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The map label for this gene is atpB [H]

Identifier: 148361328

GI number: 148361328

Start: 3557229

End: 3558056

Strand: Reverse

Name: atpB [H]

Synonym: LPC_3303

Alternate gene names: 148361328

Gene position: 3558056-3557229 (Counterclockwise)

Preceding gene: 148361329

Following gene: 148361327

Centisome position: 99.49

GC content: 35.99

Gene sequence:

>828_bases
ATGGTATCTAGCACAAACTATATTAAGCATCATTTAACGTACCTTACCTATAACGTAAATGATATGACATTCGGTTCAAG
TGGTGGTTTTTGGACCTTGAACCTGGATACAATCTTCTTTTCTATAGCCTTGGGTCTAATTGCTCTGGCAATTATGTATT
TAGCGGCAAGGAAAGTAACCACTGGTGTTCCTGGAAAGTTACAAAATTTTGCTGAGCTCATGCTCGAGTTTGCTGATAAT
CAGGTTAAAGATTGTTTTCATGGAAAAAATAACTTAATAGGTCCATTGGCATTAACTATCTTTATGTGGGTATTCCTGAT
GAATTTTATGGATATCGTGCCAGTAGATATCCTTCCTGTACTTGCGCAGCTAGTCGGTATACACTACCTGAAAGTTGTAC
CAACTAATGACTTGAATTTGACTTTTGGATTGTCACTTTCCGTATTTCTTCTAATAGTTTTTTACAGTTTAAAAATAAAA
GGCGTTAAAGGTTTTGTTAAAGAGCTCACCCTGCAGCCCTTCAATCACCCACTATTCATTCCATTTAATTTATTGTTGGA
GTTGGTTGGGCTGATAGCTAAACCCATTTCCTTGGCATTACGACTTTTTGGTAACTTATACGCTGGCGAATTAATATTTA
TTTTGATAGCCTTACTAACCTTAAATGCAACAACGTCATCATTAATTAGTACTATGACACTGGGTACGGCGCAATTTATT
CTTGCACTCGCCTGGTCCATTTTCCATATATTAGTGATAACCTTACAAGCATTTATTTTTATGGTACTGACTATAGTTTA
TTTGAGTTTGGCCCATGAAGATCATTAA

Upstream 100 bases:

>100_bases
CCGGCAGCGTTTTTTGCATCATACATTTTGGTTCTTATGACGCATTGGTTTGCCCCATGGATTATTGTCAATAAACAGAA
TAGGCCAAAAAGTGACTGAA

Downstream 100 bases:

>100_bases
CCGATTTAATTATCATCATCCATTGTAAAGGGGATAAAATATGCAAGCTGCTGAATTAATAGCACAAGTTCAAAGTATGA
CCGTCATTGCGGTTGCCTTG

Product: F0F1 ATP synthase subunit A

Products: ATP; H+; H2O [C]

Alternate protein names: ATP synthase F0 sector subunit a; F-ATPase subunit 6 [H]

Number of amino acids: Translated: 275; Mature: 275

Protein sequence:

>275_residues
MVSSTNYIKHHLTYLTYNVNDMTFGSSGGFWTLNLDTIFFSIALGLIALAIMYLAARKVTTGVPGKLQNFAELMLEFADN
QVKDCFHGKNNLIGPLALTIFMWVFLMNFMDIVPVDILPVLAQLVGIHYLKVVPTNDLNLTFGLSLSVFLLIVFYSLKIK
GVKGFVKELTLQPFNHPLFIPFNLLLELVGLIAKPISLALRLFGNLYAGELIFILIALLTLNATTSSLISTMTLGTAQFI
LALAWSIFHILVITLQAFIFMVLTIVYLSLAHEDH

Sequences:

>Translated_275_residues
MVSSTNYIKHHLTYLTYNVNDMTFGSSGGFWTLNLDTIFFSIALGLIALAIMYLAARKVTTGVPGKLQNFAELMLEFADN
QVKDCFHGKNNLIGPLALTIFMWVFLMNFMDIVPVDILPVLAQLVGIHYLKVVPTNDLNLTFGLSLSVFLLIVFYSLKIK
GVKGFVKELTLQPFNHPLFIPFNLLLELVGLIAKPISLALRLFGNLYAGELIFILIALLTLNATTSSLISTMTLGTAQFI
LALAWSIFHILVITLQAFIFMVLTIVYLSLAHEDH
>Mature_275_residues
MVSSTNYIKHHLTYLTYNVNDMTFGSSGGFWTLNLDTIFFSIALGLIALAIMYLAARKVTTGVPGKLQNFAELMLEFADN
QVKDCFHGKNNLIGPLALTIFMWVFLMNFMDIVPVDILPVLAQLVGIHYLKVVPTNDLNLTFGLSLSVFLLIVFYSLKIK
GVKGFVKELTLQPFNHPLFIPFNLLLELVGLIAKPISLALRLFGNLYAGELIFILIALLTLNATTSSLISTMTLGTAQFI
LALAWSIFHILVITLQAFIFMVLTIVYLSLAHEDH

Specific function: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane [H]

COG id: COG0356

COG function: function code C; F0F1-type ATP synthase, subunit a

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATPase A chain family [H]

Homologues:

Organism=Escherichia coli, GI1790176, Length=279, Percent_Identity=53.405017921147, Blast_Score=281, Evalue=4e-77,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000568
- InterPro:   IPR023011 [H]

Pfam domain/function: PF00119 ATP-synt_A [H]

EC number: 3.6.3.14 [C]

Molecular weight: Translated: 30621; Mature: 30621

Theoretical pI: Translated: 7.29; Mature: 7.29

Prosite motif: PS00449 ATPASE_A

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVSSTNYIKHHLTYLTYNVNDMTFGSSGGFWTLNLDTIFFSIALGLIALAIMYLAARKVT
CCCCHHHHHHHHHHEEEECCCEEECCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHC
TGVPGKLQNFAELMLEFADNQVKDCFHGKNNLIGPLALTIFMWVFLMNFMDIVPVDILPV
CCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHH
LAQLVGIHYLKVVPTNDLNLTFGLSLSVFLLIVFYSLKIKGVKGFVKELTLQPFNHPLFI
HHHHHHHHHEEEEECCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEE
PFNLLLELVGLIAKPISLALRLFGNLYAGELIFILIALLTLNATTSSLISTMTLGTAQFI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHH
LALAWSIFHILVITLQAFIFMVLTIVYLSLAHEDH
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MVSSTNYIKHHLTYLTYNVNDMTFGSSGGFWTLNLDTIFFSIALGLIALAIMYLAARKVT
CCCCHHHHHHHHHHEEEECCCEEECCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHC
TGVPGKLQNFAELMLEFADNQVKDCFHGKNNLIGPLALTIFMWVFLMNFMDIVPVDILPV
CCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHH
LAQLVGIHYLKVVPTNDLNLTFGLSLSVFLLIVFYSLKIKGVKGFVKELTLQPFNHPLFI
HHHHHHHHHEEEEECCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEE
PFNLLLELVGLIAKPISLALRLFGNLYAGELIFILIALLTLNATTSSLISTMTLGTAQFI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHH
LALAWSIFHILVITLQAFIFMVLTIVYLSLAHEDH
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: Borate; diphosphate; HCO3- [C]

Metal ions: Co2+; Fe2+; Mn2+; Zn2+ [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ADP; H+; Phosphate [C]

Specific reaction: ADP + (4) H+ + Phosphate <==> ATP + (3) H+ + H2O [C]

General reaction: Phosphorous acid anhydride hydrolysis [C]

Inhibitor: Ca2+; CN-; Efrapeptin; Ethidiumbromide; Guanidines analogs; Oligomycin; Quercetin; Trialkyl tin derivatives; Venturicidin [C]

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA