Click here to switch to the map view.

The map label for this gene is ccmE [H]

Identifier: 148360494

GI number: 148360494

Start: 1039995

End: 1040426

Strand: Direct

Name: ccmE [H]

Synonym: LPC_2435

Alternate gene names: 148360494

Gene position: 1039995-1040426 (Clockwise)

Preceding gene: 148360495

Following gene: 148360493

Centisome position: 29.08

GC content: 40.05

Gene sequence:

>432_bases
ATGAACCCTGTACGGCGACGCAAATTATTTATCTTACTGTTTGCCCTGACTATTTTATCTGCAGCGGCTGCCCTGGTTCT
ATATGCCTTAAGACAAAATATCAGTTTATTTTACACCCCCACTCAGATTGTTGCGGGAGAAGCACCAGTAAAACACCACA
TCCGAGTTGGAGGTATGGTGGAAGCAAATAGCATAGTACGTGCCAAAAAAGGTTTGGATGTCCAGTTTAAAATTACAGAT
TTTGAAAACACGATTGTTGTTACCTATTCAGGGATACTTCCCGATTTATTTCGAGAAGGGCAAGGAATAGTTGCGGAAGG
AGAAGTAACTGATAATCATCATTTTCATGCTATACAAGTTTTGGCAAAACACGATGCCAATTATATGCCACCTCAAGTAA
AGTCTGCTTTAGCTGATAAGGTGAAACAATGA

Upstream 100 bases:

>100_bases
GTTTGGTTTGCGTGGTTTTGGGCATGAATATTTTAGGAATAAAGTGGCAAAGAACTCGTACCCGCAAAAAATTACAACGT
TGGTTTAAGAGATAGGTTAA

Downstream 100 bases:

>100_bases
TAGCGGAATTAGGACTGTTTTTTTTGATTTTGGCTTTAGTGGCTTCTTTGATGTTAGCTTTGATCCCATTGGCGGGTTTG
CAATTCAATCGGAAAGACTG

Product: cytochrome c-type biogenesis protein CcmE

Products: NA

Alternate protein names: Cytochrome c maturation protein E; Heme chaperone CcmE [H]

Number of amino acids: Translated: 143; Mature: 143

Protein sequence:

>143_residues
MNPVRRRKLFILLFALTILSAAAALVLYALRQNISLFYTPTQIVAGEAPVKHHIRVGGMVEANSIVRAKKGLDVQFKITD
FENTIVVTYSGILPDLFREGQGIVAEGEVTDNHHFHAIQVLAKHDANYMPPQVKSALADKVKQ

Sequences:

>Translated_143_residues
MNPVRRRKLFILLFALTILSAAAALVLYALRQNISLFYTPTQIVAGEAPVKHHIRVGGMVEANSIVRAKKGLDVQFKITD
FENTIVVTYSGILPDLFREGQGIVAEGEVTDNHHFHAIQVLAKHDANYMPPQVKSALADKVKQ
>Mature_143_residues
MNPVRRRKLFILLFALTILSAAAALVLYALRQNISLFYTPTQIVAGEAPVKHHIRVGGMVEANSIVRAKKGLDVQFKITD
FENTIVVTYSGILPDLFREGQGIVAEGEVTDNHHFHAIQVLAKHDANYMPPQVKSALADKVKQ

Specific function: Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH [H]

COG id: COG2332

COG function: function code O; Cytochrome c-type biogenesis protein CcmE

Gene ontology:

Cell location: Cell inner membrane; Single-pass type II membrane protein; Periplasmic side (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CcmE/CycJ family [H]

Homologues:

Organism=Escherichia coli, GI1788525, Length=143, Percent_Identity=48.2517482517483, Blast_Score=134, Evalue=2e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004329
- InterPro:   IPR012340 [H]

Pfam domain/function: PF03100 CcmE [H]

EC number: NA

Molecular weight: Translated: 15847; Mature: 15847

Theoretical pI: Translated: 10.00; Mature: 10.00

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNPVRRRKLFILLFALTILSAAAALVLYALRQNISLFYTPTQIVAGEAPVKHHIRVGGMV
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCHHEEECCCCCHHEEEECCEE
EANSIVRAKKGLDVQFKITDFENTIVVTYSGILPDLFREGQGIVAEGEVTDNHHFHAIQV
ECCHHHHHHCCCCEEEEEECCCCEEEEEECCCCHHHHHCCCCEEEECCCCCCCCHHHHHH
LAKHDANYMPPQVKSALADKVKQ
HHHCCCCCCCHHHHHHHHHHHCC
>Mature Secondary Structure
MNPVRRRKLFILLFALTILSAAAALVLYALRQNISLFYTPTQIVAGEAPVKHHIRVGGMV
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCHHEEECCCCCHHEEEECCEE
EANSIVRAKKGLDVQFKITDFENTIVVTYSGILPDLFREGQGIVAEGEVTDNHHFHAIQV
ECCHHHHHHCCCCEEEEEECCCCEEEEEECCCCHHHHHCCCCEEEECCCCCCCCHHHHHH
LAKHDANYMPPQVKSALADKVKQ
HHHCCCCCCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA