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The map label for this gene is fnr [H]

Identifier: 148378948

GI number: 148378948

Start: 1055400

End: 1056107

Strand: Direct

Name: fnr [H]

Synonym: CBO0955

Alternate gene names: 148378948

Gene position: 1055400-1056107 (Clockwise)

Preceding gene: 148378947

Following gene: 148378949

Centisome position: 27.15

GC content: 25.56

Gene sequence:

>708_bases
ATGGGGGTATTAATTCTCATGAACAGTTCAATAAAATATAAATTAAAGGATTTAGAGATATTTTCTAGTCTTAAAAATGA
TGAATTAGATATGTTAGCTAATAAATCTAGAGTAATAGATTTAAAAAAAGGAGAAATCTTATTTTATGAAAGAGATTCTG
TAGATAATGTATATATAGTATTAGAAGGAAAAGTTACTTTGTATAGAATTTCAGAAAATGGACAAAAAAGAGTAGTATTT
ATAATAGATAAGGGGAAATTTATAAATGAAATTATACTAGATAAGAAGCCAGCGTCTATATGCTGTGAGGGATTTGAAAA
CAGTAAAGTTTTATCAATTAAAAGAAATGATTTATTATATATAATGGGTGGAAATTTTGAATTTACCCAAGAAGTGATGT
TTTCAATGACTAATAAAATAAGAAGGATGTATAGACAATTAAAAAATACAGTACCTCTTAAAGTAGAAAAAAGAGTAGCG
GCTAAGCTTTGGAAATTGGCTAAAGATTATGGTGAGTATGGAAAAAATGGAGAAGTCATAAAGCTAAATATAACAGTTAC
TTATCTCTCAGAAATGTTAGGAAGTTCAAGGGAAACTATATCTAGAGCACTGAAAGAGTTAAAAAATAAAGAACTTATAT
ATTATGAAGGTAAAAAAATAATAATTAAAGATAGAGATAAATTATCAAAGTTTTTTAAGGGTATGTGA

Upstream 100 bases:

>100_bases
AATAATAAGCAGAGAAGTAATTTGTTTTAATGTGCAGGAATAGGAATACCAAGGTTCGCTTATAATTGAAAGCTTGCAAA
ACAATAAGAGAATTATATAA

Downstream 100 bases:

>100_bases
TTTTCATCACATACTTTTTTTTGTATGCACTATAGAATAGAGTATAAGAAATAATGGAGTTATTAAAAAAAGAAAGGAGA
TGTTGGATCATGTATAGTGA

Product: CRP family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 235; Mature: 234

Protein sequence:

>235_residues
MGVLILMNSSIKYKLKDLEIFSSLKNDELDMLANKSRVIDLKKGEILFYERDSVDNVYIVLEGKVTLYRISENGQKRVVF
IIDKGKFINEIILDKKPASICCEGFENSKVLSIKRNDLLYIMGGNFEFTQEVMFSMTNKIRRMYRQLKNTVPLKVEKRVA
AKLWKLAKDYGEYGKNGEVIKLNITVTYLSEMLGSSRETISRALKELKNKELIYYEGKKIIIKDRDKLSKFFKGM

Sequences:

>Translated_235_residues
MGVLILMNSSIKYKLKDLEIFSSLKNDELDMLANKSRVIDLKKGEILFYERDSVDNVYIVLEGKVTLYRISENGQKRVVF
IIDKGKFINEIILDKKPASICCEGFENSKVLSIKRNDLLYIMGGNFEFTQEVMFSMTNKIRRMYRQLKNTVPLKVEKRVA
AKLWKLAKDYGEYGKNGEVIKLNITVTYLSEMLGSSRETISRALKELKNKELIYYEGKKIIIKDRDKLSKFFKGM
>Mature_234_residues
GVLILMNSSIKYKLKDLEIFSSLKNDELDMLANKSRVIDLKKGEILFYERDSVDNVYIVLEGKVTLYRISENGQKRVVFI
IDKGKFINEIILDKKPASICCEGFENSKVLSIKRNDLLYIMGGNFEFTQEVMFSMTNKIRRMYRQLKNTVPLKVEKRVAA
KLWKLAKDYGEYGKNGEVIKLNITVTYLSEMLGSSRETISRALKELKNKELIYYEGKKIIIKDRDKLSKFFKGM

Specific function: It is involved in the activation of genes necessary for anaerobic respiration [H]

COG id: COG0664

COG function: function code T; cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH crp-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1787595, Length=232, Percent_Identity=25, Blast_Score=64, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018490
- InterPro:   IPR000595
- InterPro:   IPR001808
- InterPro:   IPR012318
- InterPro:   IPR014710
- InterPro:   IPR018335
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00027 cNMP_binding; PF00325 Crp [H]

EC number: NA

Molecular weight: Translated: 27331; Mature: 27199

Theoretical pI: Translated: 10.10; Mature: 10.10

Prosite motif: PS50042 CNMP_BINDING_3 ; PS51063 HTH_CRP_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGVLILMNSSIKYKLKDLEIFSSLKNDELDMLANKSRVIDLKKGEILFYERDSVDNVYIV
CEEEEEECCCCEEEEHHHHHHHHCCCCCHHHHCCCCEEEEEECCEEEEEECCCCCEEEEE
LEGKVTLYRISENGQKRVVFIIDKGKFINEIILDKKPASICCEGFENSKVLSIKRNDLLY
EECCEEEEEECCCCCEEEEEEEECCCHHHHHHCCCCCHHHHHCCCCCCEEEEEECCCEEE
IMGGNFEFTQEVMFSMTNKIRRMYRQLKNTVPLKVEKRVAAKLWKLAKDYGEYGKNGEVI
EECCCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHHHHCCCCCEE
KLNITVTYLSEMLGSSRETISRALKELKNKELIYYEGKKIIIKDRDKLSKFFKGM
EEEEEHHHHHHHHCCCHHHHHHHHHHHCCCEEEEECCCEEEEECHHHHHHHHCCC
>Mature Secondary Structure 
GVLILMNSSIKYKLKDLEIFSSLKNDELDMLANKSRVIDLKKGEILFYERDSVDNVYIV
EEEEEECCCCEEEEHHHHHHHHCCCCCHHHHCCCCEEEEEECCEEEEEECCCCCEEEEE
LEGKVTLYRISENGQKRVVFIIDKGKFINEIILDKKPASICCEGFENSKVLSIKRNDLLY
EECCEEEEEECCCCCEEEEEEEECCCHHHHHHCCCCCHHHHHCCCCCCEEEEEECCCEEE
IMGGNFEFTQEVMFSMTNKIRRMYRQLKNTVPLKVEKRVAAKLWKLAKDYGEYGKNGEVI
EECCCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHHHHCCCCCEE
KLNITVTYLSEMLGSSRETISRALKELKNKELIYYEGKKIIIKDRDKLSKFFKGM
EEEEEHHHHHHHHCCCHHHHHHHHHHHCCCEEEEECCCEEEEECHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: Fe [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11248100 [H]