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The map label for this gene is cyaA [H]

Identifier: 148360673

GI number: 148360673

Start: 834144

End: 835457

Strand: Direct

Name: cyaA [H]

Synonym: LPC_2619

Alternate gene names: 148360673

Gene position: 834144-835457 (Clockwise)

Preceding gene: 148360674

Following gene: 148360670

Centisome position: 23.32

GC content: 39.95

Gene sequence:

>1314_bases
GTGGATAGTTACTCTAAGTTACCGCTTCGCATCAGGAAAGAGATAGAAGCCCAACAATACACTGGTGAACTATTGGTTGC
CGGCGTCCAGTTGGGTGTCATTGTATTATTAAGCATTATCAATATATTTTCTTCAGCTGGCTATTCGCCTGGCGCGCCGG
TGCAATCATCATCTCTAGGCTTATGGCTATTTGCTATTTTGATATTACTAAGGCTGTGGTTTGTCTATACTAATCAATTA
AATCCAATATTCTTGGGATTCTTTATAGTCGCCGAAATGGCTTTGTTATTATTTATTATTTGGACTTATTATTTGCAGTT
CGAAACCACACCTACTATTAATCTTAAAAATCCGCATATTAACTATGTTTATGTTTTAATTGCTTTGCGTGCGCTTCGAT
TTGAACCATTATGGGTAATTCTCTCTGGCCTCACTGCGGCTCTTGGCTGGGGAATTATTGCCTGGCAAACTTTATCCAGT
TCGGGTATGAATGTTATTACATGGGATTATGTGACATTCGCGTCAACTCGGAGTGTCTATCTGGGAGCTGTATTTGATGT
CATATTGTCCGTTCTACTGGTTACTACCATCATAGCCTTGGTATTGACGCGTGCGAAACACACTCTGTTTCAAGCAGTAG
AACAAACTAGCGCTGCAAAAGATTTATCACGTTTTTTTGATACAAGTGTGGTCGAAAAAATAACAACATCTGAAAAGTCA
TTGCAAGCTGGATATGGCGAGCTTCGTCAGGCTGCAATTATGTTCATTGATATGCGAGGATTTACCAAAGCATCAGTGAA
ACTGTCCCCGAGTGAACTAATCGGACTGCTAGCAGAATATCAACGCTTACTGGTTCCGATTATTCAAAAGAATAATGGCA
GCATTGATAAATTCATGGGGGATGGTATTTTGGCAAGTTTCGGTGCTGTGACCCCTTCAAATACTTATGCAGCAGATGCA
TTAAGGACTGTGGATGAAATTGTCGCATCGGTAGACGTATGGAGTGAAAATCGCCGTAAAAAAGAACAGATAGTGGTCGG
TGTAGGAATTGGTCTTGCTTCAGGTGAAGTAGTAGTTGGTGTCATTGGTTATGAAAATCGTTTGGAATATACTGTAATTG
GCGAAGCTGCCAATTTAGCTGCAAAGCTTGAAAAACATAATAAGGAAGAAAAAACCCAGGCTTTGACTACCCGGGATACT
TTTTTAGAAGCGGTAAAACAAGGTTATGAGGACAAAATAACTAAGAAGGAATTGAATGCAAGAAATGTAGGTGGTGTGGG
AGAACCTTTGGATTTAGTGGTATTGGCAAAATAA

Upstream 100 bases:

>100_bases
TCCCAGCATTCTTGTGCTGCGCAATCAACGGCCGATCGTGATCCTGAAGCATTTATCATGTTACCTAAAGGGTTATGCGA
ACGCATAGTGGGGGGAAGGA

Downstream 100 bases:

>100_bases
CCCATATTGTTCTTCACGGTTATTCAGGACAGTTGTTAGCGTGAGTCAAATGATAATTAGAATGAATAAAAGAATCTTCC
AATAATTCATTTCTTAGTAA

Product: adenylate cyclase

Products: NA

Alternate protein names: ATP pyrophosphate-lyase 1; Adenylyl cyclase 1; AC 1 [H]

Number of amino acids: Translated: 437; Mature: 437

Protein sequence:

>437_residues
MDSYSKLPLRIRKEIEAQQYTGELLVAGVQLGVIVLLSIINIFSSAGYSPGAPVQSSSLGLWLFAILILLRLWFVYTNQL
NPIFLGFFIVAEMALLLFIIWTYYLQFETTPTINLKNPHINYVYVLIALRALRFEPLWVILSGLTAALGWGIIAWQTLSS
SGMNVITWDYVTFASTRSVYLGAVFDVILSVLLVTTIIALVLTRAKHTLFQAVEQTSAAKDLSRFFDTSVVEKITTSEKS
LQAGYGELRQAAIMFIDMRGFTKASVKLSPSELIGLLAEYQRLLVPIIQKNNGSIDKFMGDGILASFGAVTPSNTYAADA
LRTVDEIVASVDVWSENRRKKEQIVVGVGIGLASGEVVVGVIGYENRLEYTVIGEAANLAAKLEKHNKEEKTQALTTRDT
FLEAVKQGYEDKITKKELNARNVGGVGEPLDLVVLAK

Sequences:

