Definition Clostridium botulinum A str. ATCC 3502, complete genome.
Accession NC_009495
Length 3,886,916

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The map label for this gene is abrB [H]

Identifier: 148380328

GI number: 148380328

Start: 2512004

End: 2512243

Strand: Reverse

Name: abrB [H]

Synonym: CBO2374

Alternate gene names: 148380328

Gene position: 2512243-2512004 (Counterclockwise)

Preceding gene: 148380329

Following gene: 148380327

Centisome position: 64.63

GC content: 30.0

Gene sequence:

>240_bases
ATGAAAAATATAGGAATAGTAAGAAAAGTAGACGAGTTAGGAAGGATAGTTATACCTAAAGAATTAAGAAAGGTCTTAAA
TATAGATGAAGGTGATGGACTAGAGATTTATACAGAAGGTGAGCAAATAATACTAAAAAAGTATGAGCCATGTTGCATAT
TCTGCGGAGAAGCTAAAGAGATTATAAACTTCAAAGGTAAAAATATTTGTAAAATCTGTTTAAAGGAGTTAGGCAAATAG

Upstream 100 bases:

>100_bases
GATTATATAACCATCATGAGGATTTAGATAAAGCCCTAAGAGCAGTAGGTAAAGAAATAATGCTATATGAATTAAATAAA
AATAAGGGAGAGATATAATT

Downstream 100 bases:

>100_bases
TGAGTATTGAAGATTATGTGAATTTAAAAATTAAAGAAATGGTAAATGATGCACATAGAAATGCAATAGATCATGGGTTT
TGGGAAGAAGAACAGAATAT

Product: SpoVT/AbrB family regulatory protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 79; Mature: 79

Protein sequence:

>79_residues
MKNIGIVRKVDELGRIVIPKELRKVLNIDEGDGLEIYTEGEQIILKKYEPCCIFCGEAKEIINFKGKNICKICLKELGK

Sequences:

>Translated_79_residues
MKNIGIVRKVDELGRIVIPKELRKVLNIDEGDGLEIYTEGEQIILKKYEPCCIFCGEAKEIINFKGKNICKICLKELGK
>Mature_79_residues
MKNIGIVRKVDELGRIVIPKELRKVLNIDEGDGLEIYTEGEQIILKKYEPCCIFCGEAKEIINFKGKNICKICLKELGK

Specific function: Ambiactive repressor and activator of the transcription of genes expressed during the transition state between vegetative growth and the onset of stationary phase and sporulation. It controls the expression of genes spovG and tycA. AbrB binds to the tycA

COG id: COG2002

COG function: function code K; Regulators of stationary/sporulation gene expression

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: To B.subtilis abh and spoVT [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006339
- InterPro:   IPR007159 [H]

Pfam domain/function: PF04014 SpoVT_AbrB [H]

EC number: NA

Molecular weight: Translated: 8996; Mature: 8996

Theoretical pI: Translated: 8.20; Mature: 8.20

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

6.3 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
7.6 %Cys+Met (Translated Protein)
6.3 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
7.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKNIGIVRKVDELGRIVIPKELRKVLNIDEGDGLEIYTEGEQIILKKYEPCCIFCGEAKE
CCCCCCEEEHHHCCCEECCHHHHHHHCCCCCCCEEEEECCCEEEEECCCCEEEEECCCHH
IINFKGKNICKICLKELGK
HHCCCCCHHHHHHHHHHCC
>Mature Secondary Structure
MKNIGIVRKVDELGRIVIPKELRKVLNIDEGDGLEIYTEGEQIILKKYEPCCIFCGEAKE
CCCCCCEEEHHHCCCEECCHHHHHHHCCCCCCCEEEEECCCEEEEECCCCEEEEECCCHH
IINFKGKNICKICLKELGK
HHCCCCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 3145384; 2554317; 7584024; 9384377; 2504584; 1908787 [H]