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The map label for this gene is acoR [H]

Identifier: 148379589

GI number: 148379589

Start: 1765651

End: 1767603

Strand: Direct

Name: acoR [H]

Synonym: CBO1628

Alternate gene names: 148379589

Gene position: 1765651-1767603 (Clockwise)

Preceding gene: 148379588

Following gene: 148379590

Centisome position: 45.43

GC content: 28.47

Gene sequence:

>1953_bases
ATGATTAATATATTAGAGGTAGAAAAACAAAGGGAAAATTTCATTAAAAATAATGATATACCGAAAAGTGTAAGACCTGA
GATATTAAATTCATGGATAAGATGTAAAAACTATAATGTAGATACTAATAATGGACAAGGTAAAGAATTACCTAAAGAGG
AATTTGAAAAAATACTATATGAAAAAAGAGATCTTATTCAAATAGCTATACCTGCTATGATTGATTTATACAATGTAGTA
AAGGATACAAACTATTCCATTATTTTAGCGGATGAAAATGCAGTAATTCTTGAAGTTATAGGAAACGAAGAAATAATGAA
TAAAAATATGGAATTGCATTTTCTTAAAGGATGCAAATGGATGGAAAAGGATGTAGGTACTAATGCCATAGGAACTAGTA
TTTATTTAGACAAGCCAATACAGACAATAGGAGCGGAACATTATTGTAAAAGGCAACATGGATGGACTTGTTCTGCGGCG
CCTATACATGATGAAAAAGGAAAAATTATAGGTGTTATAGACTTATCTGGAGATTTTTATGATTATCAAATTCATACCCT
TGGGATAGTAGTTGAGGCAGCAAAAACTATAGAAAAGCAATTTGCCATAGTTCAGCACAGAAAGTGGGTAGAGGTTGCGT
TTAGCTCTATTGAGGATGGTATTTTGGTTATAGACAAAGATTTTTCTGTTAAAGATTTCAATAAAAAACTATGTGAAATT
CTACAGGTGTCAGAGGATAAGGTTGGCAGATTAGATATAAAATTACTTTTAAAAGATATCATAAAGGATGAAAATAACTT
TAGTGATAATAGAATTAACTATAAAGAGGCTAATTTATATTTAGAAAATCGTAAATTAGAGTGCAATATAAATGTTTCTC
CCGTAAAACTAGAAAGTAAATATATTGGATATGTTATACTGGTTAAAAAAATTGATAGCATTAGAAATGTGGTTAGAAAA
ATAGCGGGCTTTTCATCTAAATATACCTTTGAAAGCATAATAACTAATAATGAAAGAATGTTATCCGTAATTGAGGAGGC
TAAAAAAATTGCTGAAAATGAATGCTCAGTGTTAATTAGTGGGGAAAGCGGCACCGGTAAAGAATTGTTTGCTCATTCAA
TTCATAACTCTAGTAATCGATGTAAAGGTCCCTTTATAGCAATAAACTGTGCAGCCCTCCCAAAAGATTTAGTTGAAAGT
GAATTTTTTGGATACGAAAAATCTGCTTTTACAGGGGCATCAAAGGATGGAAATCCTGGAAAGTTTGAATTGGCAAATAA
AGGTACAATTTTTTTAGATGAAATTGGAGAATTGCCCTTAGAAATCCAATCTAAGCTTTTAAGAGTTTTAGATAATCATA
CAATAACAAGAATAGGTGGAAATTATGAAAGAAAATTAGATGTAAGAGTTATAGCTGCAACAAATAGGAATTTAAATGAA
GAAATTAATAAAAATAATTTTAGAAGTGATTTATATTATAGATTAAATGTATTTAATGTAAGATTAATTCCTTTAAGGGA
AAGACCAGAAGATGTTGAATTGTGTGCAGATTATTTCCTTCAAAGATTAAATGATAAAAACCAAAGAATGGATAAATCTT
TTGATAAAGATTTTATAAATTTAATTAAAGACTACAATTGGCCAGGAAATGTGAGAGAGCTCGAAAATGTAATTCAAAGA
GCATATTATTTATCTAAGGATGAAATTATTAATTATTCTTTTATTCCAGAGTATATAAATGGAAATATAAAAGAAGAGGA
AATTAAAAATAAGAAAGAAAAATCTAAACCACTAACCCTTGAAGAAATGGAAAAGAAGCTAATTATACAAGCTTTAAAGT
ATTGTAATGGTAATGTTGTTAATGCTAGTAAGATTATAGGAATAGGTAAATCAACTTTATATAGAAAAATAGAAAAGTAT
AGATTAGAGGAGGTTTCAAAATGGGAAAAATAA

