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The map label for this gene is ycgO [C]

Identifier: 148378364

GI number: 148378364

Start: 419173

End: 420447

Strand: Direct

Name: ycgO [C]

Synonym: CBO0361

Alternate gene names: 148378364

Gene position: 419173-420447 (Clockwise)

Preceding gene: 148378363

Following gene: 148378366

Centisome position: 10.78

GC content: 28.24

Gene sequence:

>1275_bases
TTGAAAATGGAAACAAATGTAATTTTATCAGCTAATAATATATTAAAGTTAATTGCATTAGTTATTTTAGCTGGTGTAGT
ATTTGGCAAAATAAGCAGAAAAGTCAATTTGCCAGATGTGGTCTTATTTATTTTAGCAGGGGTCATACTAGGGCCAGAAG
TATTGAATCTTATAAATATAGATTCTTACCCTGTGGGAAATCAGCTTATATTAACTTTTGGGGCAGCTTATATTCTTTAT
GATGGTGGTAGAGAAATTGATTTGAAAGTTTTTAATGAGGTAAAAATATCTGTGTTGCTTTTGTCAACCTTAGGGGTTTT
AATATCTACAGGTATTACAGGATTTTTTGTTTATAAAATATTTCATATAGATTTTATATATGCATTATTATTAGGTGCAA
TAATATCATCTACAGACCCATCAGTTTTAGTACCTTTGTTTAAAAATATGAATGTAAGTAATAAATTAAAACAAACCATA
ATATCTGAATCAGCATTTAATGATGCTGCTGCAGCAATAGTAACCTTTGCTATTTTAGGGGTTATAGCAGGTGGTGAGTT
TTCATTAGGCAAGAGTATTTTTGAATTATTAAAGTCATCTTTAGGAGGAATTTTAATAGGAGGTATATTTGGTTATATTT
CTACCAAATTAATAGCAGGAGAAAAGTATGCATTTTTAAAGGAATTTCCTTCAGAAGTATCAATAGTAGCAGTAATAGGG
ACTTATTTAATTGCAGATAAATTAGGTGTTAGTGGGTTTATGGCAGTATTCATAATAGGTATGGTATGTGGAAATAAGAA
AAGAATTAATTGCTGTATACCAGATGAATATAATCAAACTCATCTTAGATTTAAAGAGGTTTTAACTATAATATTAAGAA
TGATGATATTTGTTTTATTAGGAAGCCATATAGATTTTGGAGTATTATCTAAATATTTTACAAAGGATTTGATGGTAGTA
GCATTATTAATTTTTGTTTCAAGACCAGTGTCAGCATTTTTATCAGTTATATTTGATAGAAAAGCAAAATGGAATATAAA
AGAGATAATTTATCTTATGTGGGTTAGAGAAACAGGAGTTATACCAGCAGCTTTGGTGGGTATGTTATTAACAATGCATA
TAAAAAATTCAGATATAATAGCGTCAGTCACATTTATAACCATAATAATAACATTAACATTCCAAGCAAGTACCTCTAAA
TCGTTAGCTAAATTACTAAAATTAGATCTAGATGAAGGAAAGAAAGAAATAGCAGTAGATAGTATAAAGATATAA

Upstream 100 bases:

>100_bases
ATTGAAATAATTAACAAAAAAATTTGAAAAGTATATTGTAATTTAAATATAAAGGTGATATAACATATACAGTAACATAA
AAAATTGCTTGGAGATGATT

Downstream 100 bases:

>100_bases
AATATATAATAAATTATAAAGATGTACTAGTATAATTTATTTATAAATATAGGGTTTTAAAAATTTAAATTATAAAGGTA
TAAATTAACACCTATAAGTT

Product: transporter, monovalent cation:proton antiporter-2 (CPA2) family

Products: NA

Alternate protein names: MjNhaP2 [H]

Number of amino acids: Translated: 424; Mature: 424

Protein sequence:

>424_residues
MKMETNVILSANNILKLIALVILAGVVFGKISRKVNLPDVVLFILAGVILGPEVLNLINIDSYPVGNQLILTFGAAYILY
DGGREIDLKVFNEVKISVLLLSTLGVLISTGITGFFVYKIFHIDFIYALLLGAIISSTDPSVLVPLFKNMNVSNKLKQTI
ISESAFNDAAAAIVTFAILGVIAGGEFSLGKSIFELLKSSLGGILIGGIFGYISTKLIAGEKYAFLKEFPSEVSIVAVIG
TYLIADKLGVSGFMAVFIIGMVCGNKKRINCCIPDEYNQTHLRFKEVLTIILRMMIFVLLGSHIDFGVLSKYFTKDLMVV
ALLIFVSRPVSAFLSVIFDRKAKWNIKEIIYLMWVRETGVIPAALVGMLLTMHIKNSDIIASVTFITIIITLTFQASTSK
SLAKLLKLDLDEGKKEIAVDSIKI

Sequences:

>Translated_424_residues
MKMETNVILSANNILKLIALVILAGVVFGKISRKVNLPDVVLFILAGVILGPEVLNLINIDSYPVGNQLILTFGAAYILY
DGGREIDLKVFNEVKISVLLLSTLGVLISTGITGFFVYKIFHIDFIYALLLGAIISSTDPSVLVPLFKNMNVSNKLKQTI
ISESAFNDAAAAIVTFAILGVIAGGEFSLGKSIFELLKSSLGGILIGGIFGYISTKLIAGEKYAFLKEFPSEVSIVAVIG
TYLIADKLGVSGFMAVFIIGMVCGNKKRINCCIPDEYNQTHLRFKEVLTIILRMMIFVLLGSHIDFGVLSKYFTKDLMVV
ALLIFVSRPVSAFLSVIFDRKAKWNIKEIIYLMWVRETGVIPAALVGMLLTMHIKNSDIIASVTFITIIITLTFQASTSK
SLAKLLKLDLDEGKKEIAVDSIKI
>Mature_424_residues
MKMETNVILSANNILKLIALVILAGVVFGKISRKVNLPDVVLFILAGVILGPEVLNLINIDSYPVGNQLILTFGAAYILY
DGGREIDLKVFNEVKISVLLLSTLGVLISTGITGFFVYKIFHIDFIYALLLGAIISSTDPSVLVPLFKNMNVSNKLKQTI
ISESAFNDAAAAIVTFAILGVIAGGEFSLGKSIFELLKSSLGGILIGGIFGYISTKLIAGEKYAFLKEFPSEVSIVAVIG
TYLIADKLGVSGFMAVFIIGMVCGNKKRINCCIPDEYNQTHLRFKEVLTIILRMMIFVLLGSHIDFGVLSKYFTKDLMVV
ALLIFVSRPVSAFLSVIFDRKAKWNIKEIIYLMWVRETGVIPAALVGMLLTMHIKNSDIIASVTFITIIITLTFQASTSK
SLAKLLKLDLDEGKKEIAVDSIKI

Specific function: This is probably a Na(+)/H(+) antiporter [H]

COG id: COG3263

COG function: function code P; NhaP-type Na+/H+ and K+/H+ antiporters with a unique C-terminal domain

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family [H]

Homologues:

Organism=Homo sapiens, GI194239733, Length=336, Percent_Identity=24.1071428571429, Blast_Score=67, Evalue=3e-11,
Organism=Escherichia coli, GI87081854, Length=373, Percent_Identity=26.2734584450402, Blast_Score=102, Evalue=5e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006153 [H]

Pfam domain/function: PF00999 Na_H_Exchanger [H]

EC number: NA

Molecular weight: Translated: 46292; Mature: 46292

Theoretical pI: Translated: 9.46; Mature: 9.46

Prosite motif: PS00217 SUGAR_TRANSPORT_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKMETNVILSANNILKLIALVILAGVVFGKISRKVNLPDVVLFILAGVILGPEVLNLINI
CCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCHHHHHHCCC
DSYPVGNQLILTFGAAYILYDGGREIDLKVFNEVKISVLLLSTLGVLISTGITGFFVYKI
CCCCCCCEEEEEECCEEEEECCCCEEEEEEHHHHHHHHHHHHHHHHHHHHCHHHHHHHHH
FHIDFIYALLLGAIISSTDPSVLVPLFKNMNVSNKLKQTIISESAFNDAAAAIVTFAILG
HHHHHHHHHHHHHHHCCCCCCEEHHHHHCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHH
VIAGGEFSLGKSIFELLKSSLGGILIGGIFGYISTKLIAGEKYAFLKEFPSEVSIVAVIG
HHCCCCHHHHHHHHHHHHHHCCCEEHHHHHHHHHHHHHCCCHHHHHHHCCCHHHHHHHHH
TYLIADKLGVSGFMAVFIIGMVCGNKKRINCCIPDEYNQTHLRFKEVLTIILRMMIFVLL
HHHHHHHCCHHHHHHHHHHHHHCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHH
GSHIDFGVLSKYFTKDLMVVALLIFVSRPVSAFLSVIFDRKAKWNIKEIIYLMWVRETGV
CCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCC
IPAALVGMLLTMHIKNSDIIASVTFITIIITLTFQASTSKSLAKLLKLDLDEGKKEIAVD
CHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHEECCCCHHHHHHHHHHHHCCCCHHHCCC
SIKI
CCCC
>Mature Secondary Structure
MKMETNVILSANNILKLIALVILAGVVFGKISRKVNLPDVVLFILAGVILGPEVLNLINI
CCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCHHHHHHCCC
DSYPVGNQLILTFGAAYILYDGGREIDLKVFNEVKISVLLLSTLGVLISTGITGFFVYKI
CCCCCCCEEEEEECCEEEEECCCCEEEEEEHHHHHHHHHHHHHHHHHHHHCHHHHHHHHH
FHIDFIYALLLGAIISSTDPSVLVPLFKNMNVSNKLKQTIISESAFNDAAAAIVTFAILG
HHHHHHHHHHHHHHHCCCCCCEEHHHHHCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHH
VIAGGEFSLGKSIFELLKSSLGGILIGGIFGYISTKLIAGEKYAFLKEFPSEVSIVAVIG
HHCCCCHHHHHHHHHHHHHHCCCEEHHHHHHHHHHHHHCCCHHHHHHHCCCHHHHHHHHH
TYLIADKLGVSGFMAVFIIGMVCGNKKRINCCIPDEYNQTHLRFKEVLTIILRMMIFVLL
HHHHHHHCCHHHHHHHHHHHHHCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHH
GSHIDFGVLSKYFTKDLMVVALLIFVSRPVSAFLSVIFDRKAKWNIKEIIYLMWVRETGV
CCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCC
IPAALVGMLLTMHIKNSDIIASVTFITIIITLTFQASTSKSLAKLLKLDLDEGKKEIAVD
CHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHEECCCCHHHHHHHHHHHHCCCCHHHCCC
SIKI
CCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]