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The map label for this gene is ccmC [H]

Identifier: 148360496

GI number: 148360496

Start: 1039104

End: 1039847

Strand: Direct

Name: ccmC [H]

Synonym: LPC_2437

Alternate gene names: 148360496

Gene position: 1039104-1039847 (Clockwise)

Preceding gene: 148360497

Following gene: 148360495

Centisome position: 29.05

GC content: 40.86

Gene sequence:

>744_bases
TTGTATCAGTTGGCATCGCCAAAAAATTTTTATAACTACGCGGGACGTCTCATTCCCTGGCTGGCAGTCAGTGCTTTAGC
TACCATAGCCATTGGTATGGTTTGGGGGTTGGTATTTGCTCCACCAGATTATCAGCAAGGGGATGCATACCGAATTATTT
TTGTTCATGTGCCTAGCGCTTTTTTATCAATGGCATTGTATGCCTGGATGGGGTTTCTGGCCATTTTATTGTTGGTGTGG
CGTATCAAAATGGCAGGGCTTTTGATTCATAAAGTTGCGCAATTAGGTGCCTGCATGGCATTTCTTGCTTTAATTACAGG
GAGCATTTGGGGTAAACCCATGTGGGGTGCCTGGTGGGTATGGGATGCGCGCCTGACCTCAGAGCTAATACTTTTGTTAC
TCTATCTGGCAATTCTGGCTACCTACCAAGCGGTAAAAAATAAAGAAGATGGAGATAAAATAATAGCAATTTTAGCTTTG
GTGGGCTTAATTGATTTACCAATAATTCATTATTCAGTTTATTGGTGGAATACCTTACACCAAGGTGCGACTTTATCTGT
GTTTGCCAAACCCAAAATTGCTCTCAGTATGTTGTATCCTTTGTTAATCACTTTGCTGGGTTTTTTCTTGTATTCCTTAT
GGATCATTTTGGAAAAAGCACGTAATGAAGTCTTATTCAGGGAGAGAAAGCAATCATGGGTTAAGGTTCAATTTGAGGAA
GAGTCTGATGAATCAGTTTTTTGA

Upstream 100 bases:

>100_bases
GACCCTAAGTTTGGAACTAAATTTTGTGATTGTTTTGTGATTGTTTTGATGCGTGGTAGAATCCTTCTTTTTGATTTTAT
TGTTTCCTATGTGGAAGATA

Downstream 100 bases:

>100_bases
ATGGTTGGCAATGGGCGGTTATTCTCTCTATGTTTGGCCTGCTTATGGTTTGGTTTGCGTGGTTTTGGGCATGAATATTT
TAGGAATAAAGTGGCAAAGA

Product: heme exporter protein CcmC

Products: NA

Alternate protein names: Cytochrome c-type biogenesis protein CcmC [H]

Number of amino acids: Translated: 247; Mature: 247

Protein sequence:

>247_residues
MYQLASPKNFYNYAGRLIPWLAVSALATIAIGMVWGLVFAPPDYQQGDAYRIIFVHVPSAFLSMALYAWMGFLAILLLVW
RIKMAGLLIHKVAQLGACMAFLALITGSIWGKPMWGAWWVWDARLTSELILLLLYLAILATYQAVKNKEDGDKIIAILAL
VGLIDLPIIHYSVYWWNTLHQGATLSVFAKPKIALSMLYPLLITLLGFFLYSLWIILEKARNEVLFRERKQSWVKVQFEE
ESDESVF

Sequences:

>Translated_247_residues
MYQLASPKNFYNYAGRLIPWLAVSALATIAIGMVWGLVFAPPDYQQGDAYRIIFVHVPSAFLSMALYAWMGFLAILLLVW
RIKMAGLLIHKVAQLGACMAFLALITGSIWGKPMWGAWWVWDARLTSELILLLLYLAILATYQAVKNKEDGDKIIAILAL
VGLIDLPIIHYSVYWWNTLHQGATLSVFAKPKIALSMLYPLLITLLGFFLYSLWIILEKARNEVLFRERKQSWVKVQFEE
ESDESVF
>Mature_247_residues
MYQLASPKNFYNYAGRLIPWLAVSALATIAIGMVWGLVFAPPDYQQGDAYRIIFVHVPSAFLSMALYAWMGFLAILLLVW
RIKMAGLLIHKVAQLGACMAFLALITGSIWGKPMWGAWWVWDARLTSELILLLLYLAILATYQAVKNKEDGDKIIAILAL
VGLIDLPIIHYSVYWWNTLHQGATLSVFAKPKIALSMLYPLLITLLGFFLYSLWIILEKARNEVLFRERKQSWVKVQFEE
ESDESVF

Specific function: Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes [H]

COG id: COG0755

COG function: function code O; ABC-type transport system involved in cytochrome c biogenesis, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CcmC/CycZ/HelC family [H]

Homologues:

Organism=Escherichia coli, GI1788527, Length=235, Percent_Identity=48.0851063829787, Blast_Score=234, Evalue=3e-63,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002541
- InterPro:   IPR003557 [H]

Pfam domain/function: PF01578 Cytochrom_C_asm [H]

EC number: NA

Molecular weight: Translated: 28164; Mature: 28164

Theoretical pI: Translated: 9.13; Mature: 9.13

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYQLASPKNFYNYAGRLIPWLAVSALATIAIGMVWGLVFAPPDYQQGDAYRIIFVHVPSA
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEEEECCHH
FLSMALYAWMGFLAILLLVWRIKMAGLLIHKVAQLGACMAFLALITGSIWGKPMWGAWWV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEE
WDARLTSELILLLLYLAILATYQAVKNKEDGDKIIAILALVGLIDLPIIHYSVYWWNTLH
EHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
QGATLSVFAKPKIALSMLYPLLITLLGFFLYSLWIILEKARNEVLFRERKQSWVKVQFEE
CCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECC
ESDESVF
CCCCCCC
>Mature Secondary Structure
MYQLASPKNFYNYAGRLIPWLAVSALATIAIGMVWGLVFAPPDYQQGDAYRIIFVHVPSA
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEEEECCHH
FLSMALYAWMGFLAILLLVWRIKMAGLLIHKVAQLGACMAFLALITGSIWGKPMWGAWWV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEE
WDARLTSELILLLLYLAILATYQAVKNKEDGDKIIAILALVGLIDLPIIHYSVYWWNTLH
EHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
QGATLSVFAKPKIALSMLYPLLITLLGFFLYSLWIILEKARNEVLFRERKQSWVKVQFEE
CCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECC
ESDESVF
CCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]