Upstream 100 bases:

>100_bases
TTTAAGTATTAATTTAAAAAAGAAAAGAATATTTATGTTGATAAATTTAAATTGTTTTAATAAATTTTTGCAAGAATTAT
TTATTATGTAGGTGATAACT

Downstream 100 bases:

>100_bases
TTAATAATTCCCATTTTGAAATAAGTATTTTCCCAAAATGAAACTTTAAAAATAAATAATCTTTAGAAGCCTTGCAAATG
CAAGGCTTTTTCTTTTGGCA

Product: signal-transduction and transcriptional-control protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 650; Mature: 650

Protein sequence:

>650_residues
MINILEVEKQRENFIKNNDIPKSVRPEILNSWIRCKNYNVDTNNGQGKELPKEEFEKILYEKRDLIQIAIPAMIDLYNVV
KDTNYSIILADENAVILEVIGNEEIMNKNMELHFLKGCKWMEKDVGTNAIGTSIYLDKPIQTIGAEHYCKRQHGWTCSAA
PIHDEKGKIIGVIDLSGDFYDYQIHTLGIVVEAAKTIEKQFAIVQHRKWVEVAFSSIEDGILVIDKDFSVKDFNKKLCEI
LQVSEDKVGRLDIKLLLKDIIKDENNFSDNRINYKEANLYLENRKLECNINVSPVKLESKYIGYVILVKKIDSIRNVVRK
IAGFSSKYTFESIITNNERMLSVIEEAKKIAENECSVLISGESGTGKELFAHSIHNSSNRCKGPFIAINCAALPKDLVES
EFFGYEKSAFTGASKDGNPGKFELANKGTIFLDEIGELPLEIQSKLLRVLDNHTITRIGGNYERKLDVRVIAATNRNLNE
EINKNNFRSDLYYRLNVFNVRLIPLRERPEDVELCADYFLQRLNDKNQRMDKSFDKDFINLIKDYNWPGNVRELENVIQR
AYYLSKDEIINYSFIPEYINGNIKEEEIKNKKEKSKPLTLEEMEKKLIIQALKYCNGNVVNASKIIGIGKSTLYRKIEKY
RLEEVSKWEK

Sequences:

>Translated_650_residues
MINILEVEKQRENFIKNNDIPKSVRPEILNSWIRCKNYNVDTNNGQGKELPKEEFEKILYEKRDLIQIAIPAMIDLYNVV
KDTNYSIILADENAVILEVIGNEEIMNKNMELHFLKGCKWMEKDVGTNAIGTSIYLDKPIQTIGAEHYCKRQHGWTCSAA
PIHDEKGKIIGVIDLSGDFYDYQIHTLGIVVEAAKTIEKQFAIVQHRKWVEVAFSSIEDGILVIDKDFSVKDFNKKLCEI
LQVSEDKVGRLDIKLLLKDIIKDENNFSDNRINYKEANLYLENRKLECNINVSPVKLESKYIGYVILVKKIDSIRNVVRK
IAGFSSKYTFESIITNNERMLSVIEEAKKIAENECSVLISGESGTGKELFAHSIHNSSNRCKGPFIAINCAALPKDLVES
EFFGYEKSAFTGASKDGNPGKFELANKGTIFLDEIGELPLEIQSKLLRVLDNHTITRIGGNYERKLDVRVIAATNRNLNE
EINKNNFRSDLYYRLNVFNVRLIPLRERPEDVELCADYFLQRLNDKNQRMDKSFDKDFINLIKDYNWPGNVRELENVIQR
AYYLSKDEIINYSFIPEYINGNIKEEEIKNKKEKSKPLTLEEMEKKLIIQALKYCNGNVVNASKIIGIGKSTLYRKIEKY
RLEEVSKWEK
>Mature_650_residues
MINILEVEKQRENFIKNNDIPKSVRPEILNSWIRCKNYNVDTNNGQGKELPKEEFEKILYEKRDLIQIAIPAMIDLYNVV
KDTNYSIILADENAVILEVIGNEEIMNKNMELHFLKGCKWMEKDVGTNAIGTSIYLDKPIQTIGAEHYCKRQHGWTCSAA
PIHDEKGKIIGVIDLSGDFYDYQIHTLGIVVEAAKTIEKQFAIVQHRKWVEVAFSSIEDGILVIDKDFSVKDFNKKLCEI
LQVSEDKVGRLDIKLLLKDIIKDENNFSDNRINYKEANLYLENRKLECNINVSPVKLESKYIGYVILVKKIDSIRNVVRK
IAGFSSKYTFESIITNNERMLSVIEEAKKIAENECSVLISGESGTGKELFAHSIHNSSNRCKGPFIAINCAALPKDLVES
EFFGYEKSAFTGASKDGNPGKFELANKGTIFLDEIGELPLEIQSKLLRVLDNHTITRIGGNYERKLDVRVIAATNRNLNE
EINKNNFRSDLYYRLNVFNVRLIPLRERPEDVELCADYFLQRLNDKNQRMDKSFDKDFINLIKDYNWPGNVRELENVIQR
AYYLSKDEIINYSFIPEYINGNIKEEEIKNKKEKSKPLTLEEMEKKLIIQALKYCNGNVVNASKIIGIGKSTLYRKIEKY
RLEEVSKWEK

Specific function: Member Of The Two-Component Regulatory System Atos/Atoc Involved In The Transcriptional Regulation Of The Ato Genes For Acetoacetate Metabolism. Also An Inhibitor Of Polyamine Biosynthesis. [C]

COG id: COG3284

COG function: function code QK; Transcriptional activator of acetoin/glycerol metabolism

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 sigma-54 factor interaction domain [H]

Homologues:

Organism=Escherichia coli, GI1788550, Length=338, Percent_Identity=42.603550295858, Blast_Score=284, Evalue=1e-77,
Organism=Escherichia coli, GI1789233, Length=303, Percent_Identity=43.8943894389439, Blast_Score=255, Evalue=7e-69,
Organism=Escherichia coli, GI1789087, Length=314, Percent_Identity=43.312101910828, Blast_Score=251, Evalue=7e-68,
Organism=Escherichia coli, GI87082117, Length=317, Percent_Identity=41.0094637223975, Blast_Score=250, Evalue=2e-67,
Organism=Escherichia coli, GI1790437, Length=308, Percent_Identity=41.5584415584416, Blast_Score=249, Evalue=3e-67,
Organism=Escherichia coli, GI1788905, Length=349, Percent_Identity=35.5300859598854, Blast_Score=246, Evalue=4e-66,
Organism=Escherichia coli, GI1790299, Length=331, Percent_Identity=38.6706948640483, Blast_Score=240, Evalue=2e-64,
Organism=Escherichia coli, GI87081858, Length=647, Percent_Identity=25.5023183925811, Blast_Score=238, Evalue=1e-63,
Organism=Escherichia coli, GI1786524, Length=340, Percent_Identity=35.2941176470588, Blast_Score=224, Evalue=1e-59,
Organism=Escherichia coli, GI87082152, Length=314, Percent_Identity=40.4458598726115, Blast_Score=223, Evalue=2e-59,
Organism=Escherichia coli, GI1787583, Length=367, Percent_Identity=33.5149863760218, Blast_Score=214, Evalue=2e-56,
Organism=Escherichia coli, GI87081872, Length=314, Percent_Identity=37.5796178343949, Blast_Score=200, Evalue=2e-52,
Organism=Escherichia coli, GI1789828, Length=280, Percent_Identity=30.3571428571429, Blast_Score=134, Evalue=2e-32,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR020441
- InterPro:   IPR009057
- InterPro:   IPR002197
- InterPro:   IPR001610
- InterPro:   IPR000014
- InterPro:   IPR013767
- InterPro:   IPR002078 [H]

Pfam domain/function: PF02954 HTH_8; PF00989 PAS; PF00158 Sigma54_activat [H]

EC number: NA

Molecular weight: Translated: 74983; Mature: 74983

Theoretical pI: Translated: 6.79; Mature: 6.79

Prosite motif: PS00675 SIGMA54_INTERACT_1 ; PS00676 SIGMA54_INTERACT_2 ; PS00688 SIGMA54_INTERACT_3 ; PS50045 SIGMA54_INTERACT_4

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MINILEVEKQRENFIKNNDIPKSVRPEILNSWIRCKNYNVDTNNGQGKELPKEEFEKILY
CCCHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHH
EKRDLIQIAIPAMIDLYNVVKDTNYSIILADENAVILEVIGNEEIMNKNMELHFLKGCKW
HHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCEEEEEEECCHHHHCCCCEEEEECCCCH
MEKDVGTNAIGTSIYLDKPIQTIGAEHYCKRQHGWTCSAAPIHDEKGKIIGVIDLSGDFY
HHHHCCCCCCCCEEEECCCHHHHCHHHHHHHCCCCEECCCCCCCCCCCEEEEEECCCCEE
DYQIHTLGIVVEAAKTIEKQFAIVQHRKWVEVAFSSIEDGILVIDKDFSVKDFNKKLCEI
EEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHH
LQVSEDKVGRLDIKLLLKDIIKDENNFSDNRINYKEANLYLENRKLECNINVSPVKLESK
HHCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCEEEEEEEEECCEEEEEECCCEEEECCC
YIGYVILVKKIDSIRNVVRKIAGFSSKYTFESIITNNERMLSVIEEAKKIAENECSVLIS
CCEEEEEHHHHHHHHHHHHHHHCCCCCCCHHHHHCCCHHHHHHHHHHHHHCCCCCEEEEE
GESGTGKELFAHSIHNSSNRCKGPFIAINCAALPKDLVESEFFGYEKSAFTGASKDGNPG
CCCCCCHHHHHHHHCCCCCCCCCCEEEEEECCCCHHHHHHHHCCCCCHHCCCCCCCCCCC
KFELANKGTIFLDEIGELPLEIQSKLLRVLDNHTITRIGGNYERKLDVRVIAATNRNLNE
EEEECCCCEEEEECCCCCCHHHHHHHHHHHCCCEEEEECCCCCEEEEEEEEEECCCCCHH
EINKNNFRSDLYYRLNVFNVRLIPLRERPEDVELCADYFLQRLNDKNQRMDKSFDKDFIN
HHCCCCCCCCEEEEEEEEEEEEEECCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHH
LIKDYNWPGNVRELENVIQRAYYLSKDEIINYSFIPEYINGNIKEEEIKNKKEKSKPLTL
HHHCCCCCCCHHHHHHHHHHHHHCCHHHEEEEEECHHHHCCCCCHHHHHHHHHHCCCCCH
EEMEKKLIIQALKYCNGNVVNASKIIGIGKSTLYRKIEKYRLEEVSKWEK
HHHHHHHHHHHHHHCCCCEEEHHHEEECCHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MINILEVEKQRENFIKNNDIPKSVRPEILNSWIRCKNYNVDTNNGQGKELPKEEFEKILY
CCCHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHH
EKRDLIQIAIPAMIDLYNVVKDTNYSIILADENAVILEVIGNEEIMNKNMELHFLKGCKW
HHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCEEEEEEECCHHHHCCCCEEEEECCCCH
MEKDVGTNAIGTSIYLDKPIQTIGAEHYCKRQHGWTCSAAPIHDEKGKIIGVIDLSGDFY
HHHHCCCCCCCCEEEECCCHHHHCHHHHHHHCCCCEECCCCCCCCCCCEEEEEECCCCEE
DYQIHTLGIVVEAAKTIEKQFAIVQHRKWVEVAFSSIEDGILVIDKDFSVKDFNKKLCEI
EEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHH
LQVSEDKVGRLDIKLLLKDIIKDENNFSDNRINYKEANLYLENRKLECNINVSPVKLESK
HHCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCEEEEEEEEECCEEEEEECCCEEEECCC
YIGYVILVKKIDSIRNVVRKIAGFSSKYTFESIITNNERMLSVIEEAKKIAENECSVLIS
CCEEEEEHHHHHHHHHHHHHHHCCCCCCCHHHHHCCCHHHHHHHHHHHHHCCCCCEEEEE
GESGTGKELFAHSIHNSSNRCKGPFIAINCAALPKDLVESEFFGYEKSAFTGASKDGNPG
CCCCCCHHHHHHHHCCCCCCCCCCEEEEEECCCCHHHHHHHHCCCCCHHCCCCCCCCCCC
KFELANKGTIFLDEIGELPLEIQSKLLRVLDNHTITRIGGNYERKLDVRVIAATNRNLNE
EEEECCCCEEEEECCCCCCHHHHHHHHHHHCCCEEEEECCCCCEEEEEEEEEECCCCCHH
EINKNNFRSDLYYRLNVFNVRLIPLRERPEDVELCADYFLQRLNDKNQRMDKSFDKDFIN
HHCCCCCCCCEEEEEEEEEEEEEECCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHH
LIKDYNWPGNVRELENVIQRAYYLSKDEIINYSFIPEYINGNIKEEEIKNKKEKSKPLTL
HHHCCCCCCCHHHHHHHHHHHHHCCHHHEEEEEECHHHHCCCCCHHHHHHHHHHCCCCCH
EEMEKKLIIQALKYCNGNVVNASKIIGIGKSTLYRKIEKYRLEEVSKWEK
HHHHHHHHHHHHHHCCCCEEEHHHEEECCHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA