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The map label for this gene is atpA [H]

Identifier: 148361324

GI number: 148361324

Start: 3554276

End: 3555829

Strand: Reverse

Name: atpA [H]

Synonym: LPC_3299

Alternate gene names: 148361324

Gene position: 3555829-3554276 (Counterclockwise)

Preceding gene: 148361325

Following gene: 148361323

Centisome position: 99.42

GC content: 43.05

Gene sequence:

>1554_bases
ATGTCAGAACAAGTAGCGTTAAATCCTTCTGAAATCAGTGAATTAATCAGAAAGAAAATAGATCAATTTAGTGTGGTTTC
TGAAGCACGAAATGAAGGTACTATCGTTAGTCTGAAAGACGGTATTGTACGACTGCATGGGCTTGCCGATGTTATGGCAG
GTGAAATGATAGAGTTTCCAGGAGGGGTCTATGGATTGGCTCTTAACCTGAAGAGAGATTCTGTTGGTGCTGTAATATTA
GGCGACTCATCCACATTAGCTGAAGGGCAAAAAGGTAAATGTACAGGTCGTATTCTGGAAGTCCCAGTTGGAAAAGGTCT
TTTGGGACGTGTCGTTGATGCCTTAGGAAATCCTATAGACGGGAAAGGCCCGATAGAGTCATCTGGTATGTCTCCAATAG
AAAAAGTGGCTCCTGGTGTAGTTACACGTAAATCAATAGATCAACCTGTTCAGACAGGATTAAAAGCAATCGATGCGATG
ATCCCCGTTGGAAGAGGTCAGCGAGAGCTTATTATTGGTGACCGCCAAACTGGTAAAACTGCCATTGCTATTGATGCGAT
TATCAATCAAAAAGGTACCGGCGTTAAATGCGTATATGTAGCCATTGGCCAAAAGGCTTCATCCGTTGCATCGATTGTTA
GGAAATTGGAAGAGCATGGCGCTCTTGAGCATACTATTGTTGTGGTAGCGGGAGCCTCTGATTCAGCAGCACTCCAATAT
ATAGCACCTTACGCAGGTTGTACCATGGGTGAGTATTTCATGGAACGTGGGGAAGATGCATTGATTGTTTACGATGATTT
AACTAAACAAGCATGGGCATATAGACAGATCTCCTTGTTATTACGCCGGCCACCAGGTCGAGAAGCTTATCCTGGTGATA
TTTTCTATTTGCATTCTCGCTTGTTGGAAAGAGCGGCAAGAATTAATGCCGATGAAGTAGAAAAATTAACTAATGGAGAA
GTGAAGGGCAAAACAGGATCACTGACTGCATTACCGATTATCGAAACGCAAGCGGGAGATGTGTCAGCCTTCGTACCAAC
AAACGTAATCTCTATTACCGATGGGCAAATATTCCTTGATGTTGATTTATTTAACTCAGGTGTTAGACCAGCAATCAATT
CCGGACTATCCGTTTCACGAGTTGGTGGTGCTGCACAAACGAAAATCATGAAAAAGCTTGGTGGTGGTACTCGGCTTGCT
CTGGCACAATTCCGTGAGTTAGAAGCATTCTCCCAATTCGCATCTGATCTTGATGATGCAACACGTAAGCAGCTGGAGCG
TGGACAACGTATTACAGAGCTGATGAAACAAAAACAATACTCCCCACTTACAGTAGCTGAAATGGGGGTAAGCTTGTTTG
TGGTAGAAAAGGGATACTTGGACGATGTACCTGTAAATGAAATCAGCTCGTTTGAAGCTTCCTTGCACGATTACATGCGC
AGTACCCATGCCGCTTTATTACATGCAATTAATGAAGCCGGTGCTTATGATAATGAAATCGAAGCAAAACTGAAAAAAGC
AGTAGAAGAGTTCAAGAACACAGGCAGTTGGTAA

Upstream 100 bases:

>100_bases
CGCTAATTCGAGCAGGCGATTTAGTTATCGATGGTTCAGTTCGGGGCAAGCTTAATATGCTTGGCACCAGCTTGGCCGCT
TAATTTAGAGGATAGTTTCC

Downstream 100 bases:

