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The map label for this gene is mrdB [H]

Identifier: 148378616

GI number: 148378616

Start: 714300

End: 715460

Strand: Direct

Name: mrdB [H]

Synonym: CBO0615

Alternate gene names: 148378616

Gene position: 714300-715460 (Clockwise)

Preceding gene: 148378612

Following gene: 148378618

Centisome position: 18.38

GC content: 28.94

Gene sequence:

>1161_bases
TTGATTAGAAGAAAGAATGTCAATTTAAATAAATCTTTTAATTTAAAAAGGCACATAAAATATTTTGATGTTTTTTTGTT
TATTGTGATAATTCTCATATCAATTTTAGGGATTGTTATGATTAGCAGCGCAACATCTAATTTTGAAAATAGTAGAAAGT
ATATTATTACTCAAATTTTATCCCTTGTAATTGGATTGGTTTTCATGTTTATAACAATTTATATAGATTACCGAAATATT
GGACGTGCCTATAAGATTATTTATATATTTAATTTTCTATTACTGGCAGGTGTAATTCTTCTTGGTACGGGTAAAGACCA
ATGGGGGGCACAAAGGTGGATACGAATAGGGGGGATAGGAATACAACCATCAGAAATTGCAAAAATAGGATTTATTATTA
CTTTTGCAAAATTTCTGGAATTAATAAAAGACGATTTAAATAAAATAAAATATTTATTGGCGGCCTTTTGTTATATTGGA
GTGCCTATTATACTTGTAATGATCCAACCGGATTTAGGAACTGCTCTATCCTTTGTTTTTATTTCTATTGCAATGATATA
TATTTGTGGTATAGATTATAAATATATTTTAGGGGGATTTTTAGCCTGCATTGTTATTATACCTATTGCTTGGCAATATG
TGCTTAAAGCATATCAAAAGAATAGAATTTTAATTTTTATTAATCCTGATTCAGATCCTATGGGAGGAGGATACCATGTT
CTTCAGTCTAAAATAGCAGTAGGTTCTGGCGAATTTTTTGGTACAGGATTATTTAAGGGTTCTCATGCACAAAATTTTCT
GCCTGAAAAGCATACAGACTTTATATTTGCTCTTATTGGGGAAGAATTGGGTTTTATAGGAAGTATAATTGTGGTATTAC
TTCTTTTAATAATAGTCTTAAGATGTATTTCAATAGCCAAATCTGCTAAAGACAATTTGGGATGTTATATTTGTGTTGGA
GTTGCTAGTATGATCATATTCCAGACTTTTATAAATATTGGAATGTGTATTGGTATTATGCCTGTTACAGGTATTCCTTT
ACCATTTATTAGTTATGGAGGTTCATCTCTTATTACTAATTTTGTAGCAATGGGATTAGTTTTAAATGTAGGATTAAGGC
ATAAACCTATTAATTTTTTCAAAGGTAGCATAAATAATTAA

Upstream 100 bases:

>100_bases
ATTGGATACCAATGTAGATAGCTTAGTATTGTAAATTAATGAAAAATTTAGCGCTGTTAAATTTAGGTGATTTAATAAAG
TGTAGAAAGCTGGTGTACTA

Downstream 100 bases:

>100_bases
CTATATAATAAGAGGGTGTCTCAAAATAAAAACAGCATTAATTTTAAAACCGTAAATATAAATAATACATTCATAAAGCA
ATTCATTTTACTAAGTAGTT

Product: rod shape-determining protein RodA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 386; Mature: 386

Protein sequence:

>386_residues
MIRRKNVNLNKSFNLKRHIKYFDVFLFIVIILISILGIVMISSATSNFENSRKYIITQILSLVIGLVFMFITIYIDYRNI
GRAYKIIYIFNFLLLAGVILLGTGKDQWGAQRWIRIGGIGIQPSEIAKIGFIITFAKFLELIKDDLNKIKYLLAAFCYIG
VPIILVMIQPDLGTALSFVFISIAMIYICGIDYKYILGGFLACIVIIPIAWQYVLKAYQKNRILIFINPDSDPMGGGYHV
LQSKIAVGSGEFFGTGLFKGSHAQNFLPEKHTDFIFALIGEELGFIGSIIVVLLLLIIVLRCISIAKSAKDNLGCYICVG
VASMIIFQTFINIGMCIGIMPVTGIPLPFISYGGSSLITNFVAMGLVLNVGLRHKPINFFKGSINN

Sequences:

