEVIGAKLLKTVDSLTPLTPDIIE
GAKTIGGSEEKAEEISEELTEEDEKAVLKYNLKAGDTIKASDLENPMHFEKLVDSLLLTLDERVLTRKEVVGATLSVDTP
ALTPVTPDILEGFEEEVNMSADTQATISGGTLRIRIAEGKGIDIEVPLNGNVGTGKSIAVPAVKAEKGTVTAAPVAVEAK
KEVKLEEKIVRSVTRKHYKIDKVELAKETKIEGTTLYIRENICEDAFNVDQLVKDIKLEIITPDKYNTYSETIMDVQPIA
TKEGSDAKLGEGVTRVIDGAIVMVTGIDEDGVQVGEFGSSEGILEENIMWGRPGAPDKGEIFIKTQVTIKRGTGMERPGP
LAAHKATDFITQEIREALKAVEDDSLVVNTETFEQVRRPGKKKVVVVKEIMGQGAMHDNLILPLEPVGVIGAKPNVDLGN
VPVMLAPTEVLDGGIHALTCIGPASKECSRHYFREPLVMECMQDEEVDLAGVIFVGSPQINSEKFYVSERLGMMVEAMDV
DGAFVTTEGFGNNHIDFASHVEQIGMRGVPCVAFSFCAVQGALVVGNKHMKYMVDNNKSEGGIENEVLSCNTLCKEDAVR
GLAMIKAAMSGEEVKKPERAWNANVKENNIEMIEKSTGNKIDRVLNETSIPMSEKRKEKYATK

Specific function: D-proline reductase catalyzes the reductive cleavage of a C-N bond in D-proline resulting in the formation of 5- aminovalerate. The alpha subunit has been shown to bind D-proline, presumably via the pyruvoyl group [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015417 [H]

Pfam domain/function: PF09338 Gly_reductase [H]

EC number: =1.21.4.1 [H]

