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The map label for this gene is exuT [H]

Identifier: 148360708

GI number: 148360708

Start: 772969

End: 774252

Strand: Direct

Name: exuT [H]

Synonym: LPC_2655

Alternate gene names: 148360708

Gene position: 772969-774252 (Clockwise)

Preceding gene: 148360709

Following gene: 148360707

Centisome position: 21.61

GC content: 40.81

Gene sequence:

>1284_bases
ATGCAGGTAGTGGATGAATTTAAAGCATTCGATGTTAAAGCATCGCTAATGCCATGGCTGGTTTGTTTTGCAGCAACCAT
GTTTTTCTTTTATGAATTTATTCAGGGAAATATGTTTGCTTCCATTGCGGCAAATATCATGCAGGATTTTCAGATTCAAG
CAGATAAAATGGCTTACTTATCCAGCATCTATTACTTGGCAAATGTGATTTTTCTGTTTATTGCCGGAATGGTTTTGGAC
AGGTTTTCAATCAAAAACACCATTTTAATAGCTATGTTTCTGTGTGTGATTAGTACGTTTATCCTCTCCTACTCAGATTC
GTTTTATGTGGCTTTATTTTGCAGGTTTGTGACTGGAATAGGTAGCGCATTTTGCTTTTTGGGTCCCGTGCGTTTGGCGT
CTCATTGGTTTCCTCCCCAGCGTATGGCTTTAGTGACTGGCGCGATTGTAACTGTTGCAATGACAGGAGGAATGCTGGCG
CAATACCCCTTAACTAAACTGGTTCTACATGTTGGATGGCGCCAAGCAGTTCAAGACGTAGGGATATTGGGCTTGGCCAT
GTTAGTTCTCATGTTTTTTTGGATTAAAGAAAGACCTCAAGTCGCAATCAAAAAAGAAGGAAAACCTATCAATGTGCTTG
TGGCTGCAAGAAAAGCCTACTTAAATGCTCAAAATTTGCGAGCAGCCTTATACACTAGTCTTATGAACATGGCCATTGCT
GTATTTGGCGCCATGATGGGGACTTTATATCTTGAACAGAGATTAGGCATTAGCCCTGATCAGGCAGCTATGATCAACGG
TATGTTGTTTTTTGGAGCCATTATAGGTTCACCTTTGATGGGGTGGATATCTGATAAGGTAGGGTTGCGTGTGCTGCCTA
TGAAAGGGGGAGTCCTTGCCTCTTTACTTATTTTGCTGGGAGTACTTTATTTACCTGTTTCAGTGACAATGATGGCCGTA
TTGTTCTTTTTATTAGGATTATTTACTTCAGCTCAAGTCATTAGCTATGCCCTGGTTGCTGAAAGCAGCCCTCCCATGAT
GACTGCAACGGCTGTCAGTGTCGTGTCCATATTAACTCAAGGCGGGTATCTTATTTATCAAAACCTGTTTAGTGCTTTAT
TGACGAATTATGGCGATGTTCGTTTGATTAATGGTGTGCCAGTTTATTTACTCGAAGCGTATCAGCATGCAGCAATCATT
TTACCCATAGGATTATTGATCGCATTACTTTTATTGTTCGGATTAAAAGAAACTCGTTGCCAACAAGTTGGGCATACAGT
ATGA

Upstream 100 bases:

>100_bases
TCAATTTGCCATGTGGATGTTTCCTGTTGCCGCAATTGCAGGACTGGTTGCTGTGCTCATGACTCGTGAAACATACTGCA
AGCGATAGAGAGGAGAAATA

Downstream 100 bases:

>100_bases
CCGGACGAGTTTGCGTATTAGTAATGGATTCCTTTGGCATCGGAGCCAGCCTTGATGCCGCTCGGTATGGAGATGTGGGT
GCTAACACCTTGGTTCACAT

Product: major facilitator family transporter transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 427; Mature: 427

Protein sequence:

>427_residues
MQVVDEFKAFDVKASLMPWLVCFAATMFFFYEFIQGNMFASIAANIMQDFQIQADKMAYLSSIYYLANVIFLFIAGMVLD
RFSIKNTILIAMFLCVISTFILSYSDSFYVALFCRFVTGIGSAFCFLGPVRLASHWFPPQRMALVTGAIVTVAMTGGMLA
QYPLTKLVLHVGWRQAVQDVGILGLAMLVLMFFWIKERPQVAIKKEGKPINVLVAARKAYLNAQNLRAALYTSLMNMAIA
VFGAMMGTLYLEQRLGISPDQAAMINGMLFFGAIIGSPLMGWISDKVGLRVLPMKGGVLASLLILLGVLYLPVSVTMMAV
LFFLLGLFTSAQVISYALVAESSPPMMTATAVSVVSILTQGGYLIYQNLFSALLTNYGDVRLINGVPVYLLEAYQHAAII
LPIGLLIALLLLFGLKETRCQQVGHTV

Sequences:

>Translated_427_residues
MQVVDEFKAFDVKASLMPWLVCFAATMFFFYEFIQGNMFASIAANIMQDFQIQADKMAYLSSIYYLANVIFLFIAGMVLD
RFSIKNTILIAMFLCVISTFILSYSDSFYVALFCRFVTGIGSAFCFLGPVRLASHWFPPQRMALVTGAIVTVAMTGGMLA
QYPLTKLVLHVGWRQAVQDVGILGLAMLVLMFFWIKERPQVAIKKEGKPINVLVAARKAYLNAQNLRAALYTSLMNMAIA
VFGAMMGTLYLEQRLGISPDQAAMINGMLFFGAIIGSPLMGWISDKVGLRVLPMKGGVLASLLILLGVLYLPVSVTMMAV
LFFLLGLFTSAQVISYALVAESSPPMMTATAVSVVSILTQGGYLIYQNLFSALLTNYGDVRLINGVPVYLLEAYQHAAII
LPIGLLIALLLLFGLKETRCQQVGHTV
>Mature_427_residues
MQVVDEFKAFDVKASLMPWLVCFAATMFFFYEFIQGNMFASIAANIMQDFQIQADKMAYLSSIYYLANVIFLFIAGMVLD
RFSIKNTILIAMFLCVISTFILSYSDSFYVALFCRFVTGIGSAFCFLGPVRLASHWFPPQRMALVTGAIVTVAMTGGMLA
QYPLTKLVLHVGWRQAVQDVGILGLAMLVLMFFWIKERPQVAIKKEGKPINVLVAARKAYLNAQNLRAALYTSLMNMAIA
VFGAMMGTLYLEQRLGISPDQAAMINGMLFFGAIIGSPLMGWISDKVGLRVLPMKGGVLASLLILLGVLYLPVSVTMMAV
LFFLLGLFTSAQVISYALVAESSPPMMTATAVSVVSILTQGGYLIYQNLFSALLTNYGDVRLINGVPVYLLEAYQHAAII
LPIGLLIALLLLFGLKETRCQQVGHTV

Specific function: Aldohexuronate transport system [H]

COG id: COG0477

COG function: function code GEPR; Permeases of the major facilitator superfamily

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Phthalate permease family [H]

Homologues:

Organism=Escherichia coli, GI87082310, Length=349, Percent_Identity=23.4957020057307, Blast_Score=62, Evalue=9e-11,
Organism=Drosophila melanogaster, GI28574037, Length=278, Percent_Identity=22.6618705035971, Blast_Score=66, Evalue=5e-11,
Organism=Drosophila melanogaster, GI281364404, Length=278, Percent_Identity=22.6618705035971, Blast_Score=65, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004744
- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 46919; Mature: 46919

Theoretical pI: Translated: 9.17; Mature: 9.17

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
5.9 %Met     (Translated Protein)
7.0 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
5.9 %Met     (Mature Protein)
7.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHCCCCC
>Mature Secondary Structure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HHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9579062; 9384377 [H]