>100_bases
GGTATAGCCTCAAAGAGTTAGCTCTTTGAGGCACAAAGGCCATTATTTGAAAGTAATGGCCTCTAAAACTAATTAAGGCG
AATTGAAAGATGGCTGGAGC

Product: F0F1 ATP synthase subunit alpha

Products: NA

Alternate protein names: ATP synthase F1 sector subunit alpha 2; F-ATPase subunit alpha 2 [H]

Number of amino acids: Translated: 517; Mature: 516

Protein sequence:

>517_residues
MSEQVALNPSEISELIRKKIDQFSVVSEARNEGTIVSLKDGIVRLHGLADVMAGEMIEFPGGVYGLALNLKRDSVGAVIL
GDSSTLAEGQKGKCTGRILEVPVGKGLLGRVVDALGNPIDGKGPIESSGMSPIEKVAPGVVTRKSIDQPVQTGLKAIDAM
IPVGRGQRELIIGDRQTGKTAIAIDAIINQKGTGVKCVYVAIGQKASSVASIVRKLEEHGALEHTIVVVAGASDSAALQY
IAPYAGCTMGEYFMERGEDALIVYDDLTKQAWAYRQISLLLRRPPGREAYPGDIFYLHSRLLERAARINADEVEKLTNGE
VKGKTGSLTALPIIETQAGDVSAFVPTNVISITDGQIFLDVDLFNSGVRPAINSGLSVSRVGGAAQTKIMKKLGGGTRLA
LAQFRELEAFSQFASDLDDATRKQLERGQRITELMKQKQYSPLTVAEMGVSLFVVEKGYLDDVPVNEISSFEASLHDYMR
STHAALLHAINEAGAYDNEIEAKLKKAVEEFKNTGSW

Sequences:

>Translated_517_residues
MSEQVALNPSEISELIRKKIDQFSVVSEARNEGTIVSLKDGIVRLHGLADVMAGEMIEFPGGVYGLALNLKRDSVGAVIL
GDSSTLAEGQKGKCTGRILEVPVGKGLLGRVVDALGNPIDGKGPIESSGMSPIEKVAPGVVTRKSIDQPVQTGLKAIDAM
IPVGRGQRELIIGDRQTGKTAIAIDAIINQKGTGVKCVYVAIGQKASSVASIVRKLEEHGALEHTIVVVAGASDSAALQY
IAPYAGCTMGEYFMERGEDALIVYDDLTKQAWAYRQISLLLRRPPGREAYPGDIFYLHSRLLERAARINADEVEKLTNGE
VKGKTGSLTALPIIETQAGDVSAFVPTNVISITDGQIFLDVDLFNSGVRPAINSGLSVSRVGGAAQTKIMKKLGGGTRLA
LAQFRELEAFSQFASDLDDATRKQLERGQRITELMKQKQYSPLTVAEMGVSLFVVEKGYLDDVPVNEISSFEASLHDYMR
STHAALLHAINEAGAYDNEIEAKLKKAVEEFKNTGSW
>Mature_516_residues
SEQVALNPSEISELIRKKIDQFSVVSEARNEGTIVSLKDGIVRLHGLADVMAGEMIEFPGGVYGLALNLKRDSVGAVILG
DSSTLAEGQKGKCTGRILEVPVGKGLLGRVVDALGNPIDGKGPIESSGMSPIEKVAPGVVTRKSIDQPVQTGLKAIDAMI
PVGRGQRELIIGDRQTGKTAIAIDAIINQKGTGVKCVYVAIGQKASSVASIVRKLEEHGALEHTIVVVAGASDSAALQYI
APYAGCTMGEYFMERGEDALIVYDDLTKQAWAYRQISLLLRRPPGREAYPGDIFYLHSRLLERAARINADEVEKLTNGEV
KGKTGSLTALPIIETQAGDVSAFVPTNVISITDGQIFLDVDLFNSGVRPAINSGLSVSRVGGAAQTKIMKKLGGGTRLAL
AQFRELEAFSQFASDLDDATRKQLERGQRITELMKQKQYSPLTVAEMGVSLFVVEKGYLDDVPVNEISSFEASLHDYMRS
THAALLHAINEAGAYDNEIEAKLKKAVEEFKNTGSW

Specific function: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit [H]

COG id: COG0056

COG function: function code C; F0F1-type ATP synthase, alpha subunit

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATPase alpha/beta chains family [H]

Homologues:

Organism=Homo sapiens, GI50345984, Length=510, Percent_Identity=55.4901960784314, Blast_Score=558, Evalue=1e-159,
Organism=Homo sapiens, GI4757810, Length=510, Percent_Identity=55.4901960784314, Blast_Score=558, Evalue=1e-159,
Organism=Homo sapiens, GI19913428, Length=335, Percent_Identity=27.1641791044776, Blast_Score=116, Evalue=7e-26,
Organism=Homo sapiens, GI19913426, Length=322, Percent_Identity=26.7080745341615, Blast_Score=112, Evalue=9e-25,
Organism=Homo sapiens, GI32189394, Length=457, Percent_Identity=23.1947483588621, Blast_Score=98, Evalue=2e-20,
Organism=Homo sapiens, GI19913424, Length=263, Percent_Identity=26.2357414448669, Blast_Score=72, Evalue=9e-13,
Organism=Escherichia coli, GI1790172, Length=511, Percent_Identity=72.6027397260274, Blast_Score=790, Evalue=0.0,
Organism=Escherichia coli, GI1790170, Length=310, Percent_Identity=25.1612903225806, Blast_Score=99, Evalue=9e-22,
Organism=Escherichia coli, GI1788251, Length=295, Percent_Identity=27.7966101694915, Blast_Score=96, Evalue=4e-21,
Organism=Caenorhabditis elegans, GI71988063, Length=513, Percent_Identity=55.7504873294347, Blast_Score=563, Evalue=1e-161,
Organism=Caenorhabditis elegans, GI71988080, Length=513, Percent_Identity=55.7504873294347, Blast_Score=562, Evalue=1e-160,
Organism=Caenorhabditis elegans, GI71988074, Length=513, Percent_Identity=51.8518518518518, Blast_Score=511, Evalue=1e-145,
Organism=Caenorhabditis elegans, GI17570191, Length=327, Percent_Identity=28.1345565749235, Blast_Score=122, Evalue=5e-28,
Organism=Caenorhabditis elegans, GI17510931, Length=377, Percent_Identity=26.2599469496021, Blast_Score=120, Evalue=1e-27,
Organism=Caenorhabditis elegans, GI25144756, Length=395, Percent_Identity=23.0379746835443, Blast_Score=91, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI17509265, Length=50, Percent_Identity=54, Blast_Score=69, Evalue=5e-12,
Organism=Caenorhabditis elegans, GI17565854, Length=258, Percent_Identity=26.3565891472868, Blast_Score=67, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6319370, Length=515, Percent_Identity=53.7864077669903, Blast_Score=565, Evalue=1e-162,
Organism=Saccharomyces cerevisiae, GI6319603, Length=409, Percent_Identity=27.3838630806846, Blast_Score=126, Evalue=6e-30,
Organism=Saccharomyces cerevisiae, GI6322581, Length=433, Percent_Identity=24.7113163972286, Blast_Score=107, Evalue=4e-24,
Organism=Drosophila melanogaster, GI24658560, Length=513, Percent_Identity=53.411306042885, Blast_Score=549, Evalue=1e-156,
Organism=Drosophila melanogaster, GI281361666, Length=364, Percent_Identity=26.6483516483516, Blast_Score=127, Evalue=3e-29,
Organism=Drosophila melanogaster, GI24646341, Length=364, Percent_Identity=26.6483516483516, Blast_Score=127, Evalue=3e-29,
Organism=Drosophila melanogaster, GI17136796, Length=364, Percent_Identity=26.6483516483516, Blast_Score=127, Evalue=3e-29,
Organism=Drosophila melanogaster, GI24638766, Length=331, Percent_Identity=25.0755287009063, Blast_Score=97, Evalue=4e-20,
Organism=Drosophila melanogaster, GI28574560, Length=323, Percent_Identity=25.3869969040248, Blast_Score=86, Evalue=7e-17,
Organism=Drosophila melanogaster, GI24583988, Length=263, Percent_Identity=26.615969581749, Blast_Score=72, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24583986, Length=263, Percent_Identity=26.615969581749, Blast_Score=72, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24583984, Length=263, Percent_Identity=26.615969581749, Blast_Score=72, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24583992, Length=263, Percent_Identity=26.615969581749, Blast_Score=71, Evalue=1e-12,

Paralogues:

None

Copy number: 9,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020003
- InterPro:   IPR000194
- InterPro:   IPR005294
- InterPro:   IPR017458
- InterPro:   IPR018118
- InterPro:   IPR000793
- InterPro:   IPR004100 [H]

Pfam domain/function: PF00006 ATP-synt_ab; PF00306 ATP-synt_ab_C; PF02874 ATP-synt_ab_N [H]

EC number: =3.6.3.14 [H]

Molecular weight: Translated: 55512; Mature: 55381

Theoretical pI: Translated: 5.78; Mature: 5.78

Prosite motif: PS00687 ALDEHYDE_DEHYDR_GLU ; PS00152 ATPASE_ALPHA_BETA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSEQVALNPSEISELIRKKIDQFSVVSEARNEGTIVSLKDGIVRLHGLADVMAGEMIEFP
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCHHHHHHHHHHHHCCHHHCC
GGVYGLALNLKRDSVGAVILGDSSTLAEGQKGKCTGRILEVPVGKGLLGRVVDALGNPID
CCEEEEEEEEECCCCCEEEECCCHHHCCCCCCCCCCEEEEECCCCCHHHHHHHHHCCCCC
GKGPIESSGMSPIEKVAPGVVTRKSIDQPVQTGLKAIDAMIPVGRGQRELIIGDRQTGKT
CCCCCCCCCCCHHHHHCCCCHHHHHCCHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCE
AIAIDAIINQKGTGVKCVYVAIGQKASSVASIVRKLEEHGALEHTIVVVAGASDSAALQY
EEEEEEHHCCCCCCEEEEEEEECCCHHHHHHHHHHHHHCCCCEEEEEEEECCCCCHHHHH
IAPYAGCTMGEYFMERGEDALIVYDDLTKQAWAYRQISLLLRRPPGREAYPGDIFYLHSR
HHHHCCCHHHHHHHHCCCCEEEEEECHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHH
LLERAARINADEVEKLTNGEVKGKTGSLTALPIIETQAGDVSAFVPTNVISITDGQIFLD
HHHHHHHCCHHHHHHHCCCCCCCCCCCEEEEEEEECCCCCEEEECCCCEEEEECCEEEEE
VDLFNSGVRPAINSGLSVSRVGGAAQTKIMKKLGGGTRLALAQFRELEAFSQFASDLDDA
EECCCCCCCHHHHCCCEEHHCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHH
TRKQLERGQRITELMKQKQYSPLTVAEMGVSLFVVEKGYLDDVPVNEISSFEASLHDYMR
HHHHHHHHHHHHHHHHHHCCCCCCHHHCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHH
STHAALLHAINEAGAYDNEIEAKLKKAVEEFKNTGSW
HHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
SEQVALNPSEISELIRKKIDQFSVVSEARNEGTIVSLKDGIVRLHGLADVMAGEMIEFP
CCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCHHHHHHHHHHHHCCHHHCC
GGVYGLALNLKRDSVGAVILGDSSTLAEGQKGKCTGRILEVPVGKGLLGRVVDALGNPID
CCEEEEEEEEECCCCCEEEECCCHHHCCCCCCCCCCEEEEECCCCCHHHHHHHHHCCCCC
GKGPIESSGMSPIEKVAPGVVTRKSIDQPVQTGLKAIDAMIPVGRGQRELIIGDRQTGKT
CCCCCCCCCCCHHHHHCCCCHHHHHCCHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCE
AIAIDAIINQKGTGVKCVYVAIGQKASSVASIVRKLEEHGALEHTIVVVAGASDSAALQY
EEEEEEHHCCCCCCEEEEEEEECCCHHHHHHHHHHHHHCCCCEEEEEEEECCCCCHHHHH
IAPYAGCTMGEYFMERGEDALIVYDDLTKQAWAYRQISLLLRRPPGREAYPGDIFYLHSR
HHHHCCCHHHHHHHHCCCCEEEEEECHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHH
LLERAARINADEVEKLTNGEVKGKTGSLTALPIIETQAGDVSAFVPTNVISITDGQIFLD
HHHHHHHCCHHHHHHHCCCCCCCCCCCEEEEEEEECCCCCEEEECCCCEEEEECCEEEEE
VDLFNSGVRPAINSGLSVSRVGGAAQTKIMKKLGGGTRLALAQFRELEAFSQFASDLDDA
EECCCCCCCHHHHCCCEEHHCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHH
TRKQLERGQRITELMKQKQYSPLTVAEMGVSLFVVEKGYLDDVPVNEISSFEASLHDYMR
HHHHHHHHHHHHHHHHHHCCCCCCHHHCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHH
STHAALLHAINEAGAYDNEIEAKLKKAVEEFKNTGSW
HHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA