Click here to switch to the map view.

The map label for this gene is alr [H]

Identifier: 148360608

GI number: 148360608

Start: 918095

End: 919168

Strand: Direct

Name: alr [H]

Synonym: LPC_2554

Alternate gene names: 148360608

Gene position: 918095-919168 (Clockwise)

Preceding gene: 148360609

Following gene: 148360607

Centisome position: 25.67

GC content: 45.34

Gene sequence:

>1074_bases
GTGTCAAGACCTACACGTTTAGTGATAGAGCCCAGTGCTTTATTGCATAATTTATCTCAAATCAAGCATTTAGCTCCAGG
CAAAAAAGTTATCGCTATGGTAAAAGCCAACGCCTATGGCTGTGGAGTCAGGGAAGTTGCCCCTGTCCTTGATGGGCGTA
TTGAGGCTTTTGGAGTAGCCTGCCTTGAAGAGGCTCTGGCTATTCGAGCTTTAGGTGTTGAAACCCCGTGCATTCTCTTT
CAGGGCGTCTTTAGTTCTGATGAATTGTCAGTAGCCGTTGAGAATGATTTCGCCTGTGTTCTTCATCACGCACAGCAGTT
GGAATGGCTAATCAAGACTCCGTTGCCTTACCCGATAAAAGTATGGGTGAAGGTAAACACAGGCATGCACAGACTGGGAT
TTAAAATCCATGAATTGCAAAAAGTGATGGGGGCATTGCAAACCTGTACCTGGGTTGATAAAAGTATAGGGTTAATGACT
CATTTGGCTTGCGCAGATGAACCTCATCGTCCTGAGAATCAACAACAGATCTCTTTGTTTCAGGAGATATCCATACCTGG
GTTTCGCCAACGCAGTATCGCTAATTCGGCGGCAATTATTTCATTCCCTGATTCGCAGGCTGATGTGGTGAGGCCCGGGA
TTATGTTGTATGGTGTTTCCCCATTTGCAAATCAAAATGCCCATGATTTAGGTTTAATCCCTGTCATGCGTTTTATGTCA
GCCATCAGCGCGATTCATGATAACCCATCTTTTGCCCAGGTAGGCTATGGTGGAACCTGGAAAAGTGATAAACCTTCGCG
AATTGGTGTTGTTGCAGCAGGTTATGGCGATGGGTACCCACGGCATATTTCCGAGAAAACACCGGTTTGGGTTAGAGGGA
GGGAGGTGTCTATTGTTGGCAGAGTTTCTATGGATATGCTGACCATCGATTTGACAGAGCACCCTGATGTTGAGATCGGC
GATGAAGTTGAGCTTTGGGGAACACATGTTTTAGTAGAGCGCATTGCCAAATCAGCAGGTACAGTAGGATACGAATTATT
ATGTCAAATTTCGGAGAGAGTACGTTACAAATAA

Upstream 100 bases:

>100_bases
CAAAGAAATGGACCCATAGGCAAAGTCAGGGTAGCCTTTTTGGGTAAGTACACACGATTTGAAGATTTGGCATTTAATGG
TTATCAAGGGGTAGAATAGG

Downstream 100 bases:

>100_bases
GTTATGGATAATAACTGTTCGTGATGGTAGAATGACAACCGATTTTGTAACTCTTTAAACAGGTGAACTGTAATGAAAAA
ATTAATTGTTGCATCATTAT

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 357; Mature: 356

Protein sequence:

>357_residues
MSRPTRLVIEPSALLHNLSQIKHLAPGKKVIAMVKANAYGCGVREVAPVLDGRIEAFGVACLEEALAIRALGVETPCILF
QGVFSSDELSVAVENDFACVLHHAQQLEWLIKTPLPYPIKVWVKVNTGMHRLGFKIHELQKVMGALQTCTWVDKSIGLMT
HLACADEPHRPENQQQISLFQEISIPGFRQRSIANSAAIISFPDSQADVVRPGIMLYGVSPFANQNAHDLGLIPVMRFMS
AISAIHDNPSFAQVGYGGTWKSDKPSRIGVVAAGYGDGYPRHISEKTPVWVRGREVSIVGRVSMDMLTIDLTEHPDVEIG
DEVELWGTHVLVERIAKSAGTVGYELLCQISERVRYK

Sequences:

>Translated_357_residues
MSRPTRLVIEPSALLHNLSQIKHLAPGKKVIAMVKANAYGCGVREVAPVLDGRIEAFGVACLEEALAIRALGVETPCILF
QGVFSSDELSVAVENDFACVLHHAQQLEWLIKTPLPYPIKVWVKVNTGMHRLGFKIHELQKVMGALQTCTWVDKSIGLMT
HLACADEPHRPENQQQISLFQEISIPGFRQRSIANSAAIISFPDSQADVVRPGIMLYGVSPFANQNAHDLGLIPVMRFMS
AISAIHDNPSFAQVGYGGTWKSDKPSRIGVVAAGYGDGYPRHISEKTPVWVRGREVSIVGRVSMDMLTIDLTEHPDVEIG
DEVELWGTHVLVERIAKSAGTVGYELLCQISERVRYK
>Mature_356_residues
SRPTRLVIEPSALLHNLSQIKHLAPGKKVIAMVKANAYGCGVREVAPVLDGRIEAFGVACLEEALAIRALGVETPCILFQ
GVFSSDELSVAVENDFACVLHHAQQLEWLIKTPLPYPIKVWVKVNTGMHRLGFKIHELQKVMGALQTCTWVDKSIGLMTH
LACADEPHRPENQQQISLFQEISIPGFRQRSIANSAAIISFPDSQADVVRPGIMLYGVSPFANQNAHDLGLIPVMRFMSA
ISAIHDNPSFAQVGYGGTWKSDKPSRIGVVAAGYGDGYPRHISEKTPVWVRGREVSIVGRVSMDMLTIDLTEHPDVEIGD
EVELWGTHVLVERIAKSAGTVGYELLCQISERVRYK

Specific function: Provides the D-alanine required for cell wall biosynthesis [H]

COG id: COG0787

COG function: function code M; Alanine racemase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the alanine racemase family [H]

Homologues:

Organism=Escherichia coli, GI1790487, Length=352, Percent_Identity=43.4659090909091, Blast_Score=285, Evalue=3e-78,
Organism=Escherichia coli, GI1787439, Length=356, Percent_Identity=38.2022471910112, Blast_Score=235, Evalue=3e-63,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000821
- InterPro:   IPR009006
- InterPro:   IPR011079
- InterPro:   IPR001608 [H]

Pfam domain/function: PF00842 Ala_racemase_C; PF01168 Ala_racemase_N [H]

EC number: =5.1.1.1 [H]

Molecular weight: Translated: 39279; Mature: 39148

Theoretical pI: Translated: 6.99; Mature: 6.99

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSRPTRLVIEPSALLHNLSQIKHLAPGKKVIAMVKANAYGCGVREVAPVLDGRIEAFGVA
CCCCCEEEECHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCHHHHHHHHCCCHHHHHHH
CLEEALAIRALGVETPCILFQGVFSSDELSVAVENDFACVLHHAQQLEWLIKTPLPYPIK
HHHHHHHHHHCCCCCCEEEEEECCCCCCEEEEECCCHHHHHHHHHHHHHHHCCCCCCCEE
VWVKVNTGMHRLGFKIHELQKVMGALQTCTWVDKSIGLMTHLACADEPHRPENQQQISLF
EEEEECCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHH
QEISIPGFRQRSIANSAAIISFPDSQADVVRPGIMLYGVSPFANQNAHDLGLIPVMRFMS
HHCCCCCCHHHHCCCCEEEEECCCCCCHHHCCCEEEEECCCCCCCCCCCCHHHHHHHHHH
AISAIHDNPSFAQVGYGGTWKSDKPSRIGVVAAGYGDGYPRHISEKTPVWVRGREVSIVG
HHHHHCCCCCEEECCCCCCCCCCCCCEEEEEEECCCCCCCCCCCCCCCEEEECCEEEEEE
RVSMDMLTIDLTEHPDVEIGDEVELWGTHVLVERIAKSAGTVGYELLCQISERVRYK
EEEEEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SRPTRLVIEPSALLHNLSQIKHLAPGKKVIAMVKANAYGCGVREVAPVLDGRIEAFGVA
CCCCEEEECHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCHHHHHHHHCCCHHHHHHH
CLEEALAIRALGVETPCILFQGVFSSDELSVAVENDFACVLHHAQQLEWLIKTPLPYPIK
HHHHHHHHHHCCCCCCEEEEEECCCCCCEEEEECCCHHHHHHHHHHHHHHHCCCCCCCEE
VWVKVNTGMHRLGFKIHELQKVMGALQTCTWVDKSIGLMTHLACADEPHRPENQQQISLF
EEEEECCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHH
QEISIPGFRQRSIANSAAIISFPDSQADVVRPGIMLYGVSPFANQNAHDLGLIPVMRFMS
HHCCCCCCHHHHCCCCEEEEECCCCCCHHHCCCEEEEECCCCCCCCCCCCHHHHHHHHHH
AISAIHDNPSFAQVGYGGTWKSDKPSRIGVVAAGYGDGYPRHISEKTPVWVRGREVSIVG
HHHHHCCCCCEEECCCCCCCCCCCCCEEEEEEECCCCCCCCCCCCCCCEEEECCEEEEEE
RVSMDMLTIDLTEHPDVEIGDEVELWGTHVLVERIAKSAGTVGYELLCQISERVRYK
EEEEEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA