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The map label for this gene is pgl [H]

Identifier: 148360966

GI number: 148360966

Start: 508525

End: 509238

Strand: Direct

Name: pgl [H]

Synonym: LPC_2926

Alternate gene names: 148360966

Gene position: 508525-509238 (Clockwise)

Preceding gene: 148360967

Following gene: 148360965

Centisome position: 14.22

GC content: 42.02

Gene sequence:

>714_bases
ATGCAGTTTCATAGTTTTAGGGATGCCAAACAGTTGATTCATGACATGGTGGAAAAATTAAGAACTATTCTATCAGATGC
AATCAAACGAAGAGGGCAAGCTTTTTTGGTGGTTTCCGGCGGTAGAACCCCTATCGATTTGTTCAAGGAATTGGCTTTAG
CCGACTTGCCTTGGGAAAAAGTAGTGATCACTTTGGCCGATGAACGTTGTGTCAACCTTTTTGATCCACATCGTAACGAG
CTGCTGGTGCGTGAATTTCTGCTGCAAGAGAAGGCAAAAAAAGCCAAATTTATCAGCTTGTTTGATGAAAAAGAGGAGCC
ATTAGGTCATTTGAATGAGGTGAGTAGCCAAATTGACTCTCTACCAACATTTGATGCAGTAGTTTTAGGAATGGGTGAAG
ACGGCCATACTGCTTCTTTATTTCCATGCAGTGATGAGTTAAGTGCAGGATTAGATGATAAAGCAAATGCGGTGCTTATT
GTGAAGCCTAGAACAGCTTCATTCCAGAGGGTTAGCCTATCGAAAAGGCGATTATTAAACAGCAGTACTATTTTTTTACA
TTTAGTAGGTCAAAGAAAACGGGTTGTTCTGGAGCAGGCAATGGCAACTAACAACCCGGAGATCCTGCCAATCTGCGCTA
TTTTAAATGCCCCGGATGCCAATGTTCAGGTGATGTATGCTCCAAGCGATGAGGAAAAAGAATGCATCCTGTAA

Upstream 100 bases:

>100_bases
GAAGATAATATTCCGCTGTATACCTATCCAGCTTGTACCTGGGGGCCAAAGGAAGTCATACGCTTATTTAACGGGCAAGC
ACATGTTTGGGGTGATCACA

Downstream 100 bases:

>100_bases
TAAATCAAGTGACAGAAAATATCCAAAATCGTAGCGCTTCTAGAAGAGCAGCTTATCTGAATCAAATCGATAAGGCTCGT
ACTAAAGGCCCACAACGAAG

Product: 6-phosphogluconolactonase

Products: NA

Alternate protein names: 6PGL [H]

Number of amino acids: Translated: 237; Mature: 237

Protein sequence:

>237_residues
MQFHSFRDAKQLIHDMVEKLRTILSDAIKRRGQAFLVVSGGRTPIDLFKELALADLPWEKVVITLADERCVNLFDPHRNE
LLVREFLLQEKAKKAKFISLFDEKEEPLGHLNEVSSQIDSLPTFDAVVLGMGEDGHTASLFPCSDELSAGLDDKANAVLI
VKPRTASFQRVSLSKRRLLNSSTIFLHLVGQRKRVVLEQAMATNNPEILPICAILNAPDANVQVMYAPSDEEKECIL

Sequences:

>Translated_237_residues
MQFHSFRDAKQLIHDMVEKLRTILSDAIKRRGQAFLVVSGGRTPIDLFKELALADLPWEKVVITLADERCVNLFDPHRNE
LLVREFLLQEKAKKAKFISLFDEKEEPLGHLNEVSSQIDSLPTFDAVVLGMGEDGHTASLFPCSDELSAGLDDKANAVLI
VKPRTASFQRVSLSKRRLLNSSTIFLHLVGQRKRVVLEQAMATNNPEILPICAILNAPDANVQVMYAPSDEEKECIL
>Mature_237_residues
MQFHSFRDAKQLIHDMVEKLRTILSDAIKRRGQAFLVVSGGRTPIDLFKELALADLPWEKVVITLADERCVNLFDPHRNE
LLVREFLLQEKAKKAKFISLFDEKEEPLGHLNEVSSQIDSLPTFDAVVLGMGEDGHTASLFPCSDELSAGLDDKANAVLI
VKPRTASFQRVSLSKRRLLNSSTIFLHLVGQRKRVVLEQAMATNNPEILPICAILNAPDANVQVMYAPSDEEKECIL

Specific function: Hydrolysis of 6-phosphogluconolactone to 6- phosphogluconate [H]

COG id: COG0363

COG function: function code G; 6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. 6-phosphogluconolactonase subfamily [H]

Homologues:

Organism=Homo sapiens, GI52145310, Length=240, Percent_Identity=31.25, Blast_Score=94, Evalue=1e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005900 [H]

Pfam domain/function: NA

EC number: =3.1.1.31 [H]

Molecular weight: Translated: 26562; Mature: 26562

Theoretical pI: Translated: 5.97; Mature: 5.97

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQFHSFRDAKQLIHDMVEKLRTILSDAIKRRGQAFLVVSGGRTPIDLFKELALADLPWEK
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCHHHHHHHHHHCCCCHHH
VVITLADERCVNLFDPHRNELLVREFLLQEKAKKAKFISLFDEKEEPLGHLNEVSSQIDS
EEEEECCCHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHC
LPTFDAVVLGMGEDGHTASLFPCSDELSAGLDDKANAVLIVKPRTASFQRVSLSKRRLLN
CCCCCEEEEECCCCCCEEEEECCCHHHHCCCCCCCCEEEEECCCCCCHHHHHHHHHHHCC
SSTIFLHLVGQRKRVVLEQAMATNNPEILPICAILNAPDANVQVMYAPSDEEKECIL
CCEEEEEEECCHHHHHHHHHHHCCCCCEEEEEEEECCCCCCEEEEECCCCCCCCCCC
>Mature Secondary Structure
MQFHSFRDAKQLIHDMVEKLRTILSDAIKRRGQAFLVVSGGRTPIDLFKELALADLPWEK
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCHHHHHHHHHHCCCCHHH
VVITLADERCVNLFDPHRNELLVREFLLQEKAKKAKFISLFDEKEEPLGHLNEVSSQIDS
EEEEECCCHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHC
LPTFDAVVLGMGEDGHTASLFPCSDELSAGLDDKANAVLIVKPRTASFQRVSLSKRRLLN
CCCCCEEEEECCCCCCEEEEECCCHHHHCCCCCCCCEEEEECCCCCCHHHHHHHHHHHCC
SSTIFLHLVGQRKRVVLEQAMATNNPEILPICAILNAPDANVQVMYAPSDEEKECIL
CCEEEEEEECCHHHHHHHHHHHCCCCCEEEEEEEECCCCCCEEEEECCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10761919 [H]