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The map label for this gene is murA1 [H]

Identifier: 148360776

GI number: 148360776

Start: 704959

End: 706482

Strand: Direct

Name: murA1 [H]

Synonym: LPC_2726

Alternate gene names: 148360776

Gene position: 704959-706482 (Clockwise)

Preceding gene: 148360777

Following gene: 148360772

Centisome position: 19.71

GC content: 39.57

Gene sequence:

>1524_bases
ATGTTAAGCAAATATGAGCTAATTAAACCTGACATAGGATCCAGTCACGGCAATATCACAAAAGTGTATGAAATAGTCGG
CGGCAAACCGCTCAGAGGGCAAGTCAAAGTAAGCGGGTCTAAAAATGCTGCTCTGCCTGTACTGGCAGCGAGTTTATTAT
GCAAAGAGCCGCTGCAGTTAACCAATTTACCGAAAATATTAGATGTTACCAATATGATTCAATGCATGGAAGCATTAGGT
AAAAGATTTGAATTCATCAATACTAACACGATTAAAATTGGCAATAGAGAAATGGATACACTGACTATTCCAAAGGAGGC
AGCCAGACAAATTCGTGCTTCAATTATTTTATTAGGCCCTTTGGTTGCGCAGTATCCAAAGGTGATATTGCCATTACCAG
GTGGATGCTCTATTGGGAAACGTCCCATTGATTTGCACATCAGTGCGCTTAATGCTTTGGGTGTAGATATTGTTGAGCTA
CCAGATTGTTTAGTATGTTCTCGCCGTTATGCTCGGCTTCAAGGAAATACTATTAACTTTTCCATCAAGACTGTGACTGG
AACAGAAAATGCGATGATGGCTGCTGTATTGGCAGAAGGAACAACTATTATAAATAATGCTGCAATGGAACCCGAGATAG
TTGATTTGGCTAATTTTTTAAATAGGCTTGGAGCAAAAATTGATGGGGCGGGTAGCGACAGAATCACAATTTCCGGTGTA
GATAAATTAAATTCTTGTGGAAGTTATTCCATCATGGCAGATAGAATCGAGGCTGGTACCTATTTAGTAGCAGCAGCGAT
GACTCGCGGTTCTATTTCCGTTAAAGGAATCAATCCGGATTATCTGGTTGCAGTTTTGAGCGAATTAAAATGTGCAGGTG
CAAAAATTACCTGTGATTCTGACTCAATCCAGCTTGATATGGGAGAAGAGTATGGTGAATCGTTAAATATAACCACAAAA
CCCTATCCAGGCTTTCCAACAGATCTGCAATCTCTCTTTTTAAGTCTGACTTGTGTTTTAAGGGGTAACTCTTATTTGTG
TGAGACTCTATTTGAAGATCGTTTTCAAATAGTCCAAGAGCTTAAAAAAATGGGAGCCAATATTTCTTTAAAGGATAACA
CTGCCCACATAAAGGGTGTTTCAAGATTAAGGGGCTCTCAAGTCAATGCTACTGATTTACGCTCAGGTGCCGCTTTAGTA
TGCGCCAGTTTGGCAGCGGAGGGTATCACGCAGATTTTTGCCATAGAGCATATAGAGCGCGGTTATGAAGATTTAATATT
AAAATTAAAAGCACTTGGCGCCAATATTAAATTAATTGAGAATACCCATGTAACAAGCACGGAATTATCTGACAGTCATT
TCAAAGAGGCGACTAGTAGTGAAACTCGAATACAACGAGCATCGTTGATTGAAACCGTAGTAACACCATCTATAACAACA
TTTGGACAGTTTAAAAGAGTACCTACAGGAGAAGTGACGGAATTGGAAAAACAGCAGACACCTTATCTGCATCACATTAT
GTAA

Upstream 100 bases:

>100_bases
GTTATGGTTTGGAAGTATAGTGCTTTTATATGATAAAGCAGTATCAATAAGTAACAGACAAAAAGAGCTATAAGTATTTC
AAGATTAAGATGGGTGGTTA

Downstream 100 bases:

>100_bases
GGTATCTATCCTTTAATCTTATATAATGCCCGGCAGAATATTCAATTTGCTCTATCTCTTTTGTGGTCAATTTTCTGATG
GCTTGAGCAGGGCTTCCCAA

Product: UDP-N-acetylglucosamine 1-carboxyvinyltransferase

Products: NA

Alternate protein names: Enoylpyruvate transferase 1; UDP-N-acetylglucosamine enolpyruvyl transferase 1; EPT 1 [H]

Number of amino acids: Translated: 507; Mature: 507

Protein sequence:

>507_residues
MLSKYELIKPDIGSSHGNITKVYEIVGGKPLRGQVKVSGSKNAALPVLAASLLCKEPLQLTNLPKILDVTNMIQCMEALG
KRFEFINTNTIKIGNREMDTLTIPKEAARQIRASIILLGPLVAQYPKVILPLPGGCSIGKRPIDLHISALNALGVDIVEL
PDCLVCSRRYARLQGNTINFSIKTVTGTENAMMAAVLAEGTTIINNAAMEPEIVDLANFLNRLGAKIDGAGSDRITISGV
DKLNSCGSYSIMADRIEAGTYLVAAAMTRGSISVKGINPDYLVAVLSELKCAGAKITCDSDSIQLDMGEEYGESLNITTK
PYPGFPTDLQSLFLSLTCVLRGNSYLCETLFEDRFQIVQELKKMGANISLKDNTAHIKGVSRLRGSQVNATDLRSGAALV
CASLAAEGITQIFAIEHIERGYEDLILKLKALGANIKLIENTHVTSTELSDSHFKEATSSETRIQRASLIETVVTPSITT
FGQFKRVPTGEVTELEKQQTPYLHHIM

Sequences:

>Translated_507_residues
MLSKYELIKPDIGSSHGNITKVYEIVGGKPLRGQVKVSGSKNAALPVLAASLLCKEPLQLTNLPKILDVTNMIQCMEALG
KRFEFINTNTIKIGNREMDTLTIPKEAARQIRASIILLGPLVAQYPKVILPLPGGCSIGKRPIDLHISALNALGVDIVEL
PDCLVCSRRYARLQGNTINFSIKTVTGTENAMMAAVLAEGTTIINNAAMEPEIVDLANFLNRLGAKIDGAGSDRITISGV
DKLNSCGSYSIMADRIEAGTYLVAAAMTRGSISVKGINPDYLVAVLSELKCAGAKITCDSDSIQLDMGEEYGESLNITTK
PYPGFPTDLQSLFLSLTCVLRGNSYLCETLFEDRFQIVQELKKMGANISLKDNTAHIKGVSRLRGSQVNATDLRSGAALV
CASLAAEGITQIFAIEHIERGYEDLILKLKALGANIKLIENTHVTSTELSDSHFKEATSSETRIQRASLIETVVTPSITT
FGQFKRVPTGEVTELEKQQTPYLHHIM
>Mature_507_residues
MLSKYELIKPDIGSSHGNITKVYEIVGGKPLRGQVKVSGSKNAALPVLAASLLCKEPLQLTNLPKILDVTNMIQCMEALG
KRFEFINTNTIKIGNREMDTLTIPKEAARQIRASIILLGPLVAQYPKVILPLPGGCSIGKRPIDLHISALNALGVDIVEL
PDCLVCSRRYARLQGNTINFSIKTVTGTENAMMAAVLAEGTTIINNAAMEPEIVDLANFLNRLGAKIDGAGSDRITISGV
DKLNSCGSYSIMADRIEAGTYLVAAAMTRGSISVKGINPDYLVAVLSELKCAGAKITCDSDSIQLDMGEEYGESLNITTK
PYPGFPTDLQSLFLSLTCVLRGNSYLCETLFEDRFQIVQELKKMGANISLKDNTAHIKGVSRLRGSQVNATDLRSGAALV
CASLAAEGITQIFAIEHIERGYEDLILKLKALGANIKLIENTHVTSTELSDSHFKEATSSETRIQRASLIETVVTPSITT
FGQFKRVPTGEVTELEKQQTPYLHHIM

Specific function: Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine [H]

COG id: COG0766

COG function: function code M; UDP-N-acetylglucosamine enolpyruvyl transferase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the EPSP synthase family. MurA subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789580, Length=419, Percent_Identity=46.7780429594272, Blast_Score=364, Evalue=1e-102,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001986
- InterPro:   IPR013792
- InterPro:   IPR005750 [H]

Pfam domain/function: PF00275 EPSP_synthase [H]

EC number: =2.5.1.7 [H]

Molecular weight: Translated: 54869; Mature: 54869

Theoretical pI: Translated: 7.14; Mature: 7.14

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLSKYELIKPDIGSSHGNITKVYEIVGGKPLRGQVKVSGSKNAALPVLAASLLCKEPLQL
CCCCCCCCCCCCCCCCCCCEEEHHHHCCCCCCCEEEECCCCCCCHHHHHHHHHHCCCHHH
TNLPKILDVTNMIQCMEALGKRFEFINTNTIKIGNREMDTLTIPKEAARQIRASIILLGP
CCCCHHHHHHHHHHHHHHHHHHEEEECCCEEEECCCCCCEEECCHHHHHHHHHHHHEEHH
LVAQYPKVILPLPGGCSIGKRPIDLHISALNALGVDIVELPDCLVCSRRYARLQGNTINF
HHHHCCCEEEECCCCCCCCCCCEEEEEEEHHHCCCCHHHCCHHHHHHHHHHHHCCCEEEE
SIKTVTGTENAMMAAVLAEGTTIINNAAMEPEIVDLANFLNRLGAKIDGAGSDRITISGV
EEEEEECCCCHHHHHHHHCCCEEEECCCCCCHHHHHHHHHHHHCCEECCCCCCEEEEECC
DKLNSCGSYSIMADRIEAGTYLVAAAMTRGSISVKGINPDYLVAVLSELKCAGAKITCDS
HHCCCCCCCEEEHHHHCCCCEEEEEEECCCCEEEECCCHHHHHHHHHHHHHCCCEEEECC
DSIQLDMGEEYGESLNITTKPYPGFPTDLQSLFLSLTCVLRGNSYLCETLFEDRFQIVQE
CCEEEECCHHCCCCCCEECCCCCCCCHHHHHHHHHHHHEECCCCHHHHHHHHHHHHHHHH
LKKMGANISLKDNTAHIKGVSRLRGSQVNATDLRSGAALVCASLAAEGITQIFAIEHIER
HHHCCCCEEECCCCHHHHHHHHHCCCCCCHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHC
GYEDLILKLKALGANIKLIENTHVTSTELSDSHFKEATSSETRIQRASLIETVVTPSITT
CHHHHHHHHHHCCCCEEEEECCCCCCCCCCHHHHHHHCCHHHHHHHHHHHHHHHCCCCCC
FGQFKRVPTGEVTELEKQQTPYLHHIM
CHHHCCCCCCCHHHHHHHCCCCHHHCC
>Mature Secondary Structure
MLSKYELIKPDIGSSHGNITKVYEIVGGKPLRGQVKVSGSKNAALPVLAASLLCKEPLQL
CCCCCCCCCCCCCCCCCCCEEEHHHHCCCCCCCEEEECCCCCCCHHHHHHHHHHCCCHHH
TNLPKILDVTNMIQCMEALGKRFEFINTNTIKIGNREMDTLTIPKEAARQIRASIILLGP
CCCCHHHHHHHHHHHHHHHHHHEEEECCCEEEECCCCCCEEECCHHHHHHHHHHHHEEHH
LVAQYPKVILPLPGGCSIGKRPIDLHISALNALGVDIVELPDCLVCSRRYARLQGNTINF
HHHHCCCEEEECCCCCCCCCCCEEEEEEEHHHCCCCHHHCCHHHHHHHHHHHHCCCEEEE
SIKTVTGTENAMMAAVLAEGTTIINNAAMEPEIVDLANFLNRLGAKIDGAGSDRITISGV
EEEEEECCCCHHHHHHHHCCCEEEECCCCCCHHHHHHHHHHHHCCEECCCCCCEEEEECC
DKLNSCGSYSIMADRIEAGTYLVAAAMTRGSISVKGINPDYLVAVLSELKCAGAKITCDS
HHCCCCCCCEEEHHHHCCCCEEEEEEECCCCEEEECCCHHHHHHHHHHHHHCCCEEEECC
DSIQLDMGEEYGESLNITTKPYPGFPTDLQSLFLSLTCVLRGNSYLCETLFEDRFQIVQE
CCEEEECCHHCCCCCCEECCCCCCCCHHHHHHHHHHHHEECCCCHHHHHHHHHHHHHHHH
LKKMGANISLKDNTAHIKGVSRLRGSQVNATDLRSGAALVCASLAAEGITQIFAIEHIER
HHHCCCCEEECCCCHHHHHHHHHCCCCCCHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHC
GYEDLILKLKALGANIKLIENTHVTSTELSDSHFKEATSSETRIQRASLIETVVTPSITT
CHHHHHHHHHHCCCCEEEEECCCCCCCCCCHHHHHHHCCHHHHHHHHHHHHHHHCCCCCC
FGQFKRVPTGEVTELEKQQTPYLHHIM
CHHHCCCCCCCHHHHHHHCCCCHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA