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The map label for this gene is yafC [C]

Identifier: 148360190

GI number: 148360190

Start: 2845058

End: 2845963

Strand: Reverse

Name: yafC [C]

Synonym: LPC_2122

Alternate gene names: 148360190

Gene position: 2845963-2845058 (Counterclockwise)

Preceding gene: 148360188

Following gene: 148360191

Centisome position: 79.57

GC content: 34.77

Gene sequence:

>906_bases
ATGATAAACAATTCACTTAATCTAAATGATTTGGCAATTTTTGCATTAGTAGTAAAAAAGCGAAGCTTTACTCAAGCCGC
ATTGGAGGCTGGGATTTCCAAAGCATGGGTCAGTCAAAAAATCTCTCAGTTGGAGGGTAAGCTTGATATAAAATTACTTA
ACAGAACCACGCGTTCTTTAAGTCTTACTCTAGGTGGTGAAATTTTATTTGAACATTGCCAAGCCATGTTGAAAGAAGTG
ATTCATGCTGAAAATCATTTGCGGGAATACGCTAAGGCACCTTCTGGAAAGCTGGTTATTACCTGTCCTGAGATTTCAGG
TTTAGACTTATTTCCTGCCTTATTGCATCAGTTTAAATTACTTTATCCTCAAATCAAGATTCGTTTAATTATTACCGATC
AATTTGTGGATTTAACCCAGCAGGGCATTGATTTTGCCTTTAGAACCGGGAAATTGACTGACTCGGGATTAGTATCCCGC
TATATTGGAGCAGTGCCACGATGCTTAGTCGCCTCCCCTGAATATTTATCTAATAATTCACCAATCAAAAGTCCAGCAGA
TTTGTTTAATCATCAGCTGCTAAAACATAGCTCCTTGCCTGATTGGCTTTTAAAAAAGGAGGAAGAGGCATTTAAAATAC
ATGTTAAAAATCCTGTAATAGAAAGTAATTCCTTAATTTTTTTGCATAAAATGTCATGCCTTCATCATGGTATTGCCTTT
CTGCCTTACTATTTATGTTCAGATGCTTTGAAACACAAAACCTTGGTTAAGGTATTACCTGATTGGCTTAATGTGGATAA
TGAGTATTATATGGTATATCACAAAGAAAAAAGCGTTCTTTATATACATCAATTGTTTAAAGATTTTATATTGCAATCTG
ATTTAAACAAAATGATTTCAAATTAG

Upstream 100 bases:

>100_bases
TAAAACGCATGATAGCTCCTGGTTATTGTATATCAAGCGTTAATGATATAGATTAGCCAATTAATTGATTAGACCAAATA
ATATAAACTCATTGTTCGCT

Downstream 100 bases:

>100_bases
GCGCGAATAAACCCAAAAATCAAGAAATACATCTTGCCTATGTCTGATTTTGTCTATGTGTTAATGGAACGCAGAAGCCG
AAATAAAACCAGTGAATTTG

Product: LysR family transporter transcriptional regulator

Products: NA

Alternate protein names: ORF2 [H]

Number of amino acids: Translated: 301; Mature: 301

Protein sequence:

>301_residues
MINNSLNLNDLAIFALVVKKRSFTQAALEAGISKAWVSQKISQLEGKLDIKLLNRTTRSLSLTLGGEILFEHCQAMLKEV
IHAENHLREYAKAPSGKLVITCPEISGLDLFPALLHQFKLLYPQIKIRLIITDQFVDLTQQGIDFAFRTGKLTDSGLVSR
YIGAVPRCLVASPEYLSNNSPIKSPADLFNHQLLKHSSLPDWLLKKEEEAFKIHVKNPVIESNSLIFLHKMSCLHHGIAF
LPYYLCSDALKHKTLVKVLPDWLNVDNEYYMVYHKEKSVLYIHQLFKDFILQSDLNKMISN

Sequences:

>Translated_301_residues
MINNSLNLNDLAIFALVVKKRSFTQAALEAGISKAWVSQKISQLEGKLDIKLLNRTTRSLSLTLGGEILFEHCQAMLKEV
IHAENHLREYAKAPSGKLVITCPEISGLDLFPALLHQFKLLYPQIKIRLIITDQFVDLTQQGIDFAFRTGKLTDSGLVSR
YIGAVPRCLVASPEYLSNNSPIKSPADLFNHQLLKHSSLPDWLLKKEEEAFKIHVKNPVIESNSLIFLHKMSCLHHGIAF
LPYYLCSDALKHKTLVKVLPDWLNVDNEYYMVYHKEKSVLYIHQLFKDFILQSDLNKMISN
>Mature_301_residues
MINNSLNLNDLAIFALVVKKRSFTQAALEAGISKAWVSQKISQLEGKLDIKLLNRTTRSLSLTLGGEILFEHCQAMLKEV
IHAENHLREYAKAPSGKLVITCPEISGLDLFPALLHQFKLLYPQIKIRLIITDQFVDLTQQGIDFAFRTGKLTDSGLVSR
YIGAVPRCLVASPEYLSNNSPIKSPADLFNHQLLKHSSLPDWLLKKEEEAFKIHVKNPVIESNSLIFLHKMSCLHHGIAF
LPYYLCSDALKHKTLVKVLPDWLNVDNEYYMVYHKEKSVLYIHQLFKDFILQSDLNKMISN

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1786401, Length=286, Percent_Identity=32.1678321678322, Blast_Score=138, Evalue=4e-34,
Organism=Escherichia coli, GI1789639, Length=273, Percent_Identity=30.03663003663, Blast_Score=134, Evalue=9e-33,
Organism=Escherichia coli, GI87081978, Length=276, Percent_Identity=31.5217391304348, Blast_Score=130, Evalue=2e-31,
Organism=Escherichia coli, GI1787128, Length=280, Percent_Identity=31.0714285714286, Blast_Score=129, Evalue=3e-31,
Organism=Escherichia coli, GI1787589, Length=277, Percent_Identity=28.5198555956679, Blast_Score=117, Evalue=9e-28,
Organism=Escherichia coli, GI145693193, Length=291, Percent_Identity=27.1477663230241, Blast_Score=98, Evalue=5e-22,
Organism=Escherichia coli, GI1789173, Length=286, Percent_Identity=28.6713286713287, Blast_Score=96, Evalue=2e-21,
Organism=Escherichia coli, GI1789440, Length=279, Percent_Identity=25.089605734767, Blast_Score=84, Evalue=1e-17,
Organism=Escherichia coli, GI1788481, Length=145, Percent_Identity=28.9655172413793, Blast_Score=68, Evalue=8e-13,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 34284; Mature: 34284

Theoretical pI: Translated: 8.88; Mature: 8.88

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MINNSLNLNDLAIFALVVKKRSFTQAALEAGISKAWVSQKISQLEGKLDIKLLNRTTRSL
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCEE
SLTLGGEILFEHCQAMLKEVIHAENHLREYAKAPSGKLVITCPEISGLDLFPALLHQFKL
EEEECHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCHHHHHHHHHHHH
LYPQIKIRLIITDQFVDLTQQGIDFAFRTGKLTDSGLVSRYIGAVPRCLVASPEYLSNNS
HCCEEEEEEEEEHHHHHHHHHCCHHEEECCCCCCHHHHHHHHHHCCHHHHCCCHHHCCCC
PIKSPADLFNHQLLKHSSLPDWLLKKEEEAFKIHVKNPVIESNSLIFLHKMSCLHHGIAF
CCCCHHHHHHHHHHHHCCCCHHHHCCCCCEEEEEECCCEECCCCEEEEEHHHHHHHHHHH
LPYYLCSDALKHKTLVKVLPDWLNVDNEYYMVYHKEKSVLYIHQLFKDFILQSDLNKMIS
HHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHC
N
C
>Mature Secondary Structure
MINNSLNLNDLAIFALVVKKRSFTQAALEAGISKAWVSQKISQLEGKLDIKLLNRTTRSL
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCEE
SLTLGGEILFEHCQAMLKEVIHAENHLREYAKAPSGKLVITCPEISGLDLFPALLHQFKL
EEEECHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCHHHHHHHHHHHH
LYPQIKIRLIITDQFVDLTQQGIDFAFRTGKLTDSGLVSRYIGAVPRCLVASPEYLSNNS
HCCEEEEEEEEEHHHHHHHHHCCHHEEECCCCCCHHHHHHHHHHCCHHHHCCCHHHCCCC
PIKSPADLFNHQLLKHSSLPDWLLKKEEEAFKIHVKNPVIESNSLIFLHKMSCLHHGIAF
CCCCHHHHHHHHHHHHCCCCHHHHCCCCCEEEEEECCCEECCCCEEEEEHHHHHHHHHHH
LPYYLCSDALKHKTLVKVLPDWLNVDNEYYMVYHKEKSVLYIHQLFKDFILQSDLNKMIS
HHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHC
N
C

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8635745; 7542800 [H]