Molecular weight: Translated: 76412; Mature: 76281

Theoretical pI: Translated: 4.48; Mature: 4.48

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSMTPEHAEALKNESAVVCCRAEEGTILTADNLEDPEIFPDMVDSGLLTIPADCLKVGEV
CCCCHHHHHHHCCCCEEEEEECCCCCEEEECCCCCCCCCHHHHCCCCEECCHHHHHHHHH
IGAKLLKTVDSLTPLTPDIIEGAKTIGGSEEKAEEISEELTEEDEKAVLKYNLKAGDTIK
HHHHHHHHHHHHCCCCHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCEEEEEECCCCCEEE
ASDLENPMHFEKLVDSLLLTLDERVLTRKEVVGATLSVDTPALTPVTPDILEGFEEEVNM
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCEEECCCCCCCCCCHHHHHHHHHHCCC
SADTQATISGGTLRIRIAEGKGIDIEVPLNGNVGTGKSIAVPAVKAEKGTVTAAPVAVEA
CCCCEEEECCCEEEEEEECCCCEEEEEECCCCCCCCCEEEECEEECCCCCEEECCEEECC
KKEVKLEEKIVRSVTRKHYKIDKVELAKETKIEGTTLYIRENICEDAFNVDQLVKDIKLE
HHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCCEEEEEEHHHHHHHCCHHHHHHHCEEE
IITPDKYNTYSETIMDVQPIATKEGSDAKLGEGVTRVIDGAIVMVTGIDEDGVQVGEFGS
EECCCCCCCHHHHHHCCCCCCCCCCCCCCHHCCHHHHHCCEEEEEECCCCCCCEECCCCC
SEGILEENIMWGRPGAPDKGEIFIKTQVTIKRGTGMERPGPLAAHKATDFITQEIREALK
CCCCCCCCCEECCCCCCCCCCEEEEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHH
AVEDDSLVVNTETFEQVRRPGKKKVVVVKEIMGQGAMHDNLILPLEPVGVIGAKPNVDLG
HCCCCCEEEEHHHHHHHHCCCCCEEEEEHHHHCCCCCCCCEEEECCCCEEECCCCCCCCC
NVPVMLAPTEVLDGGIHALTCIGPASKECSRHYFREPLVMECMQDEEVDLAGVIFVGSPQ
CCCEEEECHHHHCCCCEEEEEECCCHHHHHHHHHCCCHHHHHCCCCCCCEEEEEEECCCC
INSEKFYVSERLGMMVEAMDVDGAFVTTEGFGNNHIDFASHVEQIGMRGVPCVAFSFCAV
CCCCEEEHHHHHCCEEEEEECCCEEEEECCCCCCCCHHHHHHHHHCCCCCHHHHHHHHHH
QGALVVGNKHMKYMVDNNKSEGGIENEVLSCNTLCKEDAVRGLAMIKAAMSGEEVKKPER
CCEEEECCCCEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHCCCHH
AWNANVKENNIEMIEKSTGNKIDRVLNETSIPMSEKRKEKYATK
HHCCCCCCCCHHHHHCCCCHHHHHHHHHCCCCHHHHHHHHCCCC
>Mature Secondary Structure 
SMTPEHAEALKNESAVVCCRAEEGTILTADNLEDPEIFPDMVDSGLLTIPADCLKVGEV
CCCHHHHHHHCCCCEEEEEECCCCCEEEECCCCCCCCCHHHHCCCCEECCHHHHHHHHH
IGAKLLKTVDSLTPLTPDIIEGAKTIGGSEEKAEEISEELTEEDEKAVLKYNLKAGDTIK
HHHHHHHHHHHHCCCCHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCEEEEEECCCCCEEE
ASDLENPMHFEKLVDSLLLTLDERVLTRKEVVGATLSVDTPALTPVTPDILEGFEEEVNM
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCEEECCCCCCCCCCHHHHHHHHHHCCC
SADTQATISGGTLRIRIAEGKGIDIEVPLNGNVGTGKSIAVPAVKAEKGTVTAAPVAVEA
CCCCEEEECCCEEEEEEECCCCEEEEEECCCCCCCCCEEEECEEECCCCCEEECCEEECC
KKEVKLEEKIVRSVTRKHYKIDKVELAKETKIEGTTLYIRENICEDAFNVDQLVKDIKLE
HHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCCEEEEEEHHHHHHHCCHHHHHHHCEEE
IITPDKYNTYSETIMDVQPIATKEGSDAKLGEGVTRVIDGAIVMVTGIDEDGVQVGEFGS
EECCCCCCCHHHHHHCCCCCCCCCCCCCCHHCCHHHHHCCEEEEEECCCCCCCEECCCCC
SEGILEENIMWGRPGAPDKGEIFIKTQVTIKRGTGMERPGPLAAHKATDFITQEIREALK
CCCCCCCCCEECCCCCCCCCCEEEEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHH
AVEDDSLVVNTETFEQVRRPGKKKVVVVKEIMGQGAMHDNLILPLEPVGVIGAKPNVDLG
HCCCCCEEEEHHHHHHHHCCCCCEEEEEHHHHCCCCCCCCEEEECCCCEEECCCCCCCCC
NVPVMLAPTEVLDGGIHALTCIGPASKECSRHYFREPLVMECMQDEEVDLAGVIFVGSPQ
CCCEEEECHHHHCCCCEEEEEECCCHHHHHHHHHCCCHHHHHCCCCCCCEEEEEEECCCC
INSEKFYVSERLGMMVEAMDVDGAFVTTEGFGNNHIDFASHVEQIGMRGVPCVAFSFCAV
CCCCEEEHHHHHCCEEEEEECCCEEEEECCCCCCCCHHHHHHHHHCCCCCHHHHHHHHHH
QGALVVGNKHMKYMVDNNKSEGGIENEVLSCNTLCKEDAVRGLAMIKAAMSGEEVKKPER
CCEEEECCCCEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHCCCHH
AWNANVKENNIEMIEKSTGNKIDRVLNETSIPMSEKRKEKYATK
HHCCCCCCCCHHHHHCCCCHHHHHHHHHCCCCHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10085076 [H]