>Translated_437_residues
MDSYSKLPLRIRKEIEAQQYTGELLVAGVQLGVIVLLSIINIFSSAGYSPGAPVQSSSLGLWLFAILILLRLWFVYTNQL
NPIFLGFFIVAEMALLLFIIWTYYLQFETTPTINLKNPHINYVYVLIALRALRFEPLWVILSGLTAALGWGIIAWQTLSS
SGMNVITWDYVTFASTRSVYLGAVFDVILSVLLVTTIIALVLTRAKHTLFQAVEQTSAAKDLSRFFDTSVVEKITTSEKS
LQAGYGELRQAAIMFIDMRGFTKASVKLSPSELIGLLAEYQRLLVPIIQKNNGSIDKFMGDGILASFGAVTPSNTYAADA
LRTVDEIVASVDVWSENRRKKEQIVVGVGIGLASGEVVVGVIGYENRLEYTVIGEAANLAAKLEKHNKEEKTQALTTRDT
FLEAVKQGYEDKITKKELNARNVGGVGEPLDLVVLAK
>Mature_437_residues
MDSYSKLPLRIRKEIEAQQYTGELLVAGVQLGVIVLLSIINIFSSAGYSPGAPVQSSSLGLWLFAILILLRLWFVYTNQL
NPIFLGFFIVAEMALLLFIIWTYYLQFETTPTINLKNPHINYVYVLIALRALRFEPLWVILSGLTAALGWGIIAWQTLSS
SGMNVITWDYVTFASTRSVYLGAVFDVILSVLLVTTIIALVLTRAKHTLFQAVEQTSAAKDLSRFFDTSVVEKITTSEKS
LQAGYGELRQAAIMFIDMRGFTKASVKLSPSELIGLLAEYQRLLVPIIQKNNGSIDKFMGDGILASFGAVTPSNTYAADA
LRTVDEIVASVDVWSENRRKKEQIVVGVGIGLASGEVVVGVIGYENRLEYTVIGEAANLAAKLEKHNKEEKTQALTTRDT
FLEAVKQGYEDKITKKELNARNVGGVGEPLDLVVLAK

Specific function: Unknown

COG id: COG2114

COG function: function code T; Adenylate cyclase, family 3 (some proteins contain HAMP domain)

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 guanylate cyclase domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001054 [H]

Pfam domain/function: PF00211 Guanylate_cyc [H]

EC number: =4.6.1.1 [H]

Molecular weight: Translated: 48175; Mature: 48175

Theoretical pI: Translated: 6.83; Mature: 6.83

Prosite motif: PS50125 GUANYLATE_CYCLASES_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDSYSKLPLRIRKEIEAQQYTGELLVAGVQLGVIVLLSIINIFSSAGYSPGAPVQSSSLG
CCCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCH
LWLFAILILLRLWFVYTNQLNPIFLGFFIVAEMALLLFIIWTYYLQFETTPTINLKNPHI
HHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHEECCCCEEECCCCCC
NYVYVLIALRALRFEPLWVILSGLTAALGWGIIAWQTLSSSGMNVITWDYVTFASTRSVY
HHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEHEEHHCHHHHH
LGAVFDVILSVLLVTTIIALVLTRAKHTLFQAVEQTSAAKDLSRFFDTSVVEKITTSEKS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHH
LQAGYGELRQAAIMFIDMRGFTKASVKLSPSELIGLLAEYQRLLVPIIQKNNGSIDKFMG
HHHHHHHHHHHHEEEEEECCCCEEEEEECHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHC
DGILASFGAVTPSNTYAADALRTVDEIVASVDVWSENRRKKEQIVVGVGIGLASGEVVVG
CCHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHEEEEEEEEEECCCCEEEE
VIGYENRLEYTVIGEAANLAAKLEKHNKEEKTQALTTRDTFLEAVKQGYEDKITKKELNA
EECCCCCEEEEEECCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCC
RNVGGVGEPLDLVVLAK
CCCCCCCCCCCEEEEEC
>Mature Secondary Structure
MDSYSKLPLRIRKEIEAQQYTGELLVAGVQLGVIVLLSIINIFSSAGYSPGAPVQSSSLG
CCCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCH
LWLFAILILLRLWFVYTNQLNPIFLGFFIVAEMALLLFIIWTYYLQFETTPTINLKNPHI
HHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHEECCCCEEECCCCCC
NYVYVLIALRALRFEPLWVILSGLTAALGWGIIAWQTLSSSGMNVITWDYVTFASTRSVY
HHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEHEEHHCHHHHH
LGAVFDVILSVLLVTTIIALVLTRAKHTLFQAVEQTSAAKDLSRFFDTSVVEKITTSEKS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHH
LQAGYGELRQAAIMFIDMRGFTKASVKLSPSELIGLLAEYQRLLVPIIQKNNGSIDKFMG
HHHHHHHHHHHHEEEEEECCCCEEEEEECHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHC
DGILASFGAVTPSNTYAADALRTVDEIVASVDVWSENRRKKEQIVVGVGIGLASGEVVVG
CCHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHEEEEEEEEEECCCCEEEE
VIGYENRLEYTVIGEAANLAAKLEKHNKEEKTQALTTRDTFLEAVKQGYEDKITKKELNA
EECCCCCEEEEEECCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCC
RNVGGVGEPLDLVVLAK
CCCCCCCCCCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9523018; 8418825 [H]