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The map label for this gene is opuBB [H]

Identifier: 148379598

GI number: 148379598

Start: 1776428

End: 1778014

Strand: Direct

Name: opuBB [H]

Synonym: CBO1637

Alternate gene names: 148379598

Gene position: 1776428-1778014 (Clockwise)

Preceding gene: 148379597

Following gene: 148379599

Centisome position: 45.7

GC content: 28.92

Gene sequence:

>1587_bases
TTGATGAATAATTTTATACAGCAATTAATACTTAAAAGATCAGAAATATTCTCTCTTTTAATAGAACATATAGAACTTAC
TTTAATAGCAGTTTTAATAGCAGTAGTTATTGGAGTGCCCCTTGGCATAATTATTACTAAAAATAAAAAGATAGCTAATA
TAGTAATAGGTTTTGCAAATTTAACACAAGCTATACCAAGCTTAGCTATTTTAGGCTTTTTAATACCTTTAATAGGTATA
GGATCAGCACCTGCTATAACTATGGTTGTTTTATATTCTATGCTACCAATATTAAAAAATACTTATACAGGAATTACTAA
TATAAATCCAGATATGCTAGAAGCAGCTAAAGGTTTAGGAATGACAAATACTCAAACTCTTAAATTAATAAAAATACCTT
TAGCAATGCCAATAATAATGGCAGGTGTAAGAATAGCATCAGTAACAGCCGTTGGACTTATGACTATAGCAGCCTTTGTA
GGAGCAGGTGGACTTGGATACTTAGTATTCTCAGGAATACAAACAGTAGATAATAATCTTATATTATTTGGTGCTATTCC
AGCTGCTATATTAGCTTTAATAATAGATTGGATAACAGGAAGAATAGAAGAGGCAACTATGCCAAATGGTATAAAAAAAG
CAGATGGTACAATGAAAGTAAAAGGAAATTCTTCAAATAAAAACAGGAAAAGAAATACTATAATAGCATCAATATTAGGA
GTTCTTATAGTGTTAGCATTAATAGTTCCAAAGCTAATAGGACTAGGGGATAAAAAAGTAGTTATTGGTTCCAAAAACTT
TACAGAACAGATTATCTTAGGTAACATATTGGAAGAGTTAATTGATAATAAAACAGATATAGATGTTGAAACAAAGTTAA
ATTTAGGAGGAACTCAAGTAAGCTTTAATGCACTAAAAACTGGCGGAATAGATATGTATGTTGAATATACAGGTACTGCA
TATGGAAATATGCTAAATATAAAAAAACCTAATAGAGATAGACAGGCGGTTTATAATACAGTCAAAAAGGAGTTTAAGGA
AAAGTTTGGAATTGAAGTCTTAAACCCTATAGGTTTTAACAATACTTATGTAATGGCAACTACAAAAGAAATTGCACAAA
AATATAATTTAAAAACCACATCAGATTTAGCAAATGTATCAAGTAAAATGATATTAGGACCAACAATAGAATTTGCAAAT
AGAGAAGATGGGATTATAGGTCTTAATAAAGCATATAATATGAATTTTAAGGCTGTTAAACCAATAGATGGTGGATTAAG
GTATAAAGCTTTAGTTAATAATGAAACTCAAATTATAGATGCTTTTACAACAGATGGATTAATAGAGCAGTTTAATTTAG
TTCTTTTAGAGGATGACAAGCATTTTTTCCCAGATTATTATGCAGTTCCAATTGTAAAAGAAGAAACATTAAAGAAGTTC
CCAGAACTTAAAGAAGTTTTAGGAGCACTAGATGGAAAGATTACGGATGAAAAAATGAGAAAATTAAATTATGAAGTAGA
TGTAAATAAAAGAGATCCTAAAGAAGTAGCAAAAGAATTTTTGCAAAAAGAAGGGTTAATAGATTAA

Upstream 100 bases:

>100_bases
TTGCCTGTAAGTGATAGTGAAGGAAAACTTTTAGGGTTAATAACAAGAAGTAGTTTAATATCAGTTTTAAGTAGTCAATA
TATAGATATGGAGGGGATAA

Downstream 100 bases:

>100_bases
AATTATATACTAAAAATTATGTAAAGAGTTTAATTCTACATAATAAACTTAATACAGCATATTATTTAAAGCTTAATTAA
AGATCAGAAAATTTATTTTA

Product: glycine betaine/L-proline ABC transporter, permease/glycine betaine/L-proline-binding protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 528; Mature: 528

Protein sequence:

>528_residues
MMNNFIQQLILKRSEIFSLLIEHIELTLIAVLIAVVIGVPLGIIITKNKKIANIVIGFANLTQAIPSLAILGFLIPLIGI
GSAPAITMVVLYSMLPILKNTYTGITNINPDMLEAAKGLGMTNTQTLKLIKIPLAMPIIMAGVRIASVTAVGLMTIAAFV
GAGGLGYLVFSGIQTVDNNLILFGAIPAAILALIIDWITGRIEEATMPNGIKKADGTMKVKGNSSNKNRKRNTIIASILG
VLIVLALIVPKLIGLGDKKVVIGSKNFTEQIILGNILEELIDNKTDIDVETKLNLGGTQVSFNALKTGGIDMYVEYTGTA
YGNMLNIKKPNRDRQAVYNTVKKEFKEKFGIEVLNPIGFNNTYVMATTKEIAQKYNLKTTSDLANVSSKMILGPTIEFAN
REDGIIGLNKAYNMNFKAVKPIDGGLRYKALVNNETQIIDAFTTDGLIEQFNLVLLEDDKHFFPDYYAVPIVKEETLKKF
PELKEVLGALDGKITDEKMRKLNYEVDVNKRDPKEVAKEFLQKEGLID

Sequences:

>Translated_528_residues
MMNNFIQQLILKRSEIFSLLIEHIELTLIAVLIAVVIGVPLGIIITKNKKIANIVIGFANLTQAIPSLAILGFLIPLIGI
GSAPAITMVVLYSMLPILKNTYTGITNINPDMLEAAKGLGMTNTQTLKLIKIPLAMPIIMAGVRIASVTAVGLMTIAAFV
GAGGLGYLVFSGIQTVDNNLILFGAIPAAILALIIDWITGRIEEATMPNGIKKADGTMKVKGNSSNKNRKRNTIIASILG
VLIVLALIVPKLIGLGDKKVVIGSKNFTEQIILGNILEELIDNKTDIDVETKLNLGGTQVSFNALKTGGIDMYVEYTGTA
YGNMLNIKKPNRDRQAVYNTVKKEFKEKFGIEVLNPIGFNNTYVMATTKEIAQKYNLKTTSDLANVSSKMILGPTIEFAN
REDGIIGLNKAYNMNFKAVKPIDGGLRYKALVNNETQIIDAFTTDGLIEQFNLVLLEDDKHFFPDYYAVPIVKEETLKKF
PELKEVLGALDGKITDEKMRKLNYEVDVNKRDPKEVAKEFLQKEGLID
>Mature_528_residues
MMNNFIQQLILKRSEIFSLLIEHIELTLIAVLIAVVIGVPLGIIITKNKKIANIVIGFANLTQAIPSLAILGFLIPLIGI
GSAPAITMVVLYSMLPILKNTYTGITNINPDMLEAAKGLGMTNTQTLKLIKIPLAMPIIMAGVRIASVTAVGLMTIAAFV
GAGGLGYLVFSGIQTVDNNLILFGAIPAAILALIIDWITGRIEEATMPNGIKKADGTMKVKGNSSNKNRKRNTIIASILG
VLIVLALIVPKLIGLGDKKVVIGSKNFTEQIILGNILEELIDNKTDIDVETKLNLGGTQVSFNALKTGGIDMYVEYTGTA
YGNMLNIKKPNRDRQAVYNTVKKEFKEKFGIEVLNPIGFNNTYVMATTKEIAQKYNLKTTSDLANVSSKMILGPTIEFAN
REDGIIGLNKAYNMNFKAVKPIDGGLRYKALVNNETQIIDAFTTDGLIEQFNLVLLEDDKHFFPDYYAVPIVKEETLKKF
PELKEVLGALDGKITDEKMRKLNYEVDVNKRDPKEVAKEFLQKEGLID

Specific function: Involved in a high affinity multicomponent binding- protein-dependent transport system for glycine betaine, carnitine and choline; probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG1732

COG function: function code M; Periplasmic glycine betaine/choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1788451, Length=201, Percent_Identity=36.318407960199, Blast_Score=127, Evalue=2e-30,
Organism=Escherichia coli, GI1788449, Length=198, Percent_Identity=33.8383838383838, Blast_Score=109, Evalue=5e-25,
Organism=Escherichia coli, GI1788452, Length=301, Percent_Identity=27.5747508305648, Blast_Score=104, Evalue=2e-23,
Organism=Escherichia coli, GI1789033, Length=180, Percent_Identity=32.2222222222222, Blast_Score=103, Evalue=2e-23,
Organism=Escherichia coli, GI1786564, Length=170, Percent_Identity=27.0588235294118, Blast_Score=63, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 57789; Mature: 57789

Theoretical pI: Translated: 9.50; Mature: 9.50

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMNNFIQQLILKRSEIFSLLIEHIELTLIAVLIAVVIGVPLGIIITKNKKIANIVIGFAN
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCEEEHHEEEHHH
LTQAIPSLAILGFLIPLIGIGSAPAITMVVLYSMLPILKNTYTGITNINPDMLEAAKGLG
HHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHCCC
MTNTQTLKLIKIPLAMPIIMAGVRIASVTAVGLMTIAAFVGAGGLGYLVFSGIQTVDNNL
CCCCCEEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCE
ILFGAIPAAILALIIDWITGRIEEATMPNGIKKADGTMKVKGNSSNKNRKRNTIIASILG
EEEECHHHHHHHHHHHHHHCCCHHCCCCCCCCCCCCEEEEECCCCCCCHHHHHHHHHHHH
VLIVLALIVPKLIGLGDKKVVIGSKNFTEQIILGNILEELIDNKTDIDVETKLNLGGTQV
HHHHHHHHHHHHHCCCCCEEEECCCCCHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCEE
SFNALKTGGIDMYVEYTGTAYGNMLNIKKPNRDRQAVYNTVKKEFKEKFGIEVLNPIGFN
EEEEEECCCEEEEEEEECCCCCCEEECCCCCCHHHHHHHHHHHHHHHHCCCEEECCCCCC
NTYVMATTKEIAQKYNLKTTSDLANVSSKMILGPTIEFANREDGIIGLNKAYNMNFKAVK
CEEEEEEHHHHHHHCCCCCHHHHHHCCCCEEECCCEEECCCCCCEEECCCCCCCCCEEEC
PIDGGLRYKALVNNETQIIDAFTTDGLIEQFNLVLLEDDKHFFPDYYAVPIVKEETLKKF
CCCCCCEEEEEECCCCEEEEEHHCCCHHHHCCEEEEECCCCCCCCEEEECEECHHHHHHC
PELKEVLGALDGKITDEKMRKLNYEVDVNKRDPKEVAKEFLQKEGLID
HHHHHHHHHHCCCCCHHHHHHCCCEEECCCCCHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MMNNFIQQLILKRSEIFSLLIEHIELTLIAVLIAVVIGVPLGIIITKNKKIANIVIGFAN
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCEEEHHEEEHHH
LTQAIPSLAILGFLIPLIGIGSAPAITMVVLYSMLPILKNTYTGITNINPDMLEAAKGLG
HHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHCCC
MTNTQTLKLIKIPLAMPIIMAGVRIASVTAVGLMTIAAFVGAGGLGYLVFSGIQTVDNNL
CCCCCEEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCE
ILFGAIPAAILALIIDWITGRIEEATMPNGIKKADGTMKVKGNSSNKNRKRNTIIASILG
EEEECHHHHHHHHHHHHHHCCCHHCCCCCCCCCCCCEEEEECCCCCCCHHHHHHHHHHHH
VLIVLALIVPKLIGLGDKKVVIGSKNFTEQIILGNILEELIDNKTDIDVETKLNLGGTQV
HHHHHHHHHHHHHCCCCCEEEECCCCCHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCEE
SFNALKTGGIDMYVEYTGTAYGNMLNIKKPNRDRQAVYNTVKKEFKEKFGIEVLNPIGFN
EEEEEECCCEEEEEEEECCCCCCEEECCCCCCHHHHHHHHHHHHHHHHCCCEEECCCCCC
NTYVMATTKEIAQKYNLKTTSDLANVSSKMILGPTIEFANREDGIIGLNKAYNMNFKAVK
CEEEEEEHHHHHHHCCCCCHHHHHHCCCCEEECCCEEECCCCCCEEECCCCCCCCCEEEC
PIDGGLRYKALVNNETQIIDAFTTDGLIEQFNLVLLEDDKHFFPDYYAVPIVKEETLKKF
CCCCCCEEEEEECCCCEEEEEHHCCCHHHHCCEEEEECCCCCCCCEEEECEECHHHHHHC
PELKEVLGALDGKITDEKMRKLNYEVDVNKRDPKEVAKEFLQKEGLID
HHHHHHHHHHCCCCCHHHHHHCCCEEECCCCCHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10216873; 9384377 [H]