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The map label for this gene is resE [H]

Identifier: 148378343

GI number: 148378343

Start: 392421

End: 394274

Strand: Direct

Name: resE [H]

Synonym: CBO0340

Alternate gene names: 148378343

Gene position: 392421-394274 (Clockwise)

Preceding gene: 148378342

Following gene: 148378344

Centisome position: 10.1

GC content: 22.87

Gene sequence:

>1854_bases
ATGAGTGAAATTAATAAGAGTAGAGAAAAAAATATATATAGTATAACTTGTACAGTAAAATTAGCATCCTTACTTTTTTC
TTCTATAATACTATATAATTATGTATCTCAAAACAATTGTGCTAGCAAAAATAGTTATTATAATGTTTTATTACCAATGA
TATTATCGTTAATAACCAGTCTAATATATTTAATTTGGTCTTTTTTTACTGTAAAGACCAGAATGTTTAAAAATATATTA
TTTATACAGAGAATAGAAAATATATTTTTTATTTTAATTTTTACAATTTTGATTATAATGTCAGGAAAGTATAATAGTCA
TTATAAGTATTTATTTTTATTTATTATAATTACAACTACTATCCAAAGAGGATTAAAGTCTGGTATGATTATTTCGATAA
TATCATCTGTTATAATTTTAACTATAGATTTATCTATGGCTAATTATAATTGCATAAATACTTATTTTGAAAATGATTTA
ATTCTCTCAGGAGTATTTATTTTAACAGCTGTATCTTTGGGCTATTATGTTAAATTAGGGAATGAGAGTATAAAAGAAAA
AAATATTCAATTAGAAGACTTAAACAAAAAATTAAATGAAAAGGATAGTCAGAGAAAATATATAGAGGAGTTGCTTTTTA
AAAACGATACTTGCTATAATTTACTTATAGAGAATGCAAGAGATGCTATTATAATACATAGGAAAGATAAGATTGTTTTT
GCTAATGAAAGTGCAGCAGAACTGTTAATTTGTAGTAATAATAATGAACTTCAAAATTTAAATATAAATAGTTTTATATT
AAAAGAAGAACAAAAGAAAATAAGAAATAAATTAGAATTAGTATATAGAAATAAGAGAGATATAGTATGTGTTGAGCAAG
TTATTCAAAATAATAAAAGAAAAAAGATAAATGTTGAAAGTATAAGTACTTATATTATATATAATAATAAACCTGCTATA
TTATCTATACTAAGAGATATTACTTCACAAAAACAGGTAGAAAAACTTCAAAAGGATGTAGAAAAAAATATAGAATTGCT
AAATGAAAGTAGAGAATATAATAAATTAATAACTGATTTTTTAGCAAACATATCTCATGAATTAAAAACACCTTTAAATG
TAATATTTACAGCAGTGCAGATATTAGATTTATATAAAAAAGATGCAGAATCCTATGACAAAAAGGAACAGTATATAAAA
GTTATAAAGCAAAACTGCTATAGGCTTATGAGGTTAATTAATAATTTATTGGATACAACTAAGTTAGATTCAGGATATTT
AAAACTTAATTTAGTAAATTGTAATATAGTAAATTTAGTAGAAGAGATTACTTTATCAGTTGTATATTATGCAGAAAGCA
AAAATATAAATATTATATTTGATACAGATGTTGAAGAAAAGATTATGGCTGTTGATCCAGATAAAATAGAAAGAATAGTA
CTAAATTTATTATCTAATGCTATAAAATTTACAGGTAGTGGTGGAAATATATATGTAACTGTTAAAGATTTTGAAGATAA
TATTATTATATCTGTAAAAGATACAGGTATAGGTATACCAAGGGACAAAATAGAAAATATATTTGATAGATTTGTTCAAG
TAGATAAAACTTTAAGAAGAAATAAGGAAGGCAGCGGCATAGGACTATATTTGGTTAAATCCTTTGTAAATATGCATGAA
GGTACTATAGATATTCAAAGTGAGATAGGAAAAGGTAGCGAATTTATAATAAATATACCAGTTAAATTAGTAAAAGAAGA
TTTAGAAAAAGAAAATAATGTGTTTTATTCACCAAGCAAAGAATATGTAGATATGGAATTTGCAGATATTTATTCCGAGG
TCTCATCCAAATAG

Upstream 100 bases:

>100_bases
AAATCATTAAGAAAATAAAGTTTTTAAATAGTGTATAAGGGGGGAGACCTGCTTATACACTATATGTTTATATATTAATA
TGACTGTGAGTGTGAGGGAT

Downstream 100 bases:

>100_bases
ATTATTTTTATATCTATAATTTTATTTAGTTTTGCATAAACTCCTTTAATCAAATTTAATTTTTATTAGAATCCATTATA
TGAATCATTAGTGTTTTTAA

Product: two-component sensor kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 617; Mature: 616

Protein sequence:

>617_residues
MSEINKSREKNIYSITCTVKLASLLFSSIILYNYVSQNNCASKNSYYNVLLPMILSLITSLIYLIWSFFTVKTRMFKNIL
FIQRIENIFFILIFTILIIMSGKYNSHYKYLFLFIIITTTIQRGLKSGMIISIISSVIILTIDLSMANYNCINTYFENDL
ILSGVFILTAVSLGYYVKLGNESIKEKNIQLEDLNKKLNEKDSQRKYIEELLFKNDTCYNLLIENARDAIIIHRKDKIVF
ANESAAELLICSNNNELQNLNINSFILKEEQKKIRNKLELVYRNKRDIVCVEQVIQNNKRKKINVESISTYIIYNNKPAI
LSILRDITSQKQVEKLQKDVEKNIELLNESREYNKLITDFLANISHELKTPLNVIFTAVQILDLYKKDAESYDKKEQYIK
VIKQNCYRLMRLINNLLDTTKLDSGYLKLNLVNCNIVNLVEEITLSVVYYAESKNINIIFDTDVEEKIMAVDPDKIERIV
LNLLSNAIKFTGSGGNIYVTVKDFEDNIIISVKDTGIGIPRDKIENIFDRFVQVDKTLRRNKEGSGIGLYLVKSFVNMHE
GTIDIQSEIGKGSEFIINIPVKLVKEDLEKENNVFYSPSKEYVDMEFADIYSEVSSK

Sequences:

>Translated_617_residues
MSEINKSREKNIYSITCTVKLASLLFSSIILYNYVSQNNCASKNSYYNVLLPMILSLITSLIYLIWSFFTVKTRMFKNIL
FIQRIENIFFILIFTILIIMSGKYNSHYKYLFLFIIITTTIQRGLKSGMIISIISSVIILTIDLSMANYNCINTYFENDL
ILSGVFILTAVSLGYYVKLGNESIKEKNIQLEDLNKKLNEKDSQRKYIEELLFKNDTCYNLLIENARDAIIIHRKDKIVF
ANESAAELLICSNNNELQNLNINSFILKEEQKKIRNKLELVYRNKRDIVCVEQVIQNNKRKKINVESISTYIIYNNKPAI
LSILRDITSQKQVEKLQKDVEKNIELLNESREYNKLITDFLANISHELKTPLNVIFTAVQILDLYKKDAESYDKKEQYIK
VIKQNCYRLMRLINNLLDTTKLDSGYLKLNLVNCNIVNLVEEITLSVVYYAESKNINIIFDTDVEEKIMAVDPDKIERIV
LNLLSNAIKFTGSGGNIYVTVKDFEDNIIISVKDTGIGIPRDKIENIFDRFVQVDKTLRRNKEGSGIGLYLVKSFVNMHE
GTIDIQSEIGKGSEFIINIPVKLVKEDLEKENNVFYSPSKEYVDMEFADIYSEVSSK
>Mature_616_residues
SEINKSREKNIYSITCTVKLASLLFSSIILYNYVSQNNCASKNSYYNVLLPMILSLITSLIYLIWSFFTVKTRMFKNILF
IQRIENIFFILIFTILIIMSGKYNSHYKYLFLFIIITTTIQRGLKSGMIISIISSVIILTIDLSMANYNCINTYFENDLI
LSGVFILTAVSLGYYVKLGNESIKEKNIQLEDLNKKLNEKDSQRKYIEELLFKNDTCYNLLIENARDAIIIHRKDKIVFA
NESAAELLICSNNNELQNLNINSFILKEEQKKIRNKLELVYRNKRDIVCVEQVIQNNKRKKINVESISTYIIYNNKPAIL
SILRDITSQKQVEKLQKDVEKNIELLNESREYNKLITDFLANISHELKTPLNVIFTAVQILDLYKKDAESYDKKEQYIKV
IKQNCYRLMRLINNLLDTTKLDSGYLKLNLVNCNIVNLVEEITLSVVYYAESKNINIIFDTDVEEKIMAVDPDKIERIVL
NLLSNAIKFTGSGGNIYVTVKDFEDNIIISVKDTGIGIPRDKIENIFDRFVQVDKTLRRNKEGSGIGLYLVKSFVNMHEG
TIDIQSEIGKGSEFIINIPVKLVKEDLEKENNVFYSPSKEYVDMEFADIYSEVSSK

Specific function: Member of the two-component regulatory system resD/resE involved in the global regulation of aerobic and anaerobic respiration. Probably phosphorylates resD [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI145693157, Length=302, Percent_Identity=29.1390728476821, Blast_Score=129, Evalue=4e-31,
Organism=Escherichia coli, GI1789149, Length=267, Percent_Identity=29.2134831460674, Blast_Score=124, Evalue=2e-29,
Organism=Escherichia coli, GI48994928, Length=371, Percent_Identity=26.4150943396226, Blast_Score=114, Evalue=2e-26,
Organism=Escherichia coli, GI1788713, Length=261, Percent_Identity=29.1187739463602, Blast_Score=112, Evalue=6e-26,
Organism=Escherichia coli, GI1786600, Length=277, Percent_Identity=26.7148014440433, Blast_Score=111, Evalue=2e-25,
Organism=Escherichia coli, GI1790436, Length=247, Percent_Identity=30.7692307692308, Blast_Score=111, Evalue=2e-25,
Organism=Escherichia coli, GI1786912, Length=244, Percent_Identity=29.9180327868852, Blast_Score=105, Evalue=9e-24,
Organism=Escherichia coli, GI1786783, Length=227, Percent_Identity=28.6343612334802, Blast_Score=104, Evalue=1e-23,
Organism=Escherichia coli, GI1788393, Length=265, Percent_Identity=23.3962264150943, Blast_Score=92, Evalue=1e-19,
Organism=Escherichia coli, GI1788549, Length=399, Percent_Identity=24.5614035087719, Blast_Score=92, Evalue=1e-19,
Organism=Escherichia coli, GI1790300, Length=235, Percent_Identity=26.8085106382979, Blast_Score=82, Evalue=1e-16,
Organism=Escherichia coli, GI87082128, Length=225, Percent_Identity=28, Blast_Score=80, Evalue=4e-16,
Organism=Escherichia coli, GI1790861, Length=256, Percent_Identity=26.171875, Blast_Score=77, Evalue=4e-15,
Organism=Escherichia coli, GI1790346, Length=249, Percent_Identity=24.4979919678715, Blast_Score=75, Evalue=1e-14,
Organism=Escherichia coli, GI1787894, Length=220, Percent_Identity=27.7272727272727, Blast_Score=69, Evalue=6e-13,
Organism=Escherichia coli, GI1787374, Length=261, Percent_Identity=28.735632183908, Blast_Score=69, Evalue=9e-13,
Organism=Escherichia coli, GI1789403, Length=250, Percent_Identity=23.2, Blast_Score=66, Evalue=6e-12,
Organism=Escherichia coli, GI1788279, Length=237, Percent_Identity=28.6919831223629, Blast_Score=65, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6322044, Length=116, Percent_Identity=34.4827586206897, Blast_Score=75, Evalue=3e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR000014
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 71398; Mature: 71267

Theoretical pI: Translated: 8.13; Mature: 8.13

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSEINKSREKNIYSITCTVKLASLLFSSIILYNYVSQNNCASKNSYYNVLLPMILSLITS
CCCCCCHHCCCEEEEEHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHH
LIYLIWSFFTVKTRMFKNILFIQRIENIFFILIFTILIIMSGKYNSHYKYLFLFIIITTT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHH
IQRGLKSGMIISIISSVIILTIDLSMANYNCINTYFENDLILSGVFILTAVSLGYYVKLG
HHHHHHCCHHHHHHHHHHHEEEEECCCCCHHHHHHHCCCHHHHHHHHHHHHHHHHEEEEC
NESIKEKNIQLEDLNKKLNEKDSQRKYIEELLFKNDTCYNLLIENARDAIIIHRKDKIVF
CCHHHHCCCHHHHHHHHHCCCHHHHHHHHHHHHCCCCHHHHHHHCCCCEEEEEECCEEEE
ANESAAELLICSNNNELQNLNINSFILKEEQKKIRNKLELVYRNKRDIVCVEQVIQNNKR
ECCCCCEEEEECCCCCEEECCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCC
KKINVESISTYIIYNNKPAILSILRDITSQKQVEKLQKDVEKNIELLNESREYNKLITDF
CEEEHEEEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHH
LANISHELKTPLNVIFTAVQILDLYKKDAESYDKKEQYIKVIKQNCYRLMRLINNLLDTT
HHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
KLDSGYLKLNLVNCNIVNLVEEITLSVVYYAESKNINIIFDTDVEEKIMAVDPDKIERIV
CCCCCEEEEEEECCHHHHHHHHHHEEEEEEEECCCEEEEECCCCCCCEEECCHHHHHHHH
LNLLSNAIKFTGSGGNIYVTVKDFEDNIIISVKDTGIGIPRDKIENIFDRFVQVDKTLRR
HHHHHHHHEEECCCCEEEEEEEECCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHC
NKEGSGIGLYLVKSFVNMHEGTIDIQSEIGKGSEFIINIPVKLVKEDLEKENNVFYSPSK
CCCCCCCHHHHHHHHHHHCCCCEEEHHHCCCCCEEEEECCHHHHHHHHHHCCCEEECCCC
EYVDMEFADIYSEVSSK
CCCCHHHHHHHHHHHCC
>Mature Secondary Structure 
SEINKSREKNIYSITCTVKLASLLFSSIILYNYVSQNNCASKNSYYNVLLPMILSLITS
CCCCCHHCCCEEEEEHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHH
LIYLIWSFFTVKTRMFKNILFIQRIENIFFILIFTILIIMSGKYNSHYKYLFLFIIITTT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHH
IQRGLKSGMIISIISSVIILTIDLSMANYNCINTYFENDLILSGVFILTAVSLGYYVKLG
HHHHHHCCHHHHHHHHHHHEEEEECCCCCHHHHHHHCCCHHHHHHHHHHHHHHHHEEEEC
NESIKEKNIQLEDLNKKLNEKDSQRKYIEELLFKNDTCYNLLIENARDAIIIHRKDKIVF
CCHHHHCCCHHHHHHHHHCCCHHHHHHHHHHHHCCCCHHHHHHHCCCCEEEEEECCEEEE
ANESAAELLICSNNNELQNLNINSFILKEEQKKIRNKLELVYRNKRDIVCVEQVIQNNKR
ECCCCCEEEEECCCCCEEECCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCC
KKINVESISTYIIYNNKPAILSILRDITSQKQVEKLQKDVEKNIELLNESREYNKLITDF
CEEEHEEEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHH
LANISHELKTPLNVIFTAVQILDLYKKDAESYDKKEQYIKVIKQNCYRLMRLINNLLDTT
HHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
KLDSGYLKLNLVNCNIVNLVEEITLSVVYYAESKNINIIFDTDVEEKIMAVDPDKIERIV
CCCCCEEEEEEECCHHHHHHHHHHEEEEEEEECCCEEEEECCCCCCCEEECCHHHHHHHH
LNLLSNAIKFTGSGGNIYVTVKDFEDNIIISVKDTGIGIPRDKIENIFDRFVQVDKTLRR
HHHHHHHHEEECCCCEEEEEEEECCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHC
NKEGSGIGLYLVKSFVNMHEGTIDIQSEIGKGSEFIINIPVKLVKEDLEKENNVFYSPSK
CCCCCCCHHHHHHHHHHHCCCCEEEHHHCCCCCEEEEECCHHHHHHHHHHCCCEEECCCC
EYVDMEFADIYSEVSSK
CCCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7934829; 9384377; 8631715 [H]