>Translated_386_residues
MIRRKNVNLNKSFNLKRHIKYFDVFLFIVIILISILGIVMISSATSNFENSRKYIITQILSLVIGLVFMFITIYIDYRNI
GRAYKIIYIFNFLLLAGVILLGTGKDQWGAQRWIRIGGIGIQPSEIAKIGFIITFAKFLELIKDDLNKIKYLLAAFCYIG
VPIILVMIQPDLGTALSFVFISIAMIYICGIDYKYILGGFLACIVIIPIAWQYVLKAYQKNRILIFINPDSDPMGGGYHV
LQSKIAVGSGEFFGTGLFKGSHAQNFLPEKHTDFIFALIGEELGFIGSIIVVLLLLIIVLRCISIAKSAKDNLGCYICVG
VASMIIFQTFINIGMCIGIMPVTGIPLPFISYGGSSLITNFVAMGLVLNVGLRHKPINFFKGSINN
>Mature_386_residues
MIRRKNVNLNKSFNLKRHIKYFDVFLFIVIILISILGIVMISSATSNFENSRKYIITQILSLVIGLVFMFITIYIDYRNI
GRAYKIIYIFNFLLLAGVILLGTGKDQWGAQRWIRIGGIGIQPSEIAKIGFIITFAKFLELIKDDLNKIKYLLAAFCYIG
VPIILVMIQPDLGTALSFVFISIAMIYICGIDYKYILGGFLACIVIIPIAWQYVLKAYQKNRILIFINPDSDPMGGGYHV
LQSKIAVGSGEFFGTGLFKGSHAQNFLPEKHTDFIFALIGEELGFIGSIIVVLLLLIIVLRCISIAKSAKDNLGCYICVG
VASMIIFQTFINIGMCIGIMPVTGIPLPFISYGGSSLITNFVAMGLVLNVGLRHKPINFFKGSINN

Specific function: This is one of the proteins responsible for the rod shape of the cell. It is required for the expression of the enzymatic activity of PBP2, which is thought to synthesize peptidoglycan in the step of initiation of cell elongation [H]

COG id: COG0772

COG function: function code D; Bacterial cell division membrane protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ftsW/rodA/spoVE family [H]

Homologues:

Organism=Escherichia coli, GI1786853, Length=321, Percent_Identity=37.0716510903427, Blast_Score=199, Evalue=2e-52,
Organism=Escherichia coli, GI1786277, Length=377, Percent_Identity=29.4429708222812, Blast_Score=170, Evalue=1e-43,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001182
- InterPro:   IPR018365
- InterPro:   IPR011923 [H]

Pfam domain/function: PF01098 FTSW_RODA_SPOVE [H]

EC number: NA

Molecular weight: Translated: 42950; Mature: 42950

Theoretical pI: Translated: 9.80; Mature: 9.80

Prosite motif: PS00428 FTSW_RODA_SPOVE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIRRKNVNLNKSFNLKRHIKYFDVFLFIVIILISILGIVMISSATSNFENSRKYIITQIL
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHH
SLVIGLVFMFITIYIDYRNIGRAYKIIYIFNFLLLAGVILLGTGKDQWGAQRWIRIGGIG
HHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHEEECCCC
IQPSEIAKIGFIITFAKFLELIKDDLNKIKYLLAAFCYIGVPIILVMIQPDLGTALSFVF
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCHHHHHHHHH
ISIAMIYICGIDYKYILGGFLACIVIIPIAWQYVLKAYQKNRILIFINPDSDPMGGGYHV
HHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCHHH
LQSKIAVGSGEFFGTGLFKGSHAQNFLPEKHTDFIFALIGEELGFIGSIIVVLLLLIIVL
HHHHHHCCCCCCEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RCISIAKSAKDNLGCYICVGVASMIIFQTFINIGMCIGIMPVTGIPLPFISYGGSSLITN
HHHHHHHHCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHCCCHHHHHH
FVAMGLVLNVGLRHKPINFFKGSINN
HHHHHHHHHCCCCCCCCHHHCCCCCC
>Mature Secondary Structure
MIRRKNVNLNKSFNLKRHIKYFDVFLFIVIILISILGIVMISSATSNFENSRKYIITQIL
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHH
SLVIGLVFMFITIYIDYRNIGRAYKIIYIFNFLLLAGVILLGTGKDQWGAQRWIRIGGIG
HHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHEEECCCC
IQPSEIAKIGFIITFAKFLELIKDDLNKIKYLLAAFCYIGVPIILVMIQPDLGTALSFVF
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCHHHHHHHHH
ISIAMIYICGIDYKYILGGFLACIVIIPIAWQYVLKAYQKNRILIFINPDSDPMGGGYHV
HHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCHHH
LQSKIAVGSGEFFGTGLFKGSHAQNFLPEKHTDFIFALIGEELGFIGSIIVVLLLLIIVL
HHHHHHCCCCCCEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RCISIAKSAKDNLGCYICVGVASMIIFQTFINIGMCIGIMPVTGIPLPFISYGGSSLITN
HHHHHHHHCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHCCCHHHHHH
FVAMGLVLNVGLRHKPINFFKGSINN
HHHHHHHHHCCCCCCCCHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]