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The map label for this gene is malX [H]

Identifier: 148378290

GI number: 148378290

Start: 337567

End: 339162

Strand: Direct

Name: malX [H]

Synonym: CBO0288

Alternate gene names: 148378290

Gene position: 337567-339162 (Clockwise)

Preceding gene: 148378289

Following gene: 148378291

Centisome position: 8.68

GC content: 30.58

Gene sequence:

>1596_bases
ATGGGGGTTACAATGATGAAAGAAAAGATATTAAATCAATTACAAAACTTTTCTAAAGGAATGTTTGTTCCTGTATTGAT
ATTACCAATAGCCGGTATAATAATTGCAATAGGGAACATTTTAACAAATGCAAAACTAGCAGAATACCTTCCATTTTTAA
AGAATGGAATGGTATTTGGATTAGGAAAAATGTTATCTGGTTCATTAGTTTCAATTTTAACTAATTTAGGAATTATATTC
TGTGTTGGTCTTGCAGTAGGACTTTCTAAGAAAAAGAAAGCAGAAGCAGGATTTACATCACTTTTAGTATTTTTAGTATT
TATAAATGCAATGAACATTTTTTTAGAATTAAATAATAGATTAGCACCACAAGATGCCTTAAGGGGATCTGGCCAAACTA
TGGTTTTAGGTGTTCAAGTTCTTGATATGGGAGTTTTCTTAGGAATTATTTTAGGTATTGTTGTTGCTTATATACATAAT
AGATTTTGTGAAAAAGAATTTGATGGAGCTTTTCAAATTTATGGTGGTTCAAGATTAGTATTTATAATATTAATACCTAT
TACTGTTTTTTTAGCAATAATATTGAGTTATGTTTGGCCTTCAGTACAATATTTAATTTCAAGTCTTGGTAATTTTATAA
CAGGAGCAGGAAATTTTGGTATATTTACTTATGGTACTTTAGAGAGATTACTTATTCCTACTGGATTGCATCACTTAGTT
TATACTCCATTTTTATATAGTCCTTTAGGTGGAGTGGCTGAAATAGGAGGAAAAGTATTTGAAGGAGCAAGAAATATATA
CTTTGCAGAAATGGCTGATCCTAATATAGCAAAATTATCAGCATCAGTAATTTGGGATGCTAGAGGATTGTCAAAAATGT
TTGGTTTAATTGGTGCATGTTTGGCTATGTACCATACAGCATTACCAGAGAATAAGTCTAAGATAAAGGCAATTTTAATT
CCAGCTGCGGTTACATCAATATTAGCAGGAGTAACAGAGCCAATAGAATTTTCATTTATGTTCGTAGCACCAATATTATT
TGTTATACATGCCGTCTTAAGTGGATTGGGAATGGTGGTATTAAATATTCTTGGAGTTACAGCTATAGGTCCAAATGGGT
TAATAGACTTCTTATTATACAACATACCTCTTGGAGTTGCCAAAACAGGATGGCCAATGTTTATTTTGATCGGTTTAGGA
CAATTCGTTGTATATTATGTTATATTCAGATTTTTAATAGTTAAGTTTAAACTTAAGACTCCAGGAAGAGAAGAAGATGG
AAATACAAAGTTATATAGTAAAAAAGATTATAAAGAAAAGTCTAAAGCAAATACAAAGTCAGGTGATTCAAGTATTGCGC
CAATTGTAGTAGAAGGTTTAGGTGGCAAGGATAATATATTAAAAGTTGATAATTGTTACACTAGATTGAGATTAGTGGTA
AAAGATTCTTCATTAGTTAATGAACAATTATTAAAAAATGAAACAGCAGCAAATGGAGTAATAATTAAAGGAGAAAACGT
ACAGGTTGTCTATGGCTTAAAGGTAACAAGTGTAAGAAAGAGCGTAGACGAGTATCTTGGAATAGAATCAAATTAG

Upstream 100 bases:

>100_bases
ATCTAAAGAGGTAACACGTTTTTTACATAAGAAAATCTATATACATATAGATATCTAATTATTATAATGTGAAATGTAAA
TGGTTTCTCAAAAATAAATA

Downstream 100 bases:

>100_bases
AGTAAAAAATTTAGTTAGGAGTGACTATTAATTTAGTCACTCTTATAAAAATATAGTTATAATTTGAATAAAAATTCCAT
TAATTATGAAACAGGTTGTT

Product: PTS system, glucose/maltose-specfic, IIBC component

Products: NA

Alternate protein names: Maltose and glucose permease IIC component; PTS system maltose- and glucose-specific EIIC component; Maltose- and glucose-specific phosphotransferase enzyme IIB component; PTS system maltose- and glucose-specific EIIB component [H]

Number of amino acids: Translated: 531; Mature: 530

Protein sequence:

>531_residues
MGVTMMKEKILNQLQNFSKGMFVPVLILPIAGIIIAIGNILTNAKLAEYLPFLKNGMVFGLGKMLSGSLVSILTNLGIIF
CVGLAVGLSKKKKAEAGFTSLLVFLVFINAMNIFLELNNRLAPQDALRGSGQTMVLGVQVLDMGVFLGIILGIVVAYIHN
RFCEKEFDGAFQIYGGSRLVFIILIPITVFLAIILSYVWPSVQYLISSLGNFITGAGNFGIFTYGTLERLLIPTGLHHLV
YTPFLYSPLGGVAEIGGKVFEGARNIYFAEMADPNIAKLSASVIWDARGLSKMFGLIGACLAMYHTALPENKSKIKAILI
PAAVTSILAGVTEPIEFSFMFVAPILFVIHAVLSGLGMVVLNILGVTAIGPNGLIDFLLYNIPLGVAKTGWPMFILIGLG
QFVVYYVIFRFLIVKFKLKTPGREEDGNTKLYSKKDYKEKSKANTKSGDSSIAPIVVEGLGGKDNILKVDNCYTRLRLVV
KDSSLVNEQLLKNETAANGVIIKGENVQVVYGLKVTSVRKSVDEYLGIESN

Sequences:

>Translated_531_residues
MGVTMMKEKILNQLQNFSKGMFVPVLILPIAGIIIAIGNILTNAKLAEYLPFLKNGMVFGLGKMLSGSLVSILTNLGIIF
CVGLAVGLSKKKKAEAGFTSLLVFLVFINAMNIFLELNNRLAPQDALRGSGQTMVLGVQVLDMGVFLGIILGIVVAYIHN
RFCEKEFDGAFQIYGGSRLVFIILIPITVFLAIILSYVWPSVQYLISSLGNFITGAGNFGIFTYGTLERLLIPTGLHHLV
YTPFLYSPLGGVAEIGGKVFEGARNIYFAEMADPNIAKLSASVIWDARGLSKMFGLIGACLAMYHTALPENKSKIKAILI
PAAVTSILAGVTEPIEFSFMFVAPILFVIHAVLSGLGMVVLNILGVTAIGPNGLIDFLLYNIPLGVAKTGWPMFILIGLG
QFVVYYVIFRFLIVKFKLKTPGREEDGNTKLYSKKDYKEKSKANTKSGDSSIAPIVVEGLGGKDNILKVDNCYTRLRLVV
KDSSLVNEQLLKNETAANGVIIKGENVQVVYGLKVTSVRKSVDEYLGIESN
>Mature_530_residues
GVTMMKEKILNQLQNFSKGMFVPVLILPIAGIIIAIGNILTNAKLAEYLPFLKNGMVFGLGKMLSGSLVSILTNLGIIFC
VGLAVGLSKKKKAEAGFTSLLVFLVFINAMNIFLELNNRLAPQDALRGSGQTMVLGVQVLDMGVFLGIILGIVVAYIHNR
FCEKEFDGAFQIYGGSRLVFIILIPITVFLAIILSYVWPSVQYLISSLGNFITGAGNFGIFTYGTLERLLIPTGLHHLVY
TPFLYSPLGGVAEIGGKVFEGARNIYFAEMADPNIAKLSASVIWDARGLSKMFGLIGACLAMYHTALPENKSKIKAILIP
AAVTSILAGVTEPIEFSFMFVAPILFVIHAVLSGLGMVVLNILGVTAIGPNGLIDFLLYNIPLGVAKTGWPMFILIGLGQ
FVVYYVIFRFLIVKFKLKTPGREEDGNTKLYSKKDYKEKSKANTKSGDSSIAPIVVEGLGGKDNILKVDNCYTRLRLVVK
DSSLVNEQLLKNETAANGVIIKGENVQVVYGLKVTSVRKSVDEYLGIESN

Specific function: MalX encodes a phosphotransferase system enzyme II that can recognize glucose and maltose as substrates even though these sugars may not represent the natural substrates of the system [H]

COG id: COG1263

COG function: function code G; Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PTS EIIC type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1787908, Length=534, Percent_Identity=37.4531835205993, Blast_Score=327, Evalue=1e-90,
Organism=Escherichia coli, GI1787343, Length=528, Percent_Identity=35.4166666666667, Blast_Score=278, Evalue=6e-76,
Organism=Escherichia coli, GI1786894, Length=523, Percent_Identity=32.1223709369025, Blast_Score=217, Evalue=2e-57,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018113
- InterPro:   IPR004719
- InterPro:   IPR001996
- InterPro:   IPR003352
- InterPro:   IPR013013
- InterPro:   IPR011535
- InterPro:   IPR011301 [H]

Pfam domain/function: PF00367 PTS_EIIB; PF02378 PTS_EIIC [H]

EC number: =2.7.1.69 [H]

Molecular weight: Translated: 57618; Mature: 57487

Theoretical pI: Translated: 9.67; Mature: 9.67

Prosite motif: PS00079 MULTICOPPER_OXIDASE1 ; PS01035 PTS_EIIB_TYPE_1_CYS ; PS51098 PTS_EIIB_TYPE_1 ; PS51103 PTS_EIIC_TYPE_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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CCHHHHHHHHHHCCCCCCCEEEECCCEEEEEECCHHHHHHHHHHHCCCCCC
>Mature Secondary Structure 
GVTMMKEKILNQLQNFSKGMFVPVLILPIAGIIIAIGNILTNAKLAEYLPFLKNGMVFG
CCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHEE
LGKMLSGSLVSILTNLGIIFCVGLAVGLSKKKKAEAGFTSLLVFLVFINAMNIFLELNNR
HHHHHCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
LAPQDALRGSGQTMVLGVQVLDMGVFLGIILGIVVAYIHNRFCEKEFDGAFQIYGGSRLV
CCCHHHHCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCEEE
FIILIPITVFLAIILSYVWPSVQYLISSLGNFITGAGNFGIFTYGTLERLLIPTGLHHLV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEHHHHHHHHHHCCHHHHH
YTPFLYSPLGGVAEIGGKVFEGARNIYFAEMADPNIAKLSASVIWDARGLSKMFGLIGAC
HHHHHHCCCCCHHHHCHHHHHCCCCEEEEECCCCCHHHHHHHHHCCHHHHHHHHHHHHHH
LAMYHTALPENKSKIKAILIPAAVTSILAGVTEPIEFSFMFVAPILFVIHAVLSGLGMVV
HHHHHHHCCCCCCHHEEEEHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
LNILGVTAIGPNGLIDFLLYNIPLGVAKTGWPMFILIGLGQFVVYYVIFRFLIVKFKLKT
HHHHHHHCCCCCHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHEEECC
PGREEDGNTKLYSKKDYKEKSKANTKSGDSSIAPIVVEGLGGKDNILKVDNCYTRLRLVV
CCCCCCCCCCCCCCHHHHHHHHCCCCCCCCCCCCEEEECCCCCCCEEEHHHHHHHHEEEE
KDSSLVNEQLLKNETAANGVIIKGENVQVVYGLKVTSVRKSVDEYLGIESN
CCHHHHHHHHHHCCCCCCCEEEECCCEEEEEECCHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1856179; 9097039; 9278503; 2670898 [H]