| Definition | Legionella pneumophila str. Corby chromosome, complete genome. |
|---|---|
| Accession | NC_009494 |
| Length | 3,576,470 |
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The map label for this gene is lpxB [H]
Identifier: 148361282
GI number: 148361282
Start: 3507610
End: 3508761
Strand: Reverse
Name: lpxB [H]
Synonym: LPC_3256
Alternate gene names: 148361282
Gene position: 3508761-3507610 (Counterclockwise)
Preceding gene: 148361283
Following gene: 148361278
Centisome position: 98.11
GC content: 39.58
Gene sequence:
>1152_bases ATGAAAAGACCGACCCGAATTGCGATGGTTGCCGGCGAACTATCTGGAGACTTACTGGGAGCAGGGGTAATTCGTGAGCT GAAACAGCATTTAACAAACGTAGAATTCATGGGTGTCGGTGGTCCTCAAATGCTCAAGGAAGGTTTCCACTCCCTGATTG ATATCTCCGAGCTTTCTGTGATGGGAATCAGTGATGTTCTGAGACGATATCCTCAACTGTATTTAATAAGAGAAAGGTTA TTGAGGGAATGGACAATTAATCCACCAGATGTATTCATTGGGATTGATTACCCTGACTTTAATTTATCCGTTGAAGCACG GTTAAAAAAACAACATATTAAAACCATTCATCTGGTGAGCCCCAAAGTTTGGGCATGGCGACAAAAAAGGGTGCATTTAA TAAAAAAGGCAGTTGATTTAGTATTAACCCTATTTCCATTTGAAGAAGCATTTTACCGACAACATGGGGTATCTGCACAA TTTATTGGTCATCCTTTGGCTGATTTAATCGAAATAAACCCAAGTTGTTCTGTTTTACGTAAAAAATATAACTACCATTC TGATGATACCATTCTGGCAGTATTACCGGGTAGTCGAGTAGGTGAAATCAAATACATGGGGCCCTTGTTTTTGGAAGTAA TGCAAAGAATTGCTGTGGAGAGGCCTCATGTGCATTTCATAGTACCGATTGCGTGTCAGGATTTGTATCCTGTTTTTTTT AAACAACTCCATGTCGAGTATGGCCACTTAAAAATTCAGATCATTCAAGGGAACGCTCGTGAGGCTATGGCTATCTCTGA CGTTGTTTTAACAAAATCCGGAACAGCAACACTTGAGGCGATGCTTTTAAAACGACCCATGGTGGTTGCCTTTAAGTGGG GTATACTTACTCATGCGATTATCGCGCCTCAAGTAAAAGTTCCCTATATTGCGTTGCCTAATTTATTGGCTGGTAAAAAA TTAATCCCTGAATTTGTTCAGGAAAAAGCGAATGTTGATAGCATTAAAGAATCAGTTCTGAATTTACTCGACTCATCCAA TCAAAACGAACTAATTAAACAATTTACTGATATTCACTGCACATTAAGGCAAAATGCTAATGAGAAAGCGGCTTTAGCTA TCCTCAGGATTTTGGGGACTTCTTTGGCTTAA
Upstream 100 bases:
>100_bases TTGGCAATCTGAGCGTTTGCGGGATTAATACTGCTTGGCTATGGTTATTGGTTTAGGCTAACATCGAGTCATTTAAATTT TATATTGGTGCAATTTGACT
Downstream 100 bases:
>100_bases TCGCTGTTTTTAAAAATCGGATTTGTTTTTGCCAATCACTAATTGATACTGCTGGGTGGCCGCCGACCCTGTCTCCAGGT TTTACATCTTTGTAGACCAC
Product: lipid A-disaccharide synthase
Products: NA
Alternate protein names: NA
Number of amino acids: Translated: 383; Mature: 383
Protein sequence:
>383_residues MKRPTRIAMVAGELSGDLLGAGVIRELKQHLTNVEFMGVGGPQMLKEGFHSLIDISELSVMGISDVLRRYPQLYLIRERL LREWTINPPDVFIGIDYPDFNLSVEARLKKQHIKTIHLVSPKVWAWRQKRVHLIKKAVDLVLTLFPFEEAFYRQHGVSAQ FIGHPLADLIEINPSCSVLRKKYNYHSDDTILAVLPGSRVGEIKYMGPLFLEVMQRIAVERPHVHFIVPIACQDLYPVFF KQLHVEYGHLKIQIIQGNAREAMAISDVVLTKSGTATLEAMLLKRPMVVAFKWGILTHAIIAPQVKVPYIALPNLLAGKK LIPEFVQEKANVDSIKESVLNLLDSSNQNELIKQFTDIHCTLRQNANEKAALAILRILGTSLA
Sequences:
>Translated_383_residues MKRPTRIAMVAGELSGDLLGAGVIRELKQHLTNVEFMGVGGPQMLKEGFHSLIDISELSVMGISDVLRRYPQLYLIRERL LREWTINPPDVFIGIDYPDFNLSVEARLKKQHIKTIHLVSPKVWAWRQKRVHLIKKAVDLVLTLFPFEEAFYRQHGVSAQ FIGHPLADLIEINPSCSVLRKKYNYHSDDTILAVLPGSRVGEIKYMGPLFLEVMQRIAVERPHVHFIVPIACQDLYPVFF KQLHVEYGHLKIQIIQGNAREAMAISDVVLTKSGTATLEAMLLKRPMVVAFKWGILTHAIIAPQVKVPYIALPNLLAGKK LIPEFVQEKANVDSIKESVLNLLDSSNQNELIKQFTDIHCTLRQNANEKAALAILRILGTSLA >Mature_383_residues MKRPTRIAMVAGELSGDLLGAGVIRELKQHLTNVEFMGVGGPQMLKEGFHSLIDISELSVMGISDVLRRYPQLYLIRERL LREWTINPPDVFIGIDYPDFNLSVEARLKKQHIKTIHLVSPKVWAWRQKRVHLIKKAVDLVLTLFPFEEAFYRQHGVSAQ FIGHPLADLIEINPSCSVLRKKYNYHSDDTILAVLPGSRVGEIKYMGPLFLEVMQRIAVERPHVHFIVPIACQDLYPVFF KQLHVEYGHLKIQIIQGNAREAMAISDVVLTKSGTATLEAMLLKRPMVVAFKWGILTHAIIAPQVKVPYIALPNLLAGKK LIPEFVQEKANVDSIKESVLNLLDSSNQNELIKQFTDIHCTLRQNANEKAALAILRILGTSLA
Specific function: Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell [H]
COG id: COG0763
COG function: function code M; Lipid A disaccharide synthetase
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the lpxB family [H]
Homologues:
Organism=Escherichia coli, GI1786379, Length=378, Percent_Identity=42.5925925925926, Blast_Score=298, Evalue=5e-82,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR003835 [H]
Pfam domain/function: PF02684 LpxB [H]
EC number: =2.4.1.182 [H]
Molecular weight: Translated: 43252; Mature: 43252
Theoretical pI: Translated: 9.65; Mature: 9.65
Prosite motif: NA
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.8 %Cys (Translated Protein) 2.6 %Met (Translated Protein) 3.4 %Cys+Met (Translated Protein) 0.8 %Cys (Mature Protein) 2.6 %Met (Mature Protein) 3.4 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MKRPTRIAMVAGELSGDLLGAGVIRELKQHLTNVEFMGVGGPQMLKEGFHSLIDISELSV CCCCCEEEEEECCCCCCHHHHHHHHHHHHHHCCEEEEECCCHHHHHHHHHHHHHHHHHHH MGISDVLRRYPQLYLIRERLLREWTINPPDVFIGIDYPDFNLSVEARLKKQHIKTIHLVS CCHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCCHHHHHHHHHCCEEEEEC PKVWAWRQKRVHLIKKAVDLVLTLFPFEEAFYRQHGVSAQFIGHPLADLIEINPSCSVLR CCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCHHHHCCCHHHHHCCCCCHHHHH KKYNYHSDDTILAVLPGSRVGEIKYMGPLFLEVMQRIAVERPHVHFIVPIACQDLYPVFF HHCCCCCCCEEEEEECCCCCCCEEECCHHHHHHHHHHHCCCCCEEEEEEEHHHHHHHHHH KQLHVEYGHLKIQIIQGNAREAMAISDVVLTKSGTATLEAMLLKRPMVVAFKWGILTHAI HHHHHEECEEEEEEEECCCCCHHHHHHEEEECCCCHHHHHHHHCCCCCEEEEHHHHHHHH IAPQVKVPYIALPNLLAGKKLIPEFVQEKANVDSIKESVLNLLDSSNQNELIKQFTDIHC HCCCCCCCEEECCCHHCCHHHHHHHHHHHCCHHHHHHHHHHHHCCCCHHHHHHHHHHHEE TLRQNANEKAALAILRILGTSLA EECCCCCHHHHHHHHHHHHHCCC >Mature Secondary Structure MKRPTRIAMVAGELSGDLLGAGVIRELKQHLTNVEFMGVGGPQMLKEGFHSLIDISELSV CCCCCEEEEEECCCCCCHHHHHHHHHHHHHHCCEEEEECCCHHHHHHHHHHHHHHHHHHH MGISDVLRRYPQLYLIRERLLREWTINPPDVFIGIDYPDFNLSVEARLKKQHIKTIHLVS CCHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCCHHHHHHHHHCCEEEEEC PKVWAWRQKRVHLIKKAVDLVLTLFPFEEAFYRQHGVSAQFIGHPLADLIEINPSCSVLR CCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCHHHHCCCHHHHHCCCCCHHHHH KKYNYHSDDTILAVLPGSRVGEIKYMGPLFLEVMQRIAVERPHVHFIVPIACQDLYPVFF HHCCCCCCCEEEEEECCCCCCCEEECCHHHHHHHHHHHCCCCCEEEEEEEHHHHHHHHHH KQLHVEYGHLKIQIIQGNAREAMAISDVVLTKSGTATLEAMLLKRPMVVAFKWGILTHAI HHHHHEECEEEEEEEECCCCCHHHHHHEEEECCCCHHHHHHHHCCCCCEEEEHHHHHHHH IAPQVKVPYIALPNLLAGKKLIPEFVQEKANVDSIKESVLNLLDSSNQNELIKQFTDIHC HCCCCCCCEEECCCHHCCHHHHHHHHHHHCCHHHHHHHHHHHHCCCCHHHHHHHHHHHEE TLRQNANEKAALAILRILGTSLA EECCCCCHHHHHHHHHHHHHCCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 9.0
TargetDB status: NA
Availability: NA
References: NA