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The map label for this gene is perR [H]

Identifier: 148378398

GI number: 148378398

Start: 464643

End: 465059

Strand: Direct

Name: perR [H]

Synonym: CBO0395

Alternate gene names: 148378398

Gene position: 464643-465059 (Clockwise)

Preceding gene: 148378397

Following gene: 148378400

Centisome position: 11.95

GC content: 22.54

Gene sequence:

>417_bases
TTGAAGAAAAACAATTTAAAATTAACTAAAGGTAGAATAAATATTTTAAGTATACTTATAGAAGCAACTTATTCTTTAGA
TGTGGAGAGTATATTCAAAAAATTAAAAGAAAAAAATGTAAATTTAGACTTATCTACTATATATAGAACACTAGAAGTTT
TTGAAAATAAGGATTTAATAGAGAAATTTGATTTAGGAAATTCAAAATACAATTTTAGATTTAAAAGAAAAAAGCATACT
CACACTATACAGTGTAAAGTATGTCATAAAGAAGTGCAGATAGAATGTCCTTTGTTTCATCTTGATGAAATAGTAAACAA
AGAAACTGGATTTTCTAATATTGATCATCATTTAAAAATAGAAGGTGTATGTGAAAACTGTGTAAAATATAATTGTATAA
AAGAGAAAAAGCATTAA

Upstream 100 bases:

>100_bases
GAAAATGTTATTTTTTTAAAATTATTAATAGGTATTGAGTTATGTTTACTAATTATTGTATTATTATCATAAGGTGATAA
TTATGATAGAAGAGGAATTA

Downstream 100 bases:

>100_bases
GGCGCATCTGGAGTTTTTTCTTTTGAATAATTGTAATTCTCAGATGTTTTTTTTACTTTCCATGCTCCATTTTTGCTTTT
AGTAAGGAATAAATTGTAGG

Product: ferric uptake regulation protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 138; Mature: 138

Protein sequence:

>138_residues
MKKNNLKLTKGRINILSILIEATYSLDVESIFKKLKEKNVNLDLSTIYRTLEVFENKDLIEKFDLGNSKYNFRFKRKKHT
HTIQCKVCHKEVQIECPLFHLDEIVNKETGFSNIDHHLKIEGVCENCVKYNCIKEKKH

Sequences:

>Translated_138_residues
MKKNNLKLTKGRINILSILIEATYSLDVESIFKKLKEKNVNLDLSTIYRTLEVFENKDLIEKFDLGNSKYNFRFKRKKHT
HTIQCKVCHKEVQIECPLFHLDEIVNKETGFSNIDHHLKIEGVCENCVKYNCIKEKKH
>Mature_138_residues
MKKNNLKLTKGRINILSILIEATYSLDVESIFKKLKEKNVNLDLSTIYRTLEVFENKDLIEKFDLGNSKYNFRFKRKKHT
HTIQCKVCHKEVQIECPLFHLDEIVNKETGFSNIDHHLKIEGVCENCVKYNCIKEKKH

Specific function: Hydrogen and organic peroxide sensor. Represses the expression of a regulon of peroxide-inducible genes such as katA, ahpC, ahpF, the heme biosynthesis operon (hemAXCDBL), fur, perR, zosA and mrgA [H]

COG id: COG0735

COG function: function code P; Fe2+/Zn2+ uptake regulation proteins

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Fur family [H]

Homologues:

None

Paralogues:

None

Copy number: 3432 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002481
- InterPro:   IPR011991 [H]

Pfam domain/function: PF01475 FUR [H]

EC number: NA

Molecular weight: Translated: 16325; Mature: 16325

Theoretical pI: Translated: 9.25; Mature: 9.25

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

4.3 %Cys     (Translated Protein)
0.7 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
4.3 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKNNLKLTKGRINILSILIEATYSLDVESIFKKLKEKNVNLDLSTIYRTLEVFENKDLI
CCCCCEEEECCHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCHH
EKFDLGNSKYNFRFKRKKHTHTIQCKVCHKEVQIECPLFHLDEIVNKETGFSNIDHHLKI
HHHCCCCCEEEEEEECCCCCEEEEEEEECCEEEEECCHHHHHHHHCCCCCCCCCCCEEEE
EGVCENCVKYNCIKEKKH
HHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MKKNNLKLTKGRINILSILIEATYSLDVESIFKKLKEKNVNLDLSTIYRTLEVFENKDLI
CCCCCEEEECCHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCHH
EKFDLGNSKYNFRFKRKKHTHTIQCKVCHKEVQIECPLFHLDEIVNKETGFSNIDHHLKI
HHHCCCCCEEEEEEECCCCCEEEEEEEECCEEEEECCHHHHHHHHCCCCCCCCCCCEEEE
EGVCENCVKYNCIKEKKH
HHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9202460; 9384377; 9701813; 12100544 [H]