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The map label for this gene is lrsB [C]

Identifier: 148361188

GI number: 148361188

Start: 3422540

End: 3423781

Strand: Direct

Name: lrsB [C]

Synonym: LPC_3162

Alternate gene names: 148361188

Gene position: 3422540-3423781 (Clockwise)

Preceding gene: 148361187

Following gene: 148361190

Centisome position: 95.7

GC content: 36.96

Gene sequence:

>1242_bases
ATGCCTTCTGCTGTCATCATTCTTCTGATTATCCTTATTGCGATTGCTTTACGCCAGGTTGTTAGAGTTGTCATTCCAAT
TTGGGCAATTATGGCAACAGGAGCCATTGCTGTTTTGCTCTGCCAACAGATAACTCCATCACGCGCTTTTACTGCCGTTG
AGCCGGATGTCATGCTTTATTTGTTTGGTGTTTTTTTCATTTCACAAGCCGCAGAGGAAAGTGGCTACCTTGCTTTTCTG
ACTGATCAAATTTTTTATTATGCGAATAATGGAAAACAAACGTTAATGTTGATTGTTTTCATTCTGGGTTTAAGCTCCGC
GGTGTTAATGAATGATACCATTGCCATTATAGGTACACCTATCATTTTACAACTGTGTCAATCACATAAAAATTTAATTA
AACCCTTGCTGTTGGCATTGGCATTTTCAATTACTATTGGAAGCACCATGAGTCCTATAGGCAATCCACAAAATTTATTG
ATTGCTATTAAGGGAGAGATGGCCTCGCCATTTTTTGAGTTTTTCAAACACCTGGCCGTACCTACTTTGTTAAATCTGTT
TATAGTTTATTTTTTTATTCTTTTTTTATATAAAAATGAATTAAAAGAACCTATTAAAAAACCAGTCCTCCCCTTGATAA
GTGACCGTAGCAATCTTACTTTGGTTAAAATGAGCTTGCTCATGATGTTAGTTCTGACTGTGATCAAAATCTTGACGGAT
TTCCTGCATTATTCAGAATTTCAGCTGAATTTTAGTTATATTGCACTCTTGTCGTCTGCACCAATTTGGTTTAGCAAGCA
TCGATGGAAATATATAAAAAGACTGGATTGGGGAACTTTAGTTTTTTTTGCGAGCACCTTTATTTTAATGCAAAGCGTAT
GGGATAGCGGTTTTTTCCAAACCGGAATGAGTGATTCTCATATTGATGTCAGCCGCATCGTGGTGATTTTTATAATGAGT
ATCGCCCTGAGCCAATTGATCTCTAATGTCCCATTAGTAACAATATATTTGCCTTTATTGATGAGTCATAATCATTCCAG
TATAACCCTGCTGAGCCTGGCTGCGGGAAGTACTATTGCCGGGAATCTCTCTATCCTGGGGGCAGCAAGTAATATTATTA
TTATTCAAAATAGTGAAAAACGTGGTATCAGAGGTTTTGGATTTCTGGAGTTTATACTTGTGGGAGCCCCACTTACCTTA
CTCAATCTATTAGTGTATATCTCATTCCTTCAAAAAATATAA

Upstream 100 bases:

>100_bases
CCGCCCGATGAGTTAACATTAACCGAATCACGACAAAAAACCATCTACGGCTGGAAAAGGCCGGTAAAAAGGGAGAGGGA
TTAAATAAAAGAGGACAGAA

Downstream 100 bases:

>100_bases
GAGAATGAACCATTAAATTTGTTTATTTAATTCCTCTCTGTTTGCACAACTAATGAATAATTTCTTTCTAAAATCTTGCA
CATCCATAAAATGACCGGGA

Product: arsenite efflux protein ArsB

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 413; Mature: 412

Protein sequence:

>413_residues
MPSAVIILLIILIAIALRQVVRVVIPIWAIMATGAIAVLLCQQITPSRAFTAVEPDVMLYLFGVFFISQAAEESGYLAFL
TDQIFYYANNGKQTLMLIVFILGLSSAVLMNDTIAIIGTPIILQLCQSHKNLIKPLLLALAFSITIGSTMSPIGNPQNLL
IAIKGEMASPFFEFFKHLAVPTLLNLFIVYFFILFLYKNELKEPIKKPVLPLISDRSNLTLVKMSLLMMLVLTVIKILTD
FLHYSEFQLNFSYIALLSSAPIWFSKHRWKYIKRLDWGTLVFFASTFILMQSVWDSGFFQTGMSDSHIDVSRIVVIFIMS
IALSQLISNVPLVTIYLPLLMSHNHSSITLLSLAAGSTIAGNLSILGAASNIIIIQNSEKRGIRGFGFLEFILVGAPLTL
LNLLVYISFLQKI

Sequences:

>Translated_413_residues
MPSAVIILLIILIAIALRQVVRVVIPIWAIMATGAIAVLLCQQITPSRAFTAVEPDVMLYLFGVFFISQAAEESGYLAFL
TDQIFYYANNGKQTLMLIVFILGLSSAVLMNDTIAIIGTPIILQLCQSHKNLIKPLLLALAFSITIGSTMSPIGNPQNLL
IAIKGEMASPFFEFFKHLAVPTLLNLFIVYFFILFLYKNELKEPIKKPVLPLISDRSNLTLVKMSLLMMLVLTVIKILTD
FLHYSEFQLNFSYIALLSSAPIWFSKHRWKYIKRLDWGTLVFFASTFILMQSVWDSGFFQTGMSDSHIDVSRIVVIFIMS
IALSQLISNVPLVTIYLPLLMSHNHSSITLLSLAAGSTIAGNLSILGAASNIIIIQNSEKRGIRGFGFLEFILVGAPLTL
LNLLVYISFLQKI
>Mature_412_residues
PSAVIILLIILIAIALRQVVRVVIPIWAIMATGAIAVLLCQQITPSRAFTAVEPDVMLYLFGVFFISQAAEESGYLAFLT
DQIFYYANNGKQTLMLIVFILGLSSAVLMNDTIAIIGTPIILQLCQSHKNLIKPLLLALAFSITIGSTMSPIGNPQNLLI
AIKGEMASPFFEFFKHLAVPTLLNLFIVYFFILFLYKNELKEPIKKPVLPLISDRSNLTLVKMSLLMMLVLTVIKILTDF
LHYSEFQLNFSYIALLSSAPIWFSKHRWKYIKRLDWGTLVFFASTFILMQSVWDSGFFQTGMSDSHIDVSRIVVIFIMSI
ALSQLISNVPLVTIYLPLLMSHNHSSITLLSLAAGSTIAGNLSILGAASNIIIIQNSEKRGIRGFGFLEFILVGAPLTLL
NLLVYISFLQKI

Specific function: Unknown

COG id: COG1055

COG function: function code P; Na+/H+ antiporter NhaD and related arsenite permeases

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CitM (TC 2.A.11) transporter family [H]

Homologues:

Organism=Homo sapiens, GI157266326, Length=447, Percent_Identity=23.2662192393736, Blast_Score=83, Evalue=4e-16,
Organism=Drosophila melanogaster, GI19920704, Length=157, Percent_Identity=27.3885350318471, Blast_Score=66, Evalue=4e-11,
Organism=Drosophila melanogaster, GI28574683, Length=156, Percent_Identity=27.5641025641026, Blast_Score=66, Evalue=4e-11,
Organism=Drosophila melanogaster, GI28574681, Length=156, Percent_Identity=27.5641025641026, Blast_Score=66, Evalue=4e-11,
Organism=Drosophila melanogaster, GI28574685, Length=156, Percent_Identity=27.5641025641026, Blast_Score=66, Evalue=4e-11,
Organism=Drosophila melanogaster, GI28574678, Length=156, Percent_Identity=27.5641025641026, Blast_Score=66, Evalue=4e-11,
Organism=Drosophila melanogaster, GI24581759, Length=156, Percent_Identity=27.5641025641026, Blast_Score=66, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000802
- InterPro:   IPR004680 [H]

Pfam domain/function: PF03600 CitMHS [H]

EC number: NA

Molecular weight: Translated: 45962; Mature: 45831

Theoretical pI: Translated: 9.55; Mature: 9.55

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPSAVIILLIILIAIALRQVVRVVIPIWAIMATGAIAVLLCQQITPSRAFTAVEPDVMLY
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEECCHHHHHH
LFGVFFISQAAEESGYLAFLTDQIFYYANNGKQTLMLIVFILGLSSAVLMNDTIAIIGTP
HHHHHHHHHHHHCCCCEEEEEEEEEEEECCCCHHHHHHHHHHHCCCHHHHCCCHHHHHHH
IILQLCQSHKNLIKPLLLALAFSITIGSTMSPIGNPQNLLIAIKGEMASPFFEFFKHLAV
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEEECCCCCHHHHHHHHHHH
PTLLNLFIVYFFILFLYKNELKEPIKKPVLPLISDRSNLTLVKMSLLMMLVLTVIKILTD
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCCCCCHHHHHHHHHHHHHHHHHHHHH
FLHYSEFQLNFSYIALLSSAPIWFSKHRWKYIKRLDWGTLVFFASTFILMQSVWDSGFFQ
HHHHHHHEECHHHHHHHHCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCC
TGMSDSHIDVSRIVVIFIMSIALSQLISNVPLVTIYLPLLMSHNHSSITLLSLAAGSTIA
CCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCEEEEEEECCCCEE
GNLSILGAASNIIIIQNSEKRGIRGFGFLEFILVGAPLTLLNLLVYISFLQKI
CCEEEEECCCCEEEEECCCCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHC
>Mature Secondary Structure 
PSAVIILLIILIAIALRQVVRVVIPIWAIMATGAIAVLLCQQITPSRAFTAVEPDVMLY
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEECCHHHHHH
LFGVFFISQAAEESGYLAFLTDQIFYYANNGKQTLMLIVFILGLSSAVLMNDTIAIIGTP
HHHHHHHHHHHHCCCCEEEEEEEEEEEECCCCHHHHHHHHHHHCCCHHHHCCCHHHHHHH
IILQLCQSHKNLIKPLLLALAFSITIGSTMSPIGNPQNLLIAIKGEMASPFFEFFKHLAV
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEEECCCCCHHHHHHHHHHH
PTLLNLFIVYFFILFLYKNELKEPIKKPVLPLISDRSNLTLVKMSLLMMLVLTVIKILTD
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCCCCCHHHHHHHHHHHHHHHHHHHHH
FLHYSEFQLNFSYIALLSSAPIWFSKHRWKYIKRLDWGTLVFFASTFILMQSVWDSGFFQ
HHHHHHHEECHHHHHHHHCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCC
TGMSDSHIDVSRIVVIFIMSIALSQLISNVPLVTIYLPLLMSHNHSSITLLSLAAGSTIA
CCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCEEEEEEECCCCEE
GNLSILGAASNIIIIQNSEKRGIRGFGFLEFILVGAPLTLLNLLVYISFLQKI
CCEEEEECCCCEEEEECCCCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]