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The map label for this gene is prkA [H]

Identifier: 148361122

GI number: 148361122

Start: 3345794

End: 3347725

Strand: Direct

Name: prkA [H]

Synonym: LPC_3096

Alternate gene names: 148361122

Gene position: 3345794-3347725 (Clockwise)

Preceding gene: 148361119

Following gene: 148361123

Centisome position: 93.55

GC content: 40.01

Gene sequence:

>1932_bases
ATGAATACACAAGATTTTTTAGCGGGTTATACCAAACGATTTGTTGATAACAAAGAAGAAGACATGAGTTTGGATGAATA
TCTGGAGTTGTGCAAAACGGACCCGACAGCATATGCCAACCCAGCAGAACGTTTGCTTATGGCGATAGGCGAGCCTGAAT
TGATCGACACCCGACATGATCCGGTTCTATCACGAATTTTCTCAAATAAAATAATCCATCATTATGAAGTTTTTAAAGAT
TTTTATGGAATGGAAGAGCCTATTGAGCAAATCGTTGGCTTTTTGAAGCATGCTGCGCAAGGGTTAGAGGAAACAAAACA
GGTTTTGTATCTTTTGGGGCCTGTTGGCGGTGGTAAATCTTCCATTGCAGAAAAATTGAAAGATTTAATGGAAAGAATCC
CTTTTTATGCAATCAAAGGTTCTCCTGTCTTTGAATCTCCACTGTCATTATTTAACCCCTTGGAAGATGGTGAATTGCTT
AGAGAACGTTTTGGTATCCCAACACGCTACCTACGCTACTTAATGTCTCCCTGGGCAGTCAAACGATTACAGGAATACAA
TGGCGACATCAGCAAATTCCGGGTTATTAAAGTCAAGCCTTCTCGACTCAAACAAATTGCCATCGCAAAAACAGAACCTG
GCGATGAAAACAATCAAGATATTTCTTCTCTGGTTGGTAAAGTCGATATCCGTAAATTGGAAGAATTTTCCCAAGATGAT
CCTGATGCTTACAGCTACTCTGGAGGCTTGTGTCGAGCCAACCGCGGGCTTTTGGAGTTCGTTGAAATGTTTAAGGCACC
GATAAAGGTCCTTCATCCCTTGCTGACTGCAACGCAAGAAGGGAATTACAATGCCACAGAAGGGCTTTCAGCTATTCCTT
TTGAAGGAATTATACTAGCCCACTCCAATGAATCAGAATGGCAATCATTTAGAAACAATAAAAATAACGAGGCATTTATA
GACCGAATCAACATAGTCAAAGTGCCTTATTGCCTGCGCGTTTCTGAAGAAATCAAAATCTACCAAAAACTAATCCATAA
CAGTTCTTTAGCCAATGCCCCTTGCGCACCTGGTACACTGGATATGCTAGCCCAGTTTTCTGTATTAACCCGTTTAAAAG
AACCACAAAACTCCAGCATTTACTCCAAAATGCGCGTGTATAATGGAGAGAGTTTGAAAGATACCGATCCCAAGGCAAAA
TCGTATCAGGAGTATAGAGATTTTGCAGGAGTTGACGAAGGGATGAGCGGAATATCCACACGGTTTGCCTTCAAAATCCT
TTCAAAAGTATTCAATTTTGATCATACTGAAGTGGCAGCCAACCCGGTTCATTTAATGTATGTGCTGGAACGCCAAATCG
AACAGGAACAATTTCCTCAAGAGTTACATGAAACCTACTTGAACTTCATTAAAGAATATTTGGCGACCAAATACGTCGAT
TTTATAGGCAAGGAAATTCAAACCGCTTACCTGGAATCCTATTCTGAGTATGGGCAGAACATATTTGACCGTTACATTAC
CTATGCTGATTTCTGGATTCAAGATCAGGATTATCGCGATCCGGATACTGGGGAGATATTTGACAGAGCCTTATTAAACC
TGGAATTGGAGAAAATCGAAAAACCGGCAGGGATCTCCAATCCTAAAGACTTCCGTAATGAAGTAGTCAATTTCGTATTG
CGTGCTCGAGCAAATAACCGAGGAAAAAACCCTGTATGGAATAGCTATGAAAAACTAAAATCAGTGATTGAGAAAAAAAT
GTTTACCAATACGGAAGATTTGTTACCCGTTATTTCTTTCAATGCCAAAGCATCTGAGGAAGATAAGAAAAAACATGAAG
AGTTTATCTCTCGAATGGTAGAGAAAGGCTACACACGAAAACAAGTTCGCTTACTTTGTGAATGGTATTTGAGAGTAAGG
AAGTCACAATAA

Upstream 100 bases:

>100_bases
TACTATGAATTAAAAGAAGTAATTTTTGCTTTTATACAGGAAAGAGTAAAAAAAGAATCACATTATATCCTTCTCAGGGT
TAAGTAAAAGGGGATGGCGC

Downstream 100 bases:

>100_bases
TAGGTAGGATAATTCATAACTCGATAGGTTATGAAATACAGTCAGGGTTGTAAGTAACTATCTGAAAATAATCAAGTAGA
ATCCTAAATTCAGATACTGC

Product: serine protein kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 643; Mature: 643

Protein sequence:

>643_residues
MNTQDFLAGYTKRFVDNKEEDMSLDEYLELCKTDPTAYANPAERLLMAIGEPELIDTRHDPVLSRIFSNKIIHHYEVFKD
FYGMEEPIEQIVGFLKHAAQGLEETKQVLYLLGPVGGGKSSIAEKLKDLMERIPFYAIKGSPVFESPLSLFNPLEDGELL
RERFGIPTRYLRYLMSPWAVKRLQEYNGDISKFRVIKVKPSRLKQIAIAKTEPGDENNQDISSLVGKVDIRKLEEFSQDD
PDAYSYSGGLCRANRGLLEFVEMFKAPIKVLHPLLTATQEGNYNATEGLSAIPFEGIILAHSNESEWQSFRNNKNNEAFI
DRINIVKVPYCLRVSEEIKIYQKLIHNSSLANAPCAPGTLDMLAQFSVLTRLKEPQNSSIYSKMRVYNGESLKDTDPKAK
SYQEYRDFAGVDEGMSGISTRFAFKILSKVFNFDHTEVAANPVHLMYVLERQIEQEQFPQELHETYLNFIKEYLATKYVD
FIGKEIQTAYLESYSEYGQNIFDRYITYADFWIQDQDYRDPDTGEIFDRALLNLELEKIEKPAGISNPKDFRNEVVNFVL
RARANNRGKNPVWNSYEKLKSVIEKKMFTNTEDLLPVISFNAKASEEDKKKHEEFISRMVEKGYTRKQVRLLCEWYLRVR
KSQ

Sequences:

>Translated_643_residues
MNTQDFLAGYTKRFVDNKEEDMSLDEYLELCKTDPTAYANPAERLLMAIGEPELIDTRHDPVLSRIFSNKIIHHYEVFKD
FYGMEEPIEQIVGFLKHAAQGLEETKQVLYLLGPVGGGKSSIAEKLKDLMERIPFYAIKGSPVFESPLSLFNPLEDGELL
RERFGIPTRYLRYLMSPWAVKRLQEYNGDISKFRVIKVKPSRLKQIAIAKTEPGDENNQDISSLVGKVDIRKLEEFSQDD
PDAYSYSGGLCRANRGLLEFVEMFKAPIKVLHPLLTATQEGNYNATEGLSAIPFEGIILAHSNESEWQSFRNNKNNEAFI
DRINIVKVPYCLRVSEEIKIYQKLIHNSSLANAPCAPGTLDMLAQFSVLTRLKEPQNSSIYSKMRVYNGESLKDTDPKAK
SYQEYRDFAGVDEGMSGISTRFAFKILSKVFNFDHTEVAANPVHLMYVLERQIEQEQFPQELHETYLNFIKEYLATKYVD
FIGKEIQTAYLESYSEYGQNIFDRYITYADFWIQDQDYRDPDTGEIFDRALLNLELEKIEKPAGISNPKDFRNEVVNFVL
RARANNRGKNPVWNSYEKLKSVIEKKMFTNTEDLLPVISFNAKASEEDKKKHEEFISRMVEKGYTRKQVRLLCEWYLRVR
KSQ
>Mature_643_residues
MNTQDFLAGYTKRFVDNKEEDMSLDEYLELCKTDPTAYANPAERLLMAIGEPELIDTRHDPVLSRIFSNKIIHHYEVFKD
FYGMEEPIEQIVGFLKHAAQGLEETKQVLYLLGPVGGGKSSIAEKLKDLMERIPFYAIKGSPVFESPLSLFNPLEDGELL
RERFGIPTRYLRYLMSPWAVKRLQEYNGDISKFRVIKVKPSRLKQIAIAKTEPGDENNQDISSLVGKVDIRKLEEFSQDD
PDAYSYSGGLCRANRGLLEFVEMFKAPIKVLHPLLTATQEGNYNATEGLSAIPFEGIILAHSNESEWQSFRNNKNNEAFI
DRINIVKVPYCLRVSEEIKIYQKLIHNSSLANAPCAPGTLDMLAQFSVLTRLKEPQNSSIYSKMRVYNGESLKDTDPKAK
SYQEYRDFAGVDEGMSGISTRFAFKILSKVFNFDHTEVAANPVHLMYVLERQIEQEQFPQELHETYLNFIKEYLATKYVD
FIGKEIQTAYLESYSEYGQNIFDRYITYADFWIQDQDYRDPDTGEIFDRALLNLELEKIEKPAGISNPKDFRNEVVNFVL
RARANNRGKNPVWNSYEKLKSVIEKKMFTNTEDLLPVISFNAKASEEDKKKHEEFISRMVEKGYTRKQVRLLCEWYLRVR
KSQ

Specific function: Unknown

COG id: COG2766

COG function: function code T; Putative Ser protein kinase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the prkA family [H]

Homologues:

Organism=Escherichia coli, GI1788083, Length=637, Percent_Identity=74.7252747252747, Blast_Score=1023, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013153
- InterPro:   IPR010650
- InterPro:   IPR016230 [H]

Pfam domain/function: PF08298 AAA_PrkA; PF06798 PrkA [H]

EC number: NA

Molecular weight: Translated: 74345; Mature: 74345

Theoretical pI: Translated: 5.64; Mature: 5.64

Prosite motif: PS00107 PROTEIN_KINASE_ATP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNTQDFLAGYTKRFVDNKEEDMSLDEYLELCKTDPTAYANPAERLLMAIGEPELIDTRHD
CCCHHHHHHHHHHHHCCCHHCCCHHHHHHHHCCCCCCCCCHHHHHHHHCCCCCCCCCCCC
PVLSRIFSNKIIHHYEVFKDFYGMEEPIEQIVGFLKHAAQGLEETKQVLYLLGPVGGGKS
HHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHH
SIAEKLKDLMERIPFYAIKGSPVFESPLSLFNPLEDGELLRERFGIPTRYLRYLMSPWAV
HHHHHHHHHHHHCCEEEECCCCCHHCHHHHHCCCCCHHHHHHHHCCCHHHHHHHHCHHHH
KRLQEYNGDISKFRVIKVKPSRLKQIAIAKTEPGDENNQDISSLVGKVDIRKLEEFSQDD
HHHHHHCCCHHHEEEEEECHHHHHHHHEECCCCCCCCCHHHHHHHHHHHHHHHHHHCCCC
PDAYSYSGGLCRANRGLLEFVEMFKAPIKVLHPLLTATQEGNYNATEGLSAIPFEGIILA
CCCCCCCCCCHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHCCCCCCCCCCEEEE
HSNESEWQSFRNNKNNEAFIDRINIVKVPYCLRVSEEIKIYQKLIHNSSLANAPCAPGTL
CCCHHHHHHHHCCCCCHHHHHHHHEEECCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHH
DMLAQFSVLTRLKEPQNSSIYSKMRVYNGESLKDTDPKAKSYQEYRDFAGVDEGMSGIST
HHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHCCHHHHHHHHHH
RFAFKILSKVFNFDHTEVAANPVHLMYVLERQIEQEQFPQELHETYLNFIKEYLATKYVD
HHHHHHHHHHHCCCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FIGKEIQTAYLESYSEYGQNIFDRYITYADFWIQDQDYRDPDTGEIFDRALLNLELEKIE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCCCHHHHHHHHHHHHHHHHHC
KPAGISNPKDFRNEVVNFVLRARANNRGKNPVWNSYEKLKSVIEKKMFTNTEDLLPVISF
CCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHCC
NAKASEEDKKKHEEFISRMVEKGYTRKQVRLLCEWYLRVRKSQ
CCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MNTQDFLAGYTKRFVDNKEEDMSLDEYLELCKTDPTAYANPAERLLMAIGEPELIDTRHD
CCCHHHHHHHHHHHHCCCHHCCCHHHHHHHHCCCCCCCCCHHHHHHHHCCCCCCCCCCCC
PVLSRIFSNKIIHHYEVFKDFYGMEEPIEQIVGFLKHAAQGLEETKQVLYLLGPVGGGKS
HHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHH
SIAEKLKDLMERIPFYAIKGSPVFESPLSLFNPLEDGELLRERFGIPTRYLRYLMSPWAV
HHHHHHHHHHHHCCEEEECCCCCHHCHHHHHCCCCCHHHHHHHHCCCHHHHHHHHCHHHH
KRLQEYNGDISKFRVIKVKPSRLKQIAIAKTEPGDENNQDISSLVGKVDIRKLEEFSQDD
HHHHHHCCCHHHEEEEEECHHHHHHHHEECCCCCCCCCHHHHHHHHHHHHHHHHHHCCCC
PDAYSYSGGLCRANRGLLEFVEMFKAPIKVLHPLLTATQEGNYNATEGLSAIPFEGIILA
CCCCCCCCCCHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHCCCCCCCCCCEEEE
HSNESEWQSFRNNKNNEAFIDRINIVKVPYCLRVSEEIKIYQKLIHNSSLANAPCAPGTL
CCCHHHHHHHHCCCCCHHHHHHHHEEECCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHH
DMLAQFSVLTRLKEPQNSSIYSKMRVYNGESLKDTDPKAKSYQEYRDFAGVDEGMSGIST
HHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHCCHHHHHHHHHH
RFAFKILSKVFNFDHTEVAANPVHLMYVLERQIEQEQFPQELHETYLNFIKEYLATKYVD
HHHHHHHHHHHCCCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FIGKEIQTAYLESYSEYGQNIFDRYITYADFWIQDQDYRDPDTGEIFDRALLNLELEKIE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCCCHHHHHHHHHHHHHHHHHC
KPAGISNPKDFRNEVVNFVLRARANNRGKNPVWNSYEKLKSVIEKKMFTNTEDLLPVISF
CCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHCC
NAKASEEDKKKHEEFISRMVEKGYTRKQVRLLCEWYLRVRKSQ